Research Topics
Species | E KalbeSummaryAffiliation: Max-Planck-Institute for Neurological Research Country: Germany Publications
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Detail Information
Publications
[Number processing and acalculia in dementia]E Kalbe
Max Planck Institut für neurologische Forschung Gleueler Str 50 50931 Köln, Germany
Z Gerontol Geriatr 35:88-101. 2002....- A new test battery to assess aphasic disturbances and associated cognitive dysfunctions -- German normative data on the aphasia check listElke Kalbe
Max Planck Institute for Neurological Research, Cologne, Germany
J Clin Exp Neuropsychol 27:779-94. 2005..The ACL cognition part revealed additional neuropsychological dysfunction in the aphasia group. We present the patterns of these dysfunctions and their correlations with language deficits... - The Rapid Dementia Screening Test (RDST): a new economical tool for detecting possible patients with dementiaElke Kalbe
Max Planck Institute for Neurological Research, Cologne, Germany
Dement Geriatr Cogn Disord 16:193-9. 2003..The RDST is thus an economical tool for detecting demented patients by general practitioners... - Anosognosia in very mild Alzheimer's disease but not in mild cognitive impairmentE Kalbe
Department of Neurology, University Hospital, and Max Planck Institute for Neurological Research, Cologne, Germany
Dement Geriatr Cogn Disord 19:349-56. 2005..To study awareness of cognitive dysfunction in patients with very mild Alzheimer's disease (AD) and subjects with mild cognitive impairment (MCI)... - DemTect: a new, sensitive cognitive screening test to support the diagnosis of mild cognitive impairment and early dementiaE Kalbe
Max Planck Institute for Neurological Research, Cologne, Germany
Int J Geriatr Psychiatry 19:136-43. 2004..To design a new, highly sensitive psychometric screening to identify patients with mild cognitive impairment (MCI) and patients with dementia in the early stages of the disease... - Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivoJ C Klein
Department of Neurology, Goethe University, Frankfurt am Main, Germany
Neurology 74:885-92. 2010..Whether both are distinct disease entities is an ongoing controversy. Therefore, we directly compared patients with DLB and PDD with multitracer PET... - Frontal FDG-PET activity correlates with cognitive outcome after STN-DBS in Parkinson diseaseE Kalbe
Department of Neurology, University of Cologne, Germany
Neurology 72:42-9. 2009..To investigate the underlying pathomechanisms, we correlated alterations of cognitive test performance and changes of neuronal energy metabolism in frontal basal ganglia projection areas under bilateral STN stimulation... - Learning face-name associations and the effect of age and performance: a PET activation studyK Herholz
Max Planck Institut für neurologische Forschung and Neurologische Universitätsklinik, Gleuler Str 50, D 50931, Cologne, Germany
Neuropsychologia 39:643-50. 2001..Learning is further mediated by a predominantly left-hemispheric network including inferior temporal and orbitofrontal cortex... - CSF total and phosphorylated tau protein, regional glucose metabolism and dementia severity in Alzheimer's diseaseC Haense
Max Planck Institute for Neurological Research, Cologne, Germany
Eur J Neurol 15:1155-62. 2008.... - Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathwaysR Hilker
Department of Neurology, University of Cologne, Cologne, Germany
Neurology 65:1716-22. 2005..To assess neurochemical deficits in patients with Parkinson disease (PD) associated dementia (PDD) in vivo... - Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her childrenE Kalbe
Department of Neurology, University Clinic Cologne, Cologne, Germany
Neurocase 14:15-28. 2008..Furthermore, they indicate that beliefs or prejudices may have a major impact on the brain's processing of the personal past... - Elevated emotional reactivity in affective but not cognitive components of theory of mind: a psychophysiological studyE Kalbe
Department of Neurology, University of Cologne, Germany
J Neuropsychol 1:27-38. 2007..We discuss the possible underlying mechanisms for these differential psychophysiological correlates of affective and cognitive ToM processing, and suggest further investigations especially in clinical populations... - Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PETK Herholz
University Cologne, Neurological Clinic and Max Planck Institute for Neurological Research, 50931 Koln, Germany
Neuroimage 17:302-16. 2002..Ventromedial frontal cortex was also abnormal. In conclusion, automated analysis of multicenter FDG PET is feasible, provides insights into AD pathophysiology, and can be used potentially as a sensitive biomarker for early AD diagnosis... - In vivo study of acetylcholine esterase in basal forebrain, amygdala, and cortex in mild to moderate Alzheimer diseaseK Herholz
Department of Neurology, University Cologne, and Max Planck Institute for Neurological Research, Cologne, Germany
Neuroimage 21:136-43. 2004..The results support the concept that neocortical and amygdaloid functional changes of the cholinergic system are an early and leading event in AD, rather than the consequence of neurodegeneration of basal nuclei... - Introducing MASC: a movie for the assessment of social cognitionIsabel Dziobek
Center for Brain Health, New York University School of Medicine, New York, NY, USA
