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Species | Dieter NaberSummaryAffiliation: University of Hamburg Country: Germany Publications
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Publications
Anticonvulsants in the treatment of aggression in the demented elderly: an updateBenedikt Amann
Benito Menni, CASM, Research Unit, CIBERSAM, St Boi de Llobregat, Barcelona, Spain
Clin Pract Epidemiol Ment Health 5:14. 2009..At least 50% of the dramatically growing number of patients with dementia exerts aggressive and agitated symptoms during the course of clinical progression, particularly at moderate clinical severity...
The CATIE and CUtLASS studies in schizophrenia: results and implications for cliniciansDieter Naber
Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
CNS Drugs 23:649-59. 2009..There is no single antipsychotic that is best for every schizophrenia patient, as individual responses differ markedly. For successfully individualized treatment, a multitude of antipsychotic options are needed...
Tools for measuring clinical effectivenessDieter Naber
Department of Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany
Eur Neuropsychopharmacol 14:S435-44. 2004..If this approach to evaluating treatment outcomes is adopted, clinicians will be better placed to differentiate therapeutic interventions on the basis of clinical effectiveness...
Good tolerability equals good results: the patient's perspectiveD Naber
Hospital of Psychiatry and Psychotherapy, University of Hamburg, Martinistrasse 52, D 20247 Hamburg, Germany
Eur Neuropsychopharmacol 11:S391-6. 2001....
Improvement of schizophrenic patients' subjective well-being under atypical antipsychotic drugsD Naber
Universitäts Krankenhaus Hamburg Eppendorf, Clinic for Psychiatry and Psychotherapy, Martinistrasse 52, 20246 Hamburg, Germany
Schizophr Res 50:79-88. 2001..It is concluded that the assessment of subjective well-being under antipsychotic treatment provides an independent outcome measure which is relevant to compliance...
[Subjective well-being under antipsychotic treatment and its meaning for compliance and course of disease]Dieter Naber
Universitatsklinikum Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie
Psychiatr Prax 31:S230-2. 2004....
Olanzapine pamoate for the treatment of schizophreniaDieter Naber
Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
Expert Opin Pharmacother 12:627-33. 2011..Psychiatrists should reconsider their negative attitudes toward long-acting or depot antipsychotics and should offer this administration to the majority of patients, not only to a negatively selected population...
[Pro and contra: basic precedence of atypical neuroleptics]Dieter Naber
,
Psychiatr Prax 32:163-6. 2005
Randomized double blind comparison of olanzapine vs. clozapine on subjective well-being and clinical outcome in patients with schizophreniaD Naber
Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
Acta Psychiatr Scand 111:106-15. 2005..This randomized double-blind multicenter trial evaluated the effects of olanzapine vs. clozapine on subjective well-being, quality of life (QOL) and clinical outcome...
Aripiprazole: a new atypical antipsychotic with a different pharmacological mechanismDieter Naber
Department of Psychiatry and Psychotherapy, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg 20246, Germany
Prog Neuropsychopharmacol Biol Psychiatry 28:1213-9. 2004..However, only post-marketing experience will show whether the positive results of these controlled trials can be replicated in everyday practice...
Long-term phase of schizophrenia: impact of atypical agentsD Naber
Universitat Hamburg, Germany
Int Clin Psychopharmacol 15:S11-4. 2000..This is associated with alleviation of negative symptoms and cognitive deficits, benefits which are not seen with traditional agents and which increase the likelihood of successful rehabilitation...
Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: valid predictors of symptomatic response and remission?Rebecca Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
World J Biol Psychiatry 11:729-38. 2010..To examine quality of life and subjective well-being as predictors of symptomatic treatment outcome...
Attitude towards adherence in patients with schizophrenia at dischargeRebecca Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
J Psychiatr Res 43:1294-301. 2009....
Long-term patterns of subjective wellbeing in schizophrenia: cluster, predictors of cluster affiliation, and their relation to recovery criteria in 2842 patients followed over 3 yearsMartin Lambert
Psychosis Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Germany
Schizophr Res 107:165-72. 2009....
