Research Topics
Genomes and Genes | Susanne HeroldSummaryAffiliation: University of Giessen Country: Germany Publications
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Publications
Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligandSusanne Herold
University of Giessen Lung Center, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine and Infectious Diseases, Justus Liebig University, Giessen, Germany
J Exp Med 205:3065-77. 2008..Epithelial cell apoptosis induced by TRAIL-expressing macrophages is identified as a major underlying mechanism...
Exudate macrophages attenuate lung injury by the release of IL-1 receptor antagonist in gram-negative pneumoniaSusanne Herold
Department of Internal Medicine II, University of Giessen Lung Center, Giessen, Germany
Am J Respir Crit Care Med 183:1380-90. 2011..Exudate macrophages are key players in host defense toward invading pathogens. Their antiinflammatory and epithelial-protective potential in gram-negative pneumonia, however, remains elusive...
Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repairLidija Cakarova
University of Giessen Lung Center, Department of Internal Medicine II, Klinikstr 36, D 35392 Giessen, Germany
Am J Respir Crit Care Med 180:521-32. 2009..Resident alveolar macrophages have been attributed a crucial role in host defense toward pulmonary infection. Their contribution to alveolar repair processes, however, remains elusive...
Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharideWerner von Wulffen
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Giessen Lung Center, Giessen, Germany
Am J Respir Crit Care Med 176:892-901. 2007..However, the contribution of DCs to acute lung inflammation induced by inhaled bacterial toxins is largely unknown...
Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repairLeigh M Marsh
Department of Internal Medicine, Giessen and Marburg University, University Giessen Lung Centre, Giessen, Germany
Am J Physiol Lung Cell Mol Physiol 296:L442-52. 2009..These data suggest a previously unidentified role of MIF-CD74 interaction by inducing proliferation of AEC-II, which may contribute to alveolar repair...
Alveolar epithelial cells direct monocyte transepithelial migration upon influenza virus infection: impact of chemokines and adhesion moleculesSusanne Herold
University of Giessen Lung Center, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine and Infectious Diseases, Justus Liebig University, Giessen, Germany
J Immunol 177:1817-24. 2006....
Spatiotemporal expression of flk-1 in pulmonary epithelial cells during lung developmentKatrin Ahlbrecht
University of Giessen Lung Center, Department of Internal Medicine, University Hospital Giessen, Giessen, Germany
Am J Respir Cell Mol Biol 39:163-70. 2008..Investigations on transgenic mouse strains, containing either a complete or incomplete flk-1 promoter driving expression of the lacZ reporter gene, suggested differential flk-1 regulation in endothelial and epithelial cells...
The NS segment of an H5N1 highly pathogenic avian influenza virus (HPAIV) is sufficient to alter replication efficiency, cell tropism, and host range of an H7N1 HPAIVWenjun Ma
Institute of Medical Virology, Justus Liebig University, D 35392 Giessen, Germany
J Virol 84:2122-33. 2010....
TIAR and TIA-1 mRNA-binding proteins co-aggregate under conditions of rapid oxygen decline and extreme hypoxia and suppress the HIF-1? pathwayOana R Gottschald
Department of Internal Medicine II, Justus Liebig University, D 35392 Giessen, Germany
J Mol Cell Biol 2:345-56. 2010..In sum, rapid and severe hypoxia caused co-aggregation of TIAR/TIA-1 and these proteins suppressed HIF-1? expression...
