Research Topics
| Christine NorraSummaryAffiliation: Max Planck Institute for Experimental Medicine Country: Germany Publications
| Collaborators
|
Detail Information
Publications
Challenge tests of monoaminergic systems: neurophysiological aspectsChristine Norra
From the Max Planck lnstitute for Experimental Medicine, Division of Clinical Neuroscience, Gottingen, Germany
Clin EEG Neurosci 38:66-73. 2007..This article focuses on electrophysiological methodology and results of monoamine depletion studies (i.e., electroencephalography, magnetoencephalography, polysomnography, auditory evoked potentials and startle response)...
Effects of experimental acute tryptophan depletion on acoustic startle response in femalesChristine Norra
Department of Psychiatry and Psychotherapy, University Hospital RWTH, Aachen, Germany
Eur Arch Psychiatry Clin Neurosci 258:1-9. 2008..In conclusion, this first study of startle parameters after TDT in a homogenous female population demonstrates that depletion of brain 5-HT in women only influences ASR...
Loudness dependence of evoked dipole source activity during acute serotonin challenge in femalesChristine Norra
Department of Psychiatry and Psychotherapy, Aachen University Hospital, Aachen, Germany
Hum Psychopharmacol 23:31-42. 2008..Gender must be taken into particular account here, since there are gender differences in 5-HT brain synthesis, with women reacting more strongly to TDT...
High impact of depression in heart failure: early diagnosis and treatment optionsChristine Norra
Department of Psychiatry and Psychotherapy, University Hospital, Aachen, Germany
Int J Cardiol 125:220-31. 2008..Recommendations are made for treating depression in CHF patients for a better prevention of this disabling physical and psychosocial condition...
Enhanced intensity dependence as a marker of low serotonergic neurotransmission in borderline personality disorderChristine Norra
Department of Psychiatry and Psychotherapy, Medical Faculty of the University of Technology RWTH Aachen, Pauwelstrasse 30, D 52074 Aachen, Germany
J Psychiatr Res 37:23-33. 2003..Our findings contribute a further argument to the hypothesis of low serotonergic neurotransmission in BDP and may point to a trait character of impulsiveness in this personality disorder...
Mismatch negativity generation in the human 5HT2A agonist and NMDA antagonist model of psychosisKarsten Heekeren
Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924, Cologne, Germany
Psychopharmacology (Berl) 199:77-88. 2008..Previous studies reported a significant reduction of MMN after ketamine (N-methyl-D-aspartate acid [NMDA] antagonist model) but not after psilocybin (5HT2A agonist model)...
Electrophysiological evidence for altered early cerebral somatosensory signal processing in schizophreniaTill D Waberski
Department of Neurology, University Hospital Aachen, Aachen, Germany
Psychophysiology 41:361-6. 2004..In the low-frequency part of the SEPs an increase in amplitude was found. These results are interpreted to reflect a lack of somatosensory inhibition in the somatosensory pathway, either at a thalamic or a cortical level...
Sensitivity and specificity of the Beck Depression Inventory in cardiologic inpatients: how useful is the conventional cut-off score?Thomas Forkmann
Institute of Medical Psychology and Medical Sociology, University Hospital of RWTH Aachen, Aachen, Germany
J Psychosom Res 67:347-52. 2009....
Psychometric evaluation of the Rasch-based depression screening in patients with neurologic disordersThomas Forkmann
Institute of Medical Psychology and Medical Sociology, University Hospital of Rheinisch Westfälische Technische Hochschule, Aachen, Germany
Arch Phys Med Rehabil 91:1188-93. 2010..To provide a first evaluation of the Rasch-Based Depression Screening (DESC) in consecutive patients with neurologic disorders...
High-frequency somatosensory thalamocortical oscillations and psychopathology in schizophreniaChristine Norra
Department of Psychiatry and Psychotherapy, Aachen University, Aachen, Germany
Neuropsychobiology 49:71-80. 2004....