Characterization of the facial expression of emotions in schizophrenia patients: preliminary findings with a new electromyography methodKarsten Wolf
Department of Psychiatry and Psychotherapy, University Hospital of Hamburg, Germany
Can J Psychiatry 51:335-41. 2006..We investigated facial expression of emotions (FEE) in schizophrenia patients, using an improved and highly selective facial electromyography (EMG) method, and we examined the correlation between FEE and psychopathology...
Does clinical judgment of baseline severity and changes in psychopathology depend on the patient population? Results of a CGI and PANSS linking analysis in a naturalistic studyRebecca Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Munich, Germany
J Clin Psychopharmacol 30:726-31. 2010..Furthermore, these linking results were compared with those derived from randomized controlled trials to examine if the baseline severity might influence the linking results...
Subjective wellbeing under quetiapine treatment: effect of diagnosis, mood state, and anxietyMartin Lambert
Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
Schizophr Res 110:72-9. 2009..To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR...
Differential 3-year effects of first- versus second-generation antipsychotics on subjective well-being in schizophrenia using marginal structural modelsMartin Lambert
Psychosis Centre, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Centre Hamburg Eppendorf, Germany
J Clin Psychopharmacol 31:226-30. 2011..This study examined the differential effects of first- (FGAs) versus second-generation antipsychotics (SGAs) on subjective well-being in patients with schizophrenia...
Validation of a Clinical Global Impression Scale for Aggression (CGI-A) in a sample of 558 psychiatric patientsChristian G Huber
Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Germany
Schizophr Res 100:342-8. 2008..Clinical management of aggression depends on the availability of easily administrable measurements allowing reliable evaluation. The present study's aim is to validate a Clinical Global Impression-Severity of Aggression scale (CGI-A)...
Association of subjective well-being, symptoms, and side effects with compliance after 12 months of treatment in schizophreniaAnne Karow
Center for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
J Clin Psychiatry 68:75-80. 2007....
Physical and mental health in severe opioid-dependent patients within a randomized controlled maintenance treatment trialJens Reimer
Centre for Interdisciplinary Addiction Research, University of Hamburg, Hamburg, Germany
Addiction 106:1647-55. 2011..To evaluate physical and mental health and compare treatment outcomes in opiate-dependent patients substituted either with heroin or methadone...
Management of incomplete remission and treatment resistance in first-episode psychosisMartin Lambert
University Medical Centre Hamburg Eppendorf, Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, Martinistreet 52, D 20246 Hamburg, Germany
Expert Opin Pharmacother 9:2039-51. 2008..Incomplete remission and treatment resistance are common even in first-episode psychosis patients...
[Subjective view of positive symptoms and quality of life in patients with schizophrenia]Anne Karow
Zentrum fur Psychosoziale Medizin, Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf, Hamburg
Psychiatr Prax 35:286-93. 2008..The aim of the study was the investigation of positive symptoms and quality of life from the subjective perspective of patients with schizophrenia...
Remission in schizophrenia: validity, frequency, predictors, and patients' perspective 5 years laterMartin Lambert
Psychosis Centre, Department of Psychiatry and Psychotherapy, Center for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, German
Dialogues Clin Neurosci 12:393-407. 2010..Future research should therefore search for criteria of these dimensions and test whether the RSWG remission criteria consistently predict a "good" outcome with respect to functioning and quality of life...
Assertive community treatment as part of integrated care versus standard care: a 12-month trial in patients with first- and multiple-episode schizophrenia spectrum disorders treated with quetiapine immediate release (ACCESS trial)Martin Lambert
Psychosis Centre, Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
J Clin Psychiatry 71:1313-23. 2010....
Establishing remission and good clinical functioning in schizophrenia: predictors of best outcome with long-term risperidone long-acting injectable treatmentM Lambert
Psychosis Centre, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf Hamburg, Martinistreet 52, 20246 Hamburg, Germany
Eur Psychiatry 25:220-9. 2010..To measure symptomatic and functional remission in patients treated with risperidone long-acting injectable (RLAI)...
