Research Topics
| Gunnar TepeSummaryCountry: Germany Publications
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Detail Information
Publications
Local delivery of paclitaxel to inhibit restenosis during angioplasty of the legGunnar Tepe
Radiologische Klinik, Diagnostische und Interventionelle Radiologie, Eberhard Karls Universitat, Tubingen, Germany
N Engl J Med 358:689-99. 2008..We investigated the use of paclitaxel-coated angioplasty balloons and paclitaxel dissolved in the angiographic contrast medium during angioplasty of the leg...- GP IIb/IIIa blockade during peripheral artery interventionsGunnar Tepe
Department of Diagnostic Radiology, University of Tubingen, 72076, Tubingen, Germany
Cardiovasc Intervent Radiol 31:8-13. 2008..This article summarizes the action and differences of GP Ilb/IIIa receptor inhibitors and its possible indication in peripheral arteries... - Economic value of thrombolysis with adjunctive abciximab in patients with subacute peripheral arterial occlusionStephan H Duda
Division of Diagnostic Radiology, Department of Radiology, University of Tuebingen, Dr Eberhard Karls University, Germany
Pharmacoeconomics 20:203-13. 2002..This analysis evaluates the economic impact of abciximab, a GP IIb/IIIa inhibitor, as an adjunct to urokinase in peripheral artery occlusions of less than 6 weeks duration... - Reduction of intimal hyperplasia with Re-188-labeled stents in a rabbit model at 7 and 26 weeks: an experimental studyGunnar Tepe
Department of Diagnostic Radiology, University of Tubingen, Tubingen, Germany
Cardiovasc Intervent Radiol 28:632-7. 2005..188)Re stents were capable to reduce intimal hyperplasia and did not cause thrombosis. The edge effect, which was the major limitation of (32)P stents, was not observed in (188)Re stents... - Silicon carbide coating of nitinol stents to increase antithrombogenic properties and reduce nickel releaseJörg M Schmehl
Department of Diagnostic Radiology, University Hospital of Tuebingen, D 72076 Tuebingen, Germany
Cardiovasc Revasc Med 9:255-62. 2008..A reduction of thrombogenicity can be achieved by passive coating with silicon carbide, which induces less thrombus formation due to its semiconducting properties... - Technical report and preliminary clinical data of a novel catheter for luminal re-entry after subintimal dissectionBenjamin Wiesinger
Department of Diagnostic Radiology, University of Tuebingen, Tuebingen, Germany
Invest Radiol 40:725-8. 2005..The objective of this study was to evaluate the safety and the effectiveness of the Outback catheter for intraluminal re-entry after subintimal dissection in the crossing of chronic arterial occlusions... - Prevention of carotid artery restenosis after sirolimus-coated stent implantation in pigsGunnar Tepe
Department of Diagnostic Radiology, University of Tuebingen, Germany
Stroke 37:492-4. 2006..Even though the restenosis rate in CA is reported to be lower than in the coronary and peripheral arteries, problems may arise with increasing numbers of treated patients and lengthier follow-up... - Superficial femoral artery: current treatment optionsGunnar Tepe
Department of Diagnostic Radiology, University of Tuebingen, Hoppe Seyler Strasse 3, 72076 Tuebingen, Germany
Eur Radiol 16:1316-22. 2006..This manuscript should summarize the hopes and limitations of different approaches such as brachytherapy, cutting balloons, stents and stent grafts, drug-eluting stents, and drug-coated balloons... - Evaluation of various image reconstruction parameters in lower extremity stents using multidetector-row CT angiography: initial findingsMartin Heuschmid
Department of Diagnostic Radiology, University Hospital Tuebingen, Eberhard Karls University, Hoppe Seyler Strasse 3, 72076 Tuebingen, Germany
Eur Radiol 17:265-71. 2007..Therefore, MDCT could be a valuable non-invasive modality for stent imaging in the peripheral vasculature... - Drug-eluting stents for infrainguinal occlusive disease: progress and challengesGunnar Tepe
Department of Diagnostic Radiology, University of Tuebingen, Tuebingen, Germany
Semin Vasc Surg 19:102-8. 2006..This article summarizes the special role of the superficial femoral artery in restenosis, with efforts being made to reduce the restenosis rate in this artery, focusing on stents and drug-eluting stents... - Self-expanding nitinol stents for treatment of infragenicular arteries following unsuccessful balloon angioplastyGunnar Tepe
Department of Diagnostic Radiology, University of Tuebingen, Hoppe Seyler Str 3, 72076 Tuebingen, Germany
Eur Radiol 17:2088-95. 2007..The use of self-expanding nitinol stents in tibioperoneal and popliteal arteries is a safe and feasible option for the treatment of unsuccessful PTA. The 6-months patency is high... - Isotropic high-spatial-resolution contrast-enhanced 3.0-T MR angiography in patients suspected of having renal artery stenosisUlrich Kramer
