Research Topics
| H C KortingSummaryAffiliation: University of Munich Country: Germany Publications
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Publications
Current topical and systemic approaches to treatment of rosaceaH C Korting
Department of Dermatology and Allergology, Ludwig Maximilians Universitat, Munich, Germany
J Eur Acad Dermatol Venereol 23:876-82. 2009....
Topical fluticasone propionate: intervention and maintenance treatment options of atopic dermatitis based on a high therapeutic indexH C Korting
Department of Dermatology and Allergology, Ludwig Maximilians Universitat, Munich, Germany
J Eur Acad Dermatol Venereol 26:133-40. 2012..g. prednicarbate, methylprednisolone aceponate and mometasone furoate. However, randomized controlled trials do not only support conventional intervention but also innovative maintenance treatment...
Medical devices in dermatology: topical semi-solid formulations for the treatment of skin diseasesHans Christian Korting
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
J Dtsch Dermatol Ges 10:103-9. 2012..A variety of evidence-based medical devices for several dermatological indications are presented here...
One week terbinafine 1% cream (Lamisil) once daily is effective in the treatment of interdigital tinea pedis: a vehicle controlled study. LAS-INT-06 Study GroupH C Korting
Department of Dermatology, Ludwig Maximilians University, Munich, Germany
Med Mycol 39:335-40. 2001..The short duration of treatment needed to achieve mycological cure has important implications for patient compliance and for control of infection within the community...
[Acne vulgaris. Role of cosmetics]H C Korting
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Ludwig Maximilians Universität München, Frauenlobstr 9 11, 80337 München
Hautarzt 61:126-31. 2010..At least some of these ingredients underscore the concept of evidence-based cosmetics. In contrast, the problem of acne lesions caused by comedogenic ingredients in cosmetics today is negligible...
Tetracycline actions relevant to rosacea treatmentH C Korting
Department of Dermatology and Allergology, Ludwig Maximilians Universitat, Munich, Germany
Skin Pharmacol Physiol 22:287-94. 2009..The role of the saprophytic mite Demodex folliculorum remains to be clarified. Additional studies are necessary to further elucidate how tetracyclines work in rosacea treatment...
Management of minor acute cutaneous wounds: importance of wound healing in a moist environmentH C Korting
Department of Dermatology and Allergology, Ludwig Maximilians Universitat, Munich, Germany
J Eur Acad Dermatol Venereol 25:130-7. 2011....
[Management of acne vulgaris: focus on clindamycin and zinc]H C Korting
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Ludwig Maximilians Universität München, Frauenlobstrasse 9 11, 80337, Munchen
Hautarzt 60:42-7. 2009..Moreover, a recent study has shown that patients themselves prefer a complex of zinc acetate/clindamycin phosphate...
The significance of itraconazole for treatment of fungal infections of skin, nails and mucous membranesHans Christian Korting
Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany
J Dtsch Dermatol Ges 7:11-9, 11-20. 2009..In the treatment of oropharyngeal candidiasis, candidiasis of the skin and vulvovaginal candidiasis, itraconazole and fluconazole are the preferred treatment options in cases in which topical therapy has proven unsuccessful...
[Maintenance treatment and early intervention--the new paradigm in the management of atopic eczema]Hans Christian Korting
,
J Dtsch Dermatol Ges 3:519-23. 2005
Comparable efficacy and safety of various topical formulations of terbinafine in tinea pedis irrespective of the treatment regimen: results of a meta-analysisHans Christian Korting
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Munich, Germany
Am J Clin Dermatol 8:357-64. 2007....
Resistance of liposomal sunscreen formulations against plain water as well as salt water exposure and perspirationH C Korting
Department of Dermatology and Allergology, Ludwig Maximilian University, Frauenlobstrasse 9 11, Munich, Germany
Skin Pharmacol Physiol 24:36-43. 2011....
[Comparison of activity of different topical corticosteroid creams and ointments using a vasoconstriction assay: superiority of hydrocortisone butyrate over hydrocortisone]Hans Christian Korting
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Universitat Munchen, Germany
J Dtsch Dermatol Ges 3:348-53. 2005..Topical corticosteroids are the treatment of choice for numerous inflammatory or hyperproliferative skin diseases. The vasoconstriction assay is suitable to determinate corticosteroid activity...
