Tal Grenader

..It is very unusual for this kind of tumor to induce clinically apparent tumor lysis syndrome (TLS) which is a consequence of spontaneous cytolysis or massive tumor cell lysis, beginning a few hours after the initiation of treatment...

..Conclusion: On the basis of this small retrospective survey, we conclude that CMFVP combination chemotherapy is both effective and safe in patients with metastatic breast cancer previously treated with both taxanes and anthracyclines...

..We report on a patient with known non-small-cell lung cancer who developed Staphylococcus aureus bacteremia secondary to severe erlotinib skin toxicity...

..This review considers the literature related to the risk of developing a second cancer in patients with male breast cancer...

..3-0.8% of all malignant melanomas. True amelanotic vaginal melanoma showing no melanin on histological examination is exceedingly rare, accounting for only 2% of all vaginal melanomas...

..We describe a patient who developed febrile neutropenia with testicular abscess when treated with BEP 2 weeks following inguinal orchiectomy...

..PLD is active and safe for long-term treatment of metastatic STSs and may be important in maintaining response...

..6 mg/dl (10.2 micromol/dl) and his liver function tests returned to near normal levels. The combination was well tolerated and clinical improvement continued for more than 11 months before disease progression was observed...

..Despite the early and widespread dissemination of nonsmall cell lung cancer, clinically significant metastases in the small bowel are rare, and when they do occur, the patient is almost always in the terminal stages of the disease...

..In metastatic patients with no evidence of cardiac risk factors, it may be sufficient to measure LVEF at baseline...

..5 years following cessation of treatment with vinorelbine...

..6%. A histological examination of a specimen from a lytic lesion of the spine was consistent with metastatic breast cancer and a needle biopsy of the prostate showed adenocarcinoma, Gleason score 3 + 4...

..We report a case in which a potential drug interaction resulted in elevated phenytoin levels after initiation of erlotinib therapy in a patient who was receiving phenytoin...

..The patient received high-dose steroids intravenously with no response. A 5-day course of intravenous immunoglobulin resulted in gradual decrease of the pericardial effusion and resolution of cardiac tamponade within 2 weeks...

..Prophylactic surgical options and intensified surveillance should, of course, be discussed with these patients...

..Eighteen months after the arteriography, the patient had stable renal function with creatinine levels of 150-160 micromol/L, and he was asymptomatic...

..The pathological diagnosis of the tumor was consistent with metastatic prostate carcinoma. Further evaluation revealed widespread bony metastases by technetium 99 bone scan and high level of prostate-specific antigen...

..Metastatic testicular cancer can be associated with a variety of complications due to obstruction or invasion of adjacent structures. This is a case study of 2 patients with testicular cancer who presented with venous thromboembolism...

..However, total occlusion of the aorta is very unusual. We describe two patients with atherosclerotic vascular disease who developed occlusion of the abdominal aorta after cisplatin-based chemotherapy...

..Metastatic breast cancer has a substantial mortality burden on women worldwide. Presented herein is our experience with the combination of mitomycin-C and vinblastine in heavily pretreated breast cancer patients...

..The Breast Cancer Linkage Consortium (BCLC) reported approximately 2.6-fold increase in the risk for CMM among BRCA2 carrier families...

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..We report a patient with cardiac myxoma who presented with acute onset of bilateral lower limb ischemia and total occlusion of the abdominal aorta by a large saddle embolus...

..We report a patient with metastatic renal cell carcinoma who developed almost complete obstruction of the trachea and who was successfully managed with bronchoscopic resection of endotracheal metastases...

..The enriched clinical experience with PLD has further strengthened its added value with regard to both safety and efficacy in the management of a broad variety of malignancies...