M E Falagas

..baumannii as well as the implementation of infection control measures that may help us in the control of the increasing problem of A. baumannii infections...

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..There has been a continuing controversy about whether infection with Acinetobacter baumannii increases morbidity and mortality independently of the effect of other confounding factors...

..We sought to review the available evidence regarding the effect of psychosocial factors on the survival of breast cancer patients...

..Our objective was to identify and describe the population-based health-promotion programs implemented in relation to the Athens 2004 Olympic and Para Olympic Games...

..In order to map the research production around the world we performed a bibliometric analysis in the above fields...

..We sought to provide the world medical community with a web portal that may be used as a clearinghouse providing the outlet for dissemination of high quality WWW educational products...

..The prevalence of hepatitis B virus infection in Greece has been decreasing over the last decades. However, recent epidemiological data are lacking...

..The objective of this study was to estimate the research productivity of different world regions in the field of Parasitology...

..Antimicrobial resistance is one of the most challenging issues in modern medicine...

..In this study, we analyzed the prevalence and predictors of tuberculin skin testing positivity in Hellenic Army recruits...

..Physicians house calls to patients have been declining in many countries of the world. The objective of this study was to describe the patterns of utilization of house call services provided by SOS doctors in the area of Attica, Greece...

..We aimed to review the literature regarding the epidemiology of constipation in Europe and Oceania and the associated prevalence/risk factors...

..Thus, the emergence of infections due to carbapenem-resistant K. pneumoniae (CRKp) is a major public health concern...

..Our impression was that several common chronic diseases responsible for many DALYs are frequently under-diagnosed...

..Google Scholar, as for the Web in general, can help in the retrieval of even the most obscure information but its use is marred by inadequate, less often updated, citation information...

..Seasonal increases in the mortality rate have been associated with excessively cold or hot weather. We evaluated monthly patterns of mortality in selected countries...

..In the era of the World Wide Web we sought to examine whether the use of PubMed and Google can help physicians to improve their diagnostic skills...

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..baumannii, P. aeruginosa, or K. pneumoniae) is polymyxin-only-susceptible is close to that (50%) used in our model (based on the individual hospital data)...

..To evaluate whether the use of high doses of quinolones may reduce the development of antimicrobial resistance...

..However, the existence of the identified case reports suggests that clinicians should include coil-related infection in the differential diagnosis of patients with fever after this procedure...

..The role of sex hormones in the regulation of the immune system may also contribute to the reported sex differences in the incidence and severity of the various types of RTIs, especially in adolescents and adults...

..Furthermore, it is a bactericidal antibiotic, a factor that is frequently considered in the choice of treatment of patients with bacteraemia and endocarditis...

..baumannii isolates resistant to imipenem from patients hospitalised in intensive care units, medical wards and surgical wards during the study period from 0% to 91%, 8% to 71%, and 5% to 71%, respectively...

..The data suggest that Acinetobacter infections are a growing threat affecting a considerable proportion of critically ill patients, especially in Asia and Europe...

..The potential need for re-evaluation of guidelines on surgical antimicrobial prophylaxis (AMP) in an era of advancing antimicrobial resistance is a matter of a considerable controversy...

..Many interventions have been employed in order to limit the incidence of these infections or to treat them when the prophylactic measures fail...

..Editors and publishers should strive for quality through fair and thoughtful selection of papers forwarded for peer review and editorial comments that enhance the quality and scientific accuracy of a manuscript...

..To evaluate the effectiveness and safety of short-course antibiotic treatment of group A beta-hemolytic streptococcal (GAS) tonsillopharyngitis...

..001), shock (p = 0.001), acute respiratory distress syndrome (p = 0.001), influenza like symptoms (p = 0.008), disseminated intravascular coagulation (p = 0.042) and rash (p = 0.04) were the factors associated with death...

..We suggest that antibiotics should be reserved for carefully selected patients with a higher probability for bacterial disease...

..We sought to evaluate the trends in the methodological quality of randomized controlled trials in various medical fields...

..Reports of patients with polymyxin-only susceptible gram-negative nosocomial pneumonia treated with inhaled, but without concurrent intravenous, colistin are rare...

