Efficacy, immunogenicity and stability of a novel intranasal nanoemulsion-adjuvanted influenza vaccine in a murine modelTarek Hamouda
NanoBio Corp, Ann Arbor, MI, USA
Hum Vaccin 6:585-94. 2010
..The nanoemulsion adjuvant can result in antigen sparing and cross-protection. The potential exists for a nasally administered influenza vaccine that may require little or no refrigerated storage...
Intranasal immunization of ferrets with commercial trivalent influenza vaccines formulated in a nanoemulsion-based adjuvantTarek Hamouda
NanoBio Corp, 2311 Green Road, Suite A, Ann Arbor, MI 48105, USA
Clin Vaccine Immunol 18:1167-75. 2011
..These findings demonstrate the ability of W(80)5EC NE to adjuvant nasally administered influenza vaccine and provide a basis for studying the intranasal W(80)5EC-adjuvanted influenza vaccine in humans...
Development of immune response that protects mice from viral pneumonitis after a single intranasal immunization with influenza A virus and nanoemulsionAndrzej Myc
Department of Internal Medicine, Division of Allergy, Center of Biologic Nanotechnology, University of Michigan, 9240 MSRB III, Ann Arbor, MI 48109-0666, USA
Vaccine 21:3801-14. 2003
..This paper demonstrates that nanoemulsion can be employed as a non-toxic mucosal adjuvant for influenza virus vaccine...
The fungicidal activity of novel nanoemulsion (X8W60PC) against clinically important yeast and filamentous fungiAndrzej Myc
Department of Internal Medicine, Division of Allergy, Center for Biologic Nanotechnology, University of Michigan, Ann Arbor, MI, USA
Mycopathologia 155:195-201. 2002
..This shows that the nanoemulsion structure is an important factor in the anti-fungal activity. The X8W60PC has great potential as a topical anti-fungal agent and further investigation into the mechanism of fungicidal action is warranted...
Topical nanoemulsion therapy reduces bacterial wound infection and inflammation after burn injuryMark R Hemmila
Department of Surgery, University of Michigan Medical School, Ann Arbor, MI 48109 5033, USA
Surgery 148:499-509. 2010
..In addition to reducing infection, nanoemulsion therapy may modulate dermal inflammatory signaling and thereby lessen inflammation following thermal injury...
Prevention of influenza pneumonitis by sialic Acid-conjugated dendritic polymersJeffrey J Landers
Center for Biologic Nanotechnology, Department of Internal Medicine, Division of Allergy, University of Michigan, Ann Arbor, Michigan 48109, USA
J Infect Dis 186:1222-30. 2002
..Polyvalent binding inhibitors have potential as antiviral therapeutics, but issues related to strain specificity must be resolved...
In vitro antibacterial activity of NB-003 against Propionibacterium acnesJ Pannu
NanoBio Corporation, 2311 Green Rd, Suite A, Ann Arbor, MI 48105, USA
Antimicrob Agents Chemother 55:4211-7. 2011
..Electron micrographs of P. acnes treated with NB-003 showed complete disruption of bacteria. Assessment of spontaneous resistance of P. acnes revealed no stably resistant mutant strains...