Stefan Wilop

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. ncbi Array-based DNA methylation profiling in acute myeloid leukaemia
    Stefan Wilop
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Pauwelsstrasse 30, Aachen, Germany
    Br J Haematol 155:65-72. 2011
  2. ncbi Correlation of C-reactive protein with survival and radiographic response to first-line platinum-based chemotherapy in advanced non-small cell lung cancer
    Stefan Wilop
    Medizinische Klinik IV, Universitatsklinikum Aachen, RWTH Aachen, Germany
    Onkologie 31:665-70. 2008
  3. ncbi Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer undergoing first-line platinum-based chemotherapy
    Stefan Wilop
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    J Cancer Res Clin Oncol 135:1429-35. 2009
  4. ncbi Sequence of administration and methylation of SOCS3 may govern response to gemtuzumab ozogamicin in combination with conventional chemotherapy in patients with refractory or relapsed acute myelogenous leukemia (AML)
    Iris Middeldorf
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Pauwelsstrasse 30, Aachen, Germany
    Am J Hematol 85:477-81. 2010
  5. ncbi Antineoplastic chemotherapy in cancer patients with methicillin-resistant Staphylococcus aureus (MRSA)
    Martina Crysandt
    Medizinische Klinik IV, Universitatsklinikum, RWTH Aachen, Germany
    Onkologie 33:598-603. 2010
  6. ncbi Methylation-associated dysregulation of the suppressor of cytokine signaling-3 gene in multiple myeloma
    Stefan Wilop
    Medizinische Klinik IV, Universitätsklinikum Aachen RWTH Aachen, Germany
    Epigenetics 6:1047-52. 2011
  7. ncbi Aberrant DNA methylation of the transcription factor C/EBPalpha in acute myelogenous leukemia
    Edgar Jost
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    Leuk Res 33:443-9. 2009
  8. ncbi CpG island methylation patterns in chronic lymphocytic leukemia
    Barbara Seeliger
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Aachen, Germany
    Leuk Lymphoma 50:419-26. 2009
  9. ncbi Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia
    Reyad Dada
    Medizinische Klinik IV, Universitatsklinikum Aachen, RWTH Aachen University, Aachen, Germany
    Acta Haematol 122:216-20. 2009
  10. ncbi Cisplatin as single-agent chemotherapy in patients with liver dysfunction due to metastases
    Stefan Wilop
    Medizinische Klinik IV, Universitatsklinikum Aachen, RWTH Aachen, Germany
    Onkologie 32:400-4. 2009

Collaborators

Detail Information

Publications12

  1. ncbi Array-based DNA methylation profiling in acute myeloid leukaemia
    Stefan Wilop
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Pauwelsstrasse 30, Aachen, Germany
    Br J Haematol 155:65-72. 2011
    ..Array-based methylation analysis determined distinct methylation profiles for non-malignant controls and AML samples with specific chromosomal aberrations and can identify target genes for further evaluation...
  2. ncbi Correlation of C-reactive protein with survival and radiographic response to first-line platinum-based chemotherapy in advanced non-small cell lung cancer
    Stefan Wilop
    Medizinische Klinik IV, Universitatsklinikum Aachen, RWTH Aachen, Germany
    Onkologie 31:665-70. 2008
    ..This study was conducted to assess the prognostic role of regular measurements of C-reactive protein (CRP) in patients with advanced-stage non-small cell lung cancer (NSCLC) during platinum-based first-line therapy...
  3. ncbi Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer undergoing first-line platinum-based chemotherapy
    Stefan Wilop
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    J Cancer Res Clin Oncol 135:1429-35. 2009
    ..Until now, very limited clinical data for this antiangiogenic effect exists for combinations with antineoplastic chemotherapy...
  4. ncbi Sequence of administration and methylation of SOCS3 may govern response to gemtuzumab ozogamicin in combination with conventional chemotherapy in patients with refractory or relapsed acute myelogenous leukemia (AML)
    Iris Middeldorf
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Pauwelsstrasse 30, Aachen, Germany
    Am J Hematol 85:477-81. 2010
    ..The potential role of SOCS3 hypermethylation as a biomarker should be further investigated in patients undergoing GO containing therapies...
  5. ncbi Antineoplastic chemotherapy in cancer patients with methicillin-resistant Staphylococcus aureus (MRSA)
    Martina Crysandt
    Medizinische Klinik IV, Universitatsklinikum, RWTH Aachen, Germany
    Onkologie 33:598-603. 2010
    ..There are presently no guidelines with appropriate provisions for antineoplastic chemotherapy in cancer patients with MRSA colonization or infection...
  6. ncbi Methylation-associated dysregulation of the suppressor of cytokine signaling-3 gene in multiple myeloma
    Stefan Wilop
    Medizinische Klinik IV, Universitätsklinikum Aachen RWTH Aachen, Germany
    Epigenetics 6:1047-52. 2011
    ..Epigenetic dysregulation of the SOCS3 gene may interfere with the cellular response to the complex cytokine network thus supporting survival and expansion of MM cells...
  7. ncbi Aberrant DNA methylation of the transcription factor C/EBPalpha in acute myelogenous leukemia
    Edgar Jost
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    Leuk Res 33:443-9. 2009
    ..Our results provide further evidence for epigenetic dysregulation of C/EBPalpha in AML...
  8. ncbi CpG island methylation patterns in chronic lymphocytic leukemia
    Barbara Seeliger
    Medizinische Klinik IV, Universitaetsklinikum Aachen, RWTH Aachen, Aachen, Germany
    Leuk Lymphoma 50:419-26. 2009
    ..Epigenetic disturbances may be involved in the pathogenesis of CLL and thus may provide a molecular rationale for therapeutic approaches...
  9. ncbi Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia
    Reyad Dada
    Medizinische Klinik IV, Universitatsklinikum Aachen, RWTH Aachen University, Aachen, Germany
    Acta Haematol 122:216-20. 2009
    ..Clinicians should be aware of unusual presentations of ALL and difficulties for the application of chemotherapy in patients with liver failure...
  10. ncbi Cisplatin as single-agent chemotherapy in patients with liver dysfunction due to metastases
    Stefan Wilop
    Medizinische Klinik IV, Universitatsklinikum Aachen, RWTH Aachen, Germany
    Onkologie 32:400-4. 2009
    ..The toxicity and efficacy of cytotoxic drugs are often unpredictable due to altered drug activation or inactivation and excretion. Therefore, numerous chemotherapeutic agents should not be administered to patients with liver failure...
  11. ncbi Rituximab-associated changes in platelet count in patients with non-Hodgkin lymphoma
    Stefan Wilop
    Medizinische Klinik IV, Universitaetsklinikum Aachen, Aachen, Germany
    Leuk Lymphoma 49:2116-24. 2008
    ..In conclusion, a decline in platelet count after administration of rituximab was observed in patients with NHL, mainly those with pre-existing thrombocytopenia...
  12. ncbi Clinical implications of aberrant DNA methylation patterns in acute myelogenous leukemia
    Oliver Galm
    Medizinische Klinik IV, Universitatsklinikum Aachen, Rheinisch Westfälische Technische Hochschule Aachen, Aachen, Germany
    Ann Hematol 84:39-46. 2005
    ..The growing knowledge of the role of epigenetics in the aberrant silencing of cancer-related genes provides a rationale and molecular basis for targeted therapeutic approaches with demethylating agents in AML...