Research Topics
| Thomas LueckeSummaryAffiliation: University of Heidelberg Country: Germany Publications
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Detail Information
Publications
Oleic acid vs saline solution lung lavage-induced acute lung injury: effects on lung morphology, pressure-volume relationships, and response to positive end-expiratory pressureThomas Luecke
Department of Anesthesiology and Critical Care Medicine, University Hospital of Mannheim, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Theodor Kutzer Ufer, Germany
Chest 130:392-401. 2006....- Predictors of mortality in ARDS patients referred to a tertiary care centre: a pilot studyThomas Luecke
Department of Anesthesiology and Critical Care Medicine, University of Heidelberg, Faculty of Clinical Medicine, Hospital of Mannheim, Germany
Eur J Anaesthesiol 23:403-10. 2006.... - Clinical review: Positive end-expiratory pressure and cardiac outputThomas Luecke
Department of Anesthesiology and Critical Care Medicine, University Hospital of Mannheim, Germany
Crit Care 9:607-21. 2005..Finally, the hemodynamic consequences of PEEP in patients with heart failure, chronic obstructive pulmonary disease and acute respiratory distress syndrome are discussed... - [Haemodynamic effects of mechanical ventilation]T Luecke
Klinik fur Anaesthesiologie und operative Intensivmedizin, Universitatsklinikum Mannheim, Mannheim, Deutschland
Anaesthesist 56:1242-51. 2007.... - Setting mean airway pressure during high-frequency oscillatory ventilation according to the static pressure--volume curve in surfactant-deficient lung injury: a computed tomography studyThomas Luecke
Department of Anesthesiology and Intensive Care Medicine, University Hospital of Mannheim, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Germany
Anesthesiology 99:1313-22. 2003.... - PEEP decreases atelectasis and extravascular lung water but not lung tissue volume in surfactant-washout lung injuryThomas Luecke
Department of Anesthesiology and Critical Care Medicine, Faculty of Clinical Medicine, University Hospital, Theodor Kutzer Ufer, 68167, Mannheim, Germany
Intensive Care Med 29:2026-33. 2003..To examine the effects of positive end-expiratory pressure (PEEP) on extravascular lung water (EVLW), lung tissue, and lung volume... - Assessment of cardiac preload and left ventricular function under increasing levels of positive end-expiratory pressureThomas Luecke
Department of Anesthesiology and Intensive Care Medicine, Faculty of Clinical Medicine, University Hospital of Mannheim, Mannheim, Germany
Intensive Care Med 30:119-26. 2004..The validity of these parameters was tested by means of correlation with left ventricular end-diastolic volume (LVEDV), the true cardiac preload... - An increase of abdominal pressure increases pulmonary edema in oleic acid-induced lung injuryMichael Quintel
, , Mannheim, Mannheim, Germany
Am J Respir Crit Care Med 169:534-41. 2004..We conclude that in OA-injured lung, the increase of IAP increases the amount of edema... - End-expiratory lung volumes and density distribution patterns during partial liquid ventilation in healthy and oleic acid-injured sheep: a computed tomography studyThomas Luecke
Department of Anesthesiology and Intensive Care Medicine, University Hospital of Mannheim, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Mannheim, Germany
Crit Care Med 31:2190-7. 2003.... - Effects of positive end-expiratory pressure on respiratory function and hemodynamics in patients with acute respiratory failure with and without intra-abdominal hypertension: a pilot studyJoerg Krebs
Department of Anesthesiology and Critical Care Medicine, University Hospital Mannheim, Faculty of Medicine, University of Heidelberg, Mannheim, Germany, Theodor Kutzer Ufer, Mannheim, 68165, Germany
Crit Care 13:R160. 2009.... - Computed tomography scan assessment of lung volume and recruitment during high-frequency oscillatory ventilationThomas Luecke
Department of Anesthesiology, University Hospital of Mannheim, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Germany
Crit Care Med 33:S155-62. 2005..CONCLUSION: CT is a valuable tool to quantify recruitment and overinflation during HFOV. Additional studies are needed to better characterize the specific effects of HFOV on lung volume and morphology... - Open lung approach associated with high-frequency oscillatory or low tidal volume mechanical ventilation improves respiratory function and minimizes lung injury in healthy and injured ratsJoerg Krebs
Department of Anaesthesiology and Critical Care Medicine, University Hospital Mannheim, Faculty of Medicine, University of Heidelberg, Theodor Kutzer Ufer, 1 3, 68165 Mannheim, Germany
