Research Topics
Species | Michael RentzosSummaryAffiliation: University of Athens Country: Greece Publications
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Publications
Alterations of T cell subsets in ALS: a systemic immune activation?M Rentzos
Department of Neurology, Aeginition Hospital, School of Medicine, Athens National University, Greece
Acta Neurol Scand 125:260-4. 2012..There is evidence that immunological factors may involved in pathogenetic mechanisms of amyotrophic lateral sclerosis (ALS). Few studies to date have explored the status of the systemic immune response in patients with ALS...- The role of IL-15 in central nervous system disordersM Rentzos
Department of Neurology, Aeginition Hospital, Athens National University, School of Medicine, Greece
Acta Neurol Scand 125:77-82. 2012..IL-15 may be involved in the inflammatory reactions and microglial activation of some common CNS disorders such as multiple sclerosis, Alzheimer's and Parkinson's disease, but its exact role in their pathogenesis is not clear... - Chronic inflammatory demyelinating polyneuropathy: a 6-year retrospective clinical study of a hospital-based populationM Rentzos
Department of Neurology, Aeginition Hospital, Athens Medical School, Vass Sophias av 72 74, 11528, Athens, Greece
J Clin Neurosci 14:229-35. 2007..In conclusion, CIDP is a clinically heterogeneous disorder. It is one of the few serious chronic neuropathies that has a good (although not permanent) treatment response... - Circulating interleukin-15 in dementia disordersMichael Rentzos
Department of Neurology, Aeginition Hospital, Athens National University, School of Medicine, 72 74 Vas Sophias Avenue, Athens 11528, Greece
J Neuropsychiatry Clin Neurosci 19:318-25. 2007..An immune hyporesponsiveness at some point during disease development may be responsible for the lower levels of IL-15 and other cytokines in Alzheimer's disease patients... - RANTES levels are elevated in serum and cerebrospinal fluid in patients with amyotrophic lateral sclerosisMichael Rentzos
Neurology, Aeginition Hospital, Athens National University, School of Medicine, Athens, Greece
Amyotroph Lateral Scler 8:283-7. 2007..007). No correlation of serum and CSF RANTES levels with disease duration was found. These results may suggest an activated microglia induced recruitment of peripheral inflammatory cells to sites of inflammation in ALS patients... - Circulating interleukin-15 and RANTES chemokine in Parkinson's diseaseM Rentzos
Department of Neurology, School of Medicine, Athens National University, Aeginition Hospital, 72 74 Vas Sophias Avenue, Athens, Greece
Acta Neurol Scand 116:374-9. 2007..RANTES is a C-C beta chemokine with strong chemoattractant activity for T lymphocytes and monocytes... - Effect of treatment with methylprednisolone on the serum levels of IL-12, IL-10 and CCL2 chemokine in patients with multiple sclerosis in relapseMichael Rentzos
Department of Neurology, Aeginition Hospital, Athens National University, School of Medicine, Greece
Clin Neurol Neurosurg 110:992-6. 2008..The mechanisms responsible for the beneficial effects of IVmethylprednisolone in attacks are not clearly established and the duration of the effect of this treatment remains controversial... - Circulating interleukin-10 and interleukin-12 in Parkinson's diseaseM Rentzos
Department of Neurology, School of Medicine, Athens National University, Athens, Greece
Acta Neurol Scand 119:332-7. 2009..Recent studies demonstrated the neuroprotective effect of IL-10. There is little information about the involvement of IL-12 or IL-10 in the pathophysiology of Parkinson's disease (PD)... - Circulating interleukin-15 and RANTES chemokine in MS patients: effect of treatment with methylprednisolone in patients with relapseMichael Rentzos
Department of Neurology, Aeginition Hospital, Athens Medical School, Athens, Greece
Neurol Res 32:684-9. 2010..Interleukin-15 (IL-15) is a proinflammatory cytokine. RANTES is a member of the beta chemokines subfamily with strong chemoattractant activity for T lymphocytes and monocytes... - Interleukin-17 and interleukin-23 are elevated in serum and cerebrospinal fluid of patients with ALS: a reflection of Th17 cells activation?M Rentzos
Department of Neurology, Aeginition Hospital, Athens National University, School of Medicine, Athens, Greece
Acta Neurol Scand 122:425-9. 2010..Th17 cells are characterized by predominant production of IL-17 and are suggested to be crucial in destructive autoimmunity. Interleukin-23 (IL-23) appears to play a supporting role in the continued stimulation and survival of Th17... - Interleukin-12 is reduced in cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementiaMichael Rentzos
Department of Neurology, Aeginition Hospital, Athens National University, School of Medicine, 72 74 Vas Sophias Ave, Athens 11528, Greece
J Neurol Sci 249:110-4. 2006..There is little information about the involvement of IL-12 in the pathophysiology of Alzheimer's disease (AD) and other tauopathies... - IL-15 is elevated in cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementiaM Rentzos
Department of Neurology, Aeginition Hospital Athens Medical School
J Geriatr Psychiatry Neurol 19:114-7. 2006..48, P = .05). Our findings suggest that interleukin-15 may be implicated in the pathophysiology of Alzheimer's disease and frontotemporal dementia... - The role of soluble intercellular adhesion molecules in neurodegenerative disordersM Rentzos
Department of Neurology, Aeginition Hospital, Athens Medical School, 72 74 Vas Sophias Av, Greece
