Jens Minnerup

Summary

Country: Germany

Publications

  1. ncbi Continuous positive airway pressure ventilation for acute ischemic stroke: a randomized feasibility study
    Jens Minnerup
    Department of Neurology, University of Munster, Albert Schweitzer Straße 33, 48149 Munster, Germany
    Stroke 43:1137-9. 2012
  2. ncbi Intracarotid administration of human bone marrow mononuclear cells in rat photothrombotic ischemia
    Jens Minnerup
    Department of Neurology, , Albert Schweitzer Strasse 33, , Germany
    Exp Transl Stroke Med 2:3. 2010
  3. ncbi Erythropoietin for stroke treatment: dead or alive?
    Jens Minnerup
    Department of Neurology, University Hospital Munster, Albert Schweitzer Straße 33, 48149 Munster, Germany
    Crit Care 15:129. 2011
  4. ncbi The impact of lesion location and lesion size on poststroke infection frequency
    Jens Minnerup
    Department of Neurology, University of Munster, Munster, Germany
    J Neurol Neurosurg Psychiatry 81:198-202. 2010
  5. ncbi When percutaneous dilation tracheotomy may be hazardous: abnormal course of the brachiocephalic trunk
    Jens Minnerup
    Department of Neurology, University Hospital of Munster, Albert Schweitzer Str 33, D 48129, Muenster, Germany
    Neurocrit Care 10:336-8. 2009
  6. ncbi Effects of neural progenitor cells on sensorimotor recovery and endogenous repair mechanisms after photothrombotic stroke
    Jens Minnerup
    Universitatsklinikum Munster, Department of Neurology, Klinik und Poliklinik fur Neurologie, Albert Schweitzer Straße 33, 48149 Munster, Germany
    Stroke 42:1757-63. 2011
  7. ncbi Meta-analysis of the efficacy of granulocyte-colony stimulating factor in animal models of focal cerebral ischemia
    Jens Minnerup
    Universitatsklinikum Munster, Klinik und Poliklinik fur Neurologie, Albert Schweitzer Strasse 33, 48149 Munster, Germany
    Stroke 39:1855-61. 2008
  8. ncbi Methodological quality of preclinical stroke studies is not required for publication in high-impact journals
    Jens Minnerup
    Department of Neurology, University of Munster, Munster, Germany
    J Cereb Blood Flow Metab 30:1619-24. 2010
  9. ncbi The efficacy of erythropoietin and its analogues in animal stroke models: a meta-analysis
    Jens Minnerup
    Department of Neurology, University of Munster, Germany
    Stroke 40:3113-20. 2009
  10. ncbi Investigation of neuronal progenitor cell origin after transient focal cerebral ischemia in mice
    Jan Kolja Strecker
    Department of Neurology, University Hospital Munster, D 48129 Munster, Germany
    Neurosci Res 68:256-9. 2010

