Michael Strupp

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi Incidence of post-lumbar puncture syndrome reduced by reinserting the stylet: a randomized prospective study of 600 patients
    M Strupp
    Department of Neurology, Ludwig Maximilians University of Munich, Klinikum Grosshadern, Germany
    J Neurol 245:589-92. 1998
  2. ncbi Methylprednisolone, valacyclovir, or the combination for vestibular neuritis
    Michael Strupp
    Department of Neurology, University of Munich, Munich, Germany
    N Engl J Med 351:354-61. 2004
  3. ncbi Eye movements and balance
    Michael Strupp
    Department of Neurology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Ann N Y Acad Sci 1004:352-8. 2003
  4. ncbi Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine
    M Strupp
    Department of Neurology, University of Munich, Germany
    Neurology 62:1623-5. 2004
  5. ncbi [The most common form of dizziness in middle age: phobic postural vertigo]
    M Strupp
    Neurologische Klinik der Universität München, Klinikum Grosshadern, Munich
    Nervenarzt 74:911-4. 2003
  6. ncbi Anterior canal failure: ocular torsion without perceptual tilt due to preserved otolith function
    M Strupp
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    J Neurol Neurosurg Psychiatry 74:1336-8. 2003
  7. ncbi "Atraumatic" Sprotte needle reduces the incidence of post-lumbar puncture headaches
    M Strupp
    Department of Neurology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Neurology 57:2310-2. 2001
  8. ncbi ["Inner perilymph fistula" of the anterior semicircular canal. A new disease picture with recurrent attacks of vertigo]
    M Strupp
    Neurologische Klinik, Universitätsklinikum Grosshadern, Ludwig Maximilians Universitat Munchen
    Nervenarzt 71:138-42. 2000
  9. ncbi Acute vestibulopathy
    M Strupp
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Curr Opin Neurol 14:11-20. 2001
  10. ncbi Exercise and drug therapy alter recovery from labyrinth lesion in humans
    M Strupp
    Department of Neurology, University of Munich, Klinikum Grosshadern, Germany
    Ann N Y Acad Sci 942:79-94. 2001

Detail Information

Publications91

  1. ncbi Incidence of post-lumbar puncture syndrome reduced by reinserting the stylet: a randomized prospective study of 600 patients
    M Strupp
    Department of Neurology, Ludwig Maximilians University of Munich, Klinikum Grosshadern, Germany
    J Neurol 245:589-92. 1998
    ..This significant difference (16.3 vs 5.0%, P < 0.005, chi square test) supports our hypothesis. On the basis of our results, we recommend reinserting the stylet before removing the needle in order to reduce the incidence of PLPS...
  2. ncbi Methylprednisolone, valacyclovir, or the combination for vestibular neuritis
    Michael Strupp
    Department of Neurology, University of Munich, Munich, Germany
    N Engl J Med 351:354-61. 2004
    ..Its assumed cause is a reactivation of herpes simplex virus type 1 infection. Therefore, corticosteroids, antiviral agents, or a combination of the two might improve the outcome in patients with vestibular neuritis...
  3. ncbi Eye movements and balance
    Michael Strupp
    Department of Neurology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Ann N Y Acad Sci 1004:352-8. 2003
  4. ncbi Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine
    M Strupp
    Department of Neurology, University of Munich, Germany
    Neurology 62:1623-5. 2004
    ..Attacks recurred after treatment was stopped; subsequent treatment alleviated the symptoms (mean follow-up time 6 months). These effects might be due to an improvement of the impaired functioning of Purkinje cells...
  5. ncbi [The most common form of dizziness in middle age: phobic postural vertigo]
    M Strupp
    Neurologische Klinik der Universität München, Klinikum Grosshadern, Munich
    Nervenarzt 74:911-4. 2003
    ..However, when diagnosed correctly, it can be treated successfully in more than 70% of cases. Thus, it takes on considerable medical and socioeconomic significance and should be part of the diagnostic repertoire of every doctor...
  6. ncbi Anterior canal failure: ocular torsion without perceptual tilt due to preserved otolith function
    M Strupp
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    J Neurol Neurosurg Psychiatry 74:1336-8. 2003
    ..A combined ocular torsion and subjective visual vertical tilt, which is usually seen with vestibular lesions, requires an associated otolith dysfunction...
