Claudia Friesen

Summary

Affiliation: University of Ulm
Country: Germany

Publications

  1. ncbi [Overcoming of radiation resistances]
    C Friesen
    Institut fur Rechtsmedizin, Universitat Ulm, Prittwitzstr 6, 89075 Ulm
    Nuklearmedizin 49:S31-6. 2010
  2. ncbi Methadone, commonly used as maintenance medication for outpatient treatment of opioid dependence, kills leukemia cells and overcomes chemoresistance
    Claudia Friesen
    Institute of Legal Medicine, University of Ulm, Ulm, Germany
    Cancer Res 68:6059-64. 2008
  3. ncbi DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin
    Claudia Friesen
    Institute of Legal Medicine, University of Ulm, 89075 Ulm, Germany
    Mol Biol Cell 19:3283-9. 2008
  4. ncbi Activation of intrinsic apoptotic pathway by Re-188 irradiation and paclitaxel in coronary artery smooth muscle cells
    C Friesen
    Department of Nuclear Medicine, University of Ulm, Ulm, Germany
    Q J Nucl Med Mol Imaging 52:289-95. 2008
  5. ncbi Breaking chemoresistance and radioresistance with [213Bi]anti-CD45 antibodies in leukemia cells
    Claudia Friesen
    Nuclear Medicine Clinic, Department of Transfusion Medicine, and University Children s Hospital, University of Ulm, Ulm, Germany
    Cancer Res 67:1950-8. 2007
  6. ncbi 123I-ITdU-mediated nanoirradiation of DNA efficiently induces cell kill in HL60 leukemia cells and in doxorubicin-, beta-, or gamma-radiation-resistant cell lines
    Sven N Reske
    Nuclear Medicine Clinic, Universitat Ulm, Ulm, Germany
    J Nucl Med 48:1000-7. 2007
  7. ncbi Beta-irradiation used for systemic radioimmunotherapy induces apoptosis and activates apoptosis pathways in leukaemia cells
    Claudia Friesen
    University Children's Hospital, Prittwitzstrasse 43, 89075 Ulm, Germany
    Eur J Nucl Med Mol Imaging 30:1251-61. 2003
  8. ncbi Anti-CD45 monoclonal antibody YAML568: A promising radioimmunoconjugate for targeted therapy of acute leukemia
    Gerhard Glatting
    Department of Nuclear Medicine, University Ulm, Ulm, Germany
    J Nucl Med 47:1335-41. 2006
  9. ncbi Natural killer resistance of a drug-resistant leukemia cell line, mediated by up-regulation of HLA class I expression
    Carl Friedrich Classen
    University Children s Hospital Ulm, Prittwitzstrasse 43, D 89070 Ulm, Germany
    Haematologica 88:509-21. 2003
  10. ncbi Multiple Myeloma: Molecular Imaging with 11C-Methionine PET/CT--Initial Experience
    Anja Dankerl
    Department of Nuclear Medicine, University of Ulm, Robert Koch Strasse 8, D 89081 Ulm, Germany
    Radiology 242:498-508. 2007