Department of Diagnostic Radiology, University of Tuebingen, Hoppe Seyler Str 3, 72076 Tuebingen, Germany
Radiology 247:228-40. 2008..Owing to its high sensitivity, contrast-enhanced 3-T MR angiography can be used reliably to exclude RAS and can serve as a useful screening method in the diagnostic work-up of patients with arterial hypertension... - Current status of bare and drug-eluting stents in infrainguinal peripheral vascular diseaseJörg Schmehl
Department of Diagnostic Radiology, University of Tuebingen, Hoppe Seyler Str 3, D 72076 Tuebingen, Germany
Expert Rev Cardiovasc Ther 6:531-8. 2008..Furthermore, endovascular therapy of below-the-knee lesions is becoming an increasingly interesting area for interventional procedures... - Aortic dissection mimicking subarachnoidal hemorrhageBoris Nohé
Department of Anaesthesiology and Intensive Care Medicine, Eberhard Karls University Tubingen, Germany
Anesth Analg 101:233-4, table of contents. 2005.... - Complication after embolization of a complex renal vascular malformationBenjamin Wiesinger
Department of Diagnostic Radiology, Hoppe Seylerstr. 3, , Germany
Nephrol Dial Transplant 20:1729-33. 2005 - PTFE-covered self-expanding nitinol stents for the treatment of severe iliac and femoral artery stenoses and occlusions: final results from a prospective studyBenjamin Wiesinger
Division of Diagnostic Radiology, Department of Radiology, University of Tubingen, Germany
J Endovasc Ther 12:240-6. 2005..To evaluate the technical performance, safety, and 1-year clinical efficacy of polytetrafluoroethylene (PTFE)-covered nitinol stents in the treatment of atherosclerotic iliac and superficial femoral artery (SFA) disease... - Drug-eluting stents: potential applications for peripheral arterial occlusive diseaseStephan H Duda
Department of Diagnostic Radiology, University of Tuebingen, Germany
J Vasc Interv Radiol 14:291-301. 2003..This article will give an overview of experimental and clinical data of the different agents in published and ongoing trials... - Frequent embolization in peripheral angioplasty: detection with an embolism protection device (AngioGuard) and electron microscopyClaudius W König
Department of Diagnostic Radiology, University of Tuebingen, Hoppe Seyler Strasse 3, 72076 Tuebingen, Germany
Cardiovasc Intervent Radiol 26:334-9. 2003..To evaluate the deliverability and protection capabilities of an embolism protection filter in angioplasty of peripheral arteries... - ART-123 Asahi KaseiSascha Khorchidi
Department of Radiology, University of Tubingen, Germany
Curr Opin Investig Drugs 3:1196-8. 2002..By September 2000, it had entered phase III trials [383525]. A patent, US-05916874, claiming a method for treating liver injury and whose composition comprises a thrombomodulin, was published in 1999 by the company... - Thrombogenicity of various endovascular stent types: an in vitro evaluationGunnar Tepe
Department of Diagnostic Radiology, University of Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
J Vasc Interv Radiol 13:1029-35. 2002..The aim of this study was to evaluate the thrombogenicity of different peripheral stent types in a standardized in vitro model with fresh human whole blood... - Stent struts and articulations: their impact on balloon-expandable stents' hoop strength, pushability, and radiopacity in an experimental settingJakub Wiskirchen
Department of Diagnostic Radiology, University Hospital Tubingen, Germany
Invest Radiol 37:356-62. 2002..OBJECTIVES AND RATIONALE: To evaluate the hoop strength, the pushability, and the radiopacity of endovascular stents depending on their design... - Radiopacity of current endovascular stents: evaluation in a multiple reader phantom studyJakub Wiskirchen
Department of Diagnostic Radiology, University of Tubingen, Germany
J Vasc Interv Radiol 15:843-52. 2004..To evaluate the radiopacity of endovascular stents based on the fluoroscopy mode in a phantom of the human pelvis... - The effects of paclitaxel on the three phases of restenosis: smooth muscle cell proliferation, migration, and matrix formation: an in vitro studyJakub Wiskirchen
Department of Diagnostic Radiology, University Hospital Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
Invest Radiol 39:565-71. 2004..We sought to evaluate the growth-modulating potential of paclitaxel on cultured human arterial smooth muscle cells depending on the administered dose... - Endothelin A receptor antagonist LU 135252 inhibits hypercholesterolemia-induced, but not deendothelialization-induced, atherosclerosis in rabbit arteriesGunnar Tepe
Department of Diagnostic Radiology, University of Tubingen, Germany
