Research Topics
| Ch C ZouboulisSummaryAffiliation: Humboldt University Country: Germany Publications
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Detail Information
Publications
Ocular involvement in Adamantiades-Behçet's disease in Berlin, GermanyLothar Krause
Department of Ophthalmology, Charite Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany
Graefes Arch Clin Exp Ophthalmol 247:661-6. 2009..Berlin is the city with the highest number of non-native German inhabitants, and its multi-ethnic character renders it uniquely appropriate for epidemiological studies on ABD...- Androgen action on human skin -- from basic research to clinical significanceChristos C Zouboulis
Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
Exp Dermatol 13:5-10. 2004..Partial effectiveness has only been achieved either by androgen depletion, inhibition of androgen metabolism or blockade of the androgen receptor... - [Cryosurgical treatment of actinic keratoses and evidence-based review]C C Zouboulis
Klinik und Hochschulambulanz für Dermatologie, Campus Benjamin Franklin der Charité Universitätsmedizin, Berlin
Hautarzt 56:353-8. 2005..In the USA, cryosurgery is the most frequent surgical procedure for the treatment of actinic keratoses and considered the treatment of choice... - Acne and sebaceous gland functionChristos C Zouboulis
Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Fabeckstrasse 60 62, 14195 Berlin, Germany
Clin Dermatol 22:360-6. 2004..They should also influence peroxisome proliferator-activated receptor regulation. Isotretinoin is still the most active available drug for the treatment of severe acne... - Zileuton, an oral 5-lipoxygenase inhibitor, directly reduces sebum productionCh C Zouboulis
Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
Dermatology 210:36-8. 2005..Zileuton, a 5-lipoxygenase inhibitor, reduces the number of inflammatory lesions in moderate acne and inhibits the synthesis of sebaceous lipids... - Neuroendocrine regulation of sebocytes -- a pathogenetic link between stress and acneChristos C Zouboulis
Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
Exp Dermatol 13:31-5. 2004..By means of their autocrine, paracrine and endocrine actions, these neuroendocrine factors appear to mediate centrally and topically induced stress towards the sebaceous gland, ultimately affecting the clinical course of acne... - Extended venous thrombosis in Adamantiades-Behçet's diseaseChristos C Zouboulis
Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Fabeckstrasse 60 62 14195 Berlin, Germany
Eur J Dermatol 14:268-71. 2004..During the 52-month follow-up single oral aphthous ulcers were occasionally observed and erythema nodosum-like lesions and skin pustules occurred at the lower extremities two weeks after a temporary discontinuation of treatment... - Interferon alfa-2a in the treatment of ocular Adamantiades-Behçet's diseaseLothar Krause
Department of Ophthalmology, University Medical Center Benjamin Franklin, , Berlin, Germany
Adv Exp Med Biol 528:511-9. 2003 - Longterm visual prognosis of patients with ocular Adamantiades-Behçet's disease treated with interferon-alpha-2aLothar Krause
Department of Ophthalmology, Charite Universitaetsmedizin Berlin, Berlin, Germany
J Rheumatol 35:896-903. 2008..Interferon-alpha (IFN-alpha) has proven to be effective in mucocutaneous ABD and has been reported to improve ocular lesions. We examined the longterm effects of IFN-alpha-2a in a case series of 45 patients with ocular involvement... - Intraocular surgery under systemic interferon-alpha therapy in ocular Adamantiades-Behçet's diseaseLothar Krause
Department of Ophthalmology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
Graefes Arch Clin Exp Ophthalmol 245:1617-21. 2007..In some cases, such as tractional retinal detachment, secondary glaucoma or secondary cataract formation, intraocular surgery is required... - The sebocyte culture: a model to study the pathophysiology of the sebaceous gland in sebostasis, seborrhoea and acneChristos C Zouboulis
Department of Dermatology, Dessau Medical Center, Dessau, Germany
Arch Dermatol Res 300:397-413. 2008..This article summarizes the data of newest research of sebostasis, seborrhoea and acne made possible through the development of human and animal sebocyte culture models... - Impressive skin manifestation of systemic sarcoidosisA M H A Janitha P Chandani