Efficacy and tolerability of pale sulfonated shale oil cream 4% in the treatment of mild to moderate atopic eczema in children: a multicentre, randomized vehicle-controlled trialH C Korting
Department of Dermatology and Allergology, Ludwig Maximilians Universitat, Munich, Germany
J Eur Acad Dermatol Venereol 24:1176-82. 2010....
Safety and efficacy of fluticasone propionate in the topical treatment of skin diseasesA Roeder
Ludwig Maximilians Universitat Munchen, Klinik und Poliklinik fur Dermatologie und Allergologie, Frauenlobstrasse 9 11, DE 80337 Munich, Germany
Skin Pharmacol Physiol 18:3-11. 2005..Even among paediatric patients with atopic dermatitis, fluticasone propionate proved to be safe and effective. These pharmacological and clinical properties are reflected by the high therapeutic index of this glucocorticoid...
Anti-inflammatory activity of hamamelis distillate applied topically to the skin. Influence of vehicle and doseH C Korting
Department of Dermatology, Ludwig Maximilians Universitat, Munchen, Germany
Eur J Clin Pharmacol 44:315-8. 1993..The results have demonstrated an anti-inflammatory activity of hamamelis distillate in a PC-containing vehicle. A fourfold increase of drug concentration, however, did not produce an increase in activity...
The definition of Trichophyton rubrum syndromeG Kick
Department of Dermatology, Ludwig-Maximilians-University, Munich, Germany
Mycoses 44:167-71. 2001..This standardization is a prerequisite for further investigations of underlying mechanisms of this disease. The typical clinical pattern of TRS is illustrated by the presentation of two paradigmatic cases...
Efficacy and safety of a new single-dose terbinafine 1% formulation in patients with tinea pedis (athlete's foot): a randomized, double-blind, placebo-controlled studyJ P Ortonne
Dermatology Department, Hôpital L Archet 2, Nice, France, and Department of Dermatology, Ludwig Maximillians University, Munich, Germany
J Eur Acad Dermatol Venereol 20:1307-13. 2006..Terbinafine (presently used as a 1-week topical treatment of tinea pedis) is now available in a novel topical solution (film-forming solution--FFS), developed to allow single application...
Comparative therapeutic and toxic effects of different povidone iodine (PVP-I) formulations in a model of oral candidosis based on in vitro reconstituted epitheliumA Bonowitz
Department of Dermatology and Allergology, Ludwig-Maximilians-University Munich, Frauenlobstr. 9-11, D-80337 Munich, Germany
J Drug Target 9:75-83. 2001..In conclusion the liposomal PVP-I formulation appeared superior to the conventional ointment formulation because of both less toxicity and better therapeutical effects...
Effective treatment for dermatophytoses of the foot: effect on restoration of depressed cell-mediated immunityM H Schmid-Wendtner
Department of Dermatology and Allergology, Rheinische Friedrich Wilhelm University, Bonn, Germany
J Eur Acad Dermatol Venereol 21:1013-8. 2007..Just recently, effective antimycotic treatment, in particular with terbinafine, was shown to enhance and restore cell-mediated immunity, which potentially improves the therapeutic outcome even for this group of patients...
Current and future approaches to antimycotic treatment in the era of resistant fungi and immunocompromised hostsJ Bastert
, Frauenlobstr. 9-11, 80337, , Germany
Int J Antimicrob Agents 17:81-91. 2001..Fortunately, conventional antimycotics have been improved and entirely new ones are on the horizon as well as alternative approaches such as immunoreconstitution...
[Treatment of interdigital tinea pedis]H C Korting
, , Munich
Dtsch Med Wochenschr 128:1819-24. 2003..This may be explained by the fungicidal mode of action of the allylamines and the favourable pharmacokinetic characteristics of terbinafine, in contrast to the fungistatic mechanism of the azoles...
Cream or foam in pedal skin care: towards the ideal vehicle for urea used against dry skinC Borelli
Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität München, Frauenlobstrasse 9 11, Munich, Germany
Int J Cosmet Sci 33:37-43. 2011..At present it looks as if cream vehicles would still be vehicles of choice in general, when it comes to the formulation of skin care preparations for not only dry skin but also in the context of pedal skin care...
Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivoM Schaller
Department of Dermatology and Allergology, Ludwig Maximilians University Munich, Germany
J Med Microbiol 50:743-7. 2001..In particular it was localised at the tips of hyphal cells during invasion. These data suggest a different pathogenetic role for Sap1-3 and Sap4-6 during host-fungal interaction...
[Generalized Mycobacterium avium-intracellulare infection due to immunosuppressive therapy of paraneoplastic dermatomyositis]M Schaller
Dermatologische Klinik und Poliklinik, Ludwig Maximilians Universitat, Munchen
Hautarzt 48:118-21. 1997....
Evidence for the phagocytosis of intact oligolamellar liposomes by human keratinocytes in vitro and consecutive intracellular disintegrationH C Korting
Department of Dermatology, Ludwig Maximilians University, , Germany
J Microencapsul 10:223-8. 1993..If incorporated into lysosomes the structural lipids can be disintegrated and spread within the entire phagolysosome. Gold labeling adds further to the hypothesis of intact uptake of liposomes by the living cells of the human epidermis...
[Conventional and molecular diagnosis of cutaneous mycoses]C Borelli
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstrasse 9 11, 80337, Munchen
Hautarzt 59:980-5. 2008..Genotypic approaches to detection and identification of fungal pathogens have become very rapid and sensitive, making them additional options for routine diagnosis...
Toxicity and antimicrobial activity of a hydrocolloid dressing containing silver particles in an ex vivo model of cutaneous infectionM Schaller
Department of Dermatology and Allergology, University of Munich, Frauenlobstrasse 9 11, DE 80337 Munich, Germany
Skin Pharmacol Physiol 17:31-6. 2004..We present evidence that delivering silver to infected keratinocytes in a moist healing environment improves the benefit/risk ratio as compared to silver-free wound dressings...
Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungiC Borelli
Department of Dermatology and Allergology, Ludwig Maximilians University, Munich, Germany
Chemotherapy 54:245-59. 2008..In contrast to the increasing numbers of agents for the treatment of invasive fungal infections, discoveries of new antifungal agents with therapeutic value in dermatomycoses are reported only rarely...
Activity of different desoximetasone preparations compared to other topical corticosteroids in the vasoconstriction assayC Borelli
Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität, Munchen, Deutschland
Skin Pharmacol Physiol 21:181-7. 2008..The purpose of the study was to investigate the topical bioavailability of different topical corticosteroid formulations in healthy human beings focussing on desoximetasone (DM)...
Actinic keratosis: the key event in the evolution from photoaged skin to squamous cell carcinoma. Therapy based on pathogenetic and clinical aspectsT Oppel
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
Skin Pharmacol Physiol 17:67-76. 2004..The concept of the disease continuum from AK to squamous cell carcinoma will also be presented. A special focus will be on established and new therapeutic approaches to undo photoinduced skin damage...
The secreted aspartic proteinases as a new target in the therapy of candidiasisM Bein
Department of Dermatology, Ludwig Maximilians University, Munich, Germany
Curr Drug Targets 3:351-7. 2002..Therefore, drugs like the HIV proteinase inhibitors could play an essential role in the treatment of candidiasis in the future, especially if further adapted to this target...
Xerosis and callus formation as a key to the diabetic foot syndrome: dermatologic view of the problem and its managementTatjana Pavicic
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Ludwig Maximilians Universität, D 80337 München, Germany
J Dtsch Dermatol Ges 4:935-41. 2006..The most important therapeutic goals are optimal control of the diabetes mellitus, relieving pressure points and avoiding or reducing callus formation...
[Cellulite--the greatest skin problem in healthy people? An approach]Tatjana Pavicic
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Universitat Munchen, Germany
J Dtsch Dermatol Ges 4:861-70. 2006..The latter approach has been evidence-based with respect to caffeine liposomal cream and retinol cream...
Bilateral areolar and periareolar pityriasis versicolorMiklós Sárdy
Dept of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
J Dtsch Dermatol Ges 8:617-8. 2010..An adolescent boy presented with isolated, symmetrical, bilateral areolar and periareolar pityriasis versicolor. This extremely rare condition should be considered in the differential diagnosis of light brown patches on the areolae...
