Research Topics
| Heike ZeitlerSummaryAffiliation: University of Bonn Country: Germany Publications
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Detail Information
Publications
Multiple benign symmetric lipomatosis--a differential diagnosis of obesity: is there a rationale for fibrate treatment?Zeitler Heike
Centre of Extracorporeal Treatment and Lipid Disorders, Medical Policlinic, Bonn, Germany
Obes Surg 18:240-2. 2008..Fibrates, peroxisome proliferator-activated receptor alpha agonists, are pleiotropic hypolipidemic drugs and might have worked by suppression of protein expressions involved in the architecture of BAT keeping it in a quiescent state...- Immunoadsorption in the treatment of acquired haemophiliaHeike Zeitler
Internal Medical Clinic I of the University of Bonn, Centre of Extracorporeal Therapy and Autoimmunity, Germany
Atheroscler Suppl 10:122-5. 2009..However, the severity of bleeding, and therefore the cost-effectiveness of the approach, needs to be considered when initiating this treatment protocol... - The relevance of the bleeding severity in the treatment of acquired haemophilia - an update of a single-centre experience with 67 patientsH Zeitler
Internal Medical Clinic I of the University of Bonn, Centre of Extracorporeal Therapy and Autoimmunity CETA, Bonn, Germany
Haemophilia 16:95-101. 2010..Treatment procedures should be adapted to bleeding severity and inhibitor titres. Under these conditions, AH is a potentially curable autoimmune disorder with an excellent prognosis... - Multiple benign symmetric lipomatosis--a differential diagnosis of obesity. Is there a rationale for fibrate treatment?Heike Zeitler
Centre of Extracorporeal Treatment and Lipid Disorders, Bonn, Germany
Obes Surg 18:1354-6. 2008.... - Treatment of acquired hemophilia by the Bonn-Malmo Protocol: documentation of an in vivo immunomodulating conceptHeike Zeitler
Medical Policlinic, University of Bonn, Wilhelmstrasse 35 37, 53111 Bonn, Germany
Blood 105:2287-93. 2005..Long-term follow-up (7 months-7 years) showed an overall response rate of 88% for complete remission (CR). When cancer patients were excluded, the CR rate was 97%... - Long-term effects of a multimodal approach including immunoadsorption for the treatment of myasthenic crisisHeike Zeitler
Medical Policlinic, University of Bonn, Bonn, Germany
Artif Organs 30:597-605. 2006..4 years. No fatalities due to MC occurred. The results demonstrate that our protocol is a potent therapeutic approach in the treatment of MC... - Protective effects of taurine on endothelial cells impaired by high glucose and oxidized low density lipoproteinsGudrun Ulrich-Merzenich
Medical Policlinic of the Friedrich Wilhelm University of Bonn, Wilhelmstrasse 35 37, 53111 Bonn, Germany
Eur J Nutr 46:431-8. 2007..Endothelial dysfunction, common to diabetes and cardiovascular diseases, is an early step in the development of atherosclerosis and diabetic angiopathies. Deficiencies of taurine have been related to diabetes and cardiovascular diseases... - Vitamin C promotes human endothelial cell growth via the ERK-signaling pathwayGudrun Ulrich-Merzenich
Medical Policlinic of the Rheinische, Friedrich Wilhelms University of Bonn, Wilhelmstr 35 37 53111 Bonn, Germany
Eur J Nutr 46:87-94. 2007..Large primary prevention trials failed to confirm this. Mechanistic studies may contribute to resolve this discrepancy... - Genetic markers in acquired haemophiliaJ Oldenburg
Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany
Haemophilia 16:41-5. 2010..17). This observation was mainly because of a higher frequency of the CTLA-4 + 49 G allele in female patients. These findings suggest that immune response genes may contribute to the development of anti-factor VIII autoantibodies in AH... - [The modified Bonn Malmö protocol (MBMP) in the treatment of acquired haemophilia A]H Zeitler
Medizinische Poliklinik der Universitat Bonn
Dtsch Med Wochenschr 131:141-7. 2006..Aim of an optimal treatment strategy should be to control bleedings by a rapid and safe elimination of the inhibitor and reinducing long-term immune tolerance... - New perspectives for synergy research with the "omic"-technologiesG Ulrich-Merzenich
Medical Policlinic of the Rheinische Friedrich Wilhelms University of Bonn, Wilhelmstr 35 37, D 53111 Bonn, Germany
Phytomedicine 16:495-508. 2009.... - Drug development from natural products: exploiting synergistic effectsGudrun Ulrich-Merzenich
Medical Policlinic of the Rheinische Friedrich Wilhelms University of Bonn, Wilhelmstr 35 37, D 53111 Bonn, Germany
Indian J Exp Biol 48:208-19. 2010.... - Application of the "-Omic-" technologies in phytomedicineG Ulrich-Merzenich
Medical Policlinic of Rheinische Friedrich Wilhelms University of Bonn, Wilhelmstr 35 37, D 53111 Bonn, Germany
Phytomedicine 14:70-82. 2007..The application of the "-omic-" technologies may lead to a change of paradigms towards the application of complex mixtures in medicine and open the new field of phytogenomics, -proteomics and -metabolomics... - Synergy research: vitamins and secondary plant components in the maintenance of the redox-homeostasis and in cell signalingGudrun Ulrich-Merzenich
Medizinische Poliklinik der Rheinischen Friedrich Wilhelms Universität Bonn, Bonn, Germany
Phytomedicine 16:2-16. 2009..Their relevance in the treatment of various diseases is discussed in the context of a multitarget therapy with nutraceuticals and phytotherapeutic drugs... - Increased frequency of the CTLA-4 49 A/G polymorphism in patients with acquired haemophilia A compared to healthy controlsA Pavlova
Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany
Haemophilia 14:355-60. 2008..In conclusion, on the background of the CTLA-4 gene polymorphism, further genetic and/or environmental factors might contribute to and finally trigger the clinical manifestation of AH...