Research Topics
| Frank SommerSummaryAffiliation: University of Cologne Country: Germany Publications
| Collaborators
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Detail Information
Publications
Comparison of individual urologists' performanceF Sommer
Department of Urology, University Medical Centre of Cologne, and Paracelsus Klinik Golzheim, Dusseldorf, Germany
Eur Urol 39:369-74. 2001..The purpose of our study was to compare the crude operative morbidity and mortality rates with the predicted rates using an established scoring system (POSSUM)...- [Levitra in a hardness test]Frank Sommer
, Postfach 41 1043,
Krankenpfl J 42:120. 2004 - Future options for combination therapy in the management of erectile dysfunction in older menFrank Sommer
Department of Urology, University Medical Centre Cologne, Cologne, Germany
Drugs Aging 21:555-64. 2004..Preliminary observations of combination therapy have been encouraging and provide a scientific rationale for prospective, randomised clinical trials with adequate numbers of patients... - Lifestyle issues and genitourinary tumoursFrank Sommer
Klinik und Poliklinik fur Urologie der Universitat zu Koln, Joseph Stelzmann Str 9, 50931 Koln, Germany
World J Urol 21:402-13. 2004..This survey demonstrates that the individual assessment of lifestyle factors not only may identify groups with an increased risk for urological malignancies but also clearly displays a potential for tumour prevention... - Epidemiology of Peyronie's diseaseF Sommer
Department of Urology, University Medical Center of Cologne, Cologne, Germany
Int J Impot Res 14:379-83. 2002..Comparably high prevalences are known for diabetes and urolithiasis, suggesting a greater frequency of this rare disease than formerly believed... - MAP kinase 1/2 (Erk 1/2) and serine/threonine specific protein kinase Akt/PKB expression and activity in the human corpus cavernosumF Sommer
Department of Urology, University Medical Centre of Cologne, Cologne, Germany
Int J Impot Res 14:217-25. 2002..Furthermore, we found a higher basal level of active MAP Kinase 1/2 (Erk 1/2) in impotent patients. This finding gives the first evidence for an inhibitory influence of MAP Kinase 1/2 (Erk 1/2) on cavernosal eNOS activity... - Creative-dynamic image synthesis: a useful addition to the treatment options for impotenceF Sommer
Department of Urology, University Medical Center of Cologne, Germany
Int J Impot Res 13:268-74; discussion 275. 2001..Creative-dynamic image synthesis is a potent initiator of erections in men with psychogenic erectile dysfunction, has no known side effects and is very cost-effective... - Impotence and genital numbness in cyclistsF Sommer
Department of Urology, University Medical Center of Cologne, Germany
Int J Sports Med 22:410-3. 2001..Therefore, we suggest restricting the training distance, and taking sufficient pauses during the course of prolonged and vigorous bicycle riding, in order to avoid penile numbness and impotence... - [Changes in penile blood flow during cycling--how does one prevent a decreased perfusion?]F Sommer
Klinik und Poliklinik für Urologie der Universität Köln, Germany
Dtsch Med Wochenschr 126:939-43. 2001..2 years) transcutaneous penile oxygen pressure (tpO (2)) at the glans penis was measured during cycling in different positions and with different types of saddle, using a modified Clark oxygen electrode... - Erectile dysfunction in cyclists. Is there any difference in penile blood flow during cycling in an upright versus a reclining position?F Sommer
Department of Urology, University Medical Centre of Cologne, Germany
Eur Urol 39:720-3. 2001..Perineal compression during bicycling appears to be responsible for some cases of erectile dysfunction... - [Value of cryotherapy in localized prostatic carcinoma]F Sommer
Klinik und Poliklinik fur Urologie, Universitat zu Koln, Joseph Stelzmann Strasse 9, 50924 Köln
Urologe A 40:185-90. 2001..Control with thermocouples, ultrasound, and double-freeze techniques makes it possible to destroy the whole organ or the region of interest in high-risk patients or in patients who refuse to undergo open surgical procedures... - Vardenafil Bayer YakuhinFrank Sommer
Department of Urology, University Medical Center of Cologne, Germany
Curr Opin Investig Drugs 3:607-13. 2002..In July 2001, Lehman Brothers predicted a 75% chance that vardenafil would reach the market, and forecast peak sales of US $0.85 billion worldwide; the analyst also speculated that Bayer would seek a comarketing partner [414766]... - Cycling and penile oxygen pressure: the type of saddle mattersUlrich Schwarzer
Department of Urology, University Medical Center of Cologne, Germany