J Autism Dev Disord 36:623-36. 2006..Issues pertaining to the multidimensionality of the social cognition construct are discussed... - Screening for cognitive deficits in Parkinson's disease with the Parkinson neuropsychometric dementia assessment (PANDA) instrumentElke Kalbe
Department of Neurology, University Hospital, University of Cologne, Germany
Parkinsonism Relat Disord 14:93-101. 2008..The mood questionnaire also had high sensitivity and specificity. We conclude that the PANDA is an economical, easy-to-use and sensitive tool to detect neuropsychological dysfunctions in PD patients in clinical practice... - Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementiasLisa Mosconi
Center for Brain Health, New York University School of Medicine, New York, New York 10016, USA
J Nucl Med 49:390-8. 2008.... - Heterogeneity of brain glucose metabolism in mild cognitive impairment and clinical progression to Alzheimer diseaseDavide Anchisi
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele, Milan, Italy
Arch Neurol 62:1728-33. 2005..CONCLUSION: These data provide evidence for clinical and functional heterogeneity among subjects with aMCI and suggest that 18FDG-PET findings combined with memory scores may be useful in predicting short-term conversion to AD... - Neural correlates of anosognosia for cognitive impairment in Alzheimer's diseaseEric Salmon
Cyclotron Research Centre, University of Liege, Liege, Belgium
Hum Brain Mapp 27:588-97. 2006.... - Two aspects of impaired consciousness in Alzheimer's diseaseEric Salmon
Cyclotron Research Centre and Department of Neurology, University of Liege, B35 Sart Tilman, B4000 Liege, Belgium
Prog Brain Res 150:287-98. 2005..g., the temporoparietal junction). We hypothesize that these patients are impaired in the ability to see themselves with a third-person perspective (i.e., being able to see themselves as other people see them)... - Decision-making impairments in patients with pathological gamblingMatthias Brand
Department of Physiological Psychology, University of Bielefeld, P O Box 100131, 33501 Bielefeld, Germany
Psychiatry Res 133:91-9. 2005..Therefore, risky decisions of PG patients might be influenced by both dorsolateral prefrontal and orbitofrontal cortex dysfunctions... - Regional cerebral metabolism in early Alzheimer's disease with clinically significant apathy or depressionVjera A Holthoff
Department of Psychiatry and Psychotherapy, Dresden University of Technology, Germany
Biol Psychiatry 57:412-21. 2005..CONCLUSIONS: These findings support the notion that different functional circuits underlie apathy and depression in early AD... - Cerebral acetylcholine esterase activity in mild cognitive impairmentKarl Herholz
Department of Neurology, University of Cologne, Koln, Germany
Neuroreport 16:1431-4. 2005..These results suggest that low cortical acetylcholine esterase activity may be an indicator of impending dementia in patients with mild cognitive impairment... - Decision-making deficits of korsakoff patients in a new gambling task with explicit rules: associations with executive functionsMatthias Brand
Department of Physiological Psychology, University of Bielefeld, Bielefeld, Germany
Neuropsychology 19:267-77. 2005..Results show that Korsakoff patients are strongly impaired in this explicit decision-making task and that these disturbances are correlated with specific executive functions... - Cognitive estimation in patients with probable Alzheimer's disease and alcoholic Korsakoff patientsMatthias Brand
Department of Physiological Psychology, University of Bielefeld, PO Box 100131, Bielefeld 33501, Germany
Neuropsychologia 41:575-84. 2003.... - Cortical acetylcholine esterase activity and ApoE4-genotype in Alzheimer diseaseCarsten Eggers
Department of Neurology, University of Cologne, Germany
Neurosci Lett 408:46-50. 2006..041, p<0.05) in the ApoE4 negative group only. These results indicate that cortical AChE activity is relatively well preserved in ApoE4 carriers, either by preservation of its cellular expression or as AChE activity in amyloid plaques... - Organic and psychogenic factors leading to executive dysfunctions in a patient suffering from surgery of a colloid cyst of the Foramen of MonroMatthias Brand
Department of Physiological Psychology, University of Bielefeld, Bielefeld, Germany
Neurocase 10:420-5. 2004..The authors conclude that in this case decision-making deficits and executive dysfunctions are influenced by both organic and psychogenic factors... - Decision-making impairments in patients with Parkinson's diseaseMatthias Brand
Department of Physiological Psychology, University of Bielefeld, Bielefeld, Germany
Behav Neurol 15:77-85. 2004.... - Predominant ventromedial frontopolar metabolic impairment in frontotemporal dementiaEric Salmon
The Cyclotron Research Center, University of Liege, 4000 Liege, Belgium
Neuroimage 20:435-40. 2003.... - Subthalamic nucleus stimulation restores glucose metabolism in associative and limbic cortices and in cerebellum: evidence from a FDG-PET study in advanced Parkinson's diseaseRuediger Hilker
Departments of Neurology and dagger Stereotaxy and Functional Neurosurgery, University Hospital, Cologne, Germany
J Cereb Blood Flow Metab 24:7-16. 2004..These data suggest an activating effect of DBS upon its target structures and confirm a central role of the STN in motor as well as associative, limbic, and cerebellar basal ganglia circuits...