  7. ncbi "Atraumatic" Sprotte needle reduces the incidence of post-lumbar puncture headaches
    M Strupp
    Department of Neurology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Neurology 57:2310-2. 2001
    ..2% of patients in the "atraumatic" group did (p < 0.05). Therefore, use of the "atraumatic" Sprotte needle for lumbar puncture is recommended...
  8. ncbi ["Inner perilymph fistula" of the anterior semicircular canal. A new disease picture with recurrent attacks of vertigo]
    M Strupp
    Neurologische Klinik, Universitätsklinikum Grosshadern, Ludwig Maximilians Universitat Munchen
    Nervenarzt 71:138-42. 2000
    ..Such patients are thus spared unnecessary surgery of the middle ear...
  9. ncbi Acute vestibulopathy
    M Strupp
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Curr Opin Neurol 14:11-20. 2001
    ..Finally, the clinical relevance of recent diagnostic tools (three-dimensional analysis of eye movement, imaging techniques) is discussed...
  10. ncbi Exercise and drug therapy alter recovery from labyrinth lesion in humans
    M Strupp
    Department of Neurology, University of Munich, Klinikum Grosshadern, Germany
    Ann N Y Acad Sci 942:79-94. 2001
    ..3) Preliminary results of an interim analysis from an ongoing randomized, prospective study showed that methylprednisolone (plus an antiviral agent?) may be useful for improving peripheral vestibular function in vestibular neuritis...
  11. ncbi Treatment of downbeat nystagmus with 3,4-diaminopyridine: a placebo-controlled study
    M Strupp
    Department of Neurology, University of Munich, Germany
    Neurology 61:165-70. 2003
    ..These drugs were tested under the assumption that DBN was caused by a disinhibition of a physiologic inhibitory cerebellar input on vestibular nuclei...
  12. ncbi Mind the bend: cerebral activations associated with mental imagery of walking along a curved path
    Judith Wagner
    Department of Neurology, Ludwig Maximilians University, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
    Exp Brain Res 191:247-55. 2008
    ..These data complement earlier findings on the role of anticipatory eye movements during initiation of turns and suggest that there is a very close neurophysiologic relation between locomotion and its mental imagery...
  13. ncbi Saccular function less affected than canal function in bilateral vestibulopathy
    Vera C Zingler
    Dept of Neurology, Ludwig Maximilians University, Klinikum Grosshadern, Marchioninistrasse 15, 81377, Munich, Germany
    J Neurol 255:1332-6. 2008
    ..The latencies P1 and N1 were not significantly different between patients and controls. Thus, in our study population saccular function appeared to be less affected than horizontal semicircular canal function...
  14. ncbi Imaging human supraspinal locomotor centers in brainstem and cerebellum
    Klaus Jahn
    Department of Neurology, University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
    Neuroimage 39:786-92. 2008
    ..This association suggests that deep brain stimulation of locomotion centers may provide new therapeutic approaches for common gait disorders...
  15. ncbi Structural and functional plasticity of the hippocampal formation in professional dancers and slackliners
    Katharina Hüfner
    Department of Neurology, Ludwig Maximilians University, Munich, Germany
    Hippocampus 21:855-65. 2011
    ..This is supported by the concomitant larger volumes in visual areas like the lingual and fusiform gyri. Our findings indicate that there is a spatial separation of vestibular and visual processes in the human hippocampus...
  16. ncbi Unilateral vestibular failure suppresses cortical visual motion processing
    Angela Deutschlander
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Brain 131:1025-34. 2008
    ..This study provides for the first time neuroimaging evidence of suppressed cortical visual motion processing in patients with vestibulopathy...
  17. ncbi Aminopyridines for the treatment of cerebellar and ocular motor disorders
    Michael Strupp
    Department of Neurology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Prog Brain Res 171:535-41. 2008
    ..In conclusion, the use of aminopyridines in DBN, UBN, and EA2 is a new treatment principle for vestibular, cerebellar, and ocular motor disorders...