J Neurol Sci 228:129-35. 2005..Adhesion molecules are markers of activated endothelial cells upregulated by action of cytokines... - Unusual association of multiple sclerosis with monoclonal gammopathy of undetermined significance (MGUS): two case reportsMichael Rentzos
Department of Neurology, Aeginition Hospital Athens Medical School, Athens, Greece
Funct Neurol 19:253-6. 2004..This association is very unusual and it is not certain whether the co-occurrence of these disorders might be the result of a causal link between multiple sclerosis and monoclonal gammopathy or a fortuitous phenomenon... - Serum levels of soluble intercellular adhesion molecule-1 (s-ICAM-1) and soluble endothelial leukocyte adhesion molecule-1(s-ELAM-1) in amyotrophic lateral sclerosisM Rentzos
Department of Neurology, Aeginition Hospital Athens Medical School, Greece
Amyotroph Lateral Scler Other Motor Neuron Disord 6:118-21. 2005..Soluble E-selectin is a glycoprotein which is considered an exclusive marker of endothelial activation. Its low level in our study may suggest a neural rather than an endothelial s-ICAM origin in patients with ALS... - Serum uric acid and multiple sclerosisM Rentzos
Department of Neurology, Aeginition Hospital Athens Medical School, 72 74 Vas Sophias Av, Greece
Clin Neurol Neurosurg 108:527-31. 2006..We also tried to investigate serum UA changes during treatment with immunomodulating or immunosuppressing drugs in the last 6 months... - IL-15 is elevated in serum and cerebrospinal fluid of patients with multiple sclerosisM Rentzos
Department of Neurology, Aeginition Hospital Athens Medical School, 72 74 Vas So phias Av, Greece
J Neurol Sci 241:25-9. 2006..CSF IL-15/Serum IL-15 ratio (c/s IL-15 ratio) was introduced to assess the origin of elevated IL-15 levels... - Serum levels of soluble intercellular adhesion molecule-1 and soluble endothelial leukocyte adhesion molecule-1 in Alzheimer's diseaseM Rentzos
Department of Neurology, Aeginition Hospital, Athens Medical School, Vass Sophias av 72 74, 11528 Athens, Greece
J Geriatr Psychiatry Neurol 17:225-31. 2004..47 and P< .17, respectively), seem to suggest the neural rather than the endothelial s-ICAM origin in patients with AD... - Interleukin-15 and interleukin-12 are elevated in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosisMichael Rentzos
Department of Neurology, Aeginition Hospital, Athens National University, School of Medicine, Athens, Greece mrentzos med uoa gr
Eur Neurol 63:285-90. 2010..Interleukin (IL)-15 and IL-12 are proinflammatory cytokines produced by activated blood and glial cells. They promote T cell differentiation and proliferation... - Folate and vitamin B12 levels in levodopa-treated Parkinson's disease patients: their relationship to clinical manifestations, mood and cognitionNikolaos I Triantafyllou
Department of Neurology, Aeginition Hospital, Athens University Medical School, Athens, Greece
Parkinsonism Relat Disord 14:321-5. 2008..In conclusion, lower folate levels were associated with depression, while lower vitamin B12 levels were associated with cognitive impairment. The effects of vitamin supplementation merit further attention and investigation... - Serum uric acid levels in patients with Parkinson's disease: their relationship to treatment and disease durationElisabeth Andreadou
Department of Neurology A, Athens National and Kapodistrian University, Aeginition Hospital, 74, 11528 Athens, Greece
Clin Neurol Neurosurg 111:724-8. 2009..In addition low plasma uric acid (UA) levels have been associated with an increased risk of PD... - Soluble interleukin-6 receptor (sIL-6R) in cerebrospinal fluid of patients with inflammatory and non inflammatory neurological diseasesMaria Michalopoulou
Department of Biopathology, Aeginition Hospital, Athens Medical School, Av. Vas, Sofias 72-74, Greece
Immunol Lett 94:183-9. 2004..66 indicate intrathecal increase of sIL-6R and might be used as an indicator of neuroimmunoregulatory and inflammatory processes in the central nervous system (CNS)... - The impact of comorbidity and other clinical and sociodemographic factors on health-related quality of life in Greek patients with Parkinson's diseaseElisabeth Andreadou
1st Department of Neurology, Medical School, Athens National and Kapodistrian University, Aeginition Hospital, Greece
Aging Ment Health 15:913-21. 2011.... - Superficial siderosis of central nervous system mimicking multiple sclerosisG K Papadimas
Department of Neurology, School of Medicine, Athens National University, Aeginition Hospital, Athens, Greece
Neurologist 15:153-5. 2009..Root avulsion due to traumatic plexus injury has been recognized as an extremely rare cause of hemosiderin deposition on leptomeninges and subpial layers of brain and spinal cord parenchyma... - An unusual case of insomnia associated with Whipple encephalopathy: first case reported from GreeceM Papadopoulou
Department of Neurology, University of Athens Medical School, Eginition Hospital, 74 Vas Sophias Av, 11528, Athens, Greece
Neurol Sci 26:174-7. 2005..Our case supports the finding that carbamazepine might be useful in the treatment of insomnia associated with Whipple encephalopathy... - Reply to "The role of soluble interleukin-6 receptor in inflammatory diseases" [Immunol Lett 2005;98(1):171]Maria Michalopoulou
Immunol Lett 105:99. 2006..We suggest a discrepancy between sIL-6R concentrations and measurable IL-6/sIL-6R complex, not excluding the positive contribution of sIL-6R as a marker of neuro-immunoregulatory and inflammatory status in the central nervous system... - Cerebral Whipple's disease diagnosed using PCR: the first case reported from GreeceMarianna Papadopoulou
Department of Neurology, Medical School of Athens, Aeginition Hospital, Athens, Greece
Mol Diagn 7:209-11. 2003....