Objective and subjective efficacy as well as tolerability of olanzapine in the acute treatment of 120 patients with schizophrenia spectrum disordersMartin Lambert
Department for Psychiatry and Psychotherapy, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
Int Clin Psychopharmacol 18:251-60. 2003..The results underline the need of Phase IV studies for the assessment of clinical antipsychotic efficacy and tolerability...
Effectiveness, tolerability, and safety of ziprasidone in patients with schizophrenia or schizoaffective disorder: results of a multi-centre observational trialDuerten Kudla
Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Eur Psychiatry 22:195-202. 2007..Secondary objectives included quality of life, subjective well-being, tolerability, and safety...
The impact of subjective well-being under neuroleptic treatment on compliance and remissionWalter de Millas
Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Dialogues Clin Neurosci 8:131-6. 2006..The data strongly suggest that a systematic evaluation of the patient's perspective of antipsychotic treatment is meaningful and necessary to increase compliance, functional outcome, and long-term prognosis...
Comorbidity of schizophrenia and galactosemia: effective clozapine treatment with weight gainChristian Haasen
Department of Psychiary and Psychotherapy, University Hospital Eppendorf, Hamburg, Germany
Int Clin Psychopharmacol 18:113-5. 2003....
How to treat the untreated: effectiveness of a self-help metacognitive training program (myMCT) for obsessive-compulsive disorderSteffen Moritz
University Medical Center Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany
Dialogues Clin Neurosci 12:209-20. 2010..63), particularly for obsessions (d= .69). Medium to strong differences emerged for the OCI-R (d = .70) and the BDI-SF (d = .50). The investigation provides the first evidence for the effectiveness of the myMCT for OCD...
Predictors of relapse in the year after hospital discharge among patients with schizophreniaRebecca Schennach
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstreet 7, 80336 Munich, Germany
Psychiatr Serv 63:87-90. 2012..Relapse and its predictors were examined among patients with schizophrenia in the year after hospital discharge...
Early onset of treatment effects with oral risperidoneThomas J Raedler
Department of Psychiatry, University Medical Center Hamburg Eppendorf, Martinistr, 52, 20246 Hamburg, Germany
BMC Psychiatry 7:4. 2007..However, recent studies have challenged this concept. We therefore performed an analysis of the onset of antipsychotic treatment effects in a sample of acutely decompensated patients with schizophrenia...
Prediction of remission as a combination of symptomatic and functional remission and adequate subjective well-being in 2960 patients with schizophreniaMartin Lambert
Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
J Clin Psychiatry 67:1690-7. 2006....
Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disordersRebecca Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Schizophr Res 113:210-7. 2009..To assess criteria and to identify predictive factors for functional outcome. The criteria should cover all domains proposed by the Remission in Schizophrenia Working Group...
'Hyper-priming' in thought-disordered schizophrenic patientsS Moritz
, , Hamburg, Germany
Psychol Med 31:221-9. 2001....
Current issues in schizophrenia: overview of patient acceptability, functioning capacity and quality of lifeMartin Lambert
Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany
CNS Drugs 18:5-17; discussion 41-3. 2004..Ideally, an atypical drug which is known not to have a negative effect on attention, affect or motivation should be chosen...
[On subjective meaning of psychoses. Construction, validation and first application of a new questionnaire--the SuSi-Project (Hamburg)]Thomas Bock
Universitätsklinik Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Martinistrasse 52, 20246 Hamburg, Germany
Psychiatr Prax 37:285-91. 2010..A new questionnaire to assess subjective meaning in psychosis (SuSi) will be presented...
Diagnostic validity of ICD-10 personality dimensions: a multitrait-multimethod analysis of two self-report questionnaires and a structured interviewKatrin Schroeder
Department of Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
Psychopathology 43:110-20. 2010..There is growing evidence that the validity of diagnostic methods for personality disorders (PD) may be insufficient. Although the ICD-10 classification system is widely used, there is little data concerning its validity for diagnosing PD...
Incomplete remission and treatment resistance in first-episode psychosis: definition, prevalence and predictorsChristian G Huber
University Medical Centre Hamburg Eppendorf, Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, Martinistreet 52, D 20246 Hamburg, Germany
Expert Opin Pharmacother 9:2027-38. 2008..Different definitions for these terms have been used in psychiatric research, making generalized statements about the prevalence and predictors of treatment resistance difficult...
