Research Topics
| S ChrubasikSummaryAffiliation: University of Freiburg Country: Germany Publications
| Collaborators
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Detail Information
Publications
Harpgophytum procumbens for osteoarthritis and low back pain: a systematic reviewJoel J Gagnier
Department of Health Policy Management and Evaluation, University of Toronto, Faculty of Medicine, Toronto, Canada
BMC Complement Altern Med 4:13. 2004..The objective of this review is to determine the effectiveness of Harpagophytum procumbens preparations in the treatment of various forms of musculoskeletal pain...- Efficacy of a benzocaine lozenge in the treatment of uncomplicated sore throatSigrun Chrubasik
Institute of Forensic Medicine, University of Freiburg, Albertstr 9, 79104, Freiburg, Germany
Eur Arch Otorhinolaryngol 269:571-7. 2012..Adverse events were not observed. Benzocaine lozenges are superior to placebo lozenges and a useful, well-tolerated treatment option to reduce painful pharyngeal discomfort... - A 1-year follow-up after a pilot study with Doloteffin for low back painS Chrubasik
Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
Phytomedicine 12:1-9. 2005..To complete a year's follow-up on patients from a 6-week double-blind pilot comparison between 44 Doloteffin patients and 44 rofecoxib patients being treated for acute exacerbations of chronic low back pain... - Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profilesS Chrubasik
Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
Phytomedicine 12:684-701. 2005..Pharmacokinetic data are only available for [6]-gingerol and zingiberene. Preclinical safety data do not rule out potential toxicity, which should be monitored especially following ginger consumption over longer periods... - [Devil's claw extract as an example of the effectiveness of herbal analgesics]S Chrubasik
Institut für Rechtsmedizin der Universität Freiburg
Orthopade 33:804-8. 2004..Treatment with devil's claw extract is associated with a lower risk of adverse events than treatment with synthetic analgesics, and may contribute in the majority of patients to the relief of pain... - Efficacy and tolerability of potato juice in dyspeptic patients: a pilot studyS Chrubasik
Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
Phytomedicine 13:11-5. 2006..However, placebo-controlled studies with a longer treatment period are needed to confirm this... - The quality of clinical trials with Harpagophytum procumbensS Chrubasik
Department of Forensic Medicine, University of Freiburg, Freiburg, Germany
Phytomedicine 10:613-23. 2003..To examine systematically the quality of the clinical trials investigating the effectiveness of Harpagophytum products... - Expressing treatment-associated changesS Chrubasik
Institute of Forensic Medicine, University of Freiburg, 79104 Freiburg, Germany
Z Rheumatol 64:423-7. 2005..Until they do, authors should justify their choice of expression, particularly if it critically influences their conclusion, and/or present their data as fully as possible on a website... - Patient-perceived benefit during one year of treatment with DoloteffinS Chrubasik
Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
Phytomedicine 14:371-6. 2007..Adverse events were few and none were serious... - A randomized double-blind pilot study comparing Doloteffin and Vioxx in the treatment of low back painS Chrubasik
Department of Forensic Medicine, University of Freiburg, 79104 Freiburg, Germany
Rheumatology (Oxford) 42:141-8. 2003.... - The clinical effectiveness of chokeberry: a systematic reviewC Chrubasik
Braun School of Public Health, Hadassah Medical Center, Hebrew University, Jerusalem, Israel
Phytother Res 24:1107-14. 2010.... - Effectiveness and safety of topical capsaicin cream in the treatment of chronic soft tissue painS Chrubasik
Institute of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
Phytother Res 24:1877-85. 2010..The results indicate that capsaicin cream is useful in patients with chronic soft tissue pain and is also efficacious in patients with chronic back pain for which effectiveness was already demonstrated in earlier clinical trials... - Comparison of outcome measures during treatment with the proprietary Harpagophytum extract doloteffin in patients with pain in the lower back, knee or hipS Chrubasik
Department of Forensic Medicine, University of Freiburg, Germany
Phytomedicine 9:181-94. 2002..Between 50% and 70% of the patients benefitted from Doloteffin with few adverse effects. Thus, Doloteffin is well worth considering for osteoarthritic knee and hip pain and nonspecific low back pain... - Potential economic impact of using a proprietary willow bark extract in outpatient treatment of low back pain: an open non-randomized studyS Chrubasik
