Ralf Smeets

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. ncbi Effect of chronic wound exudates and MMP-2/-9 inhibitor on angiogenesis in vitro
    Dietmar Ulrich
    Department of Plastic Surgery and Hand Surgery, Burn Center, University Hospital, Aachen University of Technology, Aachen, Germany
    Plast Reconstr Surg 116:539-45. 2005
  2. ncbi [Hydroxyapatite bone substitute (Ostim) in sinus floor elevation. Maxillary sinus floor augmentation: bone regeneration by means of a nanocrystalline in-phase hydroxyapatite (Ostim)]
    Ralf Smeets
    Klinik für Zahn, Mund, Kiefer und Plastische Gesichtschirurgie, Interdisziplinäres Zentrum für Klinische Forschung BIOMAT, Universitätsklinikum der RWTH Aachen
    Schweiz Monatsschr Zahnmed 118:203-12. 2008
  3. ncbi Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration
    Ralf Smeets
    Interdisciplinary Centre of Clinical Research BioMAT, University Hospital Aachen, D 52074 Aachen, Germany
    Int Wound J 5:195-203. 2008
  4. ncbi Analysis of trigeminal nerve disorders after oral and maxillofacial intervention
    Sareh Said Yekta
    Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Aachen University, Germany
    Head Face Med 6:24. 2010
  5. ncbi Impact of rhBMP-2 on regeneration of buccal alveolar defects during the osseointegration of transgingival inserted implants
    Ralf Smeets
    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Aachen, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:e3-e12. 2009
  6. ncbi A new biphasic osteoinductive calcium composite material with a negative Zeta potential for bone augmentation
    Ralf Smeets
    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Aachen, Germany
    Head Face Med 5:13. 2009
  7. ncbi Bioelectric impedance analysis and quality of life after body-contouring procedures in plastic surgery
    R Smeets
    Interdisciplinary Center for Clinical Research IZKF BIOMAT, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
    J Plast Reconstr Aesthet Surg 62:940-5. 2009
  8. ncbi Distant metastases of a squamous cell carcinoma of the tongue in peripheral skeletal muscles and adjacent soft tissues
    Ralf Smeets
    University Hospital Aachen, Department of Oral and Maxillofacial Surgery, Aachen, Germany
    Head Face Med 4:7. 2008
  9. ncbi Clinical evaluation of a biphasic calcium composite grafting material in the treatment of human periodontal intrabony defects: a 12-month randomized controlled clinical trial
    Jamal M Stein
    Department of Operative Dentistry, Periodontology, and Preventive Dentistry, University Hospital Aachen, Aachen, Germany
    J Periodontol 80:1774-82. 2009
  10. ncbi Verification of nerve integrity after surgical intervention using quantitative sensory testing
    Sareh Said-Yekta
    Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Aachen University, Aachen, Germany
    J Oral Maxillofac Surg 70:263-71. 2012

Detail Information

Publications30

  1. ncbi Effect of chronic wound exudates and MMP-2/-9 inhibitor on angiogenesis in vitro
    Dietmar Ulrich
    Department of Plastic Surgery and Hand Surgery, Burn Center, University Hospital, Aachen University of Technology, Aachen, Germany
    Plast Reconstr Surg 116:539-45. 2005
    ..In this study, the angiogenic effect of wound exudates from patients with venous insufficiency ulcers was examined in an in vitro angiogenesis model with and without synthetic MMP-2/-9 inhibitor...
  2. ncbi [Hydroxyapatite bone substitute (Ostim) in sinus floor elevation. Maxillary sinus floor augmentation: bone regeneration by means of a nanocrystalline in-phase hydroxyapatite (Ostim)]
    Ralf Smeets
    Klinik für Zahn, Mund, Kiefer und Plastische Gesichtschirurgie, Interdisziplinäres Zentrum für Klinische Forschung BIOMAT, Universitätsklinikum der RWTH Aachen
    Schweiz Monatsschr Zahnmed 118:203-12. 2008
    ..Furthermore, we even found osteoconductive bone regeneration under Ostim near the site of the loosened implant...
