Research Topics
| Anagnostis ValotisSummaryCountry: Germany Publications
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Detail Information
Publications
Human receptor kinetics, tissue binding affinity, and stability of mometasone furoateAnagnostis Valotis
, , Am Hubland, , Germany
J Pharm Sci 93:1337-50. 2004..The binding affinity of MF to human lung tissue was low compared to FP due to fast redistribution from tissue into plasma. These molecular pharmacological properties are in accordance with clinical data...
Significant receptor affinities of metabolites and a degradation product of mometasone furoateAnagnostis Valotis
Institut für Pharmazie und Lebensmittelchemie, Bayerische Julius Maximilians Universität, Wurzburg, Germany
Respir Res 5:7. 2004..Hence, we provide data that might contribute to the understanding of the pharmacokinetics as well as the clinical effects of MF...
Numerical modelling of label-structured cell population growth using CFSE distribution dataTatyana Luzyanina
Institute of Numerical Mathematics, RAS, Moscow, Russia
Theor Biol Med Model 4:26. 2007..The quantitative interpretation and understanding of such heterogenous cell population data requires the development of distributed parameter mathematical models and computational techniques for data assimilation...
Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoateAnagnostis Valotis
Universitat Wurzburg, Institut für Pharmazie und Lebensmittelchemie, Wurzburg, Germany
Respir Res 8:54. 2007..These advantageous binding attributes may contribute to a highly efficacious profile for FF as a topical treatment for inflammatory disorders of the respiratory tract...
Monitoring the initial pulmonary absorption of two different beclomethasone dipropionate aerosols employing a human lung reperfusion modelMatthias Freiwald
Institut für Pharmazie und Lebensmittelchemie, Bayerische Julius Maximilians Universität, Wurzburg, Germany
Respir Res 6:21. 2005..Our objective was to monitor and compare the combined process of drug particle dissolution, pro-drug activation and time course of initial distribution from human lung tissue into plasma for two different glucocorticoid formulations...
Human intestinal hydrolysis of phenol glycosides - a study with quercetin and p-nitrophenol glycosides using ileostomy fluidBastian Knaup
Food Chemistry, University of Wuerzburg, Wuerzburg, Germany
Mol Nutr Food Res 51:1423-9. 2007..09 micromol/h) to the alpha-L-rhamnopyranoside (0.06 micromol/h). These results demonstrate that the human ileal hydrolysis of phenol glycosides depends on the sugar and the aglycon structure as well as the microflora...