Detail Information

Publications23

  1. ncbi Continuous positive airway pressure ventilation for acute ischemic stroke: a randomized feasibility study
    Jens Minnerup
    Department of Neurology, University of Munster, Albert Schweitzer Straße 33, 48149 Munster, Germany
    Stroke 43:1137-9. 2012
    ..Sleep-related breathing disorders occur frequently after stroke. We assessed the feasibility of continuous positive airway pressure (CPAP) treatment initiated in the first night after stroke...
  2. ncbi Intracarotid administration of human bone marrow mononuclear cells in rat photothrombotic ischemia
    Jens Minnerup
    Department of Neurology, , Albert Schweitzer Strasse 33, , Germany
    Exp Transl Stroke Med 2:3. 2010
    ..A possible reason for the failed neurological improvement after cell therapy might be the delayed treatment initiation compared to other experimental stroke studies that showed efficacy of bone marrow mononuclear cells...
  3. ncbi Erythropoietin for stroke treatment: dead or alive?
    Jens Minnerup
    Department of Neurology, University Hospital Munster, Albert Schweitzer Straße 33, 48149 Munster, Germany
    Crit Care 15:129. 2011
    ..Although beneficial effects of EPO were observed, several issues regarding EPO's suitability as a stroke drug remain...
  4. ncbi The impact of lesion location and lesion size on poststroke infection frequency
    Jens Minnerup
    Department of Neurology, University of Munster, Munster, Germany
    J Neurol Neurosurg Psychiatry 81:198-202. 2010
    ..The authors investigated whether stroke location and stroke size are independent risk factors for poststroke infections...
  5. ncbi When percutaneous dilation tracheotomy may be hazardous: abnormal course of the brachiocephalic trunk
    Jens Minnerup
    Department of Neurology, University Hospital of Munster, Albert Schweitzer Str 33, D 48129, Muenster, Germany
    Neurocrit Care 10:336-8. 2009
    ..In contrast to the surgical approach, PDT involves a blind puncture and dilation of the pretracheal space, which may predispose to dangerous complications in the case of anatomical, in particular vascular, anomalies...
  6. ncbi Effects of neural progenitor cells on sensorimotor recovery and endogenous repair mechanisms after photothrombotic stroke
    Jens Minnerup
    Universitatsklinikum Munster, Department of Neurology, Klinik und Poliklinik fur Neurologie, Albert Schweitzer Straße 33, 48149 Munster, Germany
    Stroke 42:1757-63. 2011
    ..The underlying mechanisms, however, are not completely understood so far. Here, we investigated the effects of systemic NPC transplantation on endogenous neurogenesis and dendritic plasticity of host neurons...
  7. ncbi Meta-analysis of the efficacy of granulocyte-colony stimulating factor in animal models of focal cerebral ischemia
    Jens Minnerup
    Universitatsklinikum Munster, Klinik und Poliklinik fur Neurologie, Albert Schweitzer Strasse 33, 48149 Munster, Germany
    Stroke 39:1855-61. 2008
    ..To guide further development, a meta-analysis was performed to assess the effects of G-CSF on infarct size and sensorimotor deficits...
  8. ncbi Methodological quality of preclinical stroke studies is not required for publication in high-impact journals
    Jens Minnerup
    Department of Neurology, University of Munster, Munster, Germany
    J Cereb Blood Flow Metab 30:1619-24. 2010
    ..The major predictor for accepting preclinical stroke studies in high-impact journals is the complexity of the investigation into a stroke drug's mode of action...
  9. ncbi The efficacy of erythropoietin and its analogues in animal stroke models: a meta-analysis
    Jens Minnerup
    Department of Neurology, University of Munster, Germany
    Stroke 40:3113-20. 2009
    ..We performed a meta-analysis to obtain an overall impression of the efficacy of EPO in published animal experimental stroke studies and for potential guidance of future clinical studies...
  10. ncbi Investigation of neuronal progenitor cell origin after transient focal cerebral ischemia in mice
    Jan Kolja Strecker
    Department of Neurology, University Hospital Munster, D 48129 Munster, Germany
    Neurosci Res 68:256-9. 2010
    ..In our experiments we found no blood-borne neuronal precursors within the ischemic site indicating that detected neuronal progenitor cells are only of brain parenchymal origin...
  11. ncbi Prediction of malignant middle cerebral artery infarction using computed tomography-based intracranial volume reserve measurements
    Jens Minnerup
    Department of Clinical Radiology, University of Munster, Albert Schweitzer Straße 33, 48149 Munster, Germany or Jens Minnerup, MD, Department of Neurology, University of Munster, Albert Schweitzer Straße 33, 48149 Munster, Germany e mail
    Stroke 42:3403-9. 2011
    ..However, CSF volume was not investigated as a predictor of malignant infarction so far. We hypothesize that assessment of CSF volume in addition to admission infarct size improves early prediction of malignant MCA infarction...