Sphingosine-1-phosphate signaling and the skinThomas Herzinger
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilian University, Munich, Germany
Am J Clin Dermatol 8:329-36. 2007..Topical use of S1P and other sphingosine compounds is also under investigation, particularly for the treatment of acne vulgaris...
Comparative study of 2% sertaconazole solution and cream formulations in patients with tinea corporis, tinea pedis interdigitalis, or a corresponding candidosisClaudia Borelli
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
Am J Clin Dermatol 8:371-8. 2007..Based on the results of numerous preclinical and clinical studies, sertaconazole can be considered a safe and effective drug for the treatment of fungal skin infections...
X-ray structures of Sap1 and Sap5: structural comparison of the secreted aspartic proteinases from Candida albicansClaudia Borelli
Department of Dermatology and Allergy, Ludwig Maximilian University, 80337 Munich, Germany
Proteins 72:1308-19. 2008..Determination of the isoenzymes' structures can contribute to the development of new Sap-specific inhibitors for the treatment of superficial infections with a structure-based drug design program...
[Evidence-based cosmetics: concepts and applications in photoaging of the skin and xerosis]Tatjana Pavicic
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Universitat Munchen, Germany
Wien Klin Wochenschr 121:431-9. 2009..Moreover, generally accepted guidelines for the examination of efficacy and tolerability of dermocosmetics have to be developed...
Monophasic, cohesive-polydensified-matrix crosslinking-technology-based hyaluronic acid filler for the treatment of facial lipoatrophy in HIV-infected patientsTatjana Pavicic
Department of Dermatology, Ludwig Maximillians University, Munich, Germany
J Drugs Dermatol 9:690-5. 2010..A limited quantity of data has been published on various filling substances for the management of FLA. Here, the authors present two patients with HIV-associated FLA successfully treated with a novel HA filler over a period of 24 months...
Safety and efficacy of sertaconazole nitrate cream 2% in the treatment of tinea pedis interdigitalis: a subgroup analysisClaudia Borelli
Department of Dermatology and Allergology, Ludwig Maximilians Universitat Munchen, Munich Germany
Cutis 85:107-11. 2010..The rate of reported AEs was low (8.7% [8/92]), and none were considered serious. These findings indicate that sertaconazole nitrate cream 2% is highly safe and effective in the treatment of tinea pedis interdigitalis...
Hydroxyethyl starch-induced itch: relevance of light microscopic analysis of semi-thin sections and electron microscopyStefanie Kamann
Clinic and Polyclinic for Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
J Dtsch Dermatol Ges 5:204-8. 2007..Our aim was to compare electron microscopic search for HES deposits with other techniques...
Lactobacilli - bacteria-host interactions with special regard to the urogenital tractKathrin Merk
Klinikum der Universitat Munchen, Klinik und Poliklinik für Dermatologie und Allergologie Innenstadt, Frauenlobstr 9 11, D 8033 7 München, Germany
Int J Med Microbiol 295:9-18. 2005..This review is aimed to present and discuss results concerning interactions of lactobacilli and immune system or epithelial cells with focus to urogenital mucosa...
The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin AClaudia Borelli
Department of Dermatology and Allergy, Ludwig Maximilian University of Munich, Frauenlobstr 9 11, 80337 Munich, Germany
Proteins 68:738-48. 2007..Inhibitor binding causes active site closure by the movement of a flap segment. Comparison of the structures of Sap3 and Sap2 identifies elements responsible for the specificity of each isoenzyme...
Improved differentiation of benign and malignant lymphadenopathy in patients with cutaneous melanoma by contrast-enhanced color Doppler sonographyMonika Hildegard Schmid-Wendtner
Department of Dermatology and Allergology, Ludwig Maximilians University, Frauenlobstr 9 11, D 80337 Munich, Germany
Arch Dermatol 138:491-7. 2002....
Different skin thinning potential of equipotent medium-strength glucocorticoidsHans Christian Korting
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Munich, Germany 80337
Skin Pharmacol Appl Skin Physiol 15:85-91. 2002..Prednicarbate is a topical glucocorticoid with an improved benefit/risk ratio, as it causes less skin atrophy than the equipotent betamethasone 17-valerate...
