S H Schirmer

Summary

Country: Germany

Publications

  1. ncbi [Update on anti-platelet therapy]
    S H Schirmer
    Kardiologie, Angiologie und Internistische Intensivmedizin, Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 136:1260-4. 2011
  2. ncbi Novel anticoagulants for stroke prevention in atrial fibrillation: current clinical evidence and future developments
    Stephan H Schirmer
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    J Am Coll Cardiol 56:2067-76. 2010
  3. ncbi Blocking interferon {beta} stimulates vascular smooth muscle cell proliferation and arteriogenesis
    Stephan H Schirmer
    Department of Cardiology, Saarland University Hospital, 66421 Homburg Saar, Germany
    J Biol Chem 285:34677-85. 2010
  4. ncbi Hotlines and clinical trial updates presented at the European Society of Cardiology Meeting 2009: data from RE-LY, PLATO, MADIT-CRT, PROTECT, SYNTAX, TRITON and more
    S H Schirmer
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Clin Res Cardiol 98:691-9. 2009
  5. ncbi Interferon-beta signaling is enhanced in patients with insufficient coronary collateral artery development and inhibits arteriogenesis in mice
    Stephan H Schirmer
    Department of Cardiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
    Circ Res 102:1286-94. 2008
  6. ncbi Suppression of inflammatory signaling in monocytes from patients with coronary artery disease
    Stephan H Schirmer
    Department of Cardiology, Academic Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands
    J Mol Cell Cardiol 46:177-85. 2009
  7. ncbi Stimulation of collateral artery growth: travelling further down the road to clinical application
    S H Schirmer
    Department of Cardiology, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Heart 95:191-7. 2009
  8. ncbi [Mechanisms and potential of the therapeutic stimulation of arteriogenesis]
    S H Schirmer
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 134:302-6. 2009
  9. ncbi [Novel anticoagulants for stroke prevention in atrial fibrillation]
    M Baumhakel
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes
    Dtsch Med Wochenschr 135:2304-8. 2010
  10. ncbi Vascular pathophysiology in response to increased heart rate
    Florian Custodis
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    J Am Coll Cardiol 56:1973-83. 2010