  18. ncbi Spatial memory and hippocampal volume in humans with unilateral vestibular deafferentation
    Katharina Hüfner
    Department of Neurology, Ludwig Maximilians University, Munich, Germany
    Hippocampus 17:471-85. 2007
    ..Volumetry did not reveal any atrophy of the hippocampus in either patient group...
  19. ncbi The presence of lytic HSV-1 transcripts and clonally expanded T cells with a memory effector phenotype in human sensory ganglia
    Tobias Derfuss
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Ann N Y Acad Sci 1164:300-4. 2009
    ..Thus, HSV-1 IE genes are expressed in human TG, and the infiltrating T cells bear several characteristics that suggest viral antigenic stimulation...
  20. ncbi 4-aminopyridine restores vertical and horizontal neural integrator function in downbeat nystagmus
    Roger Kalla
    Department of Neurology, Ludwig Maximilian University, Munich, Germany
    Brain 130:2441-51. 2007
    ..It may work best when DBN is associated with cerebellar atrophy. Furthermore, 4-AP may be a promising treatment option for patients with a dominant gaze-evoked component of nystagmus, regardless of its etiology...
  21. ncbi Long-term course and relapses of vestibular and balance disorders
    Thomas Brandt
    Institute of Clinical Neurosciences, Germany Integrated Center for Research and Treatment of Vertigo, Balance and Ocular Motor Disorders, Ludwig Maximilian University, Klinikum Grosshadern, Marchioninistr 15, D 81377 Munich, Germany
    Restor Neurol Neurosci 28:69-82. 2010
    ....
  22. ncbi Motivating motorists to voluntarily slow down
    Rainer Spiegel
    Department of Neurology, Ludwig Maximilians University, Munich, Germany
    J Prev Interv Community 38:332-40. 2010
    ..The intervention is a speed-displaying device mounted next to the road (visible to both motorists and the public). Our findings indicate that the device is associated with a significant speed reduction relative to the control condition...
  23. ncbi Torsional eye movement responses to monaural and binaural galvanic vestibular stimulation: side-to-side asymmetries
    Klaus Jahn
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Ann N Y Acad Sci 1004:485-9. 2003
    ..It is necessary to know the normal range of asymmetry between left- and right-sided stimulation to interpret GVS responses in patients with vestibular diseases...
  24. ncbi Supraspinal locomotor control in quadrupeds and humans
    Klaus Jahn
    Department of Neurology, University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
    Prog Brain Res 171:353-62. 2008
    ..It is conceivable that electrical stimulation of locomotor brain stem centres may initiate and improve gait in selected patients suffering from Parkinson's disease or progressive supranuclear palsy...
  25. ncbi Causative factors and epidemiology of bilateral vestibulopathy in 255 patients
    Vera C Zingler
    Department of Neurology, Ludwig Maximilians University, Klinikum Grosshadern, Munich, Germany
    Ann Neurol 61:524-32. 2007
    ..To determine the causative factors and epidemiology of bilateral vestibulopathy (BV)...
  26. ncbi Immunosuppressive treatment in bilateral vestibulopathy with inner ear antibodies
    Angela Deutschlander
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Acta Otolaryngol 125:848-51. 2005
    ..These data do not allow us to generally recommend corticosteroid treatment in patients with BVF and inner ear antibodies...
  27. ncbi Presence of HSV-1 immediate early genes and clonally expanded T-cells with a memory effector phenotype in human trigeminal ganglia
    Tobias Derfuss
    Institute of Clinical Neuroimmunology, University Clinic, Munich, Germany
    Brain Pathol 17:389-98. 2007
    ..Thus, HSV-1 IE genes are expressed in human TG and the infiltrating T-cells bear several characteristics that suggest viral antigenic stimulation...
  28. ncbi The prevalence of human herpesvirus 6 in human sensory ganglia and its co-occurrence with alpha-herpesviruses
    Katharina Hüfner
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistrasse 23, Munich, Germany
    J Neurovirol 13:462-7. 2007
    ..As HHV-6 positivity did not depend on the presence of inflammatory cells, known to harbor the virus, HHV-6 probably resides in the ganglia themselves...
