Research Topics
Species | Hans-Konrad BiesalskiSummaryAffiliation: University of Hohenheim Country: Germany Publications
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Detail Information
Publications
The importance of beta-carotene as a source of vitamin A with special regard to pregnant and breastfeeding womenManuela Strobel
Nutrition and Food Security, Gronau, Germany
Eur J Nutr 46:I1-20. 2007..For them, recommendations to be aware of potential nutrient intake inadequacies might prove useful...- Vitamin D recommendations: beyond deficiencyHans K Biesalski
Department of Biological Chemistry and Nutrition, Food Security Center, University of Hohenheim, Stuttgart, Germany
Ann Nutr Metab 59:10-6. 2011..Consequently, it should be strongly recommended to increase the intake of vitamin D and to ensure a daily intake of vitamin A as counseled... - Reexamination of a meta-analysis of the effect of antioxidant supplementation on mortality and health in randomized trialsHans K Biesalski
Department of Biological Chemistry and Nutritional Science, University of Hohenheim, Garbenstrasse 28, D 70593 Stuttgart, Germany
Nutrients 2:929-49. 2010..These results suggest that analyses of potential risks from antioxidant supplementation should be placed in the context of a benefit/risk ratio... - Diabetes preventive components in the Mediterranean dietHans K Biesalski
Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstrasse 12, 70593 Stuttgart, Germany
Eur J Nutr 43:I/26-30. 2004..Based on recent studies from the nurses health and physicians health study, a diet which is similar to the Mediterranean diet, physical exercise and a BMI < 25 protects from the development of diabetes type 2... - New aspects in vitamin a metabolism: the role of retinyl esters as systemic and local sources for retinol in mucous epitheliaHans K Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, FRG
J Nutr 134:3453S-3457S. 2004..In conclusion, topically applied retinyl esters may be a promising therapy for local retinol deficiencies and may reverse the morphological alterations of the epithelium in tissues that are vitamin A deficient... - The significance of vitamin A for the development and function of the lungH K Biesalski
University of Hohenheim, Institute 140, Stuttgart, Germany
Forum Nutr 56:37-40. 2003 - NutritargetingH K Biesalski
University of Hohenheim, Institute 140, Stuttgart, Germany
Forum Nutr 56:200-2. 2003 - Antioxidant therapy in critical care--is the microcirculation the primary target?Hans Konrad Biesalski
Department of Biological Chemistry and Nutrition, University Hohenheim, Germany
Crit Care Med 35:S577-83. 2007..Therefore, a significant body of pharmacologic evidence and sound preliminary clinical evidence supports the biological feasibility of using the exemplary antioxidant, vitamin C, in the treatment of the critically ill... - Polyphenols and inflammation: basic interactionsHans K Biesalski
Department of Biological Chemistry and Nutrition, University Hohenheim, Stuttgart, Germany
Curr Opin Clin Nutr Metab Care 10:724-8. 2007..This review summarizes recent papers dealing with the effect of polyphenols on modulators of the inflammatory cascade... - Parenteral ascorbic acid in haemodialysis patientsHans K Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Curr Opin Clin Nutr Metab Care 11:741-6. 2008..The review summarizes recent findings of the effects of parenteral ascorbic acid and discusses toxicological effects... - Bioactive compounds: safety and efficacyHans Konrad Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Nutrition 25:1206-11. 2009.... - Bioactive compounds: definition and assessment of activityHans Konrad Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Nutrition 25:1202-5. 2009..The explicatory text accompanying the short answers was produced and agreed on after the conference and was backed up by corresponding references... - Vitamin E requirements in parenteral nutritionHans K Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Gastroenterology 137:S92-104. 2009..Randomized clinical trials are performed using special formulations of vitamin E solutions because vitamin E is available only in lipid emulsions to protect lipids, but not in an isolated solution for parenteral supply... - 26th Hohenheim Consensus Conference, September 11, 2010 Scientific substantiation of health claims: evidence-based nutritionHans Konrad Biesalski
Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Nutrition 27:S1-20. 2011..The objective was to define the term evidence based nutrition on the basis of expert discussions and scientific evidence... - Hohenheimer Consensus Talk. Oxidative and premature skin ageingH K Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstr 12, 70593 Stuttgart, Germany
Exp Dermatol 12:3-15. 2003..There was a special focus on prevention and intervention of skin ageing with nutrition. Finally, the paper summarizes the scientific background from different areas related to oxidative and premature skin ageing... - Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol binding proteinH K Biesalski
Department of Biological Chemistry and Nutrition, University Hohenheim, Stuttgart, Germany
Am J Clin Nutr 69:931-6. 1999..In addition, other factors associated with low retinol concentrations (eg, low plasma transthyretin or zinc concentrations or mutations in the transthyretin gene) were not present. Neither sibling had a history of systemic disease... - Retinyl palmitate supplementation by inhalation of an aerosol improves vitamin A status of preschool children in Gondar (Ethiopia)H Biesalski
Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Br J Nutr 82:179-82. 1999..01) and 97.3 (SD 31.2) mg/l (P < 0.05) 3 months after supplementation with retinyl palmitate, suggesting that this novel method of delivery of retinyl palmitate by inhalation is effective in improving vitamin A status... - Photoprotection of UV-irradiated human skin: an antioxidative combination of vitamins E and C, carotenoids, selenium and proanthocyanidinsAnne Katrin Greul
Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Skin Pharmacol Appl Skin Physiol 15:307-15. 2002..This might be important for future recommendations for immediate suppression of the early phase of UV-induced erythema, that means pharmacological prevention of sunburn reaction as well as subsequent chronic skin damage... - UV light, beta-carotene and human skin--beneficial and potentially harmful effectsH K Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Arch Biochem Biophys 389:1-6. 2001..At present, there is an ongoing debate on the protective or potentially harmful role of beta-carotene in human skin... - Topical application of vitamin A reverses metaplasia of rat vaginal epithelium: a rapid and efficient approach to improve mucosal barrier functionH K Biesalski
University of Hohenheim, Department of Biological Chemistry and Nutrition, Fruwirthstr 12, D 70593 Stuttgart, Germany
Eur J Med Res 6:391-8. 2001..025) increase in the protection time. These data demonstrate that squamous changes induced by vitamin A deficiency can be totally reversed with topically applied retinyl palmitate... - Free radical theory of agingHans K Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, D 70593 Stuttgart, Germany
Curr Opin Clin Nutr Metab Care 5:5-10. 2002.... - Meat and cancer: meat as a component of a healthy dietH K Biesalski
Department of Biological Chemistry and Nutrition, University Hohenheim, Stuttgart, Germany
Eur J Clin Nutr 56:S2-11. 2002..The latter can be optimized by a diet containing fruit and vegetables, which contain hundreds of more or less proven bioactive constituents, many of them showing antioxidative and anticarcinogenic effects in vitro... - Lycopene inhibits disease progression in patients with benign prostate hyperplasiaSilke Schwarz
University of Hohenheim, Institute of Biological Chemistry and Nutrition, 70593 Stuttgart, Germany
J Nutr 138:49-53. 2008..In conclusion, lycopene inhibited progression of BPH... - The effect of beta-carotene on the expression of interleukin-6 and heme oxygenase-1 in UV-irradiated human skin fibroblasts in vitroU C Obermüller-Jevic
Department of Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstrasse 12, 70593, Stuttgart, Germany
FEBS Lett 509:186-90. 2001..In UVB-irradiated cells, beta-carotene did not modulate levels of IL-6 and HO-1. The observed effects might be relevant for UV-induced inflammatory processes... - [Antioxidants - no reason for a reassessment]H K Biesalski
, Garbenstrasse 30, 70593 Stuttgart, Deutschland
Ophthalmologe 104:618-9. 2007 - Importance of vitamin-A for lung function and developmentH K Biesalski
Department of Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstr 12, Stuttgart D 70593, Germany
