Research Topics
Genomes and GenesSpecies | Christian WegenerSummaryAffiliation: Philipps University Country: Germany Publications
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Publications
A large population of diverse neurons in the Drosophila central nervous system expresses short neuropeptide F, suggesting multiple distributed peptide functionsDick R Nassel
Department of Zoology, Stockholm University, S 10691 Stockholm, Sweden
BMC Neurosci 9:90. 2008..To unravel possible functional diversity we have mapped the distribution of transcript of the snpf gene and its peptide products in the central nervous system (CNS) of Drosophila in relation to other neuronal markers...- Molecular evolution of neuropeptides in the genus DrosophilaChristian Wegener
Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University, Karl von Frisch Strasse, D 35032 Marburg, Germany
Genome Biol 9:R131. 2008..The fully sequenced genomes of 12 Drosophila species provide a unique opportunity to study the molecular evolution of neuropeptides... - Deficiency of prohormone convertase dPC2 (AMONTILLADO) results in impaired production of bioactive neuropeptide hormones in DrosophilaChristian Wegener
Department of Biology, Animal Physiology, Philipps University, Marburg, Germany
J Neurochem 118:581-95. 2011..The lack of AMON activity resulted in a deficiency of L3 larva to enter the wandering phase. In conclusion, our findings provide the first direct evidence that AMON is a key enzyme in the production of neuropeptides in the fruitfly... - Neuroarchitecture of peptidergic systems in the larval ventral ganglion of Drosophila melanogasterJonathan G Santos
Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University, Marburg, Germany
PLoS ONE 2:e695. 2007..The data can further be useful to identify colocalized transmitters and receptors, and develop peptidergic neurons as new landmarks... - Direct peptide profiling of lateral cell groups of the antennal lobes of Manduca sexta reveals specific composition and changes in neuropeptide expression during developmentSandra Utz
Fachbereich Biologie, Tierphysiologie, Philipps Universitat, Marburg, Germany
Dev Neurobiol 67:764-77. 2007..The identification of neuropeptides in the antennal lobes now allows to specifically address the function of these signaling molecules during the formation of the antennal lobe network... - Neurotransmitter-induced changes in the intracellular calcium concentration suggest a differential central modulation of CCAP neuron subsets in DrosophilaMatthias Vömel
Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University Marburg, Karl von Frisch Strasse, Marburg D 35032, Germany
Dev Neurobiol 67:792-808. 2007..Our results suggest that N(CCAP) express functional receptors for ACh, glutamate, and GABA, and indicate that these transmitters are involved in a context-dependent regulation of functionally distinct N(CCAP) subsets... - Neuroarchitecture of aminergic systems in the larval ventral ganglion of Drosophila melanogasterMatthias Vömel
Emmy Noether Neuropeptide Group, Animal Physiology, Department of Biology, Philipps University Marburg, Marburg, Germany
PLoS ONE 3:e1848. 2008.... - Direct peptide profiling of brain tissue by MALDI-TOF mass spectrometryJoachim Schachtner
Department of Biology, Animal Physiology, Philipps University, Marburg, Germany
Methods Mol Biol 615:129-35. 2010..With this method, one can routinely and reliably obtain neuropeptide signatures of selected brain areas from various insects... - Peptidomics and peptide hormone processing in the Drosophila midgutWencke Reiher
Department of Biology, Animal Physiology, Philipps University Marburg, Marburg, Germany
J Proteome Res 10:1881-92. 2011..The identification of enteroendocrine peptides in the fruit fly provides a platform to address functions of gut peptide hormones in the regulation of feeding and metabolism... - Direct MALDI-TOF mass spectrometric peptide profiling of neuroendocrine tissue of DrosophilaChristian Wegener
Emmy Noether Neuropeptide Group, Animal Physiology, Philipps University, Marburg, Germany
Methods Mol Biol 615:117-27. 2010..Here, we describe protocols for the use of MALDI-TOF mass spectrometry to directly analyze the peptidome of neuroendocrine tissues of insects, particularly Drosophila melanogaster, by MALDI-TOF MS... - A simple purification protocol for the detection of peptide hormones in the hemolymph of individual insects by matrix-assisted laser desorption/ionization time-of-flight mass spectrometrySandy Fastner
Emmy Noether Neuropeptidgruppe, FB Biologie, Tierphysiologie, Philipps Universitat, Karl von Frisch Strasse, D 35032 Marburg, Germany
Rapid Commun Mass Spectrom 21:23-8. 2007..Since this method is simple, relatively cheap and fast, it should be useful for routine endocrinological analyses and for monitoring peptide release during different physiological conditions and behaviors in insects... - Morphology and metamorphosis of the peptidergic Va neurons and the median nerve system of the fruit fly, Drosophila melanogasterJonathan G Santos
Emmy Noether Neuropeptide Group, Department of Biology, Animal Physiology, Philipps University, Karl-von-Frisch-Strasse, 35032, Marburg, Germany
Cell Tissue Res 326:187-99. 2006..Hence, the transverse nerves may serve a neurohaemal function in D. melanogaster...