  29. ncbi Bedside differentiation of vestibular neuritis from central "vestibular pseudoneuritis"
    C D Cnyrim
    Department of Neurology, University of Munich, Marchioninistr 15, D 81377 Munich, Germany
    J Neurol Neurosurg Psychiatry 79:458-60. 2008
    ..None of the other isolated signs (head thrust test, saccadic pursuit, gaze evoked nystagmus, subjective visual vertical) were reliable; however, multivariate logistic regression increased their sensitivity and specificity to 92%...
  30. ncbi Human hippocampal activation during stance and locomotion: fMRI study on healthy, blind, and vestibular-loss subjects
    Klaus Jahn
    Ludwig Maximilians University, Klinikum Grosshadern, Department of Neurology, Marchioninistrasse, Munich, Germany
    Ann N Y Acad Sci 1164:229-35. 2009
    ..The right-sided dominance reflects the importance of the right hemisphere for spatial orientation...
  31. ncbi An ipsilateral vestibulothalamic tract adjacent to the medial lemniscus in humans
    Andreas Zwergal
    Department of Neurology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Brain 131:2928-35. 2008
    ....
  32. ncbi Imagined locomotion in the blind: an fMRI study
    Angela Deutschlander
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Neuroimage 45:122-8. 2009
    ..This is accompanied by enhanced voluntary motor control and enhanced motor-kinesthetic processing. Thus, we provide neuroimaging evidence of distinct sensorimotor strategies in the blind for locomotor control...
  33. ncbi Fewer latent herpes simplex virus type 1 and cytotoxic T cells occur in the ophthalmic division than in the maxillary and mandibular divisions of the human trigeminal ganglion and nerve
    Katharina Hüfner
    Department of Neurology, Klinikum Grosshadern, Marchioninistr 23, 81377 Munich, Germany
    J Virol 83:3696-703. 2009
    ..In conclusion, the large accumulation of LAT and cytotoxic T cells in the V2 and V3 but not in the V1 division of the TG reflects the sites supplied by the sensory fibers and the clinical reactivation patterns...
  34. ncbi Vestibular cortex activation during locomotor imagery in the blind
    Angela Deutschlander
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Ann N Y Acad Sci 1164:350-2. 2009
    ..Thus, this fMRI study provides neuroimaging evidence for distinct cortical processing in the multisensory vestibular system in the blind during locomotor control...
  35. ncbi Latency of herpes simplex virus type-1 in human geniculate and vestibular ganglia is associated with infiltration of CD8+ T cells
    Viktor Arbusow
    Clinic of Neurology am Marienplatz, Munich, Germany
    J Med Virol 82:1917-20. 2010
    ..Colocalization of latent HSV-1 and CD8+ T cells in geniculate and vestibular ganglia supports further the hypothesis that HSV-1 reactivation is possible in these ganglia and is the cause of Bell's palsy and vestibular neuritis...
  36. ncbi Real versus imagined locomotion: a [18F]-FDG PET-fMRI comparison
    Christian la Fougere
    Department of Nuclear Medicine, Ludwig Maximilians University of Munich, Germany
    Neuroimage 50:1589-98. 2010
    ..Real steady-state locomotion seems to use a direct pathway via the primary motor cortex, whereas imagined modulatory locomotion an indirect pathway via a supplementary motor cortex and basal ganglia loop...
  37. ncbi Spatial separation of visual and vestibular processing in the human hippocampal formation
    Katharina Hüfner
    Department of Neurology Integrated Center for Research and Treatment of Vertigo IFBLMU, Ludwig Maximilians University, Munich, Germany
    Ann N Y Acad Sci 1233:177-86. 2011
    ....
  38. ncbi Comparison of 10-mg doses of 4-aminopyridine and 3,4-diaminopyridine for the treatment of downbeat nystagmus
    Roger Kalla
    Department of Neurology and IFB, Munich University Hospital, Campus Grosshadern, Munich, Germany
    J Neuroophthalmol 31:320-5. 2011
    ..In this double-blind, prospective, crossover study, the effects of equivalent doses of 4-AP and 3,4-DAP on the slow-phase velocity (SPV) of downbeat nystagmus were compared...
  39. ncbi Cerebellar and visual gray matter brain volume increases in congenital nystagmus
    Katharina Hüfner
    Department of Neurology, Hospital of the University of Munich, Ludwig Maximilians University Munich, Germany
    Front Neurol 2:60. 2011
    ....