Institut fur Rechtsmedizin, University of Freiburg, Germany
Phytomedicine 8:241-51. 2001..Substituting established NSAIDs with COX-2 inhibitors might reduce the side effects, but at greater cost than with the Assalix... - A one-year survey on the use of a powder from Rosa canina lito in acute exacerbations of chronic painC Chrubasik
Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
Phytother Res 22:1141-8. 2008..There were no serious adverse events. The rose hip and seed powder, Litozin, seems to deserve further, more definitive studies as a possible option in long-term management of NSLBP with or without osteoarthritic pain... - Evidence of effectiveness of herbal antiinflammatory drugs in the treatment of painful osteoarthritis and chronic low back painJ E Chrubasik
Institute of Forensic Medicine, University of Freiburg im Breisgau, Albertstr 9 79104 Freiburg im Breisgau, Germany
Phytother Res 21:675-83. 2007.... - The evidence for clinical efficacy of rose hip and seed: a systematic reviewC Chrubasik
Institute of Forensic Medicine, University of Freiburg i.Br, Albertstr. 9, 79104 Freiburg i.Br, Germany
Phytother Res 20:1-3. 2006..CONCLUSIONS: Moderate evidence exists for the use of a powder of the seeds and husks of a Rosa canina subspecies in patients suffering from osteoarthritis... - Physicochemical properties of harpagoside and its in vitro release from Harpagophytum procumbens extract tabletsS Chrubasik
Institut fur Pharmazeutische Biologie, University of Heidelberg, Germany
Phytomedicine 6:469-73. 2000..5 mg of harpagoside per dose. Harpagoside content decreased by about 10% in artificial gastric fluid within a period of 3 hours and remained stable in artificial intestinal fluid for a period of 6 hours... - Effects of an ethanolic salix extract on the release of selected inflammatory mediators in vitroB L Fiebich
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
Phytomedicine 11:135-8. 2004..Our data further suggest that the proprietary Salix extract is a weak inhibitor of proinflammatory cytokines... - Treatment of low back pain with a herbal or synthetic anti-rheumatic: a randomized controlled study. Willow bark extract for low back painS Chrubasik
Herbal Medicines Research and Education Centre, University of Sydney, Sydney, NSW 2006, Australia
Rheumatology (Oxford) 40:1388-93. 2001..Treatment with rofecoxib was about 40% more expensive than that with Assalix. CONCLUSION: There was no significant difference in effectiveness between the two treatments at the doses chosen. Treatment with Assalix was less expensive... - Effectiveness of devil's claw for osteoarthritisS Chrubasik
Rheumatology (Oxford) 41:1332-3; author reply 1333. 2002 - Systematic review on the safety of Harpagophytum preparations for osteoarthritic and low back painJ Vlachojannis
Department of Orthodontics, Columbia University, 630 W 168th, VC 9, Rm 219 B 10032 NYC, NY, USA
Phytother Res 22:149-52. 2008..Since the dosage used in most of the studies is at the lower limit and since long-term treatment with Harpagophytum products is advisable, more safety data are urgently needed... - Impact of herbal medicines on physical impairmentC Chrubasik
Abteilung für Rheumatologie und klinische Immunologie, Kerckhoff Klinik Bad Nauheim Lehrstuhl für Innere Medizin mit Schwerpunkt Rheumatologie der Justus Liebig Universität Giessen, Benekestr 2 8, D 61231 Bad Nauheim, Germany
Phytomedicine 15:536-9. 2008..There may be little to lose from omitting the time-consuming assessments of "physical impairment" in studies of the (primarily analgesic) effectiveness of herbal preparations... - Different views of health care professionals on the treatment of osteoarthritis including low back painS Chrubasik
Rheumatology (Oxford) 42:1020-1. 2003 - Effectiveness of Petasites hybridus preparations in the prophylaxis of migraine: a systematic reviewR Agosti
Headache Center Hirslanden, Münchhaldenstr 33, 8008 Zurich, Switzerland
Phytomedicine 13:743-6. 2006.... - Further evidence on the effectiveness of potato juice in dyspeptic complaintsS Chrubasik
Phytomedicine 13:596-7. 2006 - Potential molecular basis of the chondroprotective effect of Harpagophytum procumbensJ E Chrubasik
Phytomedicine 13:598-600. 2006 - Addendum to the ESCOP monograph on Harpagophytum procumbensS Chrubasik
Phytomedicine 11:691-5; author reply 696. 2004 - Addendum to a recent systematic review on gingerS Chrubasik
Forsch Komplementarmed Klass Naturheilkd 12:168; author reply 168-9. 2005 - [Effectiveness of herbal drugs]S Chrubasik
Forsch Komplementarmed Klass Naturheilkd 10:40-1. 2003 - Vitamin E for rheumatoid arthritis or osteoarthritis: low evidence of effectivenessS Chrubasik
Z Rheumatol 62:491. 2003 - Harpagophytum extractsS Chrubasik
Clin Pharmacol Ther 71:104-5. 2002