Impact of sleep-related breathing disorders on health-related quality of life in patients with chronic heart failureErik Skobel
Department of Cardiology and Pulmonary Disease, RWTH University Hospital, Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
Eur J Heart Fail 7:505-11. 2005....
Early sensory encoding of affective prosody: neuromagnetic tomography of emotional category changesHeike Thönnessen
Department of Psychiatry and Psychotherapy, JARA Translational Brain Medicine, RWTH Aachen University, Germany
Neuroimage 50:250-9. 2010..Processing of cognitive feature extraction and automatic emotion appraisal may overlap at this level enabling rapid attentional shifts to important social cues...
Development and validation of the Rasch-based Depression Screening (DESC) using Rasch analysis and structural equation modellingThomas Forkmann
Institute of Medical Psychology and Medical Sociology, University Hospital of the RWTH Aachen University, Aachen, Germany
J Behav Ther Exp Psychiatry 40:468-78. 2009..Cut-off scores with good sensitivity and specificity were developed using ROC analyses. Results suggest that DESC may be appropriately used to screen for depression and may be beneficial for repeated measurements...
Theories of delusional disorders. An update and reviewHanns Jurgen Kunert
Max Planck Institute for Experimental Medicine, Gottingen, Germany
Psychopathology 40:191-202. 2007..The aim of this paper is to provide a comprehensive review and critical assessment of the various, rather heterogeneous theories in this field...
Exploring recombinant human erythropoietin in chronic progressive multiple sclerosisHannelore Ehrenreich
Division of Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Georg August University, Gottingen, Germany
Brain 130:2577-88. 2007..There were no adverse events, no safety concerns and a surprisingly low need of blood-lettings. This first pilot study demonstrates the necessity and feasibility of controlled trials using high-dose rhEPO in chronic progressive MS...
Mood disorders and their treatment in patients with epilepsyChristian Prueter
Department of Psychiatry and Psychotherapy of the Technical University, Neuropsychiatric Research Group, University Hospital, Pauwelsstrasse 30, 52074 Aachen, Germany
J Neuropsychiatry Clin Neurosci 17:20-8. 2005..Despite an insufficient number of available controlled studies, based on the current data, treatment with the newer serotonergic antidepressants can be recommended for patients with epilepsy...
Cardiac resynchronization therapy improves central sleep apnea and Cheyne-Stokes respiration in patients with chronic heart failureAnil-Martin Sinha
Department of Cardiology, University Hospital, RWTH, Aachen, Germany
J Am Coll Cardiol 44:68-71. 2004..CONCLUSIONS: Cardiac resynchronization therapy leads to a reduction of CSA and to increased sleep quality in patients with HF and sleep-related breathing disorders. This may have prognostic implications in patients receiving CRT...
Palinacousis leading to the diagnosis of temporal lobe seizures in a patient with schizophreniaChristian Prueter
Department of Psychiatry and Psychotherapy, Medical Faculty of the University of Technology RWTH, University Hospital, Pauwelsstrasse 30, 52074 Aachen, Germany
Seizure 11:198-200. 2002..Repeated EEG recordings showed a left temporal theta focus with spikes. The diagnosis of temporal lobe seizures was made. Treatment with carbamazepine led to complete recovery...
Prediction of clinical response to antidepressants in patients with depression: neurophysiology in clinical practiceOliver Pogarell
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Clin EEG Neurosci 38:74-7. 2007..This review focuses on recent studies providing evidence for the validity of LD as an indirect serotonergic marker and highlights data on the clinical application in terms of prediction of treatment response in patients with depression...
Comparative source localization of electrically and pressure-stimulated multichannel somatosensory evoked potentialsWolfram Kawohl
Psychiatric University Hospital, Zurich, Switzerland
J Clin Neurophysiol 24:257-62. 2007..For cortical plasticity studies, peripheral somatosensory stimulation is of great importance. According to these findings, the choice of method, electrical or mechanical stimulation, may depend on practical criteria...
