Georgia Salanti

Summary

Affiliation: University of Ioannina
Country: Greece

Publications

  1. ncbi A nonparametric changepoint model for stratifying continuous variables under order restrictions and binary outcome
    Georgia Salanti
    Institute for Medical Statistics and Epidemiology, Klinikum rechts der Isar, Munich, Germany
    Stat Methods Med Res 12:351-67. 2003
  2. ncbi Bayesian synthesis of epidemiological evidence with different combinations of exposure groups: application to a gene-gene-environment interaction
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge, U K
    Stat Med 25:4147-63. 2006
  3. ncbi Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial
    Georgia Salanti
    Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    J Clin Epidemiol 64:163-71. 2011
  4. ncbi Meta-analysis of genetic association studies under different inheritance models using data reported as merged genotypes
    Georgia Salanti
    Clinical and Molecular Epidemiology Unit, University of Ioannina School of Medicine, Ioannina, Greece
    Stat Med 27:764-77. 2008
  5. ncbi Evaluating novel agent effects in multiple-treatments meta-regression
    Georgia Salanti
    Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    Stat Med 29:2369-83. 2010
  6. ncbi A case study of multiple-treatments meta-analysis demonstrates that covariates should be considered
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge, UK
    J Clin Epidemiol 62:857-64. 2009
  7. ncbi Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer
    Davide Mauri
    Clinical Trials and Evidence Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    J Natl Cancer Inst 100:1780-91. 2008
  8. ncbi Bayesian meta-analysis and meta-regression for gene-disease associations and deviations from Hardy-Weinberg equilibrium
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge, UK
    Stat Med 26:553-67. 2007
  9. ncbi Family-based versus unrelated case-control designs for genetic associations
    Evangelos Evangelou
    Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    PLoS Genet 2:e123. 2006
  10. ncbi A road map for efficient and reliable human genome epidemiology
    John P A Ioannidis
    Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, and Biomedical Research Institute, Foundation for Research and Technology Hellas, Ioannina 45110, Greece
    Nat Genet 38:3-5. 2006

