Research Topics
| Achim TreschSummaryAffiliation: University of Mainz Country: Germany Publications
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Detail Information
Publications
Discrimination of direct and indirect interactions in a network of regulatory effectsAchim Tresch
Institute for Medical Biometry, Epidemiology and Informatics, Mainz, Germany
J Comput Biol 14:1217-28. 2007..An efficient algorithm for the computation of the minimal graph is given, whose time complexity is cubic in the number of vertices of the graph. Finally, we demonstrate the utility of our method in a simulation study...
Structure learning in Nested Effects ModelsAchim Tresch
Johannes Gutenberg University Mainz
Stat Appl Genet Mol Biol 7:Article9. 2008..Third, we show that the new formulation of the likelihood allows efficiency in traversing model space. Fourth, we incorporate prior knowledge and an automated variable selection criterion to decrease the influence of noise in the data...
Intraoperative monitoring of cerebral microcirculation and oxygenation--a feasibility study using a novel photo-spectrometric laser-Doppler flowmetryKlaus Ulrich Klein
Department of Anesthesiology, University Hospital Medical Center, Johannes Gutenberg University, Mainz, Germany
J Neurosurg Anesthesiol 22:38-45. 2010..CO2 vasoreactivity during 2 different propofol concentrations was used to investigate changes of capillary venous cerebral blood flow (rvCBF), oxygen saturation (srvO2), and hemoglobin concentration (rvHb) during craniotomy...
A high oocyte yield for intracytoplasmic sperm injection treatment is associated with an increased chromosome error rateThomas Haaf
Institute for Human Genetics, Epidemiology and Informatics, Johannes Gutenberg University Mainz, Mainz, Germany
Fertil Steril 91:733-8. 2009..To compare the chromosome error rate among oocytes from stimulated ovaries after retrieval of 1-5 oocytes, 6-10 oocytes, and >10 oocytes...
The effects of arterial carbon dioxide partial pressure and sevoflurane on capillary venous cerebral blood flow and oxygen saturation during craniotomyKlaus Ulrich Klein
Department of Anesthesiology, Johannes Gutenberg University, Langenbeckstrasse 1, 55131 Mainz, Germany
Anesth Analg 109:199-204. 2009....
Outcome of intracytoplasmic sperm injection with and without polar body diagnosis of oocytesThomas Haaf
Institute for Human Genetics, Johannes Gutenberg University, Langenbeckstrasse 1, Bldg 601, 55131 Mainz, Germany
Fertil Steril 93:405-15. 2010..To compare the reproductive outcome of women undergoing intracytoplasmic sperm injection (ICSI) with or without polar body diagnosis of oocytes...
Assessment of postischemic neurogenesis in rats with cerebral ischemia and propofol anesthesiaIrina Lasarzik
Klinik fur Anasthesiologie, Johannes Gutenberg Universitat, Mainz, Germany
Anesthesiology 110:529-37. 2009..The effects of propofol on neurogenesis are unknown and, therefore, the object of this study...
Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeresAndreas May
Institute for Human Genetics, Johannes Gutenberg University Mainz, 55101 Mainz, Germany
Biol Reprod 80:194-202. 2009..Immunolocalization of DNMT3A, MBD3, APEX1, and LIG3 in most or all nuclei of 40-60-cell embryos is a good indicator of functional activity of genes that are activated by the 16-cell stage...
Analyzing gene perturbation screens with nested effects models in R and bioconductorHolger Frohlich
German Cancer Research Center, INF 580, 69120 Heidelberg, Germany
Bioinformatics 24:2549-50. 2008..The methods we present summarize the current state-of-the-art in NEMs. AVAILABILITY: Our software is written in the R language and freely avail-able via the Bioconductor project at http://www.bioconductor.org...
Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancerAndreas Buness
German Cancer Research Center DKFZ, Department of Molecular Genome Analysis, 69120 Heidelberg, Germany
Bioinformatics 23:2273-80. 2007..Such patterns have been found to be associated with chromosomal aberrations and clinical parameters like tumor grading and thus can be useful for risk stratification or therapy...