Eur Urol 41:139-43. 2002..It was possible to demonstrate that the most important factor in safeguarding penile perfusion is not the amount of padding, but rather a saddle width which prevents sufficiently the compression of the perineal arteries... - Nitric oxide pathways in human bladder carcinoma. The distribution of nitric oxide synthases, soluble guanylyl cyclase, cyclic guanosine monophosphate, and nitrotyrosineAmgad Ehsan
Department of Urology, University of Wuerzburg, Wuerzburg, Germany
Cancer 95:2293-301. 2002..Increased angiogenesis is a cGMP-mediated effect, while nitrotyrosine production is a non cGMP-mediated oxidative effect. Such an NO/oxidative pathway is observed more often in bladder carcinoma... - Patients responding to phosphodiesterase type 5 inhibitor therapy: what do their sexual partners know?Theodor Klotz
Department of Urology, Klinikum Weiden, Weiden, Germany
J Sex Med 4:162-5. 2007..Phosphodiesterase type 5 (PDE5) inhibitors are an efficacious therapy in men with erectile dysfunction (ED). There are only a few studies that also focus on the participating couples during PDE5 inhibitor therapy... - Bicycle riding and erectile dysfunction: a reviewFrank Sommer
Department of Urology, Institute of Men s Health, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
J Sex Med 7:2346-58. 2010..For many years, reports in the literature have implicated bicycle riding as causing increased risk of erectile dysfunction (ED). Perineal compression during cycling has been associated with the development of sexual complications... - Prospective randomized Phase II trial of pegylated doxorubicin in the management of symptomatic hormone-refractory prostate carcinomaAxel Heidenreich
Department of Urology, University of Cologne, Germany
Cancer 101:948-56. 2004.... - Treating erectile dysfunction by endothelial rehabilitation with phosphodiesterase 5 inhibitorsFrank Sommer
Department of Men's Health and Clinic of Urology, University Hospital Hamburg-Eppendorf, P.O. Box 202101, 20214, Hamburg, Germany
World J Urol 23:385-92. 2005..The present review focuses on several recent studies which provide evidence for the beneficial effect of regular PDE5 inhibitor administration on the improvement of EF by rehabilitation of vascular endothelium... - Evaluation of tetrahydrobiopterin (BH4) as a potential therapeutic agent to treat erectile dysfunctionFrank Sommer
Department of Men's Health, University Medical Center Hamburg-Eppendorf, Postfach 202101, Hamburg, DE-20264, Germany
Asian J Androl 8:159-67. 2006..The observed results make BH4 a suitable candidate as an ED treatment through reconstitution of altered catalytic activity of the eNOS... - Potency and selectivity of vardenafil: a phosphodiesterase Type 5 inhibitorFrank Sommer
Department of Men's Health and Department of Urology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, DE-20246 Hamburg, Germany
Expert Opin Drug Metab Toxicol 1:295-301. 2005..This review will discuss the findings of biochemical, in vitro and in vivo experiments that indicate the superior potency and high selectivity of vardenafil... - [Continuous once a day treatment with sildenafil: daily sex prevents the "aging penis"]Frank Sommer
MMW Fortschr Med 145:59. 2003 - Improved spontaneous erectile function in men with mild-to-moderate arteriogenic erectile dysfunction treated with a nightly dose of sildenafil for one year: a randomized trialFrank Sommer
Department of Men s Health, University Medical Center Hamburg Eppendorf, Hamburg 20214, Germany
Asian J Androl 9:134-41. 2007..To test the hypothesis that sildenafil (50 mg nightly for one year) can improve spontaneous erectile function (EF) in men with mild-to-moderate arteriogenic erectile dysfunction (ED) responsive to erectogenic treatment... - Long-term treatment of erectile dysfunction with a phosphodiesterase-5 inhibitor and dose optimization based on nocturnal penile tumescenceMichael J Mathers
Urological Ambulatory Remscheid, Remscheid, Germany
BJU Int 101:1129-34. 2008.... - Comparable efficacy of once-daily versus on-demand vardenafil in men with mild-to-moderate erectile dysfunction: findings of the RESTORE studyJurgen Zumbe
Klinikum Leverkusen, Leverkusen, Germany
Eur Urol 54:204-10. 2008..Phosphodiesterase (type) 5 (PDE5) inhibitors are currently administered on demand for treatment of erectile dysfunction (ED). Once-daily dosing has been suggested to benefit patients... - Daphnia versus copepod impact on summer phytoplankton: functional compensation at both trophic levelsUlrich Sommer
Institut für Meereskunde, Düsternbrooker Weg 20, 24105, Kiel, Germany
Oecologia 135:639-47. 2003..10 days. Contrary to the impact of a single functional group, the combined impact of both zooplankton groups led to a substantial decline in total phytoplankton biomass...