[Outpatient prescription of atypical antipsychotics for schizophrenic patients after discharge from hospital treatment]Ingo Schafer
Universitätsklinik Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Hamburg, Germany
Psychiatr Prax 31:74-7. 2004..However, global statistics of prescriptions are difficult to interpret. To get data of the current practice, 132 patients treated with atypical antipsychotics in a university clinic were followed-up one year later...
No deficits in nonverbal memory, metamemory and internal as well as external source memory in obsessive-compulsive disorder (OCD)Steffen Moritz
University Medical Center Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany
Behav Res Ther 47:308-15. 2009..We claim that research should move forward from the mere study of objective impairment to the assessment of cognitive performance in conjunction with personality traits such as inflated responsibility...
Outcome of suicidal patients with schizophrenia: results from a naturalistic studyR Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Acta Psychiatr Scand 121:359-70. 2010..Purpose was to assess suicidality before and at the time of admission in patients with schizophrenia and compare outcome differences...
Cost-effectiveness of 12-month therapeutic assertive community treatment as part of integrated care versus standard care in patients with schizophrenia treated with quetiapine immediate release (access trial)Anne Karow
Psychosis Centre, Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
J Clin Psychiatry 73:e402-8. 2012..ACT was specifically developed for patients with schizophrenia, delivered by psychosis experts highly trained in respective psychotherapies, and embedded into an integrated care system...
Influence of atypical neuroleptics on executive functioning in patients with schizophrenia: a randomized, double-blind comparison of olanzapine vs. clozapineStefan Bender
Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Germany
Int J Neuropsychopharmacol 9:135-45. 2006..However, Stroop reaction time improved with olanzapine while clozapine had a stronger effect on improving negative symptoms, thus suggestive of a differential drug effect...
Adjunctive use of reboxetine in schizophreniaThomas J Raedler
University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Martini str 52, 20246 Hamburg, Germany
Eur Psychiatry 19:366-9. 2004..We sought to study the efficacy and tolerability of the adjunctive use of reboxetine in a cohort of schizophrenic patients with prominent depressive or negative symptoms...
Subjective cognitive dysfunction in first-episode and chronic schizophrenic patientsS Moritz
Clinic for Psychiatry and Psychotherapy, University Clinic Hamburg-Eppendorf, Hamburg, Germany
Compr Psychiatry 42:213-6. 2001..In marked contrast to a Kraepelinian view of schizophrenia, the present data confirm previous studies conducted with objective neuropsychological tests that schizophrenia is a neurodevelopmental rather than a neurodegenerative disorder...
[Atypical neuroleptics in the treatment of aggression and hostility in schizophrenic patients]P Briken
Zentrum fur Psychosoziale Medizin, Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf, Germany
Fortschr Neurol Psychiatr 70:139-44. 2002..In persistent aggression clozapin shows the best specific results. Typical depot neuroleptics should be considered in cases when medication compliance is a problem...
Brief Psychiatric Rating Scale - Excited Component (BPRS-EC) and neuropsychological dysfunction predict aggression, suicidality, and involuntary treatment in first-episode psychosisChristian G Huber
Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Centre Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
Schizophr Res 134:273-8. 2012..Although there are studies on prevalence and clinical predictors of these conditions, little is known on the influence of psychopathology and neuropsychological dysfunction...
Everyday memory functioning in obsessive- compulsive disorderLena Jelinek
Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
J Int Neuropsychol Soc 12:746-9. 2006..1). According to norm values, memory performance was unimpaired in most OCD patients. The present findings further challenge a broad account of the "memory deficit" hypothesis of OCD and compulsive checking, respectively...
Attitudes of patients with schizophrenia and depression to psychiatric research: a study in seven European countriesIngo Schafer
Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
Soc Psychiatry Psychiatr Epidemiol 46:159-65. 2011..Relatively few studies have examined how patients with schizophrenia and depression view psychiatric research and what influences their readiness to participate...