[Use of Lactobacillus as a probiotic factor to treat urogenital and intestinal infections as well as to prevent and treat allergic diseases]Kathrin Merk
Klinikum der Universitat Munchen, Klinik und Poliklinik für Dermatologie und Allergologie Innenstadt
J Dtsch Dermatol Ges 2:752-7. 2004..The preventive and therapeutic effect of lactobacilli applies to diarrhoea and urogenital infections in particular. Lactobacilli also seem to have a protective influence on the development and treatment of atopic disease...
[Grover's disease following hemodialysis in a patient with renal failure]Martina Moderer
Klinik und Poliklinik für Dermatologie und Allergologie der Universität München
J Dtsch Dermatol Ges 2:203-5. 2004..There are only few case reports in the literature describing Grover's disease occurring during hemodialysis treatment. All such previous patients have been men; ours is the first woman...
Chitin modulates innate immune responses of keratinocytesBarbara Koller
Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany
PLoS ONE 6:e16594. 2011..The skin represents the outer barrier of the human host defense and is in frequent contact with chitin-bearing organisms, such as house-dust mites or flies. The effects of chitin on keratinocytes, however, are poorly understood...
Dermatomycological guidelines: 10 years of experience in GermanyC Seebacher
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Universitat Munchen, Munchen, Germany
Mycoses 50:422-5. 2007..All guidelines are subject to adaptation in a period of 3-5 years at the latest or if needed even earlier...
Hyaluronic acid in the treatment and prevention of skin diseases: molecular biological, pharmaceutical and clinical aspectsG Weindl
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
Skin Pharmacol Physiol 17:207-13. 2004..Therefore, ongoing research offers new horizons for the therapeutic use of this glycosaminoglycan which has been regarded as an inert structural component until recently...
[Mycological laboratory]B Beifuss
Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität, Frauenlobstrasse 9 11, 80337, Munchen
Hautarzt 57:487-8, 490-2. 2006....
Tazarotene: therapeutic strategies in the treatment of psoriasis, acne and photoagingA Roeder
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Frauenlobstrasse 9 11, DE 80337 Munich, Germany
Skin Pharmacol Physiol 17:111-8. 2004..Novel therapeutic regimens such as short-contact therapy have been developed for both acne and psoriasis in order to diminish the major adverse events like pruritus, burning, local skin irritation and erythema...
Current state of three-dimensional characterisation of antifungal targets and its use for molecular modelling in drug designE Ruge
Department of Dermatology, University of Munich, Frauenlobstr 9 11, 80337 Munich, Germany
Int J Antimicrob Agents 26:427-41. 2005..Three-dimensional characterisation has become a well established tool for modern antifungal drug research and should play an important role in investigations for new antifungal agents...
High concentrations of antibiotic obtained for a short time excel more long-standing lower levels in the therapy of gonorrhoea. Implications of an in vitro modelH C Korting
Dermatologische Klinik und Poliklinik, Ludwig Maximilians Universitat, Munchen, BRD
Chemotherapy 34:142-8. 1988....
[Non-pharmacologic management of rosacea]C Borelli
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstr 9 11, 80337 München
Hautarzt 62:828-33. 2011..Laser or intense pulsed light treatment can improve telangiectasia or erythema. Operative treatment of rhinophyma is effective and well-established...
Sunscreens - which and what for?T Maier
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
Skin Pharmacol Physiol 18:253-62. 2005..This article reviews the efficacy of sunscreens in the prevention of epithelial and nonepithelial skin cancer, the effect on immunosuppression and the value of the SPF as well as new developments on the sunscreen market...
Deep subcutaneous application of poly-L-lactic acid as a filler for facial lipoatrophy in HIV-infected patientsC Borelli
Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany
Skin Pharmacol Physiol 18:273-8. 2005..As the depth of injection was considered relevant in this context, the application modalities of the preparation were changed. The preparation was to be injected more deeply into subcutaneous tissue, after increased dilution...
[Physical treatment methods for acne. Light, laser, photodynamic therapy and peeling]C Borelli
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstr 9 11, 80337 München
Hautarzt 61:132-8. 2010..UV treatment of acne is obsolete. Newer studies on the use of a variety of laser systems and flash lamps have demonstrated in part rewarding results...
