Stefan Jenisch

Summary

Affiliation: University of Kiel
Country: Germany

Publications

  1. ncbi Linkage disequilibrium analysis of familial psoriasis: identification of multiple disease-associated MHC haplotypes
    S Jenisch
    Department of Immunology, University of Kiel, Germany
    Tissue Antigens 53:135-46. 1999
  2. ncbi CARD15 mutations in patients with plaque-type psoriasis and psoriatic arthritis: lack of association
    Stefan Jenisch
    Department of Immunology, University of Kiel, Michaelisstr 5, 24105, Kiel, Germany
    Arch Dermatol Res 297:409-11. 2006
  3. ncbi Corneodesmosin gene polymorphism demonstrates strong linkage disequilibrium with HLA and association with psoriasis vulgaris
    S Jenisch
    Department of Immunology, University of Kiel, Germany
    Tissue Antigens 54:439-49. 1999
  4. ncbi Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis
    Dorothea M Sommer
    Department of Dermatology, University of Kiel, Schittenhelmstrasse 7, 24105 Kiel, Germany
    Arch Dermatol Res 298:321-8. 2006
  5. ncbi Bypassing hybridoma technology: HLA-C reactive human single-chain antibody fragments (scFv) derived from a synthetic phage display library (HuCAL) and their potential to discriminate HLA class I specificities
    M Marget
    Institut fur Immunologie, Klinikum der Universität Kiel, Germany
    Tissue Antigens 56:1-9. 2000
  6. ncbi Semiquantitative reverse transcription polymerase chain reaction analysis for detection of bcr/abl rearrangement using RNA extracts from bone marrow aspirates compared with glass slide smears after 0, 2 and 4 d of storage
    R Schoch
    Department of Internal Medicine II, Christian Albrechts University of Kiel, Germany
    Br J Haematol 115:583-7. 2001
  7. ncbi HLA-DRB1 and anti-cyclic citrullinated peptide antibody production in rheumatoid arthritis
    Ilka Senkpiehl
    Department of Immunology, UKS-H Campus Kiel, Germany
    Int Arch Allergy Immunol 137:315-8. 2005
  8. ncbi Integration of amplified BCR/ABL fusion genes into the short arm of chromosome 17 as a novel mechanism of disease progression in chronic myeloid leukemia
    S Metzke-Heidemann
    Department of Human Genetics, Christian-Albrechts-University, Kiel, Germany
    Genes Chromosomes Cancer 31:10-4. 2001
  9. ncbi Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene
    Rajan P Nair
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109 0932, USA
    Am J Hum Genet 78:827-51. 2006
  10. ncbi Filaggrin R501X and 2282del4 mutations are not associated with chronic plaque-type psoriasis in a German cohort
    Michael Weichenthal
    J Invest Dermatol 127:1535-7. 2007