Collaborators

Detail Information

Publications16

  1. ncbi [Update on anti-platelet therapy]
    S H Schirmer
    Kardiologie, Angiologie und Internistische Intensivmedizin, Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 136:1260-4. 2011
    ..This review article summarizes current data on novel platelet inhibitors and delineates their potential influence on clinical practice...
  2. ncbi Novel anticoagulants for stroke prevention in atrial fibrillation: current clinical evidence and future developments
    Stephan H Schirmer
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    J Am Coll Cardiol 56:2067-76. 2010
    ..This review focuses on current advances in the development of directly acting oral anticoagulant drugs and their potential to replace the VKA class of drugs in patients with AF...
  3. ncbi Blocking interferon {beta} stimulates vascular smooth muscle cell proliferation and arteriogenesis
    Stephan H Schirmer
    Department of Cardiology, Saarland University Hospital, 66421 Homburg Saar, Germany
    J Biol Chem 285:34677-85. 2010
    ..Inhibition of IFN? stimulates VSMC proliferation and collateral artery growth...
  4. ncbi Hotlines and clinical trial updates presented at the European Society of Cardiology Meeting 2009: data from RE-LY, PLATO, MADIT-CRT, PROTECT, SYNTAX, TRITON and more
    S H Schirmer
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Clin Res Cardiol 98:691-9. 2009
    ..in Clin Res Cardiol 96:767-786, 2007; Müller et al. in Clin Res Cardiol 97:851-864, 2008)...
  5. ncbi Interferon-beta signaling is enhanced in patients with insufficient coronary collateral artery development and inhibits arteriogenesis in mice
    Stephan H Schirmer
    Department of Cardiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
    Circ Res 102:1286-94. 2008
    ..Inhibition of IFN-beta signaling may serve as a novel approach for the stimulation of collateral artery growth...
  6. ncbi Suppression of inflammatory signaling in monocytes from patients with coronary artery disease
    Stephan H Schirmer
    Department of Cardiology, Academic Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands
    J Mol Cell Cardiol 46:177-85. 2009
    ..Transcriptome differences of circulating cells possibly play less of a role than hitherto thought in the individual patient's susceptibility to atherosclerotic CAD, when appropriately matched for clinical symptoms and medication taken...
  7. ncbi Stimulation of collateral artery growth: travelling further down the road to clinical application
    S H Schirmer
    Department of Cardiology, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Heart 95:191-7. 2009
    ..Future directions in the translation from bench to bedside and potential new approaches to the stimulation of vascular growth are discussed...
  8. ncbi [Mechanisms and potential of the therapeutic stimulation of arteriogenesis]
    S H Schirmer
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 134:302-6. 2009
    ....
  9. ncbi [Novel anticoagulants for stroke prevention in atrial fibrillation]
    M Baumhakel
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes
    Dtsch Med Wochenschr 135:2304-8. 2010
    ..This review addresses the new anticoagulants Apixaban, Rivaroxban and Dabigatranetexilat with the design and as available the results of the corresponding phase-III-trials in atrial fibrillation (ARISTOTLE, ROCKET-AF, RE-LY)...
  10. ncbi Vascular pathophysiology in response to increased heart rate
    Florian Custodis
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    J Am Coll Cardiol 56:1973-83. 2010
    ....
  11. ncbi Leukocyte subpopulations and arteriogenesis: specific role of monocytes, lymphocytes and granulocytes
    Imo E Hoefer
    Research Group for Experimental and Clinical Arteriogenesis, Department of Cardiology, University of Freiburg, Germany
    Atherosclerosis 181:285-93. 2005
    ..The role of these two cell types in arteriogenesis remains yet to be clarified, which was the aim of the current study...
  12. ncbi Design of the START-trial: STimulation of ARTeriogenesis using subcutaneous application of GM-CSF as a new treatment for peripheral vascular disease. A randomized, double-blind, placebo-controlled trial
    Niels van Royen
    Department of Cardiology, University of Amsterdam, The Netherlands
    Vasc Med 8:191-6. 2003
    ..Iliac flow reserve and conductance will be measured by magnetic resonance imaging...
  13. ncbi Local cytokine concentrations and oxygen pressure are related to maturation of the collateral circulation in humans
    Stephan H Schirmer
    Department of Cardiology, Academic Medical Center, University of Amsterdam, The Netherlands
    J Am Coll Cardiol 53:2141-7. 2009
    ..Our aim was to determine cytokine and oxygen gradients over the collateral circulation in humans...
  14. ncbi Anti-tumor necrosis factor-{alpha} therapies attenuate adaptive arteriogenesis in the rabbit
    Sebastian Grundmann
    Department for Internal Medicine III Cardiology and Angiology, University Hospital Freiburg, Freiburg, Germany
    Am J Physiol Heart Circ Physiol 289:H1497-505. 2005
    ..This is the first report showing a negative influence of TNF-alpha inhibitors on collateral artery growth...
  15. ncbi Differential effects of MCP-1 and leptin on collateral flow and arteriogenesis
    Stephan H Schirmer
    Research Group for Experimental and Clinical Arteriogenesis, Department of Internal Medicine III Cardiology and Angiology, University Hospital Freiburg, Breisacher Strasse 66 ZKF, D 79106 Freiburg, Germany
    Cardiovasc Res 64:356-64. 2004
    ....
  16. ncbi Stimulation of collateral artery growth: a potential treatment for peripheral artery disease
    Stephan H Schirmer
    Department of Internal Medicine III Cardiology and Angiology, University Hospital Freiburg, Germany
    Expert Rev Cardiovasc Ther 2:581-8. 2004
    ..This review will critically evaluate the results of preclinical and clinical investigations on the stimulation of vascular growth, focusing specifically on the peripheral circulation...