Christiane Nüsslein-Volhard

Summary

Affiliation: Max Planck Institute for Biological Cybernetics
Country: Germany

Publications

  1. Migration and function of a glial subtype in the vertebrate peripheral nervous system
    Darren T Gilmour
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tübingen, Germany
    Neuron 34:577-88
  2. Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo
    Iphigenie Charatsi
    Abteilung Genetik, Max Planck Institut für Entwicklungsbiologie, Spemannstrasse 35, 72076 Tubingen, Germany
    Mech Dev 120:219-26
  3. An evolutionary conserved region in the vasa 3'UTR targets RNA translation to the germ cells in the zebrafish
    Holger Knaut
    Abteilung III Genetik, Max Planck Institut für Entwicklungsbiologie, Tübingen, Germany
    Curr Biol 12:454-66
  4. Large-scale mapping of mutations affecting zebrafish development
    Robert Geisler
    Department 3 Genetics, Max Planck Institut für Entwicklungsbiologie, Spemannstr, 35 III, 72076 Tübingen, Germany
    BMC Genomics 8:11
  5. The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline
    Nina Vogt
    Max Planck Institute for Developmental Biology, Department of Genetics, Spemannstr 35, 72076 Tübingen, Germany
    Development 133:3963-72
  6. Retroactive, a membrane-anchored extracellular protein related to vertebrate snake neurotoxin-like proteins, is required for cuticle organization in the larva of Drosophila melanogaster
    Bernard Moussian
    Department of Genetics, Max Planck Institute for Developmental Biology, Tübingen, Germany
    Dev Dyn 233:1056-63
  7. Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster
    Bernard Moussian
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, D 72076 Tübingen, Germany
    J Morphol 264:117-30
  8. Towing of sensory axons by their migrating target cells in vivo
    Darren Gilmour
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tuebingen, Germany
    Nat Neurosci 7:491-2
  9. The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote
    Marcus P S Dekens
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tübingen, Germany
    Development 130:3907-16
  10. Formation of the adult pigment pattern in zebrafish requires leopard and obelix dependent cell interactions
    Florian Maderspacher
    Max Planck Institut für Entwicklungsbiologie, Abt III Genetik, Spemannstrasse 35, 72076 Tübingen, Germany
    Development 130:3447-57

Collaborators

Detail Information

Publications17

  1. Migration and function of a glial subtype in the vertebrate peripheral nervous system
    Darren T Gilmour
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tübingen, Germany
    Neuron 34:577-88
    ..Furthermore, mutations in the transcription factor Sox10/cls uncouple the migration of axons and glia. Finally, genetic ablation of this glial subtype reveals an essential role in nerve fasciculation...
  2. Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo
    Iphigenie Charatsi
    Abteilung Genetik, Max Planck Institut für Entwicklungsbiologie, Spemannstrasse 35, 72076 Tubingen, Germany
    Mech Dev 120:219-26
    ..Tube in turn interacts with its downstream effector Pelle through death domain association. We therefore suggest that upon Toll activation, Kra associates with Pelle and Tube, in an heterotrimeric complex...
  3. An evolutionary conserved region in the vasa 3'UTR targets RNA translation to the germ cells in the zebrafish
    Holger Knaut
    Abteilung III Genetik, Max Planck Institut für Entwicklungsbiologie, Tübingen, Germany
    Curr Biol 12:454-66
    ..CONCLUSIONS: Our results suggest the existence of a common RNA localization machinery in lower vertebrates that uses a functionally conserved localization signal to target gene expression to the germline...
  4. Large-scale mapping of mutations affecting zebrafish development
    Robert Geisler
    Department 3 Genetics, Max Planck Institut für Entwicklungsbiologie, Spemannstr, 35 III, 72076 Tübingen, Germany
    BMC Genomics 8:11
    ..Furthermore this work validates the usefulness of our methodology for rapid, systematic and inexpensive microsatellite mapping of zebrafish mutations...
  5. The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline
    Nina Vogt
    Max Planck Institute for Developmental Biology, Department of Genetics, Spemannstr 35, 72076 Tübingen, Germany
    Development 133:3963-72
    ..The gammaTuRC cap structure may be essential only for non-centrosome-based microtubule functions...
  6. Retroactive, a membrane-anchored extracellular protein related to vertebrate snake neurotoxin-like proteins, is required for cuticle organization in the larva of Drosophila melanogaster
    Bernard Moussian
    Department of Genetics, Max Planck Institute for Developmental Biology, Tübingen, Germany
    Dev Dyn 233:1056-63
    ..We propose that this binding function of Rtv may assist the organization of chitin fibers at the epidermal cell surface during cuticle assembly...
  7. Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster
    Bernard Moussian
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, D 72076 Tübingen, Germany
    J Morphol 264:117-30
    ....
  8. Towing of sensory axons by their migrating target cells in vivo
    Darren Gilmour
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tuebingen, Germany
    Nat Neurosci 7:491-2
    ..Here we combine genetics and time-lapse imaging in the zebrafish to show that towing by migrating cells is a bona fide mechanism for guiding pathfinding axons in vivo...
  9. The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote
    Marcus P S Dekens
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tübingen, Germany
    Development 130:3907-16
    ..Therefore, we propose that in mitotic spindle assembly chromosome-dependent microtubule nucleation is essential for the coupling of nuclear and cell division...
  10. Formation of the adult pigment pattern in zebrafish requires leopard and obelix dependent cell interactions
    Florian Maderspacher
    Max Planck Institut für Entwicklungsbiologie, Abt III Genetik, Spemannstrasse 35, 72076 Tübingen, Germany
    Development 130:3447-57
    ..These findings support a view in which cell-cell interactions among pigment cells are the major driving force for adult pigment pattern formation...
  11. A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor
    Holger Knaut
    Max Planck Institut für Entwicklungsbiologie, Abteilung III Genetik, Spemannstrasse 35, 72076 Tübingen, Germany
    Nature 421:279-82
    ....
  12. Gamma-tubulin37C and gamma-tubulin ring complex protein 75 are essential for bicoid RNA localization during drosophila oogenesis
    Frank Schnorrer
    Max Planck Institut für Entwicklungsbiologie, Abteilung Genetik, Spemannstr 35, 72076, Tübingen, Germany
    Dev Cell 3:685-96
    ..At stage 10b, we find gammaTub37C and Dgrip75 anteriorly concentrated and propose the formation of a microtubule-organizing center at the anterior pole of the oocyte...
  13. Zebrafish eda and edar mutants reveal conserved and ancestral roles of ectodysplasin signaling in vertebrates
    Matthew P Harris
    Max Planck Institute for Developmental Biology, Tübingen, Germany
    PLoS Genet 4:e1000206
    ..Lastly, our findings point to the utility of adult genetic screens in the zebrafish in identifying essential developmental processes involved in human disease and in morphological evolution...
  14. Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo
    Francesca Peri
    Max Planck Institute for Developmental Biology, Spemannstr 35, 72076 Tübingen, Germany
    Cell 133:916-27
    ..As a real-time description of microglial phagocytosis in vivo, this work advances our understanding of microglial-mediated neuronal degeneration, a hallmark of many neuronal diseases...