Memory and attention performance in psychiatric patients: lack of correspondence between clinician-rated and patient-rated functioning with neuropsychological test resultsSteffen Moritz
University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany
J Int Neuropsychol Soc 10:623-33. 2004..Reasons for decreased sensitivity of self-reported and clinician-assessed neurocognitive functioning are discussed...
Depression in Alzheimer's disease might be associated with apolipoprotein E epsilon 4 allele frequency in women but not in menThomas Müller-Thomsen
Department of Psychiatry and Psychotherapy, University of Hamburg, Germany
Dement Geriatr Cogn Disord 14:59-63. 2002..This effect remained stable in stepwise regression analysis when depression as the dependent variable was tested against the independent variables age, age of onset, duration of disease, cognitive status and years of school education...
[Treatment resistant schizophrenia, residual subtype: symptom improvement after additional treatment with amisulpride]Karsten Wolf
Universitatsklinikum Hamburg Eppendorf, Klinik und Poliklinik fur Psychiatrie und Psychotherapie
Psychiatr Prax 33:42-4. 2006..Therapy resistant, severe residual schizophrenia poses major challenges for the psychiatric pharmacological treatment...
Neurocognitive performance in first-episode and chronic schizophrenic patientsSteffen Moritz
University Hospital of Hamburg, Hospital for Psychiatry and Psychotherapy, Germany
Eur Arch Psychiatry Clin Neurosci 252:33-7. 2002..It is suggested that neuropsychological disturbances occur early in schizophrenia and do not worsen in the course beyond age-related decrement. Possible reasons why previous research has produced contradictory findings are discussed...
["Anti-stigma campaign from below" at schools--experience of the initiative "Irre menschlich Hamburg e.V."]Thomas Bock
Klinik fur Psychiatrie und Psychotherapie, Universitätsklinik Hamburg Eppendorf
Psychiatr Prax 30:402-8. 2003..The more health politically based motives of the anti-stigma work have meanwhile been completed by educational justifications. This way of open meeting is also being discussed as a completion to the symptom based early diagnosis...
Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulprideM Lambert
Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy of the University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
Acta Psychiatr Scand 115:106-13. 2007..Studies of subjective wellbeing (SW) in schizophrenia have missed to define and to assess rate and predictors of SW response (SW-res) and SW remission (SW-rem)...
Impact of present and past antipsychotic side effects on attitude toward typical antipsychotic treatment and adherenceM Lambert
Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University of Hamburg, Martini Street 52, 20246 Hamburg, Germany
Eur Psychiatry 19:415-22. 2004....
Early- and delayed antipsychotic response and prediction of outcome in 528 severely impaired patients with schizophrenia treated with amisulprideM Lambert
Psychosis Early Detection and Intervention Centre PEDIC, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf
Pharmacopsychiatry 42:277-83. 2009..Limiting factors of these studies include the restriction on symptomatic outcome, the inclusion of mostly moderately ill patients, and the use of various antipsychotics...
Subjective well-being and initial dysphoric reaction under antipsychotic drugs - concepts, measurement and clinical relevanceM Lambert
Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany
Pharmacopsychiatry 36:S181-90. 2003..This article reviews existing literature in order to approach relevant questions for pharmacotherapy...
[Sex-specific differences in schizophrenia]T J Rädler
Universitatsklinikum Hamburg Eppendorf, Klinik und Poliklinik fur Psychiatrie und Psychotherapie
MMW Fortschr Med 149:32-4. 2007..Women who undergo pharmacological therapy of schizophrenia have a higher drug serum level at the same dose and a higher risk of developing certain side effects, such as hyperprolactinaemia...
The dilemma of insight into illness in schizophrenia: self- and expert-rated insight and quality of lifeA Karow
Department for Psychiatry und Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
Eur Arch Psychiatry Clin Neurosci 258:152-9. 2008..It was hypothesised that patients with greater self- and expert-rated insight into illness report lower QOL compared to patients with poor insight...
[Identification of possible cognizance parameters of "mimic disintegration" in schizophrenia using facial electromyography]K Wolf
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg Eppendorf Deutschland
Nervenarzt 76:1103-4, 1105-8. 2005..We suggest further examination of the two mimic disintegration signs regarding other emotions, necessarily including more facial muscles in the testing...