Invest Radiol 37:349-55. 2002..The purpose of the study was to test the capability of the endothelin A receptor antagonist LU 135252 to reduce neointimal formation in rabbits after balloon denudation with and without the presence of hypercholesterolemia... - Peripheral arteries: treatment with antibodies of platelet receptors and reteplase for thrombolysis--APART trialGunnar Tepe
Department of Diagnostic Radiology, University of Tubingen, Tubingen, Germany
Radiology 239:892-900. 2006.... - Management of chronic low back pain: rationales, principles, and targets of imaging-guided spinal injectionsJan Fritz
Department of Diagnostic Radiology, Eberhard Karls University, Hoppe Seyler Str 3, Tubingen, Germany
Radiographics 27:1751-71. 2007..Therapeutic injections also may help hasten the recovery of patients with persistent or recurrent pain after spinal surgery... - Nitinol stent implantation versus percutaneous transluminal angioplasty in superficial femoral artery lesions up to 10 cm in length: the femoral artery stenting trial (FAST)Hans Krankenberg
Hamburg University Cardiovascular Center, Hamburg, Germany
Circulation 116:285-92. 2007..The present study was designed to investigate the impact of nitinol stenting of superficial femoral artery lesions with a maximum length of 10 cm on restenosis and clinical outcomes at 1 year... - Inhibition of restenosis in femoropopliteal arteries: paclitaxel-coated versus uncoated balloon: femoral paclitaxel randomized pilot trialMichael Werk
Charite, Universitatsmedizin Berlin, Martin Luther Krankenhaus, Department of Radiology, Berlin, Germany
Circulation 118:1358-65. 2008..The success of percutaneous intervention in peripheral arterial disease is limited by restenosis. The aim of the present pilot study was to evaluate a novel method of local drug delivery... - Drug-eluting and bare nitinol stents for the treatment of atherosclerotic lesions in the superficial femoral artery: long-term results from the SIROCCO trialStephan H Duda
Center for Diagnostic Radiology and Minimally Invasive Therapy, The Jewish Hospital Berlin, Heinz Galinski Strasse 1, 13347 Berlin, Germany
J Endovasc Ther 13:701-10. 2006..To review clinical outcomes of patients with chronic limb ischemia and TASC type C lesions treated with sirolimus-eluting versus bare SMART nitinol self-expanding stents... - Long-term results after directional atherectomy of femoro-popliteal lesionsThomas Zeller
Department of Angiology, Herz Zentrum Bad Krozingen, Bad Krozingen, Germany
J Am Coll Cardiol 48:1573-8. 2006..Our objective in this research was the evaluation of the long-term results after directional atherectomy using the Silverhawk device (FoxHollow Technologies, Redwood City, California) of femoro-popliteal lesions... - Reteplase monotherapy and reteplase/abciximab combination therapy in peripheral arterial occlusive disease: results from the RELAX trialKenneth Ouriel
Department of Vascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Vasc Interv Radiol 15:229-38. 2004..The primary endpoint of this analysis was major bleeding as defined by the Thrombolysis in Myocardial Infarction (TIMI) investigators... - Gadolinium-based contrast media compared with iodinated media for digital subtraction angiography in azotaemic patientsChristiane M Erley
University of Tubingen, Department of Internal Medicine, Section for Nephrology and Hypertension, Germany
Nephrol Dial Transplant 19:2526-31. 2004.... - Evaluation of magnetic navigation in an in vitro model of uterine artery embolizationTobias Dietrich
Department of Diagnostic Radiology, University of Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
J Vasc Interv Radiol 15:1457-62. 2004..To compare steering of a novel magnetic guide wire with a standard 0.014-inch guide wire within a vascular phantom... - Sirolimus-eluting versus bare nitinol stent for obstructive superficial femoral artery disease: the SIROCCO II trialStephan H Duda
Center for Diagnostic Radiology and Minimally Invasive Therapy, The Jewish Hospital Berlin, Heinz Galinski Str 1, 13347 Berlin, Germany
J Vasc Interv Radiol 16:331-8. 2005..To investigate further the safety and efficacy of the sirolimus-eluting S. M.A.R.T. Nitinol Self-expanding Stent by comparison with a bare stent in superficial femoral artery (SFA) obstructions... - Reduced thrombogenicity of nitinol stents--in vitro evaluation of different surface modifications and coatingsGunnar Tepe
Radiology, University of Tubingen, Hoppe-Seyler-Str.3, 72076 Tubingen, Germany
Biomaterials 27:643-50. 2006..The Chandler loop is a valuable tool to test polymeric coatings ex vivo since these modifications may reduce drug performance by inducing inflammatory reaction themselves...