Research Topics
Species | K WitterSummaryAffiliation: Klinikum Grosshadern Country: Germany Publications
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Detail Information
Publications
In a study for acne vulgaris, sequence-based HLA typing showed a novel DPB1 allele, DPB1*2402K Witter
Labor für Immungenetik, University Munich, Germany
Tissue Antigens 74:354-6. 2009..In consequence, codon 39 (68) TAC encodes for tyrosine in the novel allele instead of aspartic acid 39 (68) GAC in DPB1*0401...
HLA-DQB1*0319, a novel HLA-DQB1 allele, shows strong haplotype association to HLA-DRB1*1102K Witter
Laboratory of Immunogenetics, University Munich, Max Lebsche Platz 32, 81377 Munich, Germany
Tissue Antigens 70:73-5. 2007..The new allele shows a strong association to DRB1*1102, suggesting that the haplotype DRB1*1102-DQB1*0319 is quite common...
Bone marrow donor routine HLA typing identified a novel B*55 allele, B*5517, confirmed by allele-specific DNA cycle sequencingK Witter
Labor of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 66:58-60. 2005..The amino acid 127, leucine, is changed to valine, and the amino acid 140, also a leucine, is replaced by tyrosine in B*5517...
A novel HLA-B*55 allele, HLA-B*5514, found in a DNA sample derived from a bone marrow donorK Witter
Laboratory of Immunogenetics, University Munich, Paul Heyse Strasse 33, 80336 Munich, Germany
Tissue Antigens 65:500-2. 2005..Although this novel allele was added to the HLA-B*55 family by the Nomenclature Committee, the next related alleles were found in the HLA-B*56 group; HLA-B*5612 differing in six positions from HLA-B*5514 is the closest related allele...
A novel HLA-B*13 allele, B*1314, was found through routine HLA class I sequence-specific oligonucleotide typing and confirmed by sequence-based HLA typingK Witter
Labor of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 69:201-2. 2007..In this study, we report the identification of HLA-B*1314 that differs from B*130201 at two single nucleotide positions...
Routine HLA sequence-specific-oligonucleotide typing and confirming sequence-based typing of a prospective bone marrow donor identified a novel B*27 allele, HLA-B*2734K Witter
Labor of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 68:527-8. 2006..The amino acid asparagine is changed to aspartic acid in B*2734 allele. The second nucleotide exchange is a silent mutation and codon 163 remains unaffected as ACG-->ACA, still codes for alanine...
A novel HLA-DRB1 allele, HLA-DRB1*0465, was identified in a Hodgkin's lymphoma cell lineK Witter
Laboratory of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 71:257-8. 2008..This novel allele differs from the DRB1*0406 allele by a single nucleotide exchange at position 288 (211) (A-->T), which results in an arginine to tryptophan amino acid replacement at codon 90 in the new allele...
Bone marrow donor routine HLA typing identified a novel B*07 allele, B*0734, confirmed by allele-specific DNA cycle sequencingK Witter
Laboratory of Immunogenetics, University Munich, Paul Heyse Strasse 33, 80336 Munich, Germany
Tissue Antigens 65:497-9. 2005....
A novel A*24 allele, A*2442, was detected through routine bone marrow donor screeningK Witter
Labor of Immunogenetics, University Munich, 80336 Munich, Germany
Tissue Antigens 65:567-70. 2005..The second allele was determined to be A*0301. Further typing of this sample is B*1501 B*4001...
HLA-DQB1*0404, a novel DQB1-allele detected in a volunteer blood platelet donor typed for HLAK Witter
Labor für Immungenetik, Ludwig Maximilian Universitat Munchen, Munchen, Germany
Tissue Antigens 76:256-8. 2010..Introduction of a novel human leukocyte antigen-DQB1 allele, DQB1*0404, which featured one nucleotide mismatch in comparison with DQB1*0402...
HLA-B*1832, a novel B allele was found through high-resolution HLA typing of a Spanish blood donorK Witter
Laboratory of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 74:170-2. 2009....
Identification of a novel HLA-B*2722 allele from a Filipino cellK Witter
Labor of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 58:263-8. 2001..In exon 4 the B*2722 sequence is identical to B*2704. HLA-B*2704 differs from B*2706 in one base at position 704, a G in B*2704 and a C in B*2706, respectively...
A novel HLA-DRB1*11 allele, DRB1*1155, was found in a patient through routine DRB1 typing using sequence-specific primers (SSP) and confirmed by allele-specific sequence-based typingK Witter
Labor für Immungenetik, University Munich, Munich, Germany
Tissue Antigens 68:531-3. 2006..This results in a single amino acid exchange depending on the closest related allele investigated, whether DRB*1103 codon 74 alanine (GCG) is changed to leucine (CTG) or DRB1*1125 codon 71 arginine (GAG) is replaced with glutamic acid...
Sequence-based typing confirmed a novel B*40 allele, B*4046, which was identified through sequence-specific oligonucleotide hybridization routine typingK Witter
Labor für Immungenetik, University Munich, Paul Heyse Strasse 33, 80336 Munich, Germany
Tissue Antigens 63:378-81. 2004..This results in an amino acid substitution from threonine to alanine in B*4046 at codon 65, while codon 68 remains conserved and codon 69 "AAG" lysine is replaced by "GAG" glutamic acid in B*4046...
A novel HLA-DQB1*06 allele, DQB1*0628, found through routine sequence-based HLA typing and confirmation of DQB1*060302K Witter
Labor of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 69:102-3. 2007..In this paper we report the identification of human leukocyte antigen (HLA)-DQB1*0628 and the confirmation of HLA-DQB1*060302...
A novel B*38 allele, B*3809, was identified via sequence -based typing of B-cell line no. 299 of the UCLA International Cell ExchangeK Witter
Labor of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 62:548-50. 2003..299 from a Dutch Caucasoid donor and differs from B*3801 by mutation C-->G at position 483 in exon 3, resulting in an amino-acid substitution at codon 161 from aspartic acid in B*3801 to glutamic acid in B*3809, respectively...
Sequence-based typing identifies a novel HLA-DPB1 allele, DPB1*9601K Witter
Labor of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 62:185-7. 2003..This new allele has been submitted to the EMBL database and has been assigned the accession number AJ514871. The WHO Nomenclature Committee has officially assigned the name DPB1*9601...
Novel HLA-Cw*03 allele, Cw*030303, identified by nucleotide sequencingK Witter
Labor of Immunogenetics, University Munich, Munich, Germany
Tissue Antigens 62:179-81. 2003..This new allelic variant was confirmed by several other laboratories participating in the UCLA Terasaki Cell/DNA Exchange (3)...
