Research Topics
| C L SchlichtingSummaryAffiliation: School of Medicine Country: Germany Publications
| Collaborators
|
Detail Information
Publications
Dendritic cell endothelium interaction in autoimmunityC L Schlichting
Department of Surgery, Devision of Transplantation Surgery, School of Medicine, University Hospital, University Rostock, Schillingalle 35, 18055 Rostock, Germany
Curr Pharm Des 10:171-81. 2004..In lymph nodes dendritic cells can traffic to T-cell areas where they activate naïve T-cells. Throughout this review we are developing a model of in vivo activation of auto-reactive T-cells by activated dendritic cells...
Dendritic cells as pharmacological targets for the generation of regulatory immunosuppressive effectors. New implications for allo-transplantationC L Schlichting
Department of Surgery, Division of Transplantation Surgery, School of Medicine, University Hospital, University Rostock, Schillingallee 35, 18055 Rostock, Germany
Curr Med Chem 12:1921-30. 2005..Here we review how immunosuppressive agents interfere with DC maturation, migration and homeostasis. We are developing a rational to select different drugs for the generation of regulatory DCs, for allo-transplantation clinical settings...
Dendritic cell adhesion is enhanced on endothelial cells preexposed to calcineurin inhibitorsChristoph L Schlichting
Department of Surgery, Division of Transplantation Surgery, School of Medicine, University Hospital, University Rostock, Rostock, Germany
J Cardiovasc Pharmacol 46:250-4. 2005..We speculate that long-term immunosuppression mediates enhanced invasion of recipient DCs to the donor organ and therefore may aggravate chronic rejection...
Renal ischemia-reperfusion injury: new implications of dendritic cell-endothelial cell interactionsC L Schlichting
Department of Surgery, Division of Transplantation Surgery, School of Medicine, University Hospital, University Rostock, Rostock, Germany
Transplant Proc 38:670-3. 2006..Herein we developed a new allotransplant-rejection model after renal I/R injury...
Involvement of dendritic cells in allograft rejection new implications of dendritic cell-endothelial cell interactionsC L Schlichting
Department of Surgery, Division of Transplantation Surgery, School of Medicine, University Hospital, University Rostock, Schillingallee 35, 18055 Rostock, Germany
Mini Rev Med Chem 7:423-8. 2007..Despite the shortcomings of laboratory animal studies, strong promises are deriving from these studies for clinical kidney, heart, and liver transplantation...
Endothelial determinants of dendritic cell adhesion and migration: new implications for vascular diseasesMichael Weis
Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif, USA
Arterioscler Thromb Vasc Biol 22:1817-23. 2002..A fundamental aspect of DC function is their capacity to adhere and migrate through vascular endothelial cells (ECs). We investigated the role of endothelial activation and dysregulation of the NO pathway on DC adhesion and migration...
Drugs modulating endothelial function after transplantationThomas Nickel
Medizinische Klinik und Poliklinik I, University Hospital Munich-Grosshadern, Ludwig-Maximilians University of Munich, Germany
Transplantation 82:S41-6. 2006..We briefly review the evidence supporting their use as protection for endothelial cells in transplant recipients...