  40. ncbi Nicotine-induced nystagmus correlates with midpontine activation
    Angela Deutschlander
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistr 15, 81377 Munich, Germany
    Neuroimage 41:479-82. 2008
    ....
  41. ncbi A clinical test of otolith function: static ocular counterroll with passive head tilt
    Vera C Zingler
    Department of Neurology, Ludwig Maximilians University, Klinikum Grosshadern, Munich, Germany
    Neuroreport 17:611-5. 2006
    ..Utricular function can thus be tested simply by measuring passive head tilt with video-oculography...
  42. ncbi Latent herpesvirus infection in human trigeminal ganglia causes chronic immune response
    Diethilde Theil
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Am J Pathol 163:2179-84. 2003
    ..The chronic immune response seems to maintain viral latency and influence viral reactivation...
  43. ncbi Eccentric eye and head positions in darkness induce deviation from the intended path
    Klaus Jahn
    Klinikum Grosshadern, Department of Neurology, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Exp Brain Res 174:152-7. 2006
    ..The direction of deviation may reflect the compensation of an expected or perceived deviation in the direction of gaze...
  44. ncbi Prevalence and distribution of HSV-1, VZV, and HHV-6 in human cranial nerve nuclei III, IV, VI, VII, and XII
    Diethilde Theil
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    J Med Virol 74:102-6. 2004
    ..The absence of LAT in the samples positive for HSV-1 and the distribution of HSV-1 and HHV-6 do not support the hypothesis that idiopathic cranial nerve palsies result from viral reactivation in the brainstem nuclei...
  45. ncbi Gait deviations induced by visual stimulation in roll
    Erich Schneider
    Department of Neurology, University Hospital of Munich Grosshadern Ludwig Maximilians University, Marchioninistr 23, 81377, Munich, Germany
    Exp Brain Res 185:21-6. 2008
    ..Both kinds of stimulation cause only initial balance responses in the roll plane but do not contribute to the steering of gait in the yaw plane...
  46. ncbi Causative factors, epidemiology, and follow-up of bilateral vestibulopathy
    Vera Carina Zingler
    Department of Neurology, Ludwig Maximilians University, Munich, Germany
    Ann N Y Acad Sci 1164:505-8. 2009
    ..0 +/- 1.4 degrees/s vs. 1.9 +/- 1.6 degrees/s). Forty-three percent of patients subjectively rated the course of their disease as stable, 28% as worsened, and 29% as improved...
  47. ncbi Gray-matter atrophy after chronic complete unilateral vestibular deafferentation
    Katharina Hüfner
    Department of Neurology, Ludwig Maximilians University, Munich, Germany
    Ann N Y Acad Sci 1164:383-5. 2009
    ..In comparison to healthy controls, no regional increases in gray-matter volume were seen. No white-matter changes were detected at the selected threshold...
  48. ncbi Institutional profile: integrated center for research and treatment of vertigo, balance and ocular motor disorders
    Thomas Brandt
    Institute of Clinical Neurosciences, Ludwig Maximilian University, Klinikum Grosshadern, Marchioninistr 15, D 81377 Munich, Germany
    Restor Neurol Neurosci 28:135-43. 2010
    ..This should also be seen as an incentive that will attract the best young scientists; to incorporate (IFB(LMU)) competence into the existing medical and biological graduate schools. The (IFB(LMU)) is a unique center - worldwide...
  49. ncbi The intensity of downbeat nystagmus during daytime
    Rainer Spiegel
    Department of Neurology, University of Munich, Munich, Germany
    Ann N Y Acad Sci 1164:293-9. 2009
    ..This change during daytime did not depend on visual fixation. Another possible mechanism is the modulation of DBN by head position relative to gravity, that is, by otolith input. This should be evaluated in further studies...
  50. ncbi Suppression of eye movements improves balance
    Klaus Jahn
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Brain 125:2005-11. 2002
    ..Thus, ocular motor signals rather than afferent visual cues about retinal slip are used for visual control of postural sway, at least in this experimental paradigm...