Treatment of severe agitation with olanzapine in 166 patients with schizophrenia, schizoaffective, or bipolar I disorderM Lambert
Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Centre, Hamburg Eppendorf, Germany
Pharmacopsychiatry 41:182-9. 2008..Agitation is a common phenomenon in schizophrenia or acute mania. Because of the inability of patients to give informed consent in such situations, data from consenting studies are limited...
[Atypical antipsychotics in therapy refractory schizophrenia]I Schafer
Klinik für Psychiatrie und Psychoterapie der Universitätsklinik Hamburg Eppendorf
Nervenarzt 75:79-91. 2004..Case studies also indicate the efficacy of combining different atypical antipsychotics, but no systematic research on this issue has been done so far...
Rates and predictors of remission and recovery during 3 years in 392 never-treated patients with schizophreniaM Lambert
Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Acta Psychiatr Scand 118:220-9. 2008..Few studies have prospectively examined remission and recovery as well as their predictors in schizophrenia simultaneously. Aims of the study were to identify remission and recovery rates as well as their predictors in schizophrenia...
Olanzapine vs. other antipsychotics in actual out-patient settings: six months tolerability results from the European Schizophrenia Out-patient Health Outcomes studyM Lambert
Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
Acta Psychiatr Scand 111:232-43. 2005..The European Schizophrenia Out-patient Health Outcomes study is an observational study investigating treatment in schizophrenia. We report treatment-emergent adverse events during the first 6 months of treatment...
Cognitive dysfunction at baseline predicts symptomatic 1-year outcome in first-episode schizophrenicsS Moritz
Universitäts Krankenhaus Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Hamburg, Deutschland
Psychopathology 33:48-51. 2000..005). It is suggested that the exploration and treatment of neuropsychological deficits in schizophrenia is of great clinical importance with regard to its impact on both functional and symptomatic outcome in schizophrenia...
[Open studies in comparison to controlled studies in testing of neuroleptics]F G Pajonk
Klinik fur Psychiatrie und Psychotherapie, Universitätskrankenhaus Hamburg Eppendorf
Fortschr Neurol Psychiatr 68:313-20. 2000..Aim of this study was to investigate if results of an open or double-blind approach differ and hereby to gain information about the validity of open trials...
[Treatment oriented to subjective well- being rather than symptom amelioration "at all costs"--paradigm change in treatment with antipsychotics]A Karow
Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf
MMW Fortschr Med 147:44-5. 2005..With this approach, the physician-patient relationship, compliance and the long-term prognosis can all be appreciably improved...
[Conversion from typical to atypical neuroleptics. Guidelines for ambulatory and inpatient treatment]M Lambert
Klinik für Psychiatrie und Psychotherapie der Universität Hamburg
Nervenarzt 71:859-75. 2000..The present article addresses guidelines for the conversion from conventional to atypical neuroleptics in inpatient and outpatient settings...
What would the patient choose? Subjective comparison of atypical and typical neurolepticsA Karow
University Hospital Hamburg Eppendorf, Department of Psychiatry und Psychotherapy
Pharmacopsychiatry 39:47-51. 2006..The aim of this study was to compare atypical and typical neuroleptics from the patient's perspective...
Comparison of olanzapine and risperidone in 367 first-episode patients with non-affective or affective psychosis: results of an open retrospective medical record studyM Lambert
Department of Psychiatry and Psychotherapy, University of Hamburg, Martini Street 52, 20246 Hamburg, Germany
Pharmacopsychiatry 38:206-13. 2005..Previous studies comparing olanzapine (OLZ) and risperidone (RIS) have tended to focus on multiple-episode patients, with no studies examining their comparative efficacy in a non-selective sample of first-episode psychosis...
Neuropsychological correlates of schizophrenic syndromes in patients treated with atypical neurolepticsS Moritz
Universitäts Krankenhaus Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Martinistrasse 52, D 20246, Hamburg, Germany
Eur Psychiatry 16:354-61. 2001..Previous findings reporting correlations between negative symptomatology and neurocognition may have been confounded by the adverse consequences of typical neuroleptics...
