Research Topics
Genomes and Genes
Species | Kristin BauerSummaryAffiliation: University of Rostock Country: Germany Publications
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Detail Information
Publications
Perforin deficiency attenuates collagen-induced arthritisKristin Bauer
Institute of Immunology, University of Rostock, Rostock, Germany
Arthritis Res Ther 7:R877-84. 2005..Thus, pfp-mediated cytotoxicity is involved in the initiation of tissue damage in arthritis, but pfp-independent cytotoxic death pathways might also contribute to CIA...
Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritisXinhua Yu
Immunogenetics Group, University of Rostock, Schillingallee, 18055 Rostock, Germany
Arthritis Res Ther 9:R3. 2007..Of these 117 genes, 21 were located inside the support intervals of the 8 small-effect QTL and thus were considered as candidate genes...
Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross lineXinhua Yu
Immunogenetics Group, University of Rostock, Rostock, Germany
J Immunol 177:7042-9. 2006..In addition, this study revealed that Cia27 and Trmq3 controlling anti-CII IgG2a Ab and CD4:CD8 T cell ratio, respectively, also regulated CIA clinical phenotypes...
Identification of new quantitative trait loci in mice with collagen-induced arthritisKristin Bauer
Institute for Immunology, University of Rostock, Schillingallee 70, 18055 Rostock, Germany
Arthritis Rheum 50:3721-8. 2004..This study sought to identify potential genetic regulatory mechanisms of CIA in major histocompatibility complex-matched (H2-q) F(2) hybrid mice...
Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in miceMalin Hultqvist
Section for Medical Inflammation Research, Lund University, Lund, Sweden
J Immunol 179:1431-7. 2007..This is important as we, for the first time, can follow the effect of ROS on molecular mechanisms where T cells are responsible for either protection or promotion of arthritis depending on the level of oxygen species produced...
Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinomaJoseph Riss
Laboratory of Biosystems and Cancer, Comparative Oncology Program, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Res 66:7216-24. 2006..The observations reported here provide a conceptual framework for further efforts to understand the biology and to develop more effective diagnostic biomarkers and therapeutic strategies for renal tumors and renal ischemia...
