Jurgen Steinmeyer

Summary

Affiliation: University of Giessen
Country: Germany

Publications

  1. ncbi Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts
    Elena Neumann
    Department of Internal Medicine and Rheumatology, University of Giessben, Kerckhoff Klinik, D 61231 Bad Nauheim, Benekestr, 2 8, Germany
    Arthritis Res Ther 12:R83. 2010
  2. ncbi In vitro inhibition of aggrecanase activity by tetracyclines and proteoglycan loss from osteoarthritic human articular cartilage
    Jurgen Steinmeyer
    Department of Orthopaedic Surgery, University Hospital Giessen and Marburg GmbH, Giessen, Germany
    J Orthop Res 28:828-33. 2010
  3. ncbi Pharmacological basis for the therapy of pain and inflammation with nonsteroidal anti-inflammatory drugs
    J Steinmeyer
    Department of Orthopaedic Surgery, Justus Liebig University of Giessen, Germany
    Arthritis Res 2:379-85. 2000
  4. ncbi Oral treatment options for degenerative joint disease--presence and future
    Jurgen Steinmeyer
    Clinic and Policlinic of Orthopaedics and Orthopaedic Surgery, University Hospital Giessen and Marburg GmbH, Paul Meimberg Strasse 3, D 35385 Giessen, Germany
    Adv Drug Deliv Rev 58:168-211. 2006
  5. ncbi Cytokines in osteoarthritis-current status on the pharmacological intervention
    Juergen Steinmeyer
    Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, Justus Liebig University of Giessen, Paul Meimberg Str 3, D 35385 Giessen, Germany
    Front Biosci 9:575-80. 2004
  6. ncbi [Drug therapy of arthrosis]
    J Steinmeyer
    Orthopadische Klinik, Universitätsklinikum Giessen
    Orthopade 30:856-65. 2001
  7. ncbi Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: a 2-year randomised study
    Erhan Basad
    Clinic and Polyclinic for Orthopaedic Surgery, University Hospital Giessen Marburg GmbH, Giessen
    Knee Surg Sports Traumatol Arthrosc 18:519-27. 2010
  8. ncbi Catabolic properties of microdissected human endosteal bone lining cells
    C Dierkes
    Department of Pathology, Justus Liebig University, Langhansstr 10, Giessen 35385, Germany
    Calcif Tissue Int 84:146-55. 2009
  9. ncbi [Treatment of osteochondral defects of the knee with autologous bone graft and chondrocyte transplantation: an overview together with our results]
    Erhan Basad
    Clinic and Polyclinic for Orthopedics and Orthopedic Surgery, University of Giessen Marburg Hospital, Giessen, Germany
    Acta Orthop Traumatol Turc 41:79-86. 2007
  10. ncbi Collagen synthesis of articular cartilage explants in response to frequency of cyclic mechanical loading
    Amela Wolf
    Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University Clinics Giessen and Marburg, Paul Meimberg Strasse 3, 35385 Giessen, Germany
    Cell Tissue Res 327:155-66. 2007

Collaborators

Detail Information

Publications11

  1. ncbi Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts
    Elena Neumann
    Department of Internal Medicine and Rheumatology, University of Giessben, Kerckhoff Klinik, D 61231 Bad Nauheim, Benekestr, 2 8, Germany
    Arthritis Res Ther 12:R83. 2010
    ..We evaluated, whether passaging during culture and freezing has effects on gene expression and cell proliferation...
  2. ncbi In vitro inhibition of aggrecanase activity by tetracyclines and proteoglycan loss from osteoarthritic human articular cartilage
    Jurgen Steinmeyer
    Department of Orthopaedic Surgery, University Hospital Giessen and Marburg GmbH, Giessen, Germany
    J Orthop Res 28:828-33. 2010
    ..Altogether, our data show that tetracyclines have no inhibitory potential on any proteoglycanolytic activities within mild or moderately affected human OA cartilage at therapeutic achievable plasma levels...
  3. ncbi Pharmacological basis for the therapy of pain and inflammation with nonsteroidal anti-inflammatory drugs
    J Steinmeyer
    Department of Orthopaedic Surgery, Justus Liebig University of Giessen, Germany
    Arthritis Res 2:379-85. 2000
    ..This knowledge is important for the effective treatment of pain and inflammation, as well as for preventing serious and sometimes lethal gastrointestinal side effects...
  4. ncbi Oral treatment options for degenerative joint disease--presence and future
    Jurgen Steinmeyer
    Clinic and Policlinic of Orthopaedics and Orthopaedic Surgery, University Hospital Giessen and Marburg GmbH, Paul Meimberg Strasse 3, D 35385 Giessen, Germany
    Adv Drug Deliv Rev 58:168-211. 2006
    ..Disease modifying therapy is still in its infancy; discovery and development of novel therapeutic targets and agents are an extremely difficult task, currently challenging many pharmaceutical companies and academic institutions...
  5. ncbi Cytokines in osteoarthritis-current status on the pharmacological intervention
    Juergen Steinmeyer
    Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, Justus Liebig University of Giessen, Paul Meimberg Str 3, D 35385 Giessen, Germany
    Front Biosci 9:575-80. 2004
    ....
  6. ncbi [Drug therapy of arthrosis]
    J Steinmeyer
    Orthopadische Klinik, Universitätsklinikum Giessen
    Orthopade 30:856-65. 2001
    ..Pharmacotherapy should only be considered as one of the three pillars of a long-term,stage-adjusted, and individually customized therapy, the other two of which are represented by nonpharmacological measures and surgical treatment...
  7. ncbi Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: a 2-year randomised study
    Erhan Basad
    Clinic and Polyclinic for Orthopaedic Surgery, University Hospital Giessen Marburg GmbH, Giessen
    Knee Surg Sports Traumatol Arthrosc 18:519-27. 2010
    ....
  8. ncbi Catabolic properties of microdissected human endosteal bone lining cells
    C Dierkes
    Department of Pathology, Justus Liebig University, Langhansstr 10, Giessen 35385, Germany
    Calcif Tissue Int 84:146-55. 2009
    ..The new diode-laser microdissection with LMD and LPC proved to be especially suitable to gain new insights into the properties of bone lining cells...
  9. ncbi [Treatment of osteochondral defects of the knee with autologous bone graft and chondrocyte transplantation: an overview together with our results]
    Erhan Basad
    Clinic and Polyclinic for Orthopedics and Orthopedic Surgery, University of Giessen Marburg Hospital, Giessen, Germany
    Acta Orthop Traumatol Turc 41:79-86. 2007
    ..In this prospective study, we evaluated clinical and magnetic resonance imaging (MRI) findings after one and two years of this treatment method...
  10. ncbi Collagen synthesis of articular cartilage explants in response to frequency of cyclic mechanical loading
    Amela Wolf
    Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University Clinics Giessen and Marburg, Paul Meimberg Strasse 3, 35385 Giessen, Germany
    Cell Tissue Res 327:155-66. 2007
    ..Moreover, the unaltered or reduced collagen synthesis of cartilage explants might reflect more closely the metabolism of normal or early human osteoarthritic cartilage...
  11. ncbi Analysis of vascular gene expression in arthritic synovium by laser-mediated microdissection
    Atsushi Hashimoto
    Department of Medicine and Rheumatology, Justus Liebig University of Giessen, Giessen, and University Hospital Regensburg, Germany
    Arthritis Rheum 56:1094-105. 2007
    ..The aim of this study was to analyze the specific synovial vascular expression profiles of several angiogenesis-related genes as well as CD82 in RA compared with osteoarthritis (OA), using laser-mediated microdissection (LMM)...