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Fabeckstrasse 60-62, 14195 Berlin, Germany
Int J Dermatol 41:232-6. 2002 - Frontiers in sebaceous gland biology and pathologyChristos C Zouboulis
Department of Dermatology, Dessau Medical Center, Dessau, Germany
Exp Dermatol 17:542-51. 2008..These multiple homeostatic functions award the sebaceous gland the role 'brain of the skin' and the most important cutaneous endocrine gland... - Psychophysiological reactivity under mental stress in atopic dermatitisKristina Seiffert
Department of Psychosomatics and Psychotherapy, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
Dermatology 210:286-93. 2005..An association of mental stress with atopic dermatitis is widely accepted. However, no long-term evaluation of psychophysiological reactivity over the course of disease has yet been performed... - Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glandsTheodosios Alestas
Department of Dermatology, , Campus Benjamin Franklin, Fabeckstrasse 60-62, 14195 Berlin, Germany
J Mol Med 84:75-87. 2006..In conclusion, human sebocytes possess the enzyme machinery for functional leukotriene and prostaglandin pathways. A comprehensive link between inflammation and sebaceous lipid synthesis is provided... - [Epidemiology and clinical manifestations of Adamantiades-Behçet disease in Germany -- current pathogenetic concepts and therapeutic possibilities]Andreas Altenburg
Clinic for Dermatology, Venerology and Allergology, , Campus Benjamin Franklin, Berlin
J Dtsch Dermatol Ges 4:49-64; quiz 65-6. 2006 - Aging of human sebocytes in vitro induced by exposure to a defined hormone environmentEvgenia Makrantonaki
Laboratory for Biogerontology, Dermato-Pharmacology and Dermato-Endocrinology, Institute of Clinical Pharmacology and Toxicology, , Campus Benjamin Franklin, Berlin, Germany
Dermatology 213:262-3. 2006 - Interplay of IGF-I and 17beta-estradiol at age-specific levels in human sebocytes and fibroblasts in vitroEvgenia Makrantonaki
Laboratory for Biogerontology, Dermato Pharmacology and Dermato Endocrinology, Institute of Clinical Pharmacology and Toxicology, Charite Universitaetsmedizin Berlin, Berlin, Germany
Exp Gerontol 43:939-46. 2008..In conclusion, IGF-I is a key regulator of human skin aging and declining IGF-I levels with age may play a significant role in the reduction of skin surface lipids and thickness... - Study of the efficacy, tolerability, and safety of 2 fixed-dose combination gels in the management of acne vulgarisChristos C Zouboulis
Department of Dermatology, Dessau Medical Center, Auenweg 38, 06847 Dessau, Germany
Cutis 84:223-9. 2009.... - KdPT, a tripeptide derivative of alpha-melanocyte-stimulating hormone, suppresses IL-1 beta-mediated cytokine expression and signaling in human sebocytesArianna Mastrofrancesco
Department of Dermatology, University of Munster, Munster, Germany
J Immunol 185:1903-11. 2010..Our data demonstrate a promising anti-inflammatory potential of KdPT and point toward novel future directions in the treatment of acne-as well as of various other IL-1-mediated inflammatory diseases-with this small molecule... - A historical review of Adamantiades-Behçet's diseaseChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Germany
Adv Exp Med Biol 528:7-14. 2003 - A historical review of early descriptions of Adamantiades-Behçet's diseaseChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Fabeckstrasse 60-62, 14195 Berlin, Germany
J Invest Dermatol 119:201-5. 2002 - Univariate and multivariate analyses comparing demographic, genetic, clinical, and serological risk factors for severe Adamantiades-Behçet's diseaseChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Berlin, Germany
Adv Exp Med Biol 528:123-6. 2003 - Characterization of the vitamin D endocrine system in human sebocytes in vitroChristina Krämer
Department of Dermatology, The Saarland University Hospital, 66421 Homburg Saar, Germany
J Steroid Biochem Mol Biol 113:9-16. 2009..We conclude that sebaceous glands represent potential targets for therapy with vitamin D analogues or for pharmacological modulation of 1,25(OH)(2)D(3) synthesis/metabolism... - Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitroEvgenia Makrantonaki
Laboratory for Biogerontology, Dermato-Pharmacology and Dermato-Endocrinology, Institute of Clinical Pharmacology and Toxicology, , Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
