Research Topics
Genomes and Genes | B KadenbachSummaryAffiliation: Philipps University Country: Germany Publications
| Collaborators
|
Detail Information
Publications
The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseasesBernhard Kadenbach
Fachbereich Chemie, Philipps Universitat, Hans Meerwein Strasse, D 35032 Marburg, Germany
Biochim Biophys Acta 1655:400-8. 2004..Consequently, energy metabolism changes to an excited state. We propose that this change causes an increase in DeltaPsi(m), a condition for the formation of ROS and induction of apoptosis...- Intrinsic and extrinsic uncoupling of oxidative phosphorylationBernhard Kadenbach
Fachbereich Chemie, Philipps Universitat, Hans Meerwein Strasse, D 35032 Marburg, Germany
Biochim Biophys Acta 1604:77-94. 2003..Finally, the regulation of DeltaPsi and the production of reactive oxygen species (ROS) in mitochondria at high DeltaPsi values (150-200 mV) are discussed... - Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidaseB Kadenbach
Fachbereich Chemie, Philipps Universitat, Marburg, Germany
Free Radic Biol Med 29:211-21. 2000..High substrate pressure (sigmoidal v/s kinetics), palmitate and 3,5-diiodothyronine (binding to subunit Va) increase also delta p, ROS production and slip but without dephosphorylation of COX... - A second mechanism of respiratory controlB Kadenbach
Fachbereich Chemie, Philipps Universitat, Marburg, Germany
FEBS Lett 447:131-4. 1999.... - Turkey cytochrome c oxidase contains subunit VIa of the liver type associated with low efficiency of energy transductionM Huttemann
Fachbereich Chemie, Philipps Universitat, Marburg, Germany
Eur J Biochem 267:2098-104. 2000..85 at low and 0.48 at high intraliposomal ATP/ADP ratios. The results suggest that in birds the lower H+/e-ratio of cytochrome c oxidase participates in elevated resting metabolic rate and thermogenesis... - New control of mitochondrial membrane potential and ROS formation--a hypothesisI Lee
Fachbereich Chemie, , Marburg, Germany
Biol Chem 382:1629-36. 2001..We propose that 'stress hormones' which increase intracellular [Ca2+] also increase delta(psi)m and ROS formation, which promote degenerative diseases and accelerate aging... - Palmitate decreases proton pumping of liver-type cytochrome c oxidaseI Lee
Fachbereich Chemie, , D-35032 Marburg, Germany
Eur J Biochem 268:6329-34. 2001..0 to 0.5 by 5 mm intraliposomal ATP (instead of 5 mm ADP). It is assumed that palmitate binds to subunit VIaL. The partial uncoupling of proton pumping in cytochrome c oxidase is suggested to participate in mammalian thermogenesis... - Structural organisation of the rat genes encoding liver- and heart-type of cytochrome c oxidase subunit VIa and a pseudogene related to the COXVIa-L cDNAO C Mell
Fachbereich Chemie, Philipps Universitat, Marburg, Germany
Gene 140:179-86. 1994..In addition, we have analyzed a pseudogene, showing 84% homology to the COXVIa-L cDNA sequence... - Isolation and sequence of the human cytochrome c oxidase subunit VIIaL geneM Huttemann
Fachbereich Chemie, Philipps Universitat, D35032 Marburg, Germany
Biochim Biophys Acta 1492:252-8. 2000..A surprising transcription of COX7AH was observed in cultured fibroblasts, suggesting a potential utility of these cells for study of its gene expression... - The cDNA sequences of cytochrome c oxidase subunit VIa from carp and rainbow trout suggest the absence of isoforms in fishesM Huttemann
Fachbereich Chemie, Philipps Universitat, Marburg, Germany
Biochim Biophys Acta 1319:14-8. 1997..and Kadenbach, B. (1996) FEBS Lett. 382, 121-124), is absent... - Biochemical analysis of fibroblasts from patients with cytochrome c oxidase-associated Leigh syndromeS Possekel
Fachbereich Chemie, Philipps Universitat, Marburg, Germany
Biochim Biophys Acta 1316:153-9. 1996..The results indicate a defective COX holoenzyme complex in patients with Leigh syndrome and suggest different molecular origins of the defect... - Complexity of nucleus-encoded genes of mammalian cytochrome c oxidaseX N Cao
Biochemie, Fachbereich Chemie, , Marburg, Federal Republic of Germany
Ann N Y Acad Sci 550:337-47. 1988 - Nucleotide sequence of cDNA encoding subunit VIII of cytochrome c oxidase from rat heartK Scheja
Fachbereich Chemie, Philipps Universitat, Marburg, Germany
Biochim Biophys Acta 1132:91-3. 1992..A rat skeletal muscle cDNA library was screened with a 132 bp fragment of the cDNA of rat COX subunit VIII-h. Four positive clones were sequenced in both directions... - Nucleotide sequence of cDNA encoding subunit IV of cytochrome c oxidase from fetal rat liverG Gopalan
Fachbereich Chemie, , Marburg, FRG
Nucleic Acids Res 17:4376. 1989 - Different isozymes of cytochrome c oxidase are expressed in bovine smooth muscle and skeletal or heart muscleG Anthony
Fachbereich Chemie der Philipps Universität, Marburg, Germany
FEBS Lett 277:97-100. 1990..SDS-PAGE as well as N-terminal amino acid sequencing of separated subunits from gel bands revealed the expression of the liver isoforms for subunits VIa and VIII and of the heart isoform for subunits VIIa in COX from smooth muscle... - Control of mitochondrial membrane potential and ROS formation by reversible phosphorylation of cytochrome c oxidaseIcksoo Lee
Fachereich Chemie, Philipps-University, Marburg, Germany
Mol Cell Biochem 234:63-70. 2002.... - Phosphorylation and kinetics of mammalian cytochrome c oxidaseStefan Helling
Medizinisches Proteom Center, Funktionelle Proteomik, Ruhr Universitat Bochum, Germany
Mol Cell Proteomics 7:1714-24. 2008....