Detail Information

Publications25

  1. ncbi A nonparametric changepoint model for stratifying continuous variables under order restrictions and binary outcome
    Georgia Salanti
    Institute for Medical Statistics and Epidemiology, Klinikum rechts der Isar, Munich, Germany
    Stat Methods Med Res 12:351-67. 2003
    ..An application will outline the benefit of using bivariate step functions in modelling...
  2. ncbi Bayesian synthesis of epidemiological evidence with different combinations of exposure groups: application to a gene-gene-environment interaction
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge, U K
    Stat Med 25:4147-63. 2006
    ..The methodology is implemented in an original meta-analysis of studies relating the risk of bladder cancer to two N-acetyltransferase genes, NAT1 and NAT2, and smoking status...
  3. ncbi Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial
    Georgia Salanti
    Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    J Clin Epidemiol 64:163-71. 2011
    ..To present some simple graphical and quantitative ways to assist interpretation and improve presentation of results from multiple-treatment meta-analysis (MTM)...
  4. ncbi Meta-analysis of genetic association studies under different inheritance models using data reported as merged genotypes
    Georgia Salanti
    Clinical and Molecular Epidemiology Unit, University of Ioannina School of Medicine, Ioannina, Greece
    Stat Med 27:764-77. 2008
    ....
  5. ncbi Evaluating novel agent effects in multiple-treatments meta-regression
    Georgia Salanti
    Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    Stat Med 29:2369-83. 2010
    ....
  6. ncbi A case study of multiple-treatments meta-analysis demonstrates that covariates should be considered
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge, UK
    J Clin Epidemiol 62:857-64. 2009
    ....
  7. ncbi Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer
    Davide Mauri
    Clinical Trials and Evidence Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    J Natl Cancer Inst 100:1780-91. 2008
    ..Many systemic nonhormonal regimens have been evaluated across several hundreds of randomized trials in advanced breast cancer. We aimed to quantify the relative merits of these regimens in prolonging survival...
  8. ncbi Bayesian meta-analysis and meta-regression for gene-disease associations and deviations from Hardy-Weinberg equilibrium
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge, UK
    Stat Med 26:553-67. 2007
    ..The proposed hierarchical models allow the synthesis of data across gene-disease association studies with appropriate consideration of HWE issues...
  9. ncbi Family-based versus unrelated case-control designs for genetic associations
    Evangelos Evangelou
    Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    PLoS Genet 2:e123. 2006
    ..Conclusions were largely similar in diverse subgroup analyses. Unrelated case-control and family-based designs give overall similar estimates of association. We cannot rule out rare large biases or common small biases...
  10. ncbi A road map for efficient and reliable human genome epidemiology
    John P A Ioannidis
    Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, and Biomedical Research Institute, Foundation for Research and Technology Hellas, Ioannina 45110, Greece
    Nat Genet 38:3-5. 2006
    ..Systematic reviews will be expanded to include more meta-analyses of individual-level data and prospective meta-analyses. Field synopses will offer regularly updated overviews...
  11. ncbi Synthesis of observational studies should consider credibility ceilings
    Georgia Salanti
    The Clinical Trials and Evidence Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina, School of Medicine, Ioannina, Greece
    J Clin Epidemiol 62:115-22. 2009
    ..Meta-analyses of observational studies often get spuriously precise results. We aimed to factor this skepticism in meta-analysis calculations...
  12. ncbi Evaluation of networks of randomized trials
    Georgia Salanti
    Clinical and Molecular Epidemiology Unit and Clinical Trials and Evidence Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Greece
    Stat Methods Med Res 17:279-301. 2008
    ..Finally, we discuss the implications of inconsistency, network geometry and asymmetry in informing the planning of future trials...
  13. ncbi Impact of violations and deviations in Hardy-Weinberg equilibrium on postulated gene-disease associations
    Thomas A Trikalinos
    Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina 45100, Greece
    Am J Epidemiol 163:300-9. 2006
    ..Postulated genetic associations with modest-sized odds ratios and borderline statistical significance may not be robust in such sensitivity analyses...
  14. ncbi Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis
    Vassilis Golfinopoulos
    Division of Medical Oncology, University of Ioannina School of Medicine, Ioannina, Greece
    Lancet Oncol 8:898-911. 2007
    ..The aim of our study was to estimate the magnitude of survival and disease progression benefits with the use of different regimens in patients with advanced colorectal cancer...
  15. ncbi Hardy-Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations, and power
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge University, Cambridge, UK
    Eur J Hum Genet 13:840-8. 2005
    ..Moreover, power is limited for HWE testing in most current genetic association studies...
  16. ncbi Underlying genetic models of inheritance in established type 2 diabetes associations
    Georgia Salanti
    Clinical and Molecular Epidemiology Unit and Clinical Trials and Evidence Based Medicine Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece
    Am J Epidemiol 170:537-45. 2009
    ..Information on the genetic model of robustly replicated association signals derived from genome-wide association studies may be useful for predictive modeling and for designing biologic and functional experiments...
  17. ncbi Exploring the geometry of treatment networks
    Georgia Salanti
    University of Ioannina School of Medicine, Ioannina, Greece
    Ann Intern Med 148:544-53. 2008
    ..Several treatment options exist for many conditions. Randomized trial evidence on the relative merits of various options may be missing or biased...
  18. ncbi Homophily and co-occurrence patterns shape randomized trials agendas: illustration in antifungal agents
    Evangelos C Rizos
    Department of Internal Medicine, University Hospital of Ioannina, Ioannina, Greece
    J Clin Epidemiol 64:830-42. 2011
    ..To assess whether there are preferences and avoidances for specific comparisons in a clinical trials agenda...
  19. ncbi A non-parametric framework for estimating threshold limit values
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge, UK
    BMC Med Res Methodol 5:36. 2005
    ..To estimate a threshold limit value for a compound known to have harmful health effects, an 'elbow' threshold model is usually applied. We are interested on non-parametric flexible alternatives...
  20. ncbi A network of investigator networks in human genome epidemiology
    John P A Ioannidis
    Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    Am J Epidemiol 162:302-4. 2005
    ....
  21. ncbi Obstacles and opportunities in meta-analysis of genetic association studies
    Georgia Salanti
    MRC Biostatistics Unit, Cambridge, UK
    Genet Med 7:13-20. 2005
    ..We believe that systematic review and meta-analysis has an important role to play in understanding genetic association studies and should help us to separate the wheat from the chaff...
  22. ncbi Autologous chondrocyte implantation for the treatment of cartilage lesions of the knee: a systematic review of randomized studies
    Haris S Vasiliadis
    Department of Orthopaedics, School of Medicine, University of Ioannina, Orthopaedic Sports Medicine Center, Ioannina, Greece
    Knee Surg Sports Traumatol Arthrosc 18:1645-55. 2010
    ..However, there is insufficient data to say whether ACI is superior to other treatment strategies. More high quality studies and harmonization in the reported outcomes are needed before specific suggestions for practice can be made...
  23. ncbi Turning the pump handle: evolving methods for integrating the evidence on gene-disease association
    Julian P T Higgins
    Am J Epidemiol 166:863-6. 2007
  24. ncbi Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis
    Simon Sanderson
    Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom
    Am J Epidemiol 166:741-51. 2007
    ..73 (95% CI: 1.70, 4.31). The importance of considering joint effects between genetic and environmental factors in the etiology of common complex diseases is underlined...
  25. ncbi The emergence of networks in human genome epidemiology: challenges and opportunities
    Daniela Seminara
    Epidemiology and Genetics Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, EPN Bldg, Rm. 5142, MSC 7393, 6130 Executive Blvd, Bethesda, MD 20892, USA
    Epidemiology 18:1-8. 2007