Christian Lottner

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi Combined chemotherapeutic and photodynamic treatment on human bladder cells by hematoporphyrin-platinum(II) conjugates
    Christian Lottner
    Institute of Inorganic Chemistry, University of Regensburg, Regensburg 93040, Germany
    Cancer Lett 203:171-80. 2004
  2. ncbi Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells
    Christian Lottner
    Institute of Inorganic Chemistry, University of Regensburg, 93040 Regensburg, Germany
    Cancer Lett 215:167-77. 2004
  3. ncbi Soluble tetraarylporphyrin-platinum conjugates as cytotoxic and phototoxic antitumor agents
    Christian Lottner
    , , 93040 Regensburg, Germany
    J Med Chem 45:2079-89. 2002
  4. ncbi Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity
    Christian Lottner
    , , 93040 Regensburg, Germany
    J Med Chem 45:2064-78. 2002
  5. ncbi Simultaneous detection of HER2/neu gene amplification and protein overexpression in paraffin-embedded breast cancer
    Christian Lottner
    Institute of Pathology, University of Regensburg, 93042 Regensburg, Germany
    J Pathol 205:577-84. 2005

Detail Information

Publications5

  1. ncbi Combined chemotherapeutic and photodynamic treatment on human bladder cells by hematoporphyrin-platinum(II) conjugates
    Christian Lottner
    Institute of Inorganic Chemistry, University of Regensburg, Regensburg 93040, Germany
    Cancer Lett 203:171-80. 2004
    ....
  2. ncbi Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells
    Christian Lottner
    Institute of Inorganic Chemistry, University of Regensburg, 93040 Regensburg, Germany
    Cancer Lett 215:167-77. 2004
    ..DNA platination in J82 and UROtsa cells was higher by PEG-HPPt than by cisplatin, whereas there was no significant difference between the two cell lines...
  3. ncbi Soluble tetraarylporphyrin-platinum conjugates as cytotoxic and phototoxic antitumor agents
    Christian Lottner
    , , 93040 Regensburg, Germany
    J Med Chem 45:2079-89. 2002
    ..The most active compounds were among the tetraarylporphyrin-platinum conjugates bearing the diammine and (RR/SS)-trans-1,2-diaminocyclohexane ligands...
  4. ncbi Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity
    Christian Lottner
    , , 93040 Regensburg, Germany
    J Med Chem 45:2064-78. 2002
    ....
  5. ncbi Simultaneous detection of HER2/neu gene amplification and protein overexpression in paraffin-embedded breast cancer
    Christian Lottner
    Institute of Pathology, University of Regensburg, 93042 Regensburg, Germany
    J Pathol 205:577-84. 2005
    ..3%) had HER2/neu gene amplification without protein overexpression. The main advantage of this novel approach is that polysomy, aneuploidy, gene amplification, and protein content can be analysed simultaneously in the same cell...