Research Topics
Species | A D AnastasilakisSummaryAffiliation: Hippocration General Hospital Country: Greece Publications
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Detail Information
Publications
Acute phase response following intravenous zoledronate in postmenopausal women with low bone massAthanasios D Anastasilakis
Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece
Bone 50:1130-4. 2012..Serum 25(OH)D concentrations decrease significantly after the infusion, possibly as part of the inflammatory response to ZOL...
Selenomethionine treatment in patients with autoimmune thyroiditis: a prospective, quasi-randomised trialA D Anastasilakis
Department of Endocrinology, 424 Military Hospital, Thessaloniki, Greece
Int J Clin Pract 66:378-83. 2012..To test whether selenium administration affects autoantibodies to thyroid peroxidase (anti-TPO) and thyroglobulin (anti-TG) titres in chronic autoimmune (Hashimoto's - HT) thyroiditis...
Role of wingless tail signaling pathway in osteoporosis: an update of current knowledgeAthanasios D Anastasilakis
Department of Endocrinology, 424 General Military Hospital, Second Medical Clinic, Medical School, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece
Curr Opin Endocrinol Diabetes Obes 18:383-8. 2011..This review summarizes the evidence published during the previous year on the emerging role of Wnt signaling alterations in the pathogenesis, diagnosis, and potential therapeutic approaches of osteoporosis...
Denosumab and bisphosphonates: rivals or potential "partners"? A "hybrid" molecule hypothesisAthanasios D Anastasilakis
Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece
Med Hypotheses 77:109-11. 2011....
A case report of subacute thyroiditis during pregnancy: difficulties in differential diagnosis and changes in cytokine levelsAthanasios D Anastasilakis
Department of Endocrinology, 424 Military Hospital, Thessaloniki, Greece
Gynecol Endocrinol 27:384-90. 2011..Thyroid dysfunction during pregnancy may result in both maternal and neonatal complications. Subacute thyroiditis (SAT) is an extremely rare cause of both hyper- and hypothyroidism in pregnant women...
The effect of teriparatide on serum Dickkopf-1 levels in postmenopausal women with established osteoporosisAthanasios D Anastasilakis
Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece
Clin Endocrinol (Oxf) 72:752-7. 2010..We aimed to evaluate serum levels of the Wnt-inhibitor Dickkopf-1 (Dkk-1) in postmenopausal women with established osteoporosis and their changes with teriparatide (TPTD - human recombinant PTH 1-34)...
Normochromic normocytic anemia in a postmenopausal woman with severe osteoporosis treated with intermittent parathyroid hormoneAthanasios D Anastasilakis
Department of Endocrinology, 424 Military Hospital, Thessaloniki, Greece
J Bone Miner Metab 28:108-10. 2010..Anemia was more pronounced with PTH 1-84 compared to PTH 1-34 and was reversed with each regimen discontinuation. We suggest monitoring of hematocrit and hemoglobin in PTH-treated patients, especially when PTH 1-84 is used...
Efficacy and safety of denosumab in postmenopausal women with osteopenia or osteoporosis: a systematic review and a meta-analysisA D Anastasilakis
Department of Endocrinology, 424 Military Hospital, Thessaloniki, Greece
Horm Metab Res 41:721-9. 2009..45 (1.15 to 17.14), p=0.03] were evident. In conclusion, although effective as an antiresorptive agent, denosumab has not yet proved its efficacy on fracture risk reduction while increased infection risk questions its safety...
Effect of strontium ranelate on lumbar spine bone mineral density in women with established osteoporosis previously treated with teriparatideA D Anastasilakis
Department of Endocrinology, 424 Military Hospital, Thessaloniki, Greece
Horm Metab Res 41:559-62. 2009..641, p=0.007) and SR treatment (r=0.539, p=0.026). In conclusion, our data suggest that SR following TPTD administration further increases BMD and could represent an effective sequential treatment...
Acute and chronic effect of teriparatide on glucose metabolism in women with established osteoporosisA Anastasilakis
Department of Endocrinology, Hippocration General Hospital, Thessaloniki, Greece
Exp Clin Endocrinol Diabetes 115:108-11. 2007..TPTD seems to have an acute, subclinical adverse impact on stimulated glucose levels, possibly due to insulin resistance. This impact tends to subside when TPTD is continued on a chronic basis...
