Research Topics
Species | M HasselmannSummaryAffiliation: Martin Luther University Country: Germany Publications
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Detail Information
Publications
Fine scale mapping in the sex locus region of the honey bee (Apis mellifera)M Hasselmann
Martin Luther Universitat Halle Wittenberg, Institut fur Zoologie, Molekulare Okologie, Biozentrum, Weinberg Weg 22, 06120 Halle, Germany
Insect Mol Biol 10:605-8. 2001..We show that distances less than 25 kb can be efficiently mapped with a mapping population of only 1000 individuals. The procedure described here will accelerate the mapping, analysis and isolation of honey bee genes...
Signatures of selection among sex-determining alleles of the honey beeMartin Hasselmann
Institut fur Zoologie, Biozentrum, Martin Luther Universitat Halle Wittenberg, Weinberg Weg 22, 06120 Halle, Germany
Proc Natl Acad Sci U S A 101:4888-93. 2004..Moreover, the first csd sequence data are a notable basis for the avoidance of diploid males in bee selection programs by allele-assisted breeding...
Specific developmental gene silencing in the honey bee using a homeobox motifM Beye
Martin Luther Universitat Halle Wittenberg, Biozentrum, Institut fur Zoologie, Molekulare Okologie, Halle, Germany
Insect Mol Biol 11:527-32. 2002..This is the first report of targeted disruption of gene function in the honey bee, and the results prove that the chosen target gene is a functional ortholog to engrailed in Drosophila...
The gene csd is the primary signal for sexual development in the honeybee and encodes an SR-type proteinMartin Beye
Martin Luther Universitat Halle Wittenberg, Institut fur Zoologie, Biozentrum, Weinberg Weg 22, 06120, Halle, Germany
Cell 114:419-29. 2003..Structural similarity of csd with tra genes of Dipteran insects suggests some functional relation of what would otherwise appear to be unrelated sex-determination mechanisms...
Patterns of conservation and change in honey bee developmental genesPeter K Dearden
Laboratory for Evolution and Development, Biochemistry Department, University of Otago, Dunedin, Aotearoa New Zealand
Genome Res 16:1376-84. 2006....
Evidence for convergent nucleotide evolution and high allelic turnover rates at the complementary sex determiner gene of Western and Asian honeybeesMartin Hasselmann
Heinrich Heine Universitaet Duesseldorf, Institut fuer Genetik, Universitaetsstr, Duesseldorf, Germany
Mol Biol Evol 25:696-708. 2008..e., N(e) < 10(4)), but not high mutation rates, can explain short maintenance times, implicating a strong historical impact of genetic drift on the molecular evolution of highly social honeybees...
Evidence for the evolutionary nascence of a novel sex determination pathway in honeybeesMartin Hasselmann
Department of Genetics, Heinrich Heine University Duesseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany
Nature 454:519-22. 2008..The fem locus in bees uncovers gene duplication and positive selection as evolutionary mechanisms underlying the origin of a novel sex determination pathway...
Pronounced differences of recombination activity at the sex determination locus of the honeybee, a locus under strong balancing selectionMartin Hasselmann
Heinrich Heine Universitat Dusseldorf, Institut fur Genetik, 40225 Dusseldorf, Germany
Genetics 174:1469-80. 2006..The homogenizing force of recombination is reduced within SDL, which preserves allelic differences and specificity, while the increase of recombination activity around SDL relaxes conflict between SDL and linked genes...
Exceptionally high levels of recombination across the honey bee genomeMartin Beye
Institute of Genetics, Heinrich Heine Universität Duesseldorf, Duesseldorf 40225, Germany
Genome Res 16:1339-44. 2006..Very few transposons and no retrotransposons are present in the high-recombining genome. We propose evolutionary explanations for the exceptionally high genome-wide recombination rate...