Collaborators

Detail Information

Publications13

  1. ncbi [Overcoming of radiation resistances]
    C Friesen
    Institut fur Rechtsmedizin, Universitat Ulm, Prittwitzstr 6, 89075 Ulm
    Nuklearmedizin 49:S31-6. 2010
    ....
  2. ncbi Methadone, commonly used as maintenance medication for outpatient treatment of opioid dependence, kills leukemia cells and overcomes chemoresistance
    Claudia Friesen
    Institute of Legal Medicine, University of Ulm, Ulm, Germany
    Cancer Res 68:6059-64. 2008
    ....
  3. ncbi DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin
    Claudia Friesen
    Institute of Legal Medicine, University of Ulm, 89075 Ulm, Germany
    Mol Biol Cell 19:3283-9. 2008
    ..Failure in caspases activation using doxorubicin depends on loss of DNA damage and is due to higher rates of NHEJ-DNA-DBS-repair...
  4. ncbi Activation of intrinsic apoptotic pathway by Re-188 irradiation and paclitaxel in coronary artery smooth muscle cells
    C Friesen
    Department of Nuclear Medicine, University of Ulm, Ulm, Germany
    Q J Nucl Med Mol Imaging 52:289-95. 2008
    ..In this study we examined the molecular mechanisms of the cytotoxic effect of Re-188-mediated beta-irradiation on a SMC culture model compared to that of paclitaxel...
  5. ncbi Breaking chemoresistance and radioresistance with [213Bi]anti-CD45 antibodies in leukemia cells
    Claudia Friesen
    Nuclear Medicine Clinic, Department of Transfusion Medicine, and University Children s Hospital, University of Ulm, Ulm, Germany
    Cancer Res 67:1950-8. 2007
    ....
  6. ncbi 123I-ITdU-mediated nanoirradiation of DNA efficiently induces cell kill in HL60 leukemia cells and in doxorubicin-, beta-, or gamma-radiation-resistant cell lines
    Sven N Reske
    Nuclear Medicine Clinic, Universitat Ulm, Ulm, Germany
    J Nucl Med 48:1000-7. 2007
    ....
  7. ncbi Beta-irradiation used for systemic radioimmunotherapy induces apoptosis and activates apoptosis pathways in leukaemia cells
    Claudia Friesen
    University Children's Hospital, Prittwitzstrasse 43, 89075 Ulm, Germany
    Eur J Nucl Med Mol Imaging 30:1251-61. 2003
    ..Understanding the timing, sequence and molecular pathways of beta-irradiation-mediated apoptosis may allow rational adjustment of chemo- and radiotherapeutic strategies...
  8. ncbi Anti-CD45 monoclonal antibody YAML568: A promising radioimmunoconjugate for targeted therapy of acute leukemia
    Gerhard Glatting
    Department of Nuclear Medicine, University Ulm, Ulm, Germany
    J Nucl Med 47:1335-41. 2006
    ..We evaluated the biodistribution of 111In-labeled anti-CD45 antibody in humans using the rat IgG2a monoclonal antibody YAML568 that recognizes a common CD45 epitope present on all human leukocytes...
  9. ncbi Natural killer resistance of a drug-resistant leukemia cell line, mediated by up-regulation of HLA class I expression
    Carl Friedrich Classen
    University Children s Hospital Ulm, Prittwitzstrasse 43, D 89070 Ulm, Germany
    Haematologica 88:509-21. 2003
    ..Here, we clarify the mechanism underlying cross-resistance of drug-resistant variants of the T-leukemia cell line CEM towards natural killer cells...
  10. ncbi Multiple Myeloma: Molecular Imaging with 11C-Methionine PET/CT--Initial Experience
    Anja Dankerl
    Department of Nuclear Medicine, University of Ulm, Robert Koch Strasse 8, D 89081 Ulm, Germany
    Radiology 242:498-508. 2007
    ..To prospectively assess molecular imaging of multiple myeloma (MM) by using the radiolabeled amino acid carbon 11 ((11)C) methionine and positron emission tomography (PET)/computed tomography (CT)...
  11. ncbi Synthesis and evaluation of a radiometal-labeled macrocyclic chelator-derivatised thymidine analog
    Michaela Schmid
    Department of Nuclear Medicine, University Hospital Ulm, 89081 Ulm, Germany
    Nucl Med Biol 33:359-66. 2006
    ..The absence of substrate specificity may be due to the bulky macrocyclic chelator and partial charges remaining on the coordination sphere due to a more complex solution structure...
  12. ncbi Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2
    Ulrich Pannicke
    Institute for Transfusion Medicine, University of Ulm, Ulm, Germany
    Nat Genet 41:101-5. 2009
    ..These observations suggest that reticular dysgenesis is the first example of a human immunodeficiency syndrome that is causally linked to energy metabolism and that can therefore be classified as a mitochondriopathy...
  13. ncbi Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy
    K Stahnke
    Department of Pediatrics, University Children's Hospital, Ulm, Germany
    Blood 98:3066-73. 2001
    ....