No difference between strontium ranelate (SR) and calcium/vitamin D on bone turnover markers in women with established osteoporosis previously treated with teriparatide: a randomized controlled trialAthanasios D Anastasilakis
Department of Endocrinology, Hippocration General Hospital, Thessaloniki, Greece
Clin Endocrinol (Oxf) 70:522-6. 2009..7 +/- 1.7 years) with established osteoporosis previously treated with TPTD 20 microg daily for 18 months were randomly assigned to receive either SR (SR group, n = 11) or calcium and vitamin D (control group, n = 11)...
Oral bisphosphonate adverse effects in 849 patients with metabolic bone diseasesAthanasios D Anastasilakis
Department of Endocrinology, Hippocration General Hospital, Thessaloniki, Greece
Hormones (Athens) 6:233-41. 2007..The aim of this study was to compare the adverse effects (AEs) of alendronate, etidronate and risedronate prescribed in a non-selected population, attending a single institution on an outpatient basis...
Effect of exogenous intermittent recombinant human PTH 1-34 administration and chronic endogenous parathyroid hormone excess on glucose homeostasis and insulin sensitivityA D Anastasilakis
Department of Endocrinology, Hippocration General Hospital, Thessaloniki, Greece
Horm Metab Res 40:702-7. 2008....
Serum osteoprotegerin and RANKL are not specifically altered in women with postmenopausal osteoporosis treated with teriparatide or risedronate: a randomized, controlled trialA D Anastasilakis
Department of Endocrinology, Hippocration General Hospital, Thessaloniki, Greece
Horm Metab Res 40:281-5. 2008....
Acute changes in serum osteoprotegerin and receptor activator for nuclear factor-kappaB ligand levels in women with established osteoporosis treated with teriparatideAthanasios D Anastasilakis
Department of Endocrinology, Hippocration General Hospital, 54642 Thessaloniki, Greece
Eur J Endocrinol 158:411-5. 2008....
Head-to-head comparison of risedronate vs. teriparatide on bone turnover markers in women with postmenopausal osteoporosis: a randomised trialA D Anastasilakis
Department of Endocrinology, Hippocration General Hospital, Thessaloniki, Greece
Int J Clin Pract 62:919-24. 2008..We aimed to compare the effect of risedronate (RIS) and teriparatide (TPTD) (recombinant human parathyroid hormone 1-34) on bone turnover markers in women with postmenopausal osteoporosis...
Zoledronic acid-induced transient hepatotoxicity in a patient effectively treated for Paget's disease of boneS A Polyzos
Second Medical Clinic, Medical School, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece
Osteoporos Int 22:363-7. 2011..Although the mechanism by which ZOL may cause liver damage is elusive, physicians should be aware of this possible adverse effect and ZOL cautiously administered in NAFLD patients...
Paget's disease of bone and calcium homeostasis: focus on bisphosphonate treatmentS A Polyzos
Second Medical Clinic, Medical School, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece
Exp Clin Endocrinol Diabetes 119:519-24. 2011..Secondary hyperparathyroidism may be a potentially detrimental condition for patients with Paget's disease of bone...
The effect of zoledronic acid on serum dickkopf-1, osteoprotegerin, and RANKL in patients with Paget's disease of boneS A Polyzos
Department of Endocrinology, Ippokration General Hospital, Thessaloniki, Greece
Horm Metab Res 41:846-50. 2009..Although both OPG and RANKL were increased in patients with PDB, ZOL had no effect on their serum levels. Serum DKK-1 was neither increased in patients with PDB nor related to OPG and RANKL, and was unaffected by ZOL...
Endogenous intact PTH is suppressed during Teriparatide (rhPTH 1-34) administration in postmenopausal women with established osteoporosisAthanasios D Anastasilakis
Department of Endocrinology, Hippocration General Hospital, Thessaloniki, Greece
Endocr J 55:613-6. 2008..The aim of this prospective trial was to evaluate the acute and chronic effects of TPTD in endogenous intact PTH (iPTH) levels in postmenopausal women with established osteoporosis...