  51. ncbi Inverse U-shaped curve for age dependency of torsional eye movement responses to galvanic vestibular stimulation
    Klaus Jahn
    MD Department of Neurology, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
    Brain 126:1579-89. 2003
    ..Thus, the compensatory increase in sensitivity breaks down and GVS-induced eye movements decline-a finding that is reflected by the inverse U-shaped curve for age dependency presented in this study...
  52. ncbi Clinical, electrophysiological, and MRI findings in patients with cerebellar ataxia and a bilaterally pathological head-impulse test
    Hanni Kirchner
    Department of Neurology and IFB LMU Institute for Clinical Neurosciences, University Hospital Munich, Munich, Germany
    Ann N Y Acad Sci 1233:127-38. 2011
    ..This multisensory syndrome is most likely caused by a neurodegenerative disorder affecting different systems, leading to severe impairment of affected patients...
  53. ncbi Effect of 4-aminopyridine on upbeat and downbeat nystagmus elucidates the mechanism of downbeat nystagmus
    Stefan Glasauer
    Center for Sensorimotor Research, Department of Neurology, Ludwig Maximilian University, Munich, Germany
    Ann N Y Acad Sci 1039:528-31. 2005
    ..We hypothesize that this difference in the effects of 4-AP, which is known to increase the excitability of cerebellar Purkinje cells, can be attributed to the different lesion sites involved in UBN and DBN...
  54. ncbi Long-term prophylactic treatment of attacks of vertigo in Menière's disease--comparison of a high with a low dosage of betahistine in an open trial
    Michael Strupp
    Department of Neurology, University of Munich, Munich, Germany
    Acta Otolaryngol 128:520-4. 2008
    ....
  55. ncbi Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans
    Thomas Brandt
    Department of Neurology, Ludwig Maximilians University, Munich, Germany
    Brain 128:2732-41. 2005
    ..g. without any actual vestibular or somatosensory stimulation...
  56. ncbi High-dosage betahistine dihydrochloride between 288 and 480 mg/day in patients with severe Menière's disease: a case series
    Franziska Lezius
    Department of Neurology, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
    Eur Arch Otorhinolaryngol 268:1237-40. 2011
    ..Moreover, such dosages are well tolerated...
  57. ncbi Prognosis of idiopathic downbeat nystagmus
    Judith Wagner
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Ann N Y Acad Sci 1164:479-81. 2009
    ..Neither the slow-phase velocity (SPV) nor the dependency of the SPV on gaze position as an indicator of dysfunction of the oculomotor velocity-to-position integrator changed significantly over the time course investigated in this study...
  58. ncbi Vestibular neuritis
    Michael Strupp
    Department of Neurology, University of Munich, Munich, Germany
    Semin Neurol 29:509-19. 2009
    ....
  59. ncbi Episodic ataxia type 2
    Michael Strupp
    Department of Neurology, University of Munich, Munich, Germany
    Neurotherapeutics 4:267-73. 2007
    ..Many aspects of the pathophysiology (e.g., induction of the attacks) and treatment of EA 2 (e.g., mode of action of ACTZ and 4-AP) still remain unclear and need to be addressed in further animal and clinical studies...
  60. ncbi Medical treatment of vestibular disorders
    Thomas Brandt
    Ludwig Maximilians University, Institute of Clinical Neuroscience, Marchioninistr 15, 81377 Munich, Germany
    Expert Opin Pharmacother 10:1537-48. 2009
    ..However, the majority of vestibular disorders have a benign cause, take a favorable natural course, and respond positively to therapy...
  61. ncbi Long-term course of Menière's disease revisited
    Doreen Huppert
    Institute of Clinical Neurosciences, University of Munich, Munich, Germany
    Acta Otolaryngol 130:644-51. 2010
    ..The investigated studies disclose a large variability of the many symptoms appearing in the course of Menière's disease...
  62. ncbi Spatial memory deficits in patients with chronic bilateral vestibular failure
    Franz Schautzer
    Ludwig Maximilians University, 81377 Munich, Germany
    Ann N Y Acad Sci 1004:316-24. 2003
    ..These deficits can even be demonstrated with the subjects stationary, i.e., without any actual vestibular or somatosensory stimulation...
