Research Topics
Species | Andreas LinkSummaryAffiliation: Saarland University Country: Germany Publications
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Publications
Endogenous plasma activated protein C levels and the effect of enoxaparin and drotrecogin alfa (activated) on markers of coagulation activation and fibrinolysis in pulmonary embolismCarl Erik H Dempfle
I Department of Medicine, University Medical Center Mannheim, Theodor Kutzer Ufer, Mannheim D 68167, Germany
Crit Care 15:R23. 2011..There are no published data on the status of endogenous activated protein C (APC) in pulmonary embolism (PE), and no data on the effect of drotrecogin alfa (activated) (DAA) given in addition to therapeutic dose enoxaparin...- Rapid immunomodulation by rosuvastatin in patients with acute coronary syndromeAndreas Link
Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, D 66421Homburg Saar, Germany
Eur Heart J 27:2945-55. 2006..It is unclear how rapidly the beneficial effects of statins occur in patients with ACS and whether these drug properties are related to lipid lowering... - Telmisartan inhibits beta2-integrin MAC-1 expression in human T-lymphocytesAndreas Link
Klinik fur Innere Medizin III, Universitat des Saarlandes, Homburg Saar, Germany
J Hypertens 24:1891-8. 2006..Although pro-inflammatory properties of angiotensin II as well as anti-inflammatory effects of AT1 receptor antagonists are well known, the underlying mechanisms are poorly understood... - Argatroban for anticoagulation in continuous renal replacement therapyAndreas Link
Klinik fur Innere Medizin III, Universitätsklinikum des Saarlandes D 66421Homburg Saar, Germany
Crit Care Med 37:105-10. 2009..The investigation focused on predictors for the maintenance doses of argatroban with efficacy and safety of argatroban being secondary outcomes... - [Hypertensive emergencies]A Link
Klinik fur Innere Medizin III, Universitat des Saarlandes, Homburg
Internist (Berl) 46:557-63. 2005..In hypertensive urgencies no target organ damages occur. For these patients a slow lowering of blood pressure values to normal levels is adequate... - Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shockAndreas Link
Klinik fur Innere Medizin III, Universitat des Saarlandes, 66421 Homburg Saar, Germany
Crit Care 12:R159. 2008.... - [Treatment of peri- and postoperative hypertensive emergencies]A Link
Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, 66421Homburg Saar, Germany
Dtsch Med Wochenschr 134:701-7. 2009..Newer substances (fenoldopam, nicardipine, clevidipine) have promising kinetic properties but are not as yet been approved for antihypertensive treatment in Germany... - Tirofiban preserves platelet loss during continuous renal replacement therapy in a randomised prospective open-blinded pilot studyAndreas Link
Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Kirrberger Strasse, 66421 Homburg Saar, Germany
Crit Care 12:R111. 2008..The reversible platelet glycoprotein IIb/IIIa receptor inhibitor tirofiban was investigated to preserve platelet number and activation in a prospective open-blinded endpoint evaluation study... - Rosuvastatin induces apoptosis in CD4(+)CD28 (null) T cells in patients with acute coronary syndromesAndreas Link
Klinik fur Innere Medizin III, Universitat des Saarlandes, Kirrberger Strasse, 66421, Homburg, Saar, Germany
Clin Res Cardiol 100:147-58. 2011..The aim of this study was to evaluate whether statins decrease the number of circulating CD4(+)CD28(null) T cells by apoptosis in patients with ACS... - Long-term follow-up of early versus delayed invasive approach after fibrinolysis in acute myocardial infarctionYvonne P Clever
Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
Circ Cardiovasc Interv 4:342-8. 2011..The Southwest German Interventional Study in Acute Myocardial Infarction (SIAM III) evaluated the effects of transfer for early PCI in acute ST-elevation-myocardial infarction compared with a delayed PCI strategy... - [Hypersensitivity syndrome during therapy with allopurinol in asymptomatic hyperuricemia with a fatal outcome]B Hammer
Medizinische Klinik und Poliklinik, Innere Medizin III Kardiologie Angiologie, Homburg Saar
Dtsch Med Wochenschr 126:1331-4. 2001..A 86-year-old woman with chronic renal failure was treated with allopurinol for asymptomatic hyperuricemia. After one week she developed quickly progressive exanthema, bullous eruptions, epidermolysis, fever of 39.1; C and dyspnoea at rest... - Role of receptor for advanced glycation end products in cardiogenic shock*Simina Ramona Selejan
From the Klinik für Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
Crit Care Med 40:1513-22. 2012..However, until now, no data exist regarding the role of soluble receptor for advanced glycation end products and receptor for advanced glycation end products in humans with cardiogenic shock complicating myocardial infarction... - [Polymorphonuclear neutrophils in myocardial ischemia and reperfusion injury. Influence of coronary intervention?]Andreas Link
Medizinische Klinik und Poliklinik, Innere Medizin III Universitätskliniken des Saarlandes, 66421 Homburg Saar, Germany
Z Kardiol 93:605-11. 2004..Induction of PMN activation might contribute to the superior outcome following stenting and early intervention compared to conventional PTCA in particular when performed delayed... - Physical training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogenesisUlrich Laufs
Medizinische Klinik und Poliklinik der Universität des Saarlandes, Innere Medizin III, Homburg, Germany
Circulation 109:220-6. 2004..Bone marrow-derived endothelial progenitor cells (EPCs) are thought to exert beneficial effects on atherosclerosis, angiogenesis, and vascular repair... - Beneficial association of ?-blocker therapy on recovery from severe acute heart failure treatment: data from the Survival of Patients With Acute Heart Failure in Need of Intravenous Inotropic Support trialMichael Bohm
Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
Crit Care Med 39:940-4. 2011..The aim is to determine whether ?-blocker use at study entry and/or at discharge has an impact on 31- and 180-day survival... - [Acute coronary syndrome--better risk stratification by determination of inflammatory parameters?]Andreas Link
Innere Medizin III Kardiologie Angiologie, Universitatskliniken des Saarlandes, Homburg Saar
Med Klin (Munich) 97:63-9. 2002.... - O,N,N'-trialkylisoureas as mild activating reagents for N-acylsulfonamide anchorsVida Zohrabi-Kalantari
, , Marbacher Weg 6, D-35032 Marburg, Germany
Org Lett 7:5665-7. 2005..Besides the demonstration of the feasibility of these mild alkylating agents for this purpose, custom-tailored novel O,N,N'-trialkylisoureas prepared from electron-deficient alcohols are reported... - N-acyl-N-alkyl-sulfonamide anchors derived from Kenner's safety-catch linker: powerful tools in bioorganic and medicinal chemistryPhilipp Heidler
Faculty of Pharmacy, Philipps-University Marburg, Marbacher Weg 6, D-35032, Germany
Bioorg Med Chem 13:585-99. 2005..Over the years this linker type emerged in several different chemical disciplines and nowadays it presents a useful and broadly applicable tool. Recent advancements and applications based on Kenner's safety-catch linker are reviewed... - Potential role of dendritic cells in atherogenesisAndreas Link
Cardiovasc Res 55:708-9. 2002