Research Topics
Genomes and GenesSpecies | A GerberSummaryAffiliation: University of Magdeburg Country: Germany Publications
| Collaborators
|
Detail Information
Publications
Cathepsin K--a marker of macrophage differentiation?F Buhling
Institute of Immunology, Otto von Guericke University Magdeburg, Germany
J Pathol 195:375-82. 2001..Its enzymatic characteristics, particularly its high matrix-degrading activity, suggest that cathepsin K-positive epithelioid cells and multinucleated giant cells are characterized by an enhanced specific proteolytic capability...
Expression of cathepsin K in lung epithelial cellsF Buhling
Institute of Immunology, Institute of Pathology, Department of Pneumology and Critical Care, Magdeburg, Germany
Am J Respir Cell Mol Biol 20:612-9. 1999..These findings demonstrate that bronchial and alveolar epithelial cells are capable of expressing cathepsin K, which could be of considerable importance for remodeling processes of the extracellular matrix in the lung...
Interleukin-6 and transforming growth factor-beta 1 control expression of cathepsins B and L in human lung epithelial cellsA Gerber
Institute of Immunology, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany
J Interferon Cytokine Res 21:11-9. 2001..The proinflammatory cytokine IL-6 induced an upregulation of cathepsin L, whereas TGF-beta 1 suppressed cathepsin B and L expression. Further studies are needed to clarify the mechanism that affects cathepsin B and L expression...
Expression of cathepsins B and L in human lung epithelial cells is regulated by cytokinesA Gerber
Institute of Immunology, Otto von Guericke University Magdeburg, Germany
Adv Exp Med Biol 477:287-92. 2000..In conclusion, gene expression of cathepsins B and L is variable. The cytokines IL-6 and TGF-beta 1 modulate cathepsin gene expression...
Proteasome inhibitors modulate chemokine production in lung epithelial and monocytic cellsA Gerber
Institute of Immunology, Otto von Guericke University, Magdeburg, Germany
Eur Respir J 24:40-8. 2004..In conclusion, it was shown that proteasome inhibitors stimulate interleukin-8 secretion in lung epithelial cells and monocytic cells, thus recruiting neutrophils...
Cathepsin K expression in human lungF Buhling
Inst of Immunology, Otto von Guericke University Magdeburg, Germany
Adv Exp Med Biol 477:281-6. 2000..These data suggest that cathepsin K may play an important role in matrix remodeling of the lung under physiological and pathological conditions...
Investigation of annexin V binding to lymphocytes after extracorporeal photoimmunotherapy as an early marker of apoptosisA Gerber
Institute of Immunology, Otto von Guericke University, Magdeburg, Germany
Dermatology 201:111-7. 2000..Induction of programmed cell death is assumed to be a possible effect of extracorporeal photoimmunotherapy (ECPI)...
Effect of granulocyte colony-stimulating factor treatment on ex vivo neutrophil functions in nonneutropenic surgical intensive care patientsA Gerber
Institute of Immunology, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany
J Interferon Cytokine Res 20:1083-90. 2000..The increased count and activation state of neutrophils were associated with clinical improvement in most of these patients. Thus, G-CSF may be a useful adjuvant treatment for nonneutropenic patients with severely impaired wound healing...
