Sven Jarius

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Neuroinflammation 7:21. 2010
  2. ncbi An early case of neuromyelitis optica: on a forgotten report by Jacob Lockhart Clarke, FRS
    S Jarius
    Department of Neurology, University of Heidelberg, Germany
    Mult Scler 17:1384-6. 2011
  3. ncbi 'Noteomielite' accompanied by acute amaurosis (1844). An early case of neuromyelitis optica
    S Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Germany
    J Neurol Sci 313:182-4. 2012
  4. ncbi Immunoglobulin M antibodies to aquaporin-4 in neuromyelitis optica and related disorders
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Clin Chem Lab Med 48:659-63. 2010
  5. ncbi Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Neuroinflammation 7:52. 2010
  6. ncbi Frequency and syndrome specificity of antibodies to aquaporin-4 in neurological patients with rheumatic disorders
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Mult Scler 17:1067-73. 2011
  7. ncbi B cells undergo unique compartmentalized redistribution in multiple sclerosis
    Jürgen Haas
    Division of Molecular Neuroimmunology, Department of Neurology, University Hospital Heidelberg, Germany
    J Autoimmun 37:289-99. 2011
  8. ncbi AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Nat Rev Neurol 6:383-92. 2010
  9. ncbi Long term survival in anti-Hu associated adult neuroblastoma
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Neurol Sci 284:205-8. 2009
  10. ncbi Aquaporin-4 antibody positive longitudinally extensive transverse myelitis following varicella zoster infection
    Kristin Heerlein
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Germany
    J Neurol Sci 276:184-6. 2009

Collaborators

Detail Information

Publications12

  1. ncbi A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Neuroinflammation 7:21. 2010
    ..Our findings suggest a role of autoimmunity against ARHGAP26 in the pathogenesis of subacute inflammatory cerebellar ataxia, and extend the panel of diagnostic markers for this devastating disease...
  2. ncbi An early case of neuromyelitis optica: on a forgotten report by Jacob Lockhart Clarke, FRS
    S Jarius
    Department of Neurology, University of Heidelberg, Germany
    Mult Scler 17:1384-6. 2011
    ....
  3. ncbi 'Noteomielite' accompanied by acute amaurosis (1844). An early case of neuromyelitis optica
    S Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Germany
    J Neurol Sci 313:182-4. 2012
    ..Pescetto's report represents the earliest account of a case of neuromyelitis optica in the Western literature known so far...
  4. ncbi Immunoglobulin M antibodies to aquaporin-4 in neuromyelitis optica and related disorders
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Clin Chem Lab Med 48:659-63. 2010
    ..Testing for AQP4-IgM may be of importance since 20%-30% of patients with NMO are negative for AQP4-IgG. Moreover, IgM antibodies are more potent activators of complement compared with IgG, and are detectable at NMO lesional sites...
  5. ncbi Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Neuroinflammation 7:52. 2010
    ..Recent evidence strongly suggests that AQP4-Ab are directly involved in the immunopathogenesis of NMO...
  6. ncbi Frequency and syndrome specificity of antibodies to aquaporin-4 in neurological patients with rheumatic disorders
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Mult Scler 17:1067-73. 2011
    ..However, AQP4-Ab has been found also in patients with co-existing rheumatic diseases such as systemic lupus erythematosus (SLE) or Sjögren's syndrome (SS), conditions which are characterized by broad, polyspecific B cell activation...
  7. ncbi B cells undergo unique compartmentalized redistribution in multiple sclerosis
    Jürgen Haas
    Division of Molecular Neuroimmunology, Department of Neurology, University Hospital Heidelberg, Germany
    J Autoimmun 37:289-99. 2011
    ....
  8. ncbi AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Nat Rev Neurol 6:383-92. 2010
    ..In this Review, we summarize the latest evidence in support of a direct involvement of AQP4-Ab in the immunopathogenesis of NMO, and critically appraise the diagnostic tests currently available for the detection of this serum reactivity...
  9. ncbi Long term survival in anti-Hu associated adult neuroblastoma
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Neurol Sci 284:205-8. 2009
    ..Serological testing demonstrated a marked decline in anti-Hu antibody titres under therapy, and subsequent disappearance of the antibody 31 months after second tumour resection...
  10. ncbi Aquaporin-4 antibody positive longitudinally extensive transverse myelitis following varicella zoster infection
    Kristin Heerlein
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Germany
    J Neurol Sci 276:184-6. 2009
    ..Our observations provide further evidence for a pathogenic role of AQP4-Ab in LETM and suggest that AQP4-Ab associated auto-immunity should be considered also in apparently infectious/parainfectious settings...
  11. ncbi Soluble CSF interleukin 2 receptor as indicator of neurosarcoidosis
    Hela Felicitas Petereit
    Department of Neurology, Holy Ghost Hospital, Graseggerstr 105, Cologne, Germany
    J Neurol 257:1855-63. 2010
    ..In conclusion, these findings suggest that sIL2-R measurement in the CSF may be a valuable tool in the diagnosis and follow-up of patients with suspected and proven neurosarcoidosis...
  12. ncbi The intrathecal, polyspecific antiviral immune response: Specific for MS or a general marker of CNS autoimmunity?
    Sven Jarius
    Division of Molecular Neuroimmunology, Department of Neurology, Ruprecht Karl University, Heidelberg, Germany
    J Neurol Sci 280:98-100. 2009
    ..Besides MS and CNS vasculitis, paraneoplastic neurological disorders (PND) represent the best recognized models of CNS autoimmunity...