  12. ncbi Successful regeneration after experimental stroke by granulocyte-colony stimulating factor is not further enhanced by constraint-induced movement therapy either in concurrent or in sequential combination therapy
    Kai Diederich
    Department of Neurology, University of Munster, Munster, Germany
    Stroke 43:185-92. 2012
    ....
  13. ncbi Effects of granulocyte-colony stimulating factor after stroke in aged rats
    Aurel Popa-Wagner
    Department of Neurology, University of Greifswald, Greifswald, Germany
    Stroke 41:1027-31. 2010
    ..We tested the hypothesis that G-CSF provides a restorative therapeutic benefit in aged animals...
  14. ncbi Multifunctional actions of approved and candidate stroke drugs
    Jens Minnerup
    Department of Neurology, University of Munster, Albert Schweitzer Strasse 33, 48149 Munster, Germany
    Neurotherapeutics 6:43-52. 2009
    ..These drugs offer hope that additional treatment options for the acute phase after a stroke will become available in the near future...
  15. ncbi Impact of the extended thrombolysis time window on the proportion of recombinant tissue-type plasminogen activator-treated stroke patients and on door-to-needle time
    Jens Minnerup
    Department of Neurology, Institute of Epidemiology and Social Medicine, University of Munster, Domagkstrasse 3, Munster, Germany
    Stroke 42:2838-43. 2011
    ..We investigated the effect of the extended thrombolysis time window on the proportion of recombinant tissue-type plasminogen activator-treated stroke patients and on the time of treatment initiation after hospital arrival...
  16. ncbi Semaphorin 6A improves functional recovery in conjunction with motor training after cerebral ischemia
    Andreas Rogalewski
    Department of Neurology, University of Muenster, Muenster, Germany
    PLoS ONE 5:e10737. 2010
    ..We conclude that semaphorin 6a overexpressed in the cortex enhances recovery after cerebral ischemia. Semaphorin 6a may represent a novel therapeutic candidate for the treatment of chronic stroke...
  17. ncbi Monocyte chemoattractant protein-1-deficiency impairs the expression of IL-6, IL-1? and G-CSF after transient focal ischemia in mice
    Jan Kolja Strecker
    Department of Neurology, University of Munster, Munster, Germany
    PLoS ONE 6:e25863. 2011
    ..These novel results help to understand post ischemic, inflammatory mechanisms and might give further arguments towards therapeutical interventions by modulation of MCP-1 expression in post stroke inflammation...
  18. ncbi Case report of MR perfusion imaging in sinking skin flap syndrome: growing evidence for hemodynamic impairment
    Andre Kemmling
    Institute for Clinical Radiology, University Hospital of Muenster, Albert Schweitzer Strasse 33, 48149 Muenster, Germany
    BMC Neurol 10:80. 2010
    ..We report a case of sinking skin flap syndrome (SSFS) with recovery from neurological sensorimotor deficits after cranioplasty correlated with pre- and postsurgical MR brain perfusion studies...
  19. ncbi MCP-1/CCR-2-double-deficiency severely impairs the migration of hematogenous inflammatory cells following transient cerebral ischemia in mice
    Katharina Schuette-Nuetgen
    Department of Neurology, University of Munster, Albert Schweitzer Str 33, 48129 Munster, Germany
    Exp Neurol 233:849-58. 2012
    ..Further studies are needed to clarify whether these mechanisms of inflammatory cell recruitment might be essential for early infarct development and final infarct size and to evaluate potential therapeutic implications...
  20. ncbi Severe leukoencephalopathy with fulminant cerebral edema reflecting immune reconstitution inflammatory syndrome during HIV infection: a case report
    Christian Oelschlaeger
    University Hospital Muenster, Department of Neurology, A, Schweitzer Str, 33, D 48129 Muenster, Germany
    J Med Case Reports 4:214. 2010
    ..Generally, immune reconstitution inflammatory syndrome is based on opportunistic infections, but rare cases of immune reconstitution inflammatory syndrome inducing demyelinization of the nervous system have also been observed...
  21. ncbi Seeing old friends from a different angle: Novel properties of hematopoietic growth factors in the healthy and diseased brain
    Kai Diederich
    Department of Neurology, University of Munster, Munster, Germany
    Hippocampus 22:1051-7. 2012
    ..2010 Wiley Periodicals, Inc...
  22. ncbi The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice
    Kai Diederich
    Department of Neurology, University of Muenster, 48149 Muenster, Germany
    J Neurosci 29:11572-81. 2009
    ....
  23. ncbi Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin
    Liliana Schaefer
    Departments of Internal Medicine D, University of Munster, Munster, Germany
    Am J Pathol 170:301-15. 2007
    ..This study provides evidence for the involvement of decorin and the IGF-I receptor/mTOR/p70 S6 kinase signaling pathway in the translational regulation of fibrillin-1...