..Shortened treatment, particularly for patients without severe disease and complicating factors, might lead to fewer adverse events, better patient compliance, lower rates of resistance development and fewer costs...

..The available evidence, mainly from old case series, suggests that systemic colistin is an effective and acceptably safe option for the treatment of children without CF who have MDR Gram-negative infections...

..maltophilia infections; the majority of them refer to patients with some kind of comorbidity. Physicians should be aware that S. maltophilia infections are not restricted to hospitalized patients...

..The awareness of this association may facilitate preventive public health strategies. [corrected]..

..Thus, we sought to perform a systematic review of the evidence regarding the association of SES with adherence to treatment of patients with HIV/AIDS...

..Statins are currently used for hyperlipidaemia control and considered useful for protection from cardiovascular events. In addition, there is increasing evidence for the potential use of statins in preventing and treating infections...

..Public health authorities should be aware of this issue and consider appropriate preventive and control measures...

..Tigecycline and polymyxins have substantial antimicrobial activity against ESBL-producing Enterobacteriaceae, and, along with fosfomycin, merit further evaluation...

..A more consistent use of matching with the specific type of surgical procedure may help in increasing the internal validity of a case-control study in this field of clinical research...

..with data to answer the following simple question: What proportion of publications in the various scientific fields is published in journals with impact factor above the median and mean values of the distribution of journal impact factor?..

..Such trials should initially employ selected strains of probiotics for which there are preliminary data regarding their effectiveness and lack of common or serious toxicity...

..The aim of this study was to evaluate the comparative effectiveness and safety of short (5 days) and long (7 or 10 days) duration antimicrobial treatment of patients with acute exacerbations of chronic bronchitis (AECB)...

..The advancing antimicrobial drug resistance in Gram-positive cocci complicates the selection of appropriate therapy. The re-evaluation of older antibiotics may prove useful in expanding relevant therapeutic options...

..Although not consistently reported, an association of both ends of the BMI distribution with worse outcome of infections is plausible and merits further investigation...

..We aimed to evaluate the power of such studies to provide clinically and statistically significant conclusions with regard to mortality differences...

..Group B beta-hemolytic streptococcus (Streptococcus agalactiae) has been traditionally considered a major pathogen in neonates and pregnant women. However, there is accumulating concern about its significance in non-pregnant adults too...

..In addition, symptoms from the lower urinary tract may not be prominent in this population...

..Surprisingly, the pathophysiological and practical implications of their co-existence have received little attention...

..The addition of an aminoglycoside to a beta-lactam for the treatment of patients with infective endocarditis has been supported by data from laboratory and animal studies...

..To evaluate the effect of inappropriate empirical antimicrobial treatment on the mortality of patients with Acinetobacter baumannii bacteraemia...

..POS gram-negative pathogens represent a major threat for hospitalized patients. Colistin appears to be an effective and safe treatment, even in patients with severe underlying diseases...

..Fosfomycin was inactive against the 166 enterococcal isolates tested. This old antibiotic may deserve consideration for further studies and use in clinical practice, especially for S. aureus (including MRSA) infections...

..We sought to study the trends of the antimicrobial resistance of blood isolates in patients from a rural population hospitalized in a tertiary hospital in a small city in Greece...

..This study was undertaken to evaluate the frequency, characteristics, and risk factors of microbiologically documented nosocomial infections after off-pump coronary artery bypass grafting...

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..Appropriately designed and powered clinical trials are warranted to investigate the effectiveness and safety of the combined administration of statins and OM3FA for the prevention and treatment of sepsis...

..Several studies suggest that neuraminidase inhibitors (NIs) can reduce the duration of influenza symptoms. However, data regarding their effectiveness in reducing influenza complications are scarce...

..We aimed to evaluate the potential inaccuracies in administering the desired dose of drugs with teaspoons and tablespoons...

..Intra-abdominal infections result in substantial morbidity and mortality. Fluoroquinolones are among the various regimens that are used for the treatment of these infections...

..Cystitis is a common infection. The alarmingly high resistance rates exhibited by contemporary uropathogens necessitate the re-evaluation of old antibiotics...

..Although data from comparative trials are required to draw definitive conclusions, the available evidence suggests that the administration of heparin should be considered early in the management of patients with septic thrombophlebitis...

