Charlotte Marie Niemeyer

Summary

Affiliation: University of Freiburg
Country: Germany

Publications

  1. ncbi Juvenile myelomonocytic leukemia
    Charlotte Marie Niemeyer
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Curr Treat Options Oncol 4:203-10. 2003
  2. ncbi Is granulocyte colony-stimulating factor therapy a risk factor for myelodysplasia/leukemia in patients with congenital neutropenia?
    Charlotte M Niemeyer
    Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
    Haematologica 90:2-3. 2005
  3. ncbi Refractory anemia in childhood: a retrospective analysis of 67 patients with particular reference to monosomy 7
    Gabriela Kardos
    Division of Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Mathildenstrasse 1, 79106 Freiburg, Germany
    Blood 102:1997-2003. 2003
  4. ncbi Juvenile myelomonocytic leukemia
    Charlotte Marie Niemeyer
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Curr Oncol Rep 5:510-5. 2003
  5. ncbi Pediatric myelodysplastic syndromes
    Charlotte Marie Niemeyer
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Curr Treat Options Oncol 6:209-14. 2005
  6. ncbi EGFR inhibition using gefitinib is not active in neuroblastoma cell lines
    Jochen Rossler
    Department of Pediatrics and Adolescent Medicine, University Hospital of Freiburg, 79106 Freiburg, Germany
    Anticancer Res 29:1327-33. 2009
  7. ncbi Successful treatment of refractory chronic disseminated candidiasis after prolonged administration of caspofungin in a child with acute myeloid leukemia
    Udo Kontny
    Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany
    Pediatr Blood Cancer 49:360-2. 2007
  8. ncbi Chimaerism analyses and subsequent immunological intervention after stem cell transplantation in patients with juvenile myelomonocytic leukaemia
    Ayami Yoshimi
    Department of Paediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Br J Haematol 129:542-9. 2005
  9. ncbi Lymphangiogenesis and its regulation in human neuroblastoma
    Jeanette Lagodny
    Division of Pediatric Hematology Oncology, Department of Pediatrics and Adolescent Medicine, Mathilsdenstr 1, 79106 Freiburg, Germany
    Biochem Biophys Res Commun 352:571-7. 2007
  10. ncbi Alveolar rhabdomyosarcoma mimicking lymphoma with bone marrow involvement
    Christof Andreas Hanke
    Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Mathildenstrasse 1, 79106, Freiburg, Germany
    Eur J Pediatr 166:505-6. 2007

