Research Topics
Species | Yingying ZhangSummaryAffiliation: Jacobs University Bremen Country: Germany Publications
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Detail Information
Publications
Non-imprinted allele-specific DNA methylation on human autosomesYingying Zhang
School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D 28759 Bremen, Germany
Genome Biol 10:R138. 2009..Differential DNA methylation between alleles is well established in imprinted genes and the X chromosomes in females but has rarely been reported at non-imprinted loci on autosomes...
DNA methylation analysis by bisulfite conversion, cloning, and sequencing of individual clonesYingying Zhang
School of Engineering and Science, Jacobs University Bremen, Bremen, Germany
Methods Mol Biol 507:177-87. 2009..In addition, we present tools for the web display of primary data and data analysis (BiQ Analyzer, BDPC) and describe the setup of a sequencing and analysis pipeline for medium to high throughput...
BISMA--fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequencesChristian Rohde
School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, 28725 Bremen, Germany
BMC Bioinformatics 11:230. 2010..A region of interest is targeted by PCR and about 20-50 subcloned DNA molecules are usually analyzed, to determine the methylation status at single CpG sites and molecule resolution...
New clustering module in BDPC bisulfite sequencing data presentation and compilation web application for DNA methylation analysesChristian Rohde
School of Engineering and Science, Jacobs University Bremen, Bremen, Germany
Biotechniques 47:781-3. 2009..It can also be used for data not processed by BDPC. In addition, several functions of the existing BDPC compilation module have been improved...
DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolutionYingying Zhang
School of Engineering and Science, Jacobs University Bremen, Bremen, Germany
PLoS Genet 5:e1000438. 2009..Further, we illustrate genotype-epigenotype interactions by showing novel examples of allele-specific methylation...
Bisulfite sequencing Data Presentation and Compilation (BDPC) web server--a useful tool for DNA methylation analysisChristian Rohde
School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, 28725 Bremen, Germany
Nucleic Acids Res 36:e34. 2008..v) A condensed file, containing all primary data in simplified format for further downstream data analysis and (vi) a custom track file for display of the results in the UCSC genome browser...
DNA methyltransferase assaysRenata Z Jurkowska
Biochemistry Lab, School of Engineering and Science, Jacobs University Bremen, Bremen, Germany
Methods Mol Biol 791:157-77. 2011..3) A novel fluorescence-coupled, restriction-based assay suitable for high-throughput screening of DNA methyltransferase inhibitors...
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tailYingying Zhang
Biochemistry Laboratory, School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany
Nucleic Acids Res 38:4246-53. 2010..Our in vitro results recapitulate DNA methylation patterns observed in genome-wide DNA methylation studies...