Gender-specific effects in the treatment of acute schizophrenia with risperidoneT J Raedler
Department of Psychiatry, University Hospital Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Pharmacopsychiatry 39:171-4. 2006..We have now reanalysed the clinical data to assess the effects of gender on treatment and outcome...
The impact of substance use disorders on clinical outcome in 643 patients with first-episode psychosisM Lambert
Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, Psychosis Early Detection and Intervention Centre PEDIC, University Hospital Hamburg Eppendorf, Hamburg, Germany
Acta Psychiatr Scand 112:141-8. 2005..The main aim of the present study was to assess the impact of baseline SUD and course of SUD on remission of positive symptoms...
Negative priming in schizophrenia: effects of masking and prime presentation timeS Moritz
Universitäts Krankenhaus Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Martinistrasse 52, D 20246 Hamburg, Germany
Schizophr Res 48:291-9. 2001..Results strongly suggest that reduced negative priming in schizophrenics may not be due to reduced cognitive inhibition but mirrors perceptual deficits...
Enhanced semantic priming in thought-disordered schizophrenic patients using a word pronunciation taskS Moritz
Universitäts Krankenhaus Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Martinistrasse 52, D 20246 Hamburg, Germany
Schizophr Res 48:301-5. 2001..Results were not moderated by sociodemographic background variables, psychomotor slowing and psychopathological symptoms other than thought disorder...
Comparing the efficacy of atypical antipsychotics in open uncontrolled versus double-blind controlled trials in schizophreniaFrank Gerald Pajonk
Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
Psychopharmacology (Berl) 162:29-36. 2002..The aim of this study was to investigate whether results of open and double-blind approaches differ and thereby gain information about the validity of open trials...
Risperidone in the treatment of acute schizophreniaThomas J Raedler
Department of Psychiatry, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
J Clin Psychopharmacol 24:335-8. 2004..To evaluate the efficacy of the atypical antipsychotic risperidone, we conducted an open-label observational study among admissions to a secure unit...
The facial pattern of disgust, appetence, excited joy and relaxed joy: an improved facial EMG studyKarsten Wolf
Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
Scand J Psychol 46:403-9. 2005..Our findings indicate the possibility to explore the entire emotion system successfully through a state-of-the-art psychophysiological method like our EMG device...
Psychopharmacological treatment of aggression in schizophrenic patientsT Brieden
Department of Psychiatry and Psychotherapy, Hamburg-Eppendorf University Hospital, Germany
Pharmacopsychiatry 35:83-9. 2002..In addition, we will briefly present studies and case reports concerning the treatment of aggression in other psychiatric patients...
Subjective well-being and quality of life under atypical antipsychotic treatmentA Karow
University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Martinistrasse 52, 20246 Hamburg, Germany
Psychopharmacology (Berl) 162:3-10. 2002..Furthermore, the benefit of introducing atypical antipsychotics early in the course of illness and their particular benefit in combination with rehabilitative non-pharmacological treatment is discussed...
Suicides and suicide attempts in emergency medicineFrank Gerald Pajonk
Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
Crisis 23:68-73. 2002..This investigation presents a first evaluation of the complete emergency protocols from a major German city focusing on suicide and parasuicide...
Heroin-assisted treatment for opioid dependence: randomised controlled trialChristian Haasen
Centre for Interdisciplinary Addiction Research, Department of Psychiatry, University Medical Centre Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
Br J Psychiatry 191:55-62. 2007..Heroin-assisted treatment has been found to be effective for people with severe opioid dependence who are not interested in or do poorly on methadone maintenance...
Switching to amisulpride due to hepatic complicationsOktay Yagdiran
University Hospital Eppendorf, Clinic for Psychiatry and Psychotherapy, Martinistr. 52, 20246, Hamburg, Germany
Eur Psychiatry 17:170-1. 2002
CSF-tau, CSF-Abeta1-42, ApoE-genotype and clinical parameters in the diagnosis of Alzheimer's disease: combination of CSF-tau and MMSE yields highest sensitivity and specificityS Ganzer
Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
J Neural Transm 110:1149-60. 2003..CSF-Abeta1-42 showed no additional benefit in discriminating patients from controls but might be useful for tracking the severity of the disease...