  63. ncbi Central compensation of deviated subjective visual vertical in Wallenberg's syndrome
    Christian Daniel Cnyrim
    Department of Neurology, University of Munich, Marchioninistr 15, D 81377 Munich, Germany
    J Neurol Neurosurg Psychiatry 78:527-8. 2007
    ..This finding shows that the time courses of the central compensation for dorsolateral medullary infarctions and peripheral vestibular lesions are similar...
  64. ncbi Dually infected (HSV-1/VZV) single neurons in human trigeminal ganglia
    Diethilde Theil
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistrasse 23, 81377 Munich, Germany
    Ann Neurol 54:678-82. 2003
    ..Latency transcripts of both viruses were detected in common areas within the ganglia. Also, a few single neurons were shown to harbor HSV-1 and VZV together...
  65. ncbi Pharmacological advances in the treatment of neuro-otological and eye movement disorders
    Michael Strupp
    Department of Neurology, University of Munich, Germany
    Curr Opin Neurol 19:33-40. 2006
    ..Second, to identify vestibular and ocular motor disorders in which treatment trials are warranted...
  66. ncbi Both actual and imagined locomotion suppress spontaneous vestibular nystagmus
    Klaus Jahn
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
    Neuroreport 13:2125-8. 2002
    ..003, = 10). The suppression of vestibular nystagmus might be beneficial for patients, for it alleviates the disturbing impression of movement of the visual scene (oscillopsia) caused by involuntary eye movements...
  67. ncbi Parallel ascending vestibular pathways: anatomical localization and functional specialization
    Andreas Zwergal
    Department of Neurology, Ludwig Maximilians University of Munich, Munich, Germany
    Ann N Y Acad Sci 1164:51-9. 2009
    ....
  68. ncbi Current treatment of vestibular, ocular motor disorders and nystagmus
    Michael Strupp
    Professor of Neurology and Clinical Neurophysiology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Ther Adv Neurol Disord 2:223-39. 2009
    ....
  69. ncbi Benign paroxysmal positioning vertigo: a long-term follow-up (6-17 years) of 125 patients
    Thomas Brandt
    Department of Neurology, Ludwig Maximilians University, Munich, Germany
    Acta Otolaryngol 126:160-3. 2006
    ..The study disclosed a few predictive factors for benign paroxysmal positioning vertigo (BPPV) recurrences, which are clinically relevant and essential for patient awareness of the often long-term course of the condition...
  70. ncbi Bilateral vestibular failure as an early sign in Creutzfeldt-Jakob disease
    Klaus Jahn
    Departments of Neurology, of Neurology, Klinikum Grosshadern Marchioninistrasse 15, 81377 Munich, Germany
    Ann N Y Acad Sci 1164:390-3. 2009
    ..The vestibular nuclei are known to be severely affected in animal spongiform encephalopathies. They might also be a vulnerable target in human prion diseases...
  71. ncbi Superficial cerebral and spinal haemosiderosis caused by secondary tethered cord syndrome after resection of a spinal lymphoma
    Vera C Zingler
    Department of Neurology, Ludwig Maximilians University, Klinikum Grosshadern, D 81377 Munich, Germany
    J Neurol Neurosurg Psychiatry 78:767-8. 2007
    ....
  72. ncbi Integrated center for research and treatment of vertigo, balance and ocular motor disorders
    Thomas Brandt
    Institute of Clinical Neurosciences, Ludwig Maximilian University, D 81377 Munich, Germany
    Restor Neurol Neurosci 28:1-8. 2010
    ..With funding of 50 euros million over a ten-year period, the long-term continuation of the IFB(LMU) is envisioned...
  73. ncbi Vaccination against herpes zoster, small RNA against ALS and IgG antibodies in stiff-person syndrome
    Michael Strupp
    Dept. of Neurology, Ludwig-Maximilians University, Klinikum Grosshadern, Marchioninistr. 15, 81366 Munich, Germany
    J Neurol 252:869-71. 2005
  74. ncbi General vestibular testing
    Thomas Brandt
    Department of Neurology, Ludwig Maximilians University, Marchioninistr 15, 81377 Munich, Germany
    Clin Neurophysiol 116:406-26. 2005
    ..It must, however, be kept in mind that all signs and ocular motor and vestibular findings have to be interpreted within the context of the patient's history and a complete neurological examination...
