Research Topics
Species | F PietruckSummaryAffiliation: University of Essen Country: Germany Publications
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Detail Information
Publications
Digital fluorescence imaging of organic cation transport in freshly isolated rat proximal tubulesFrank Pietruck
Department of Nephrology, School of Medicine, University Hospital, Essen, Germany
Drug Metab Dispos 34:339-42. 2006....
Efficacy and safety of enteric-coated mycophenolate sodium in renal transplant patients with diabetes mellitus: post hoc analyses from three clinical trialsFrank Pietruck
Department of Nephrology, University Hospital Essen, Essen, Germany
Clin Transplant 21:117-25. 2007..Moreover, diabetic patients can apparently be safely converted from MMF to EC-MPS. More data from prospective studies are needed to fully judge the efficacy and safety profile of EC-MPS in the diabetic transplant population...
Conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium in stable maintenance renal transplant patients: pooled results from three international, multicenter studiesF Pietruck
University Hospital Essen, Department of Nephrology, Essen, Germany
Transplant Proc 39:103-8. 2007..Enteric-coated mycophenolate sodium (EC-MPS; myfortic) has been developed with the intention of improving mycophenolic acid-related GI tolerability...
Rosiglitazone is a safe and effective treatment option of new-onset diabetes mellitus after renal transplantationFrank Pietruck
Department of Nephrology, University Hospital Essen, Germany
Transpl Int 18:483-6. 2005..There were no changes either in serum creatinine concentrations, or cyclosporine and tacrolimus blood levels respectively. Treatment with rosiglitazone appears to be safe and effective in patients with NODM after renal transplantation...
Evaluation of the effect of candesartan cilexetil on the steady-state pharmacokinetics of tacrolimus in renal transplant patientsFrank Pietruck
Department of Nephrology and Hypertension, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany
Biopharm Drug Dispos 26:135-41. 2005..Tacrolimus is widely used as an immunosuppressant following renal transplantation. The aim of this study was to evaluate the effect of multiple doses of candesartan cilexetil on the steady-state pharmacokinetics of tacrolimus...
Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopyM Horbelt
Department of Nephrology, School of Medicine, University Hospital, Essen, Germany
Kidney Int 72:422-9. 2007..Intracellular uptake of ASP(+) into proximal tubules was significantly reduced by cimetidine. Our studies show that organic cation transport of the kidney can be visualized in vivo by two-photon laser scanning microscopy...
Nephrotoxicity of iso-osmolar versus low-osmolar contrast media is equal in low risk patientsT Feldkamp
Department of Nephrology and Hypertension, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany
Clin Nephrol 66:322-30. 2006..Therefore, we compared the nephrotoxicity of isoosmotic contrast media iodixanol with the low-osmotic contrast media iopromid in patients receiving contrast media during coronary angiography...
Effect of quercetin on hypoxic injury in freshly isolated rat proximal tubulesFrank Pietruck
, , 45122, Essen, Germany
J Lab Clin Med 142:106-12. 2003..These results demonstrate the potency of the bioflavonoid quercetin in protecting proximal tubules from hypoxic injury, which is independent of tubular energy metabolism and may be related to the inhibition of lipid peroxidation...
Procalcitonin for accurate detection of infection in haemodialysisS Herget-Rosenthal
Division of Nephrology, University Hospital, University of Essen, D-45122 Essen, Germany
Nephrol Dial Transplant 16:975-9. 2001..High-flux membranes substantially decrease PCT. When utilizing high flux membranes, serum PCT concentrations should be determined prior to the start of HD...
Sotrastaurin, a novel small molecule inhibiting protein kinase C: first clinical results in renal-transplant recipientsK Budde
Department of Nephrology, Charite University, Berlin, Germany
Am J Transplant 10:571-81. 2010..The initial sotrastaurin + tacrolimus regimen was efficacious and well tolerated but the postconversion sotrastaurin + MPA regimen showed inadequate efficacy. Longer-term evaluation of sotrastaurin + tacrolimus is warranted...