Ciclopiroxolamine cream for treating seborrheic dermatitis: a double-blind parallel group comparisonA Unholzer
Clinic for Dermatology and Allergology, Ludwig-Maximilians University, Munich, Germany
Infection 30:373-6. 2002..001). CONCLUSION: This study confirms that topical treatment with ciclopiroxolamine is effective and well tolerated in patients with seborrheic dermatitis...
[Juvenile verrucae planae: treatment with imiquimod 5% cream]M Mühlstädt
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Universitat Munchen, Frauenlobstrasse 9 11, 80337, Munchen, Germany
Hautarzt 58:54-5. 2007..After four weeks of treatment the lesions had vanished completely. We suggest imiquimod 5% cream as a treatment option for juvenile plane warts even in children and in the face...
Perniosis-like tinea corporis caused by Trichophyton verrucosum in cold-exposed individualsM Placzek
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Frauenlobstrasse, D 80337, Munchen, Germany
Mycoses 49:476-9. 2006..Dermatophytosis caused by T. verrucosum can, under certain circumstances, such as frequent exposure to cold or a long-term corticosteroid therapy, mimic the characteristic clinical picture of perniosis, as we demonstrate here...
Bioavailability, antipsoriatic efficacy and tolerability of a new light cream with mometasone furoate 0.1%H C Korting
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
Skin Pharmacol Physiol 25:133-41. 2012..Mometasone cream, in addition to its high potency and good tolerability, provides the properties of a light cream, which might make this new medication particularly suitable for application on acutely inflamed and sensitive skin...
The sign of Leser-Trélat: a paraneoplastic cutaneous syndrome that facilitates early diagnosis of occult cancerV Vielhauer
Medizinische Poliklinik, Ludwig Maximilians Universitat Munchen, Pettenkoferstr 8a, D 80336 MUnchen, Germany
Eur J Med Res 5:512-6. 2000..A review on this and other cutaneous paraneoplastic syndromes is given. Since they may be the only presenting sign of an occult cancer, patients with these syndromes should undergo a diagnostic screening program for malignant disease...
Phospholipases of Candida albicansM Niewerth
, , Germany
Mycoses 44:361-7. 2001..Yet it can be supposed today that phospholipases are one important factor in this complex interaction. Therefore the known phospholipases of C. albicans are described in detail under clinical aspects...
Surgical treatment of tinea capitis in childhoodE Thoma-Greber
, , Frauenlobstrasse 8-11, , Germany
Mycoses 46:351-4. 2003....
Influence of various concentrations of cefotiam and ceftizoxime on the phagocytosis of gonococci by polymorphonuclear granulocytesH C Korting
Department of Dermatology, Ludwig Maximilians University, Munich, Fed Rep of Germany
Arzneimittelforschung 39:428-31. 1989..As light microscopic investigation allows the analysis of large numbers of cells but no final judgement on actual bacterial engulfment definite phagocytosis is demonstrated by electron microscopy...
Innate immune receptors on neutrophils and their role in chronic lung diseaseB Koller
Children s Hospital Research Center, Department of Dermatology, LMU University of Munich, Munich, Germany
Eur J Clin Invest 39:535-47. 2009..Here we summarize and discuss recent advances in the expression, regulation and functional role of TLRs on neutrophils in chronic lung diseases...
Erythema induratum of Bazin. Evidence of T-lymphocyte hyperresponsiveness to purified protein derivative of tuberculin: report of two cases and treatmentM W Ollert
Department of Dermatology, Ludwig Maximilians Universitat, Munich, Germany
Arch Dermatol 129:469-73. 1993....
[Therapeutic or prophylactic antifungal vaccination: problems and solutions]S Boneberger
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum Innenstadt, Ludwig Maximilians Universitat Munchen, Frauenlobstrasse 9 11, 80337, Munchen, Deutschland
Hautarzt 59:828-32. 2008..However, classic vaccines might be of limited efficacy in fungal infections since fungi elicit primarily cellular immune responses...
Penciclovir cream--improved topical treatment for herpes simplex infectionsM H Schmid-Wendtner
Department of Dermatology and Allergology, Rheinische Friedrich Wilhelm University, Bonn, Germany
Skin Pharmacol Physiol 17:214-8. 2004....
