J Gleitz

Summary

Affiliation: University of Ulm
Country: Germany

Publications

  1. ncbi Anticonvulsive action of (+/-)-kavain estimated from its properties on stimulated synaptosomes and Na+ channel receptor sites
    J Gleitz
    University Clinics Ulm, Institute of Naturheilkunde, Germany
    Eur J Pharmacol 315:89-97. 1996
  2. ncbi Influence of extracellular K+ concentration on the time-course of Na+/K+-ATPase inhibition by cardiac glycosides with fast and low binding kinetics
    J Gleitz
    University Clinics Ulm, Institute of Naturheilkunde, Germany
    Eur J Pharmacol 335:89-97. 1997
  3. ncbi Aconitum sp. alkaloids: the modulation of voltage-dependent Na+ channels, toxicity and antinociceptive properties
    J Friese
    Institute of Naturheilkunde, University Clinics Ulm, Germany
    Eur J Pharmacol 337:165-74. 1997
  4. ncbi The alkaloid 6-benzoylheteratisine inhibits voltage-gated Na+ channels in rat brain synaptosomes
    U T Gutser
    University Clinics Ulm, Institute of Naturheilkunde, Germany
    Neuropharmacology 37:1139-46. 1998
  5. ncbi Continuous enzyme-linked fluorometric detection of L-(+)-lactate released from rat brain vesicles under anoxic conditions
    J Gleitz
    University Clinics Ulm, Institute of Naturheilkunde, Germany
    J Neurosci Methods 67:97-102. 1996

Detail Information

Publications5

  1. ncbi Anticonvulsive action of (+/-)-kavain estimated from its properties on stimulated synaptosomes and Na+ channel receptor sites
    J Gleitz
    University Clinics Ulm, Institute of Naturheilkunde, Germany
    Eur J Pharmacol 315:89-97. 1996
    ..The data suggest an interaction of (+/-)-kavain with voltage-dependent Na+ and Ca2+ channels, thereby suppressing the 4-aminopyridine-induced increase in [Na+]i, [Ca2+]i and the release of endogenous glutamate...
  2. ncbi Influence of extracellular K+ concentration on the time-course of Na+/K+-ATPase inhibition by cardiac glycosides with fast and low binding kinetics
    J Gleitz
    University Clinics Ulm, Institute of Naturheilkunde, Germany
    Eur J Pharmacol 335:89-97. 1997
    ..5 to 14 mM. The results suggest that the magnitude of the K+ antagonism under physiological conditions is only limited by the lifespan of the cardiac glycoside-binding E2P enzyme conformation reduced by K+...
  3. ncbi Aconitum sp. alkaloids: the modulation of voltage-dependent Na+ channels, toxicity and antinociceptive properties
    J Friese
    Institute of Naturheilkunde, University Clinics Ulm, Germany
    Eur J Pharmacol 337:165-74. 1997
    ..These results suggest that the alkaloids can be grouped in Na+ channel activating and blocking compounds, but none of the alkaloids seem to be suitable as analgesics because of the low LD50/ED50 values...
  4. ncbi The alkaloid 6-benzoylheteratisine inhibits voltage-gated Na+ channels in rat brain synaptosomes
    U T Gutser
    University Clinics Ulm, Institute of Naturheilkunde, Germany
    Neuropharmacology 37:1139-46. 1998
    ..The data suggest an inhibitory effect of 6-benzoylheteratisine on voltage-gated Na+ channels as the only target, whereas mechanisms of Na+ and Ca2+ homoeostasis and pathways of glutamate release seem not to be affected by the drug...
  5. ncbi Continuous enzyme-linked fluorometric detection of L-(+)-lactate released from rat brain vesicles under anoxic conditions
    J Gleitz
    University Clinics Ulm, Institute of Naturheilkunde, Germany
    J Neurosci Methods 67:97-102. 1996
    ..The method of fluorometric L-lactate determination was confirmed to be suitable for the detection of L-lactate released under physiological conditions from brain vesicles and seems to be applicable to various cell models...