Research Topics
| G KorinthSummaryAffiliation: University of Erlangen-Nuremberg Country: Germany Publications
| Collaborators |
Detail Information
Publications
Discrepancies between different rat models for the assessment of percutaneous penetration of hazardous substancesGintautas Korinth
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine, University Erlangen Nuremberg, Schillerstrasse 25 29, 91054 Erlangen, Germany
Arch Toxicol 81:833-40. 2007..Due to these differences the reliability of a conversion factor for the transfer of percutaneous absorption data from rat to human skin, as proposed in the literature, is questionable...
Percutaneous absorption and metabolism of 2-butoxyethanol in human volunteers: a microdialysis studyGintautas Korinth
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine, University Erlangen Nuremberg, Schillerstrasse 25 29, D 91054 Erlangen, Germany
Toxicol Lett 170:97-103. 2007..03% to 1.9% of the BE in the same dialysate. Our study demonstrates applicability of microdialysis technique for assessment of percutaneous absorption kinetics and dermal metabolism without interference from the systemic compartment...
Percutaneous absorption of aromatic amines in rubber industry workers: impact of impaired skin and skin barrier creamsG Korinth
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Erlangen, Germany
Occup Environ Med 64:366-72. 2007..However, little is known about the percutaneous absorption of chemicals via impaired skin and about the efficacy of skin protection measures to reduce internal exposure...
Investigations on permeation of mitomycin C through double layers of natural rubber glovesGintautas Korinth
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine of the University Erlangen Nuremberg, Schillerstrasse 25 29, D 91054 Erlangen, Germany
Ann Occup Hyg 51:593-600. 2007..However, occupational exposure to antineoplastic drugs should be minimized, since there is insufficient knowledge regarding harmful effects from a long-term exposure to low doses...
Visible and subclinical skin changes in male and female dispatch department workers of newspaper printing plantsGintautas Korinth
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Erlangen, Germany
Skin Res Technol 11:132-9. 2005..In contrast, physical irritation of the skin as another potential cause of occupational hand dermatitis has been investigated less...
Is the permeability coefficient Kp a reliable tool in percutaneous absorption studies?Gintautas Korinth
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine, University Erlangen Nuremberg, Schillerstrasse 25 29, 91054, Erlangen, Germany
Arch Toxicol 79:155-9. 2005..The results of our experiments showed that the permeability coefficient Kp was not able to adjust the flux of BE to the concentration. This is in agreement with the evaluation of Kp from BE data described in the literature...
Skin strain and its influence on systemic exposure to a glycol ether in offset printing workersG Korinth
Institute and Out Patient Clinic for Occupational, Social and Environmental Medicine, University Erlangen Nuremberg, Erlangen, Germany
Contact Dermatitis 49:248-54. 2003..We were able to show that by using a multiple spectrum of methods an enhancement of percutaneous absorption of BEE could be demonstrated in workers with skin lesions...
In vitro evaluation of the efficacy of skin barrier creams and protective gloves on percutaneous absorption of industrial solventsG Korinth
Institute and Out Patient Clinic for Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Schillerstrasse 25 29, 91054 Erlangen, Germany
Int Arch Occup Environ Health 76:382-6. 2003..The aim of the experiments was to evaluate the efficacy of skin barrier creams (SBCs) and protective gloves and its potential for reduction of percutaneous absorption of industrial solvents...
Enhancement of percutaneous penetration of aniline and o-toluidine in vitro using skin barrier creamsGintautas Korinth
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine, University Erlangen Nuremberg, Schillerstrasse 25 29, D 91054 Erlangen, Germany
Toxicol In Vitro 22:812-8. 2008..The efficacy of skin creams to protect the percutaneous penetration of aromatic amines is not confirmed by our own experiments...
Percutaneous absorption of aromatic amines - a contribution for human health risk assessmentT Wellner
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine, University Erlangen Nuremberg, Schillerstrasse 25 29, D 91054 Erlangen, Germany
Food Chem Toxicol 46:1960-8. 2008..The in vitro data support our recent findings in rubber industry workers that the percutaneous absorption may significantly contribute to overall exposure of AA...
Investigations on safety of hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) with Mitomycin CK Schmid
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine of the University Erlangen Nuremberg, Schillerstrasse 25 29, D 91054 Erlangen, Germany
Eur J Surg Oncol 32:1222-5. 2006..We re-evaluated possible safety hazards of HIPEC by applying different monitoring strategies...
Cardiovascular function of workers exposed to carbon disulphideG Korinth
Department and Out-Patient Clinic for Occupational, Social and Environmental Medicine, University Erlangen-Nuremberg, Schillerstrasse 25/29, 91054 Erlangen, Germany
Int Arch Occup Environ Health 76:81-5. 2003..CONCLUSIONS: In this study, differences in the heart chamber diameters between exposed persons and controls could not be confirmed. Differences in physical fitness and constitution can explain differences in heart chamber diameters...
Commentary on "Penetration of benzene, toluene and xylenes contained in gasolines through human abdominal skin in vitro"Eberhard Nies
BG Institute for Occupational Safety and Health BGIA, Sub division Toxicology of Industrial Chemicals, Alte Heerstrasse 111, 53757 Sankt Augustin, Germany
Toxicol In Vitro 22:275-7. 2008..This knowledge is important for the judgment of leukaemia suspected to be an occupational disease...
Butoxyethoxyacetic acid, a biomarker of exposure to water-based cleaning agentsThomas Göen
Institute and Outpatient Clinic for Occupational Medicine, University Hospital, Pauwelsstrasse 30, D 52074 Aachen, Germany
Toxicol Lett 134:295-300. 2002..5 mg/l. A protective effect on DEGBE uptake was observed with the use of protective gloves. This observation implies that dermal penetration of DEGBE may be important in exposure monitoring...