..No difference in mortality was noted. Caspofungin was associated with better clinical outcomes (higher cure and fewer adverse effects) than amphotericin B in the treatment of patients with fungal infections...

..Morganella morganii is a commensal Gram-negative bacillus of the intestinal tract of humans and other mammals and reptiles. Few reports exist in the literature regarding infections caused by this organism...

..To compare the effectiveness and safety of fluoroquinolones with beta-lactams in the treatment of patients with skin and soft tissue infections (SSTIs)...

..This was associated with control of a nosocomial outbreak in two studies, eradication of persistent environmental contamination with MRSA and decrease in C. difficile infection in each of the remaining two studies...

..The findings of the largest cohort study to date on i.v. colistin show that colistin is a valuable antibiotic with acceptable nephrotoxicity and considerable effectiveness that depends on the daily dosage and infection site...

..In patients with Pseudomonas aeruginosa pneumonia, carbapenems are associated with worse outcomes than the comparators...

..aureus (MSSA) community-acquired pneumonia (CAP) producing the Panton-Valentine leukocidin (PVL)...

..Intravenous fosfomycin may be a beneficial and safe adjunctive treatment in the management of life-threatening ICU-acquired infections caused by carbapenem-resistant K. pneumoniae...

..ICU and total in-hospital mortality were 40% and 66.7%, respectively. Candidaemia-related mortality was 20%. Candidaemia treatment failure was the only variable associated with in-hospital mortality (p 0.008)...

..Thus, although the available results concerning the effectiveness of the administration of lactobacilli for the treatment of BV are mostly positive, it cannot yet be concluded definitively that probiotics are useful for this purpose...

..pneumoniae and, secondly, P. aeruginosa...

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..Clinicians who, according to the survey, demonstrated that they know the diagnostic performance characteristics of cultures more often obtain one culture from the CVC and one from the PV (73.9% vs. 61.7%, p 0.037)...

..We sought to further investigate this issue in general and internal medicine journals...

..The evaluation of the currently available published evidence contributes to the clarification of the epidemiological features of pandemic 2009 A(H1N1) influenza, which is useful in terms of the individual and public health perspectives...

..Systematic review...

..in its spectrum when this organism is isolated from patients with such infections...

..This could potentially impede a central step in the pathogenesis of nosocomial infections...

..The results of this preliminary study suggest that aerosolized colistin was effective in reducing quickly the microbial counts and eliminating microbial growth of Pseudomonas aeruginosa by the sixth day of use in all studied patients...

..Ertapenem is a new member of the carbapenem class of antibiotics, with a favourable pharmacokinetic profile, but a narrower spectrum of antimicrobial activity, compared with older representatives of this class...

..21/57 (36.8%) deaths, p 0.007), even after adjusting for the variables for which significant differences were found...

..Patients with Waldenström's macroglobulinemia may manifest several types of skin lesions. We present our experience with a patient with the disease that adds to the literature on the topic...

..To perform a systematic review of the literature to assess the possible effect that psychosocial variables may have on the susceptibility and/or outcome of acute respiratory tract infections (ARTIs)...

..In contrast, this coexistence is rare in NIC critically ill patients with Candida bloodstream infections. A high mortality was noted in both IC and NIC critically ill patients with candidemia...

..There is an ongoing discussion in the scientific community that even the leading scientific journals publish mainly research that is produced in the countries where these journals are based...

..To compare the effectiveness and safety of clindamycin/aminoglycoside with broad-spectrum beta-lactam monotherapy in patients with intra-abdominal infections by performing a meta-analysis of randomized controlled trials (RCTs)...

..The available evidence supports that the local administration of polymyxins into the respiratory tract for the prevention and treatment of multidrug-resistant (MDR) Gram-negative bacterial infections deserves further investigation...

..baumannii and P. aeruginosa suggests that a separate outbreak investigation should be performed in each hospital setting. The development of innovative control strategies is needed in order to limit the spread of these pathogens...

..Pregnant women represented 7·4-9·1% and 7·1-9·1% of unselected laboratory-confirmed cases and of those admitted to ICUs, respectively. Obesity and morbid obesity were more commonly reported as the level of healthcare increased...