A systematic review of cases reporting needle tract seeding following thyroid fine needle biopsyStergios A Polyzos
Second Medical Clinic, Medical School, Aristotle University of Thessaloniki, Ippokration Hospital, 546 42, Thessaloniki, Greece
World J Surg 34:844-51. 2010..In this review we tried to systematically record all reports of NTS after diagnostic thyroid FNB and provide useful hints to minimize the risk of NTS...
Alterations in serum thyroid-related constituents after thyroid fine-needle biopsy: a systematic reviewStergios A Polyzos
Second Medical Clinic, Medical School, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece
Thyroid 20:265-71. 2010....
Primary hyperparathyroidism and incidental multifocal metastatic papillary thyroid carcinoma in a manStergios A Polyzos
Second Medical Clinic, Ippokration Hospital, Aristotle University of Thessaloniki, Greece
Arq Bras Endocrinol Metabol 54:578-82. 2010..Given that there are no specific guidelines for the management of patients with synchronous PHPT and PTC, they should be managed like the cases of single PTC...
Systematic review of cases reporting blood extravasation-related complications after thyroid fine-needle biopsyStergios A Polyzos
Second Medical Clinic, Medical School, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece
J Otolaryngol Head Neck Surg 39:532-41. 2010..In this review, we tried to summarize all reported blood extravasation-related post-FNB complications (hemorrhage, hematomas, and secondary hemangiomas) and provide useful hints to avoid them...
Profound hypocalcemia following effective response to zoledronic acid treatment in a patient with juvenile Paget's diseaseStergios A Polyzos
Department of Endocrinology, Ippokration General Hospital, 13 Simou Lianidi, Thessaloniki, Greece
J Bone Miner Metab 28:706-12. 2010..We describe hereby, for the first time in the literature, the case of a patient with JPD who developed severe hypocalcemia and secondary hyperparathyroidism following effective treatment with ZOL...
Serum homocysteine, folate and vitamin B12 in patients with Paget's disease of bone: the effect of zoledronic acidStergios A Polyzos
Department of Endocrinology, Ippokration General Hospital, Thessaloniki, Greece
J Bone Miner Metab 28:314-9. 2010..Our data suggest that serum HCY levels are increased in patients with PDB. A single ZOL infusion results in a decrease in HCY levels that might represent another mechanism for the reduction of the activity of PDB achieved by ZOL...
Dual-energy X-ray absorptiometry and quantitative ultrasound in patients with Paget's disease of bone before and after treatment with zoledronic acid: association with serum bone markers and Dickkopf-1Stergios A Polyzos
Department of Endocrinology, Ippokration General Hospital, Thessaloniki, Greece
J Clin Densitom 13:190-6. 2010..Our data suggest that a single ZOL infusion significantly increases nonpagetic BMD 12 mo after treatment but has no effect on QUS parameters or DKK-1. Significant correlations were observed between QUS parameters and DKK-1 at baseline...
Clinical complications following thyroid fine-needle biopsy: a systematic reviewStergios A Polyzos
Second Medical Clinic, Medical School, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece
Clin Endocrinol (Oxf) 71:157-65. 2009..In this systematic review we tried to collect and summarize all reported clinical complications following diagnostic thyroid FNB, aiming to make physicians aware of possible complications and to provide preventive measures to avoid them...
Serum sclerostin levels positively correlate with lumbar spinal bone mineral density in postmenopausal women-the six-month effect of risedronate and teriparatideS A Polyzos
Second Medical Clinic, Medical School, Aristotle University of Thessaloniki, Ippokration Hospital, 13 Simou Lianidi, 551 34, Thessaloniki, Greece
Osteoporos Int 23:1171-6. 2012..Furthermore, serum sclerostin was increased after 6 months treatment with risedronate, whereas remained unchanged after 6 months teriparatide treatment...
RANKL inhibition for the management of patients with benign metabolic bone disordersAthanasios D Anastasilakis
Department of Endocrinology, 424 Military Hospital, Thessaloniki, Greece
Expert Opin Investig Drugs 18:1085-102. 2009....