  75. ncbi Stent grafting resolved brachial plexus neuropathy due to cervical arteriovenous fistula
    Vera Carina Zingler
    Department of Neurology, University of Munich, Munich, Germany
    Eur Neurol 52:250-1. 2004
  76. ncbi Hemihypomimia in Parkinson's disease
    Vera C Zingler
    Department of Neurology, Ludwig Maximilians University, Klinikum Grosshadern, Munich, Germany
    Eur Neurol 53:92-3. 2005
  77. ncbi Mitoxantrone therapy in multiple sclerosis and acute leukaemia: a case report out of 644 treated patients
    Raymond Voltz
    Institute of Clinical Neuroimmunology, Klinikum Grosshadern, Munchen, Germany
    Mult Scler 10:472-4. 2004
    ..This report brings the currently published frequency of MITOX-associated TRAL in MS therapy to five in a total of 2336 treated MS patients, representing an incidence of 0.21%...
  78. ncbi Brain activation patterns during imagined stance and locomotion in functional magnetic resonance imaging
    Klaus Jahn
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich 81377, Germany
    Neuroimage 22:1722-31. 2004
    ..Postural control during standing involves a low intensity cerebellar activity and sensorimotor control via the thalamus and basal ganglia...
  79. ncbi Assessment of potential cardiotoxic side effects of mitoxantrone in patients with multiple sclerosis
    Vera Carina Zingler
    Department of Neurology, University of Munich, Munich, Germany
    Eur Neurol 54:28-33. 2005
    ..Mitoxantrone did not cause signs of congestive heart failure in any of the patients. Further cardiac monitoring is, however, needed to determine the safety of mitoxantrone after longer follow-up times and at higher cumulative doses...
  80. ncbi Spatial neglect: hypothetical mechanisms of disturbed interhemispheric crosstalk for orientation
    Thomas Brandt
    Institute of Clinical Neurosciences, Ludwig Maximilians University, Munich, Germany
    Ann N Y Acad Sci 1164:216-21. 2009
    ..The nondominant MSO in the left hemisphere might be involved in the manifestation of the less frequent and more transient right-sided neglect and in the plastic mechanisms of gradual recovery from a left-sided neglect or extinction...
  81. ncbi Expression of neuronal markers in differentiated marrow stromal cells and CD133+ stem-like cells
    Claudio S Padovan
    Department of Neurology, Ludwig Maximilian University, Munich, Germany
    Cell Transplant 12:839-48. 2003
    ..CD133+ mesenchymal stem-like cells, but not CD34+/CD133- cells, generally showed a higher expression of neuronal markers than did unsorted marrow stromal cells, and differentiated CD133+ cells more resembled neuron-like cells...
  82. ncbi Cranial nerve palsies: herpes simplex virus type 1 and varizella-zoster virus latency
    Diethilde Theil
    Ann Neurol 51:273-4. 2002
  83. ncbi Perverted head-shaking nystagmus: two possible mechanisms
    Michael Strupp
    Dept. of Neurology, , Munich, Germany. mstrupp.nefo.med.uni-muenchen.de
    J Neurol 249:118-9. 2002
  84. ncbi Does alcohol cancel static vestibular compensation?
    Vera C Zingler
    Ann Neurol 55:144-5. 2004
  85. ncbi The bioavailability of IV methylprednisolone and oral prednisone in multiple sclerosis
    Michael Strupp
    Neurology 64:1100; author reply 1100. 2005
  86. ncbi [Calming most patients with vertigo. The course is usually benign--therapy successful (interview by Dr. Judith Neumaier)]
    Michael Strupp
    MMW Fortschr Med 146:10. 2004
  87. ncbi Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia--a comment
    Michael Strupp
    Brain 128:E32; author reply E33. 2005
  88. ncbi Upbeat nystagmus as the initial clinical sign of Creutzfeldt-Jakob disease
    Vera Carina Zingler
    Ann Neurol 57:607-8. 2005
  89. ncbi What to do for the neurologist who has a screw loose: glue and the art of tuning fork maintenance
    Stefan Kastenbauer
    Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany
    Neurology 63:1328. 2004