  3. ncbi Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration
    Ralf Smeets
    Interdisciplinary Centre of Clinical Research BioMAT, University Hospital Aachen, D 52074 Aachen, Germany
    Int Wound J 5:195-203. 2008
    ..The results show a significant and immediate reduction in protease activity in wound exudates from venous leg ulcers treated with ORC/collagen...
  4. ncbi Analysis of trigeminal nerve disorders after oral and maxillofacial intervention
    Sareh Said Yekta
    Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Aachen University, Germany
    Head Face Med 6:24. 2010
    ..Quantitative sensory testing (QST) is applied to evaluate somatosensory nerve fiber function in the spinal system. This study uses QST in patients with sensory dysfunctions after oral and maxillofacial surgery...
  5. ncbi Impact of rhBMP-2 on regeneration of buccal alveolar defects during the osseointegration of transgingival inserted implants
    Ralf Smeets
    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Aachen, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:e3-e12. 2009
    ..Therefore, we analyzed the impact of recombinant human bone morphogenic protein 2 (rhBMP-2) on the healing of large buccal alveolar defects during osseointegration of transgingivally inserted implants...
  6. ncbi A new biphasic osteoinductive calcium composite material with a negative Zeta potential for bone augmentation
    Ralf Smeets
    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Aachen, Germany
    Head Face Med 5:13. 2009
    ..The material demonstrated a negative surface charge (negative Zeta potential) which was found to be favorable for bone regeneration and osseointegration of dental implants...
  7. ncbi Bioelectric impedance analysis and quality of life after body-contouring procedures in plastic surgery
    R Smeets
    Interdisciplinary Center for Clinical Research IZKF BIOMAT, RWTH Aachen University, Pauwelsstrasse 30, D 52074 Aachen, Germany
    J Plast Reconstr Aesthet Surg 62:940-5. 2009
    ..The focus of inquiry was the change in body mass index (BMI) values and the correlation of these with health-related quality of life (HRQoL)...
  8. ncbi Distant metastases of a squamous cell carcinoma of the tongue in peripheral skeletal muscles and adjacent soft tissues
    Ralf Smeets
    University Hospital Aachen, Department of Oral and Maxillofacial Surgery, Aachen, Germany
    Head Face Med 4:7. 2008
    ..The final diagnosis was a T4N3M1(G3)(C3) SCC of the tongue with multiple distant thoracal, abdominal and intramuscular metastases. The survival expectancy was five weeks, and the patient finally deceased by cardiopulmonary complications...
  9. ncbi Clinical evaluation of a biphasic calcium composite grafting material in the treatment of human periodontal intrabony defects: a 12-month randomized controlled clinical trial
    Jamal M Stein
    Department of Operative Dentistry, Periodontology, and Preventive Dentistry, University Hospital Aachen, Aachen, Germany
    J Periodontol 80:1774-82. 2009
    ..The aim of this study was to compare the clinical outcome of a novel biphasic calcium composite (BCC) biomaterial versus autogenous bone spongiosa (ABS) or open flap debridement (OFD) for the treatment of intrabony periodontal defects...
  10. ncbi Verification of nerve integrity after surgical intervention using quantitative sensory testing
    Sareh Said-Yekta
    Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Aachen University, Aachen, Germany
    J Oral Maxillofac Surg 70:263-71. 2012
    ..Furthermore, this study determines the degree and duration of possible neuronal hyperexcitability due to local inflammatory trauma after oral surgery...
  11. ncbi In vitro study of adhesive polymethylmethacrylate bone cement bonding to cortical bone in maxillofacial surgery
    Ralf Smeets
    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Aachen, Germany
    J Oral Maxillofac Surg 68:3028-33. 2010
    ..In the present experimental study, the strength of this adhesive bond and its resistance to hydrolysis were investigated...
  12. ncbi Gender specific quality of life in patients with oral squamous cell carcinomas
    Oliver Maciejewski
    University Hospital Aachen, Department of Oral and Maxillofacial Surgery, Aachen, Germany
    Head Face Med 6:21. 2010
    ..The factors gender, age, nicotine consumption, and tumour stage were taken into consideration...