Mol Aspects Med 24:431-40. 2003.... - Long-term sequelae of HFE deletion in C57BL/6 x 129/O1a mice, an animal model for hereditary haemochromatosisA Lebeau
Pathologisches Institut, Ludwig Maximilians Universitat, Munchen, Germany, Universitat Hohenheim, Stuttgart, Germany
Eur J Clin Invest 32:603-12. 2002..HFE knockout mice (C57BL/6 x 129/Ola strain) mimic the functional aberrations of human hereditary haemochromatosis (HH) in short-term experiments. The present study investigates functional and morphological long-term changes... - Uptake of vitamin A in buccal mucosal cells after topical application of retinyl palmitate: a randomised, placebo-controlled and double-blind trialU Sobeck
University of Hohenheim, Department of Biological Chemistry and Nutrition, Fruwirthstrasse 12, D-70593 Stuttgart, Germany
Br J Nutr 90:69-74. 2003..05) increase of plasma retinol after 17 d was demonstrated in our present study. The uptake of retinyl palmitate and the following hydrolysis to retinol led to an enrichment of vitamin A in buccal mucosal cells... - [Antioxidants--helpful or harmful?]H K Biesalski
Institut fur Biologische Chemie und Ernahrungswissenschaft, Universitat Hohenheim, Stuttgart, Germany
Ther Umsch 64:135-9. 2007..Whether the consumer may have a benefit from fortified food has not yet been evaluated with respect to antioxidant vitamins... - Relation of DDT residues to plasma retinol, alpha-tocopherol, and beta-carotene during pregnancy and malaria infection: a case-control study in Karen women in northern ThailandW Stuetz
Institute of Biological Chemistry and Nutrition, University of Hohenheim, 70599 Stuttgart, Germany
Sci Total Environ 363:78-86. 2006..51, p<0.001). Plasma alpha-tocopherol and beta-carotene seemed not to be affected by DDT residues... - A modified system to evaluate the potency of anti-oxidative compounds in different cell types in vitroD Mayer
IIIrd Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Eur J Med Res 6:201-8. 2001..As this method was established on 24- and 48-well plates in other cell lines (Caco-2, HFP-1), too, screening of a large array of antioxidative compounds in different cell lines can be performed... - Nutrition and aging: a consensus statementC J Bates
Institut fur Biologische Chemie und Ernahrungswissenschaft, Universtat Hohenheim, Stuttgart, Germany
J Nutr Health Aging 6:103-16. 2002..The encouraging of better nutrition and the taking of exercise is a cost-effective way of decreasing the incidence and progression of age-related disease. The earlier such interventions are introduced the better... - Dietary intake and nutritional status of women and pre-school children in the Republic of the MaldivesA M Golder
Institute of Biological Chemistry and Nutrition, University of Hohenheim, Garbenstrasse 30, D-70599 Stuttgart, Germany
Public Health Nutr 4:773-80. 2001..Higher intakes of locally available vegetables and fruits and fat (especially for children) on a regular basis might reverse the deficits documented on the atolls... - Determination of vitamin A palmitate in buccal mucosal cells: a pilot studyU Sobeck
University of Hohenheim, Department of Biological Chemistry and Nutrition, Fruwirthstr. 12, D-70593 Stuttgart, Germany
Eur J Med Res 7:287-9. 2002..In this way metaplastic alterations of the buccal mucosal epithelium might be prevented or reversed by the application of topical retinyl palmitate... - Improved method for rapid determination of vitamin A in small samples of breast milk by high-performance liquid chromatographyM Strobel
Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
J Chromatogr A 898:179-83. 2000..The simple extraction and separation steps allow a high throughput screening under routine laboratory conditions... - Possible protective effects of alpha-tocopherol on enhanced induction of reactive oxygen species by 2-methoxyestradiol in tumorsOliver Thews
Adv Exp Med Biol 566:349-55. 2005..Inhibition of SOD during ROS-generating hyperthermia results in pronounced cell injury and an improved local tumor control whereas exogenously applied vitamin E seems not to have an impact on oxidative stress... - In vitro reproduction of clinical hallmarks of eczematous dermatitis in organotypic skin modelsKarin Engelhart
BioTeSys GmbH, Schelztorstrasse 54 56, 73728 Esslingen, Germany
Arch Dermatol Res 297:1-9. 2005..Furthermore it can be concluded that these models make it possible to investigate targets of therapeutics in skin...