Research Topics
| Christian SorgSummaryAffiliation: Klinikum rechts der Isar Country: Germany Publications
| Collaborators
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Detail Information
Publications
Selective changes of resting-state networks in individuals at risk for Alzheimer's diseaseChristian Sorg
Department of Psychiatry, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaningerstrasse 22, 81675 Munich, Germany
Proc Natl Acad Sci U S A 104:18760-5. 2007..We interpret our finding as a proof of principle, demonstrating that functional brain disorders can be characterized by functional-disconnectivity profiles of RSNs...- Asymmetric loss of parietal activity causes spatial bias in prodromal and mild Alzheimer's diseaseChristian Sorg
Department of Psychiatry, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
Biol Psychiatry 71:798-804. 2012.... - Impact of Alzheimer's disease on the functional connectivity of spontaneous brain activityChristian Sorg
Department of Psychiatry, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
Curr Alzheimer Res 6:541-53. 2009..Finally, rs-fMRI seems to have the potential to produce connectivity-related biomarkers that distinguish AD and healthy aging... - Disconnection of frontal and parietal areas contributes to impaired attention in very early Alzheimer's diseaseSusanne Neufang
Department of Neuroradiology, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
J Alzheimers Dis 25:309-21. 2011..We conclude that, at very early stages of AD, the reduction of effective connectivity in fronto-parietal circuits is related to regional gray matter volume and contributes to impairments in top-down attentional control... - Repeated pain induces adaptations of intrinsic brain activity to reflect past and predict future painValentin Riedl
Department of Neurology, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany
Neuroimage 57:206-13. 2011..Other ICNs of the intrinsic architecture remained unchanged. Due to the ubiquitous occurrence of ICNs in several species, we suggest intrinsic brain activity as an integrative mechanism reflecting accumulated experiences... - Age-related cerebral perfusion changes in the parietal and temporal lobes measured by pulsed arterial spin labelingChristine Preibisch
Department of Neuroradiology, Technische Universitat Munchen, Munich, Germany Department of Neurology, Technische Universitat Munchen, Munchen, Germany
J Magn Reson Imaging 34:1295-302. 2011..To investigate age-related regional perfusion changes focused on the medial temporal lobes and related parietal areas using a pulsed arterial spin labeling technique... - Grey-matter atrophy in Alzheimer's disease is asymmetric but not lateralizedSabine Derflinger
Department of Neurology, Technische Universitat Munchen, Munich, Germany
J Alzheimers Dis 25:347-57. 2011..We conclude that, in principle, brain atrophy in AD is asymmetric rather than lateralized. At the individual level however, asymmetry contributes to cognitive deficits... - Cognitive rehabilitation in patients with mild cognitive impairmentAlexander Kurz
Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany
Int J Geriatr Psychiatry 24:163-8. 2009..To explore the benefits of a multi-component cognitive rehabilitation programme in patients with mild cognitive impairment (MCI)... - Complex activities of daily living in mild cognitive impairment: conceptual and diagnostic issuesRobert Perneczky
Department of Psychiatry, Technische Universitat Munchen, Germany
Age Ageing 35:240-5. 2006..The concept of an ADL threshold that separates MCI from dementia, however, appears to be improbable for several reasons... - Cerebrospinal fluid BACE1 activity and brain amyloid load in Alzheimer's diseaseTimo Grimmer
Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Street 22, 81675 Munchen, Germany
ScientificWorldJournal 2012:712048. 2012..Associations were found in areas close to the brain ventricles, which may have important implications for the use of BACE1 in CSF as a marker for AD pathology and for antiamyloid treatment monitoring... - [Von Economo neurons and insular cortex - the bridge between soma and psyche]Christian Sorg
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum rechts der Isar, Technische Universitat Munchen
Neuropsychiatr 24:64-6. 2010..It almost appears as if spindle cells would reach out from the realm of subconscious gut-feelings into the premises of conscious prefrontal planning... - Impairment of activities of daily living requiring memory or complex reasoning as part of the MCI syndromeRobert Perneczky
Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
Int J Geriatr Psychiatry 21:158-62. 2006..However, even mild degrees of cognitive deterioration are known to have negative effects on complex ADL... - A new integrative model of cerebral activation, deactivation and default mode function in Alzheimer's diseaseMarc Wermke
Department of Nuclear Medicine, Technische Universitat Munchen, Ismaninger Strasse 22, Munich, Germany
Eur J Nucl Med Mol Imaging 35:S12-24. 2008..A new comprehensive model will be introduced integrating these heterogeneous findings and explaining their impact on cognitive performance... - Progression of cerebral amyloid load is associated with the apolipoprotein E ?4 genotype in Alzheimer's diseaseTimo Grimmer
Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Federal Republic of Germany
Biol Psychiatry 68:879-84. 2010..Only few data have been published on in vivo longitudinal changes of amyloid load in Alzheimer's disease (AD) patients, with conflicting results. Therefore, little is known about the factors that influence these changes... - Patients with pain disorder show gray-matter loss in pain-processing structures: a voxel-based morphometric studyMichael Valet
Neurologische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munchen, Germany
Psychosom Med 71:49-56. 2009..Psychological factors are thought to play a major role. Recent neuroimaging studies evidenced altered pain processing in patients suffering from this disorder...