[Acute renal failure--an review]A Kribben
,
Dtsch Med Wochenschr 128:1231-6. 2003
ATP protects, by way of receptor-mediated mechanisms, against hypoxia-induced injury in renal proximal tubulesAndreas Kribben
Department of Nephrology and Hypertension, University Hospital Essen, Germany
J Lab Clin Med 141:67-73. 2003..The data indicate that the protective effect of ATP is mediated by P(2) receptors...
Prognostic value of tubular proteinuria and enzymuria in nonoliguric acute tubular necrosisStefan Herget-Rosenthal
Department of Nephrology, University Hospital, Essen, Germany
Clin Chem 50:552-8. 2004..We prospectively studied the diagnostic accuracy of the urinary excretion of low-molecular-weight proteins and enzymes as predictors of a need for RRT in ATN...
Early detection of acute renal failure by serum cystatin CStefan Herget-Rosenthal
Department of Nephrology, Thoracic and Cardiovascular Surgery, University Hospital, Essen, Germany
Kidney Int 66:1115-22. 2004..However, serum creatinine, the standard marker to detect ARF, demonstrates major limitations. We prospectively evaluated whether serum cystatin C detected ARF earlier than serum creatinine...
Differential tissue distribution of the Invs gene product inversinJens Nürnberger
Department of Nephrology and Hypertension, University Hospital of Essen, Hufelandstrasse 55, 45122 Essen, Germany
Cell Tissue Res 323:147-55. 2006..Further studies are required to understand the way in which mutations in the Invs gene lead to the multi-organ pathology of inv mouse and human nephronophthisis...
OKT3 therapy in addition to tacrolimus is associated with improved long-term function in patients with steroid refractory renal allograft rejectionDaniel Patschan
Department of Nephrology, School of Medicine, University of Duisburg-Essen, Essen, Germany
Nephron Clin Pract 103:c94-9. 2006..CONCLUSION: Our data indicate a reasonable graft survival in steroid refractory renal allograft rejection using tacrolimus. OKT3 treatment in addition to tacrolimus therapy may be beneficial for long-term allograft survival...
Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantationM Kohnle
Department of Nephrology, School of Medicine, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany
Am J Transplant 6:205-8. 2006..Ezetimibe seems to be an effective therapy for uncontrolled hypercholesterolemia in renal transplant patients when combined with high-dose statin therapy...
Serum cystatin C--a superior marker of rapidly reduced glomerular filtration after uninephrectomy in kidney donors compared to creatinineS Herget-Rosenthal
Department of Nephrology, University Hospital, Essen, University Duisburg Essen, Germany
Clin Nephrol 64:41-6. 2005..Serum creatinine, the conventional GFR marker, has major limitations. We prospectively evaluated whether serum cystatin C detected a rapid GFR decrease earlier and more accurately than serum creatinine...
The impact of living-related kidney transplantation on the donor's lifeJens Reimer
Department of Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, and Department of Nephrology, School of Medicine, University Hospital Essen, Essen, Germany
Transplantation 81:1268-73. 2006..This study was conducted to illuminate the decision making-process and consequences of LDKT on family life, the financial and occupational situation. Moreover, quality of life (QOL) and mental distress were explored...
Isoagglutinin titre adsorption: breaking the barrier in major AB0-incompatible organ transplantationBenjamin Wilde
Department of Nephrology, University Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
Transfus Apher Sci 41:45-8. 2009..This protocol has excellent short-term and long-term graft survival as well as function although recipient anti-A/B titres after transplantation return to pre-surgical levels within months after transplantation...
Free androgen index is superior to total testosterone for short-term assessment of the gonadal axis after renal transplantationWalter Reinhardt
Department of Nephrology, School of Medicine, University of Duisburg-Essen, Essen, Germany
Horm Res 64:248-52. 2005..CONCLUSION: Measurement of the free androgen index is superior to total testosterone for assessment of the pituitary-gonadal axis in the first weeks after renal transplantation...
Bone disease after renal transplantationUlrich Kunzendorf
Nephrol Dial Transplant 23:450-8. 2008