Collaborators

Detail Information

Publications23

  1. ncbi Juvenile myelomonocytic leukemia
    Charlotte Marie Niemeyer
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Curr Treat Options Oncol 4:203-10. 2003
    ....
  2. ncbi Is granulocyte colony-stimulating factor therapy a risk factor for myelodysplasia/leukemia in patients with congenital neutropenia?
    Charlotte M Niemeyer
    Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
    Haematologica 90:2-3. 2005
  3. ncbi Refractory anemia in childhood: a retrospective analysis of 67 patients with particular reference to monosomy 7
    Gabriela Kardos
    Division of Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Mathildenstrasse 1, 79106 Freiburg, Germany
    Blood 102:1997-2003. 2003
    ..Recommendations for best treatment options for children with other chromosomal abnormalities or normal karyotype may have to await results of prospective clinical trials...
  4. ncbi Juvenile myelomonocytic leukemia
    Charlotte Marie Niemeyer
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Curr Oncol Rep 5:510-5. 2003
    ....
  5. ncbi Pediatric myelodysplastic syndromes
    Charlotte Marie Niemeyer
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Curr Treat Options Oncol 6:209-14. 2005
    ..Unraveling some of the underlying genetic factors predisposing to MDS at a young age may give important insights into leukemogenesis in the elderly...
  6. ncbi EGFR inhibition using gefitinib is not active in neuroblastoma cell lines
    Jochen Rossler
    Department of Pediatrics and Adolescent Medicine, University Hospital of Freiburg, 79106 Freiburg, Germany
    Anticancer Res 29:1327-33. 2009
    ..Inhibition of the epidermal growth factor receptor (EGFR), using a tyrosine kinase inhibitor such as gefitinib, was suggested to be a new treatment approach for neuroblastoma...
  7. ncbi Successful treatment of refractory chronic disseminated candidiasis after prolonged administration of caspofungin in a child with acute myeloid leukemia
    Udo Kontny
    Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany
    Pediatr Blood Cancer 49:360-2. 2007
    ..Therapy was given for a total of 12 months and had no attributable adverse effects. This approach resulted in successful treatment of refractory CDC with caspofungin...
  8. ncbi Chimaerism analyses and subsequent immunological intervention after stem cell transplantation in patients with juvenile myelomonocytic leukaemia
    Ayami Yoshimi
    Department of Paediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Br J Haematol 129:542-9. 2005
    ..In conclusion, serial quantitative chimaerism studies can identify patients with i-MC who are at high risk for relapse of JMML. Immediate withdrawal of IST is advised in these patients...
  9. ncbi Lymphangiogenesis and its regulation in human neuroblastoma
    Jeanette Lagodny
    Division of Pediatric Hematology Oncology, Department of Pediatrics and Adolescent Medicine, Mathilsdenstr 1, 79106 Freiburg, Germany
    Biochem Biophys Res Commun 352:571-7. 2007
    ..We conclude that lymphangiogenesis is involved in NB biology and that siRNA directed against VEGF-C may have a future role in anti-lymphangiogenic strategies in NB...
  10. ncbi Alveolar rhabdomyosarcoma mimicking lymphoma with bone marrow involvement
    Christof Andreas Hanke
    Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Mathildenstrasse 1, 79106, Freiburg, Germany
    Eur J Pediatr 166:505-6. 2007
  11. ncbi Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia: molecular classification and treatment options
    Charlotte Marie Niemeyer
    Department of Paediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
    Br J Haematol 140:610-24. 2008
    ..Research on genetic conditions predisposing to MDS in young age, such as inherited syndromes with bone marrow failure, may present important insights into MDS pathogenesis...
  12. ncbi Myelodysplastic features in an infant with cystic fibrosis presenting with anaemia, oedema and failure to thrive
    Christian Peter Kratz
    Department of Paediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
    Eur J Pediatr 164:56-7. 2005
  13. ncbi Lethal proliferation of erythroid precursors in a neonate with a germline PTPN11 mutation
    Christian Peter Kratz
    Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
    Eur J Pediatr 165:182-5. 2006
    ..In conclusion, this case report suggests that congenital myeloproliferative disorders in association with germline PTPN11 mutations may affect the erythroid lineage...
  14. ncbi Effect of STI-571 (imatinib mesylate) in combination with retinoic acid and gamma-irradiation on viability of neuroblastoma cells
    Jochen Rossler
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Hospital of Freiburg, Germany
    Biochem Biophys Res Commun 342:1405-12. 2006
    ..Treatment of NB with STI-571 in combination with 9-cis RA might be a therapeutic strategy for patients in consolidation therapy who have completed gamma-irradiation therapy...
  15. ncbi Evaluating systemic prednisone therapy for proliferating haemangioma in infancy
    Jochen Rossler
    Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany
    Eur J Pediatr 167:813-5. 2008
    ..For 93% of the children, this protocol was successful in reducing the size of the haemangioma by more than 25% after 2 weeks of treatment. Side effects were moderate and reversible after cessation of therapy...
  16. ncbi Myelodysplastic syndrome in children and adolescents
    Charlotte M Niemeyer
    Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Freiburg, Freiburg, Germany
    Semin Hematol 45:60-70. 2008
    ..Allogeneic hematopoietic stem cell transplantation (HSCT) from a matched related or suitable unrelated donor is the choice for most children with MDS and can rescue a large proportion of patients...
  17. ncbi AKAP12, a gene with tumour suppressor properties, is a target of promoter DNA methylation in childhood myeloid malignancies
    Christian Flotho
    Division of Paediatric Haematology Oncology, University of Freiburg, Freiburg, Germany
    Br J Haematol 138:644-50. 2007
    ..While AKAP12 function has not been previously linked to leukaemogenesis, our results raise the possibility that epigenetic silencing of AKAP12 is involved in myeloid malignancies...
  18. ncbi Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity
    Andrej Lissat
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Albert Ludwigs University, Mathildenstrasse 1, 79106 Freiburg, Germany
    Am J Pathol 170:1917-30. 2007
    ..In conclusion, our data provide a rationale for the inclusion of interferon-gamma in upcoming clinical trials with TRAIL...
  19. ncbi Essential versus reactive thrombocythemia in children: retrospective analyses of 12 cases
    Abeer Abd El Moneim
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Germany
    Pediatr Blood Cancer 49:52-5. 2007
    ..Essential thrombocythemia (ET) rarely occurs in the pediatric population and little is known about the clinical course and the molecular characteristics...
  20. ncbi Uniparental disomy at chromosome 11p15.5 followed by HRAS mutations in embryonal rhabdomyosarcoma: lessons from Costello syndrome
    Christian P Kratz
    Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
    Hum Mol Genet 16:374-9. 2007
    ..These data implicate that in sporadic ERMS, UPD at 11p15.5 is not driven by HRAS mutations and that imbalances at 11p15.5 and HRAS mutations represent independent but cooperating events during ERMS development...
  21. ncbi Stem cell transplantation for paroxysmal nocturnal haemoglobinuria in childhood
    Christian Flotho
    Children's Hospital, University of Freiburg, Freiburg, Germany
    Br J Haematol 118:124-7. 2002
    ..Indications and techniques of SCT in childhood PNH are discussed and an overview of the literature is given...
  22. ncbi Expression analysis of alpha-NAC and ANX2 in juvenile myelomonocytic leukemia using SMART polymerase chain reaction and "virtual Northern" hybridization
    Klaus Hämmerle
    Division of Pediatric Hematology Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, University Children s Hospital, Germany
    Cancer Genet Cytogenet 142:149-52. 2003
    ..We found no consistent pattern of differential expression between patients and healthy donors. We conclude that aberrant regulation of NACA or ANX2 does not play a relevant role in JMML pathogenesis...
  23. ncbi Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia
    Charlotte M Niemeyer
    Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
    Nat Genet 42:794-800. 2010
    ....