Human epithelial cells establish direct antifungal defense through TLR4-mediated signalingGunther Weindl
Department of Dermatology, Eberhard Karls University of Tubingen, Tubingen, Germany
J Clin Invest 117:3664-72. 2007....
Toll-like receptors and innate antifungal responsesAlexander Roeder
Department of Dermatology, Ludwig-Maximilians-University, 80337 Munich, Germany
Trends Microbiol 12:44-9. 2004....
Peroxisome proliferator-activated receptors and their ligands: entry into the post-glucocorticoid era of skin treatment?Gunther Weindl
Department of Dermatology, University of Tubingen, Tubingen, Germany
Drugs 65:1919-34. 2005..Nonetheless, PPARs seem to have significant potential as therapeutic targets in skin inflammatory disorders...
Human defensinsJosef Johann Schneider
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstrasse 9 11, 80337 Munich, Germany
J Mol Med (Berl) 83:587-95. 2005..Its bactericidal activity against P. aeruginosa is stronger than that of the other known beta-defensins. Here we present an overview of human antimicrobial peptides with some emphasis on their antifungal properties...
[Topical skin therapy with glucocorticoids--therapeutic index]Thomas Luger
J Dtsch Dermatol Ges 2:629-34. 2004
Tinea capitisClaus Seebacher
J Dtsch Dermatol Ges 4:1085-91. 2006
OnychomycosisClaus Seebacher
Dresden, Germany
J Dtsch Dermatol Ges 5:61-6. 2007
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetySiddharth Mukherjee
Department of Pharmacology, Bombay College of Pharmacy, Kalina, Santacruz (E, Mumbai, India
Clin Interv Aging 1:327-48. 2006..However, more elaborate clinical studies are required to confirm their advantage in the delivery of topical retinoids...
Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicansHans-Christian Sigle
, , , , D-14195 Berlin, Germany
J Antimicrob Chemother 55:663-73. 2005..CONCLUSIONS: These data indicate that metabolic activity, oxygen accessibility and iron levels are critical parameters in the mode of action of ciclopirox olamine...
Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factorsMarkus Niewerth
Robert Koch-Institut, 13353 Berlin, Germany
Antimicrob Agents Chemother 47:1805-17. 2003..Furthermore, neither the expression of certain multiple-drug resistance genes nor other resistance mechanisms caused C. albicans resistance to this drug even after long-term exposure...
Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: particle characterisation and skin uptakeJana Stecová
Institut fur Pharmazie, Freie Universitat Berlin, Konigin Luise Strasse 2 4, D 14195, Berlin, Germany
Pharm Res 24:991-1000. 2007..To improve skin penetration of the poorly absorbed drug, we intended to identify the active moiety and to load it to particulate carrier systems...
Reconstructed human epidermis for skin absorption testing: results of the German prevalidation studyMonika Schäfer-Korting
Freie Universitat Berlin, Institut fur Pharmazie, Konigin Luise Strasse 2 4, 14195 Berlin, Germany
Altern Lab Anim 34:283-94. 2006..Long and variable lag times, which are a matter of concern when using human and pig skin, did not occur with RHE. Due to the successful transfer of the protocol, it is now in the validation process...
The use of reconstructed human epidermis for skin absorption testing: Results of the validation studyMonika Schäfer-Korting
Freie Universitat Berlin, Institut fur Pharmazie, Berlin, Germany
Altern Lab Anim 36:161-87. 2008..Thus, the RHE models, EPISKIN, EpiDerm and SkinEthic, are appropriate alternatives to human and pig skin, for the in vitro assessment of the permeation and penetration of substances when applied as aqueous solutions...
[Tinea capitis]Claus Seebacher
J Dtsch Dermatol Ges 2:462-8. 2004
Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in miceMarianne Kretschmar
, , Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany
Microb Pathog 32:61-70. 2002..We conclude that although Saps were produced, individual Saps were not indispensable factors for virulence during gastrointestinal infection of mice...
[Oral candidiasis]Dieter Reinel
Bundeswehrkrankenhaus Hamburg, Abt. f. Dermatologie, Venerologie und Allergologie
J Dtsch Dermatol Ges 2:874-6. 2004
[Dermatological guideline efforts for 2007 in perspective]Hans Christian Korting
J Dtsch Dermatol Ges 5:1-3. 2007
