Georgios Pappas

..Nevertheless, in the interest of literacy and of avoiding panic, physicians and the public both should be aware of the most common zoonosis worldwide...

..We review these films and underline the possible effect that they have on the public's perception of infection--a perception that, when misguided, could prove to be problematic in times of epidemics...

..Overall, attempts at controlling disease without altering the socioeconomic and political correlations may prove futile, unfortunately projecting similar fates for attempts related to more important communicable diseases...

..SXT may represent a cost-effective alternative weapon against MRSA. Its utility against this increasingly threatening pathogen need clarification through further clinical trials...

..This article investigates the differences in approved indications between these 2 bodies for a series of antimicrobial agents approved during the past decade...

..Recognition of intervening factors and proper assessment of the actual risk might augment in proper distribution of interest and funds on relevant medical research...

..Reviewing existing attempts at the development of such a vaccine, the authors conclude that a trivalent subcellular vaccine may be needed for adequate efficacy...

..To evaluate the long-term outcome of patients with adult-onset Still's disease (AOSD)...

..The authors sought to evaluate specialists' and physicians' attitude towards regimens used, non-medical aspects, and future trends in human brucellosis treatment...

..In vitro studies have outlined potential antimicrobial candidates such as macrolides and ketolides. Development of a globally accepted subunit vaccine for humans is warranted but is not expected in the near future...

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..Globalization, in the context of international travel, particularly for recreational activities and military expeditions, has led to increased exposure of individuals from the developed world to the disease, as recent outbreaks show...

..This raises important issues for future research, implying that the pathogen may actually be non-eradicable...

..Treatment duration should be individualized in the absence of an adequate cut-off index...

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..Public health initiatives can address the public's fears by increasing health literacy, which can contribute to reducing stigmatization...

..This may allow the disease to be neglected no longer, or at least to be recognised as neglected...

..We present a brief review of the relevant literature and, in an era of increasing subspecialization, underline the importance of viewing the "whole picture"...

..We attempted to evaluate parameters of patient awareness and disease perception in brucellosis and the ways they influence outcome...

..The importance of including the pathogen in the differential diagnosis of ENT patients, in assorted epidemiological settings, and the significance of the proper antibiotic selection are further discussed...

..The authors propose the use of a combination of doxycycline and ciprofloxacin for a period of 3 months, and report the successful use of such a combination in five patients with brucellosis and spondylitis...

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..The patient was diagnosed as suffering from brucellosis on the basis of a strongly positive serologic reaction and was treated with doxycycline, streptomycin, and a short course of corticosteroids, with a rapid rise in platelet number...

..Further workup on the mechanisms of motile Enterococci resistance to vancomycin could probably yield useful information in achieving new ways of facing resistance attributed to the more usual, and malignant Enterococci...

..We further discuss the context of pathophysiology of the arthritis in these patients, with an emphasis on the immunomodulatory properties of these two pathogens...

..We also discuss aspects of the respiratory pathology, radiological characteristics, coexisting complications, and aspects of treatment of respiratory brucellosis...

..Alternatively, modification of the acidic intracellular environment where Brucellae reside may allow for enhanced effectiveness of existing antibiotics...

..Pseudomonas fluorescens is 1 of the less virulent members of the Pseudomonadaceae family. The epidemiology of the infection and the difficulties in isolation and susceptibility assessment are further discussed...

..Awareness of this new global map of human brucellosis will allow for proper interventions from international public-health organisations...

..We therefore believe that gallbladder adenomyomatosis should be considered in the differential diagnosis of sustained fever with negative workup...

..Both cases of ascites were of an effusion type, with a predominantly lymphocytic cell count, and exhibited an excellent response to treatment with tetracycline and rifampicin...

..Characteristics and burden of primary bacteremia because of multidrug-resistant (MDR) gram-negative bacteria (GNB) in intensive care unit (ICU) patients remain understudied...

..Data on paratuberculosis incidence are scarce, and the existing ones are ambivalent regarding an even indirect correlation between CD and an infectious trigger...

..We sought to determine the liver histologic patterns present in a series of brucellosis patients and review the existing knowledge about liver involvement in this worldwide, prevalent zoonotic infection...

..For this reason, modern clinicians and researchers continue to be attracted to these 'lessons' from the past - lessons that remain extremely valuable...

..Free access to related research remains a controversial issue...

..Despite the continuing high incidence of brucellosis, vague aspects of pathophysiology, diagnosis, and treatment continue to exist, particularly with regard to the ability of Brucella species to survive inside the host...

..The finding of high levels of D-dimers in AOSD needs further studies...

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..Large multicentre studies may further define the optimal interventions in severe leptospirosis as well as possible variations in the pathogenic and clinical parameters of respiratory leptospirosis...

..We evaluated the existing medical data on infectious risks and related preventive and treatment data for cirrhotic patients...

..However, what is missing is a site that will continuously update health professionals who deal with zoonoses in all their medical, veterinary and public health aspects...

..Although genetic linkage studies have demonstrated a potential genetic predisposition to temporal arteritis, this is one of the rare multiple occurrences of temporal arteritis in a family reported in the literature...

..The World Wide Web, an increasingly popular means of dissemination of health-related information, can serve continuing medical practitioner awareness and enhance public health literacy...

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..This review summarizes the cellular immune responses in brucellosis, based on data derived exclusively from human cells or cell lines...

..In addition, there are no data regarding the effect of prophylactic practices involving antibiotic administration in morbidity and mortality...

..To identify and evaluate electronic internal medicine educational sources and develop a list of major Web sites for interested practitioners...

..Although numerous drugs have been associated with eosinophilia and eosinophilic pleural effusion, the spectrum may actually be wider than is commonly thought and may include such unrecognized agents as diltiazem...

..The all-cause hospital mortality was 16.7%, and may have been influenced by relatively early diagnosis, indicating the need for heightened clinical suspicion in Europe...

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..However, during the most recent decade, there has been a paucity of human cases despite the detection of hantavirus in rodents of this area...

..The combined use of tissue transglutaminase and deamidated gliadin peptide antibodies seems to be a very useful tool for celiac disease diagnosis. Moreover, antibodies to deamidated gliadin peptides can be helpful in disease follow-up...

..infection, which is different than in animal models. Here we review Brucella spp. virulence factors and how they control bacterial trafficking within the host cell...