Research Topics
| E F SolomayerSummaryAffiliation: University of Heidelberg Country: Germany Publications
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Detail Information
Publications
Metastatic breast cancer: clinical course, prognosis and therapy related to the first site of metastasisE F Solomayer
Department of Obstetrics and Gynecology, University of Heidelberg, Germany
Breast Cancer Res Treat 59:271-8. 2000..The better prognosis of patients with bone metastases is not determined exclusively by hormone receptor status. The disease is significantly more stable in patients with first bone metastases than in those with first visceral metastases...
Prognostic relevance of cathepsin D detection in micrometastatic cells in the bone marrow of patients with primary breast cancerE F Solomayer
Department of Obstetrics and Gynaecology, University of Heidelberg, Germany
Breast Cancer Res Treat 49:145-54. 1998..The detection of cathepsin D on disseminated tumour cells characterises a subgroup of patients with a poorer prognosis who should undergo more aggressive adjuvant systemic therapy...
Time independence of the prognostic impact of tumor cell detection in the bone marrow of primary breast cancer patientsE F Solomayer
Department of Obstetrics and Gynecology, University of Tubingen, Schleichstrasse 4, 72076 Tubingen, Germany
Clin Cancer Res 7:4102-8. 2001..L. Mansi et al., Lancet, 354:197-202, 1999). We report data from 727 patients with a median follow-up period of 6.5 years...
Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow: a long-term follow-upI J Diel
Department of Gynecology and Obstetrics, University of Heidelberg, Heidelberg, Germany
Ann Oncol 19:2007-11. 2008..Adding oral clodronate to postoperative adjuvant breast cancer therapy significantly improves disease-free survival (DFS) and overall survival (OS). Long-term follow-up data from the prospective, randomized, controlled study are reported...
Bisphosphonates and the prevention of metastasis: first evidences from preclinical and clinical studiesI J Diel
Department of Obstetrics and Gynecology, University Hospital, Heidelberg, Germany
Cancer 88:3080-8. 2000..As well as having an apoptotic and antiproliferative effect on osteoclasts, bisphosphonates may exert a similar influence on macrophages and tumor cells...
Prognostic relevance of urokinase plasminogen activator detection in micrometastatic cells in the bone marrow of patients with primary breast cancerE F Solomayer
Department of Obstetrics and Gynaecology, University of Heidelberg, Germany
Br J Cancer 76:812-8. 1997..For the first time, it was possible to evaluate an important qualitative parameter involved in the process of breast cancer metastases...
Bisphosphonate-induced osteonecrosis of the jaw (ONJ): Incidence and risk factors in patients with breast cancer and gynecological malignanciesT Fehm
Department of Obstetrics and Gynecology, University of Tuebingen, Calwerstrasse 7, 72076 Tuebingen, Germany
Gynecol Oncol 112:605-9. 2009..The aim of this study was to describe the incidence and risk factors of ONJ in patients with breast cancer or gynecological malignancies receiving bisphosphonates (BP)...
Impaired bone microenvironment: correlation between bone density and presence of disseminated tumor cellsB Kraemer
Department of Obstetrics and Gynecology, University of Tuebingen, Calwerstrasse 7, 72076 Tuebingen, Germany
Anticancer Res 31:4423-8. 2011..An impaired bone microenvironment may lead to reduced bone density and osteoporosis affecting the BM as a homing site for DTCs. The bone mineral density (BMD) and its correlation to DTC in BM was evaluated...
