Daniel Summerer

Summary

Country: Germany

Publications

  1. ncbi Enabling technologies of genomic-scale sequence enrichment for targeted high-throughput sequencing
    Daniel Summerer
    febit biomed gmbh, Im Neuenheimer Feld 519, 69120 Heidelberg, Germany
    Genomics 94:363-8. 2009
  2. ncbi Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing
    Daniel Summerer
    febit biomed gmbh, 69120 Heidelberg, Germany
    Genome Res 19:1616-21. 2009
  3. ncbi Targeted high throughput sequencing of a cancer-related exome subset by specific sequence capture with a fully automated microarray platform
    Daniel Summerer
    febit biomed gmbh, Im Neuenheimer Feld 519, 69120 Heidelberg, Germany
    Genomics 95:241-6. 2010
  4. ncbi A flexible and fully integrated system for amplification, detection and genotyping of genomic DNA targets based on microfluidic oligonucleotide arrays
    Daniel Summerer
    Im Neuenheimer Feld, Heidelberg, Germany
    N Biotechnol 27:149-55. 2010
  5. ncbi Targeted next-generation sequencing by specific capture of multiple genomic loci using low-volume microfluidic DNA arrays
    Stephan Bau
    febit biomed gmbh, Im Neuenheimer Feld 519, 69120, Heidelberg, Germany
    Anal Bioanal Chem 393:171-5. 2009
  6. ncbi Specific sequence selection and next generation resequencing of 68 E. coli genes using HybSelect
    Nadine Schracke
    febit biomed gmbh, D 69120 Heidelberg, Germany
    N Biotechnol 26:229-33. 2009

Collaborators

Detail Information

Publications6

  1. ncbi Enabling technologies of genomic-scale sequence enrichment for targeted high-throughput sequencing
    Daniel Summerer
    febit biomed gmbh, Im Neuenheimer Feld 519, 69120 Heidelberg, Germany
    Genomics 94:363-8. 2009
    ..We summarize the different technologies and highlight individual characteristics related to general potential and different suitabilities for specific applications...
  2. ncbi Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing
    Daniel Summerer
    febit biomed gmbh, 69120 Heidelberg, Germany
    Genome Res 19:1616-21. 2009
    ..Analysis of SNP calling accuracies after enrichment revealed excellent concordance, with the reference sequence closely mirroring the previously reported performance of Illumina sequencing conducted without sequence enrichment...
  3. ncbi Targeted high throughput sequencing of a cancer-related exome subset by specific sequence capture with a fully automated microarray platform
    Daniel Summerer
    febit biomed gmbh, Im Neuenheimer Feld 519, 69120 Heidelberg, Germany
    Genomics 95:241-6. 2010
    ..Uniformity was such that >68% of exons had at least half the median depth of coverage. An analysis of reference SNPs revealed a sensitivity of up to 93% and a specificity of 98.2% or higher...
  4. ncbi A flexible and fully integrated system for amplification, detection and genotyping of genomic DNA targets based on microfluidic oligonucleotide arrays
    Daniel Summerer
    Im Neuenheimer Feld, Heidelberg, Germany
    N Biotechnol 27:149-55. 2010
    ..The high automation grade of the system reduces contamination risk and workload and should enhance safety and reproducibility...
  5. ncbi Targeted next-generation sequencing by specific capture of multiple genomic loci using low-volume microfluidic DNA arrays
    Stephan Bau
    febit biomed gmbh, Im Neuenheimer Feld 519, 69120, Heidelberg, Germany
    Anal Bioanal Chem 393:171-5. 2009
    ..6 and 107.5-fold for the individual target regions. This method represents a flexible and cost-effective approach for large-scale resequencing of complex genomes...
  6. ncbi Specific sequence selection and next generation resequencing of 68 E. coli genes using HybSelect
    Nadine Schracke
    febit biomed gmbh, D 69120 Heidelberg, Germany
    N Biotechnol 26:229-33. 2009
    ..The study used Escherichia coli K12 MG1655 as a model organism to test parameters such as method fidelity, capacity or reproducibility as a proof-of-principle...