Crit Care 14:R183. 2010.... - Respiratory and haemodynamic changes during decremental open lung positive end-expiratory pressure titration in patients with acute respiratory distress syndromeChristian Gernoth
Department of Anesthesiology and Critical Care Medicine, University Hospital Mannheim, Faculty of Medicine, University of Heidelberg, Theodor Kutzer Ufer, 68165 Mannheim, Germany
Crit Care 13:R59. 2009.... - Time course of lung inflammatory and fibrogenic responses during protective mechanical ventilation in healthy ratsJoerg Krebs
Department of Anaesthesiology and Critical Care Medicine, University Hospital Mannheim, Faculty of Medicine, University of Heidelberg, Theodor Kutzer Ufer 1 3, 68165 Mannheim, Germany
Respir Physiol Neurobiol 178:323-8. 2011..In conclusion, OL-MV in healthy rats yielded overinflation after 6 h even though respiratory elastance and gas-exchange were preserved for up to 12 h... - Severe traumatic brain injury complicated by status asthmaticus: favorable neurological outcome despite excessive hypercapniaHendric Mittelstaedt
Departments of Anesthesiology and Critical Care, University Hospital of Mannheim, University of Heidelberg, Germany
J Trauma 60:888-90. 2006 - One liver for four children: first clinical series of liver cell transplantation for severe neonatal urea cycle defectsJochen Meyburg
Department of General Pediatrics, University Children s Hospital, Heidelberg, Germany
Transplantation 87:636-41. 2009..They are promising target diseases for liver cell transplantation (LCT), which may be a less invasive alternative or supplementation to orthotopic liver transplantation... - Effects of patient-triggered automatic switching between mandatory and supported ventilation in the postoperative weaning periodH Roth
Department of Anaesthesiology and Intensive Care, University Hospital of Mannheim, Faculty of Clinical Medicine, University of Heidelberg, Germany
Intensive Care Med 27:47-51. 2001.... - The use of the excimer laser-assisted anastomosis technique alleviates neuroanesthesia during cerebral high-flow revascularizationElke Muench
Department of Anesthesiology, Klinikum Mannheim, University of Heidelberg, Mannheim, Germany
J Neurosurg Anesthesiol 19:273-9. 2007.... - Semifluorinated alkanes--a new class of excipients suitable for pulmonary drug deliveryC Tsagogiorgas
Dept of Anaesthesiology and Intensive Care Medicine, University Medical Center Mannheim, Mannheim, Germany
Eur J Pharm Biopharm 76:75-82. 2010..Unlike Perfluorocarbons (PFCs), SFAs have the potential to dissolve several lipophilic or water-insoluble substances. This makes them possibly suitable as new excipients for inhalative liquid drug carrier systems... - Effects of end-inspiratory and end-expiratory pressures on alveolar recruitment and derecruitment in saline-washout-induced lung injury -- a computed tomography studyT Luecke
Department of Anesthesiology and Intensive Care, University Hospital of Mannheim, Faculty of Clinical Medicine, University of Heidelberg, Germany
Acta Anaesthesiol Scand 48:82-92. 2004..CONCLUSION: Limiting peak inspiratory pressure and VT does not impair alveolar recruitment or promote derecruitment when using sufficient levels of PEEP... - Lung imaging for titration of mechanical ventilationThomas Luecke
Department of Anesthesiology and Critical Care Medicine, University Hospital Mannheim, Faculty of Medicine, University of Heidelberg, Mannheim, Germany
Curr Opin Anaesthesiol 25:131-40. 2012..This review aims to present the major findings of recent studies on lung imaging... - [Critical illness polyneuropathy and myopathy. Pathogenesis and diagnostic]Markus Alb
Klinik fur Anasthesiologie und Operative Intensivmedizin, Universitatsklinikum Mannheim, Germany
Anasthesiol Intensivmed Notfallmed Schmerzther 42:250-8. 2007..Neurological and electrophysiological examinations as well as muscle biopsies if myopathy is of concern may help to characterize and identify polyneuropathy and myopathy... - Pulmonary gas distribution during ventilation with different inspiratory flow patterns in experimental lung injury -- a computed tomography studyH Roth
Department of Anesthesiology and Critical Care, University Hospital of Mannheim, Faculty of Clinical Medicine, University of Heidelberg, Heidelberg, Germany
Acta Anaesthesiol Scand 48:851-61. 2004.... - Randomized clinical trial of perianal surgery performed under spinal saddle block versus total intravenous anaesthesiaM D Schmittner
Department of Anaesthesiology and Surgical Intensive Care Medicine, Mannheim, Germany
Br J Surg 97:12-20. 2010..The aim of this randomized clinical trial was to determine whether spinal saddle block (SSB) is superior to total intravenous anaesthesia (TIVA) in perianal surgery...