Collaborators

Detail Information

Publications15

  1. ncbi Linkage disequilibrium analysis of familial psoriasis: identification of multiple disease-associated MHC haplotypes
    S Jenisch
    Department of Immunology, University of Kiel, Germany
    Tissue Antigens 53:135-46. 1999
    ..These results identify a major PsV susceptibility locus in the immediate vicinity of, but distinct from HLA-B or HLA-C, and suggest that multiple disease alleles have arisen during human evolution...
  2. ncbi CARD15 mutations in patients with plaque-type psoriasis and psoriatic arthritis: lack of association
    Stefan Jenisch
    Department of Immunology, University of Kiel, Michaelisstr 5, 24105, Kiel, Germany
    Arch Dermatol Res 297:409-11. 2006
    ..All other variants including leu1007fsinsC and R702W did not show any association with psoriasis or PsA. In conclusion, a disease-causing role for CARD15 mutations could not be confirmed in German or American subjects with PsA...
  3. ncbi Corneodesmosin gene polymorphism demonstrates strong linkage disequilibrium with HLA and association with psoriasis vulgaris
    S Jenisch
    Department of Immunology, University of Kiel, Germany
    Tissue Antigens 54:439-49. 1999
    ..Due to its biologic function, cellular location and disease association, the CD gene appears to be an excellent candidate gene for PSORS1, the HLA-linked determinant of psoriasis vulgaris...
  4. ncbi Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis
    Dorothea M Sommer
    Department of Dermatology, University of Kiel, Schittenhelmstrasse 7, 24105 Kiel, Germany
    Arch Dermatol Res 298:321-8. 2006
    ..The risk of late term cardiovascular complications might support the use of systemic treatment in psoriasis...
  5. ncbi Bypassing hybridoma technology: HLA-C reactive human single-chain antibody fragments (scFv) derived from a synthetic phage display library (HuCAL) and their potential to discriminate HLA class I specificities
    M Marget
    Institut fur Immunologie, Klinikum der Universität Kiel, Germany
    Tissue Antigens 56:1-9. 2000
    ..This approach might be a valuable tool to develop a broad range of novel monospecific antibodies against HLA-class I specificities...
  6. ncbi Semiquantitative reverse transcription polymerase chain reaction analysis for detection of bcr/abl rearrangement using RNA extracts from bone marrow aspirates compared with glass slide smears after 0, 2 and 4 d of storage
    R Schoch
    Department of Internal Medicine II, Christian Albrechts University of Kiel, Germany
    Br J Haematol 115:583-7. 2001
    ..Glass slide smears were equivalent to bone marrow aspirates in 8 out of 11 cases as a source for RT-PCR analysis when nested PCR was performed...
  7. ncbi HLA-DRB1 and anti-cyclic citrullinated peptide antibody production in rheumatoid arthritis
    Ilka Senkpiehl
    Department of Immunology, UKS-H Campus Kiel, Germany
    Int Arch Allergy Immunol 137:315-8. 2005
    ..HLA-DRB1*0401 is not a prerequisite for anti-CCP production, but if HLA-DRB1*0401 was present, 90% of our RA patients were anti-CCP positive...
  8. ncbi Integration of amplified BCR/ABL fusion genes into the short arm of chromosome 17 as a novel mechanism of disease progression in chronic myeloid leukemia
    S Metzke-Heidemann
    Department of Human Genetics, Christian-Albrechts-University, Kiel, Germany
    Genes Chromosomes Cancer 31:10-4. 2001
    ..Furthermore, the insertion of amplified BCR/ABL fusion genes into structurally abnormal chromosomes provides a novel mechanism of disease progression in BCR/ABL-positive CML...
  9. ncbi Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene
    Rajan P Nair
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109 0932, USA
    Am J Hum Genet 78:827-51. 2006
    ..These results strongly suggest that HLA-Cw6 is the PSORS1 risk allele that confers susceptibility to early-onset psoriasis...
  10. ncbi Filaggrin R501X and 2282del4 mutations are not associated with chronic plaque-type psoriasis in a German cohort
    Michael Weichenthal
    J Invest Dermatol 127:1535-7. 2007
  11. ncbi Polymorphisms of the IL12B and IL23R genes are associated with psoriasis
    Rajan P Nair
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0932, USA
    J Invest Dermatol 128:1653-61. 2008
    ..Our results confirm associations between IL12B and IL23R and psoriasis in Caucasians, and provide a genetic basis for the clinical association between psoriasis and Crohn's disease...
  12. ncbi Protein tyrosine phosphatase gene PTPN22 polymorphism in psoriasis: lack of evidence for association
    Ioana Nistor
    J Invest Dermatol 125:395-6. 2005
  13. ncbi Analysis of phenotypic variation in psoriasis as a function of age at onset and family history
    Philip Stuart
    Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Arch Dermatol Res 294:207-13. 2002
    ..The lack of clinical differences between "familial" and "sporadic" psoriasis may reflect a similar genetic basis for both conditions, at least when onset is early...
  14. ncbi Combined segregation and linkage analysis of HLA markers in familial psoriasis
    Sun-Wei Guo
    Department of Pediatrics, Medical College of Wisconsin, Wisconsin, USA
    Eur J Hum Genet 10:327-33. 2002
    ..The results are very consistent with our current knowledge of PSORS1, and suggest that MBSA can provide useful information on genotype-phenotype relationships such as penetrance and allelic heterogeneity...
  15. ncbi Nonelectrophoretic method for high-throughput HLA-DRB1 group genotyping
    Jochen Hampe
    Christian-Albrechts-University Kiel, Germany
    Biotechniques 36:148-51. 2004