  13. ncbi A novel hemostatic delivery device for thrombin: biodegradable poly(D,L-lactide-co-glycolide) 50:50 microspheres
    Ralf Smeets
    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Aachen, Germany
    J Biomed Mater Res A 96:177-85. 2011
    ..With this study, a new biodegradable hemostyptic device could be verified and established for a potentially safe and locally controlled thrombin release to manage postsurgical hemorrhage in patients undergoing anticoagulant therapy...
  14. ncbi Clinical periodontal and microbiologic parameters in patients with acute myocardial infarction
    Jamal M Stein
    Department of Operative Dentistry, Perdiodontology, and Dentistry, University Hospital Aachen, Aachen, Germany
    J Periodontol 80:1581-9. 2009
    ..The aim of this study was to evaluate the impact of clinical periodontal parameters and the presence of periodontal pathogens in patients with acute myocardial infarction (AMI)...
  15. ncbi The influence of bisphosphonates on human osteoblast migration and integrin aVb3/tenascin C gene expression in vitro
    Felix P Koch
    Department of Oral and Maxillofacial Surgery, University medical centre of Johannes Gutenberg University Mainz, Augustusplatz 2, 55131 Mainz, Germany
    Head Face Med 7:4. 2011
    ..Therefore, the influence on adhesion and migration of human osteoblasts (hOB) after bisphosphonate therapy has been investigated by morphologic as well as gene expression methods...
  16. ncbi Assessment of trigeminal nerve functions by quantitative sensory testing in patients and healthy volunteers
    Sareh Said Yekta
    Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Aachen University, Aachen, Germany
    J Oral Maxillofac Surg 68:2437-51. 2010
    ..Orofacial sensory dysfunction plays an important role in oral and maxillofacial surgery. Quantitative sensory testing (QST) is a psychophysical approach to evaluate thermal and mechanical somatosensation...
  17. ncbi In vitro proliferation of human osteogenic cells in presence of different commercial bone substitute materials combined with enamel matrix derivatives
    Christoph Reichert
    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Aachen, Germany
    Head Face Med 5:23. 2009
    ..In regenerative dentistry, these bone grafting materials are routinely combined with enamel matrix derivatives (EMD) in order to additionally enhance tissue regeneration...
  18. ncbi The impact of bisphosphonates on the osteoblast proliferation and Collagen gene expression in vitro
    Felix Peter Koch
    Department of Oral and Maxillofacial Surgery, University Hospital Aachen, Aachen, Germany
    Head Face Med 6:12. 2010
    ..Furthermore, the gene expression of the extracellular matrix protein collagen type I was evaluated. Nitrogen-containing and non-nitrogen-containing bisphosphonates have been compared on gene expression levels...
  19. ncbi Skeletal stability following bilateral sagittal split osteotomy (BSSO) with and without condylar positioning device
    Marcus Gerressen
    Department of Oral, Maxillofacial and Plastic Facial Surgery, Universitätsklinikum der RWTH Aachen, Aachen, Germany
    J Oral Maxillofac Surg 65:1297-302. 2007
    ....
  20. ncbi Influence of bisphosphonates on the osteoblast RANKL and OPG gene expression in vitro
    Felix Peter Koch
    Department of Oral and Maxillofacial Surgery, University medical centre of Johannes Gutenberg University Mainz, Mainz, Germany
    Clin Oral Investig 16:79-86. 2012
    ..Interestingly, clodronate might have little influence on osteoblast/osteoclast interaction with respect to OPG and RANKL gene expression...
  21. ncbi Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique
    Markus Lindner
    Department of Dental Materials and Biomaterials Research, University Hospital RWTH Aachen, Germany
    J Biomed Mater Res A 97:466-71. 2011
    ..We conclude that SLM presents a new possibility to manufacture individual biodegradable implants made of ?-TCP/PDLLA...