Aging Cell 5:331-44. 2006.... - Isotretinoin revisited: pluripotent effects on human sebaceous gland cellsChristos C Zouboulis
Department of Dermatology, Dessau Medical Center, Dessau, Germany
J Invest Dermatol 126:2154-6. 2006..These events were specific to sebocytes, as isotretinoin failed to induce apoptosis in keratinocytes. Isotretinoin-induced apoptosis was shown to be an RAR-independent mechanism... - Nicotine and biochanin A, but not cigarette smoke, induce anti-inflammatory effects on keratinocytes and endothelial cells in patients with Behçet's diseaseAylin Kalayciyan
Department of Dermatology, Charite Universitaetsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
J Invest Dermatol 127:81-9. 2007..Moreover, biochanin A is likely to exhibit similar and even more profound results than nicotine... - Update and future of systemic acne treatmentChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Berlin, Germany
Dermatology 206:37-53. 2003.... - Differential regulation of Toll-like receptor and CD14 pathways by retinoids and corticosteroids in human sebocytesMarina K Oeff
Department of Dermatology, , Campus Benjamin Franklin, Berlin, Germany
Dermatology 213:266. 2006 - Corticotropin-releasing hormone: an autocrine hormone that promotes lipogenesis in human sebocytesChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, 14195 Berlin, Germany
Proc Natl Acad Sci U S A 99:7148-53. 2002..The findings implicate CRH in the clinical development of acne, seborrhea, androgenetic alopecia, skin aging, xerosis, and other skin disorders associated with alterations in lipid formation of sebaceous origin... - Anti-acne agents attenuate FGFR2 signal transduction in acneBodo C Melnik
Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabruck, Osnabruck, Germany
J Invest Dermatol 129:1868-77. 2009.... - Benediktos Adamantiades and his forgotten contributions to medicineChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Fabeckstrasse 60 62, 14195 Berlin, Germany
Eur J Dermatol 12:471-4. 2002..Adamantiades compiled over 150 scientific papers many of which marked a new stage in his field. He died in 1962 in Athens... - Pathogenesis of Adamantiades-Behçet's diseaseChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Germany
Med Microbiol Immunol 192:149-55. 2003..Endothelial activation leading to a chronic local inflammation process together with platelet and serum factors enhance coagulation and thrombosis... - Human skin stem cells and the ageing processChristos C Zouboulis
Department of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Dessau, Germany
Exp Gerontol 43:986-97. 2008..In addition, they provide in vitro models to study epidermal lineage selection and its role in the ageing process... - Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: particle characterisation and skin uptakeJana Stecová
Institut fur Pharmazie, Freie Universitat Berlin, Konigin Luise Strasse 2 4, D 14195, Berlin, Germany
Pharm Res 24:991-1000. 2007..To improve skin penetration of the poorly absorbed drug, we intended to identify the active moiety and to load it to particulate carrier systems... - The William J. Cunliffe Scientific AwardsChristos C Zouboulis
Department of Dermatology, , Germany
Dermatology 211:191-2. 2005 - Sebaceous glands and the prostaglandin pathway--key stones of an exciting mosaicChristos C Zouboulis
Department of Dermatology, , Campus Benjamin Franklin, Berlin, Germany
J Invest Dermatol 125:x-xi. 2005 - [Severe erythrodermic psoriasis in a patient with 22q11 deletion syndrome]Jan C Preiss
Medizinische Klinik I (Gastroenterologie, Infektiologie, Rheumatologie, , Campus Benjamin Franklin, Berlin
Med Klin (Munich) 100:275-8. 2005..This case report suggests that calcium can be involved in psoriasis pathogenesis at least in a subgroup of patients and that systemic retinoids exhibit insufficient effectiveness under low serum albumin levels... - Oral alitretinoin (9-cis-retinoic acid) therapy for chronic hand dermatitis in patients refractory to standard therapy: results of a randomized, double-blind, placebo-controlled, multicenter trialThomas Ruzicka
Department of Dermatology, Heinrich Heine University Hospital, Dusseldorf, Germany
Arch Dermatol 140:1453-9. 2004..To assess the efficacy and safety of oral alitretinoin (9-cis-retinoic acid), 10 mg/d, 20 mg/