Trait dissociation affects the behavioral response to cholecystokinin tetrapeptide in healthy manMichael Kellner
Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, D 20246, Hamburg, Germany
Psychiatry Res 111:93-6. 2002..Trait dissociation should be assessed in further behavioral challenge studies as a potentially important covariate...
Rationale and baseline characteristics of PREVENT: a second-generation intervention trial in subjects at-risk (prodromal) of developing first-episode psychosis evaluating cognitive behavior therapy, aripiprazole, and placebo for the prevention of psychosiAndreas Bechdolf
Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
Schizophr Bull 37:S111-21. 2011..When the final results of the trial are available, PREVENT will substantially expand the current limited evidence base for best clinical practice in people at-risk (prodromal) of first-episode psychosis...
Leptin: a modulator of alcohol craving?F Kiefer
Department of Psychiatry and Psychotherapy, University Hospital Hamburg, Hamburg, Germany
Biol Psychiatry 49:782-7. 2001..No correlations of craving with cortisol and BMI were observed. CONCLUSIONS: We suggest that leptin may modulate withdrawal-induced craving in alcoholic subjects...
The relationship between quality of life and clinical efficacy from a randomized trial comparing olanzapine and ziprasidoneGlenn A Phillips
Eli Lilly and Company, Indianapolis, IN 46285, USA
J Clin Psychiatry 67:1397-403. 2006..To examine treatment-specific changes in health-related quality of life (QOL) among patients with schizophrenia and to assess the association between clinical and QOL improvement...
Olanzapine versus ziprasidone: results of a 28-week double-blind study in patients with schizophreniaAlan Breier
Lilly Research Laboratories, DC 2128, 1 Corporate Plaza, Indianapolis, IN 46285, USA
Am J Psychiatry 162:1879-87. 2005..The efficacy and safety of olanzapine were compared with those of ziprasidone...
Constructing an Index for the Subjective Well-being Under Neuroleptics scale (SWN), short form: applying structural equation modeling for testing reliability and validity of the indexPeter Schmidt
Institut für Politikwissenschaften, FB 03 Sozial und Kulturwissenschaften, Justus Liebig Universitat Giessen, Karl Glöckner Strasse 21 E, 35394 Giessen, Germany
Qual Life Res 15:1191-202. 2006..The application of SEM showed no appreciable loss of validity of this index...
Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disordersMarkus Jager
Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
Eur Arch Psychiatry Clin Neurosci 257:47-53. 2007..The aim was to investigate the hypothesis that patients with first episode schizophrenic disorders have a more favorable treatment response than those with multiple episodes...
Three-year antipsychotic effectiveness in the outpatient care of schizophrenia: observational versus randomized studies resultsJosep Maria Haro
San Joan de Déu Serveis de Salut Mental, Fundació Sant Joan de Déu, Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain
Eur Neuropsychopharmacol 17:235-44. 2007..Antipsychotic maintenance in SOHO was higher than the results of previous randomized studies...
Is quality of life among minimally symptomatic patients with schizophrenia better following withdrawal or continuation of antipsychotic treatment?Charles M Beasley
Lilly Research Laboratories, Eli Lilly and Co, Indianapolis, IN 46285, USA
J Clin Psychopharmacol 26:40-4. 2006....
The influence of olanzapine versus risperidone on facial expression of emotions in schizophrenia--preliminary results of a facial electromyogram studyKarsten Wolf
J Clin Psychopharmacol 25:278-81. 2005
Comorbid somatic illnesses in patients with severe mental disorders: clinical, policy, and research challengesW Wolfgang Fleischhacker
Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
J Clin Psychiatry 69:514-9. 2008....
Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment responseMarkus Jager
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Psychiatry Res 158:297-305. 2008..Therefore, the hypothesis that depressive symptoms are predictive of a favorable treatment response was not supported by the present study...
Efficacy and safety of risperidone in the treatment of elderly patients suffering from organic brain disease (organic brain syndrome): results from a double-blind, randomized, placebo-controlled clinical trialDieter Naber
Psychopharmacology (Berl) 191:1027-9. 2007