  22. ncbi Evaluation of functional nerve recovery with Visual-SSI--a novel computerized approach for the assessment of the static sciatic index (SSI)
    Ahmet Bozkurt
    Department of Plastic, Reconstructive, and Hand Surgery, Burn Center, University Hospital RWTH Aachen, Pauwelsstrasse 30, Aachen, Germany
    J Neurosci Methods 170:117-22. 2008
    ..05). The present method combines efficiency (simplicity of use, rapid and economical setup) with accurate and precise quantification of the functional regeneration in the sciatic nerve lesion model of the rat...
  23. ncbi The impact of defined polyglycolide scaffold structure on the proliferation of gingival fibroblasts in vitro: a pilot study
    Frank Bäumchen
    Department of Conservative Dentistry, Periodontology, and Preventive Dentistry, University Hospital Aachen, Aachen, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:505-13. 2009
    ..The aim of this study was to examine the proliferation behavior of human gingival fibroblasts on polyglycolic acid (PGA) fleeces with various structural characteristics...
  24. ncbi The role of the composite interleukin-1 genotype in the association between periodontitis and acute myocardial infarction
    Jamal M Stein
    Department of Operative Dentistry and Periodontology, University Hospital Aachen, Aachen, Germany
    J Periodontol 80:1095-102. 2009
    ..The aim of this study was to evaluate the impact of the composite IL-1 genotype (allele 2 at IL-1A -889 and IL-1B +3954) in the association between acute myocardial infarction (AMI) and periodontitis...
  25. ncbi Intraoperative cone-beam computed tomography in oral and maxillofacial surgery using a C-arm prototype: first clinical experiences after treatment of zygomaticomaxillary complex fractures
    Philipp Pohlenz
    Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Oral Maxillofac Surg 67:515-21. 2009
    ..To describe the first clinical applications of intraoperative cone-beam computed tomography with an integrated flat-panel detector in oral and maxillofacial surgery after surgical treatment of zygomaticomaxillary complex fractures..
  26. ncbi Human leukocyte antigen polymorphism in chronic and aggressive periodontitis among Caucasians: a meta-analysis
    Jamal M Stein
    Department of Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital RWTH, Aachen, Germany
    J Clin Periodontol 35:183-92. 2008
    ..Because associations are inconsistent, we conducted a systematic literature review and a meta-analysis focusing on Caucasian case-control studies...
  27. ncbi [High-grade osteosarcoma of the maxillary sinus. A case report]
    Marcus Gerressen
    Klinik für Zahn, Mund, Kiefer und Plastische Gesichtschirurgie des Universitätsklinikums der RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Germany
    Mund Kiefer Gesichtschir 10:347-52. 2006
    ..Compared to osteosarcoma of the remaining skeleton (SOS) JOS metastasizes relatively rarely and relatively late. It differs significantly from SOS in its biological behaviour...
  28. ncbi Neural differentiation potential of human bone marrow-derived mesenchymal stromal cells: misleading marker gene expression
    Katrin Montzka
    Department of Neurology, RWTH Aachen University, Aachen, Germany
    BMC Neurosci 10:16. 2009
    ....
  29. ncbi A new adhesive technique for internal fixation in midfacial surgery
    Kira Endres
    University Hospital Aachen, Dental Prosthetics Clinic, Medical Materials R and D Laboratory, Pauwelsstrasse 30, 52057 Aachen, Germany
    Biomed Eng Online 7:16. 2008
    ..In order to achieve the adhesive bonding of bone cement to cortical bone in the viscerocranium, an amphiphilic bone bonding agent was created, analogous to the dentin bonding agents currently on the market...
  30. ncbi Fetuin-A (AHSG) prevents extraosseous calcification induced by uraemia and phosphate challenge in mice
    Ralf Westenfeld
    Department of Nephrology and Clinical Immunology, University Hospital Aachen, Pauwelsstrasse 30, D 52057 Aachen, Germany
    Nephrol Dial Transplant 22:1537-46. 2007
    ..Chronic kidney disease (CKD) is associated with vascular and tissue calcification. The extent of vascular calcification has been identified as an independent risk factor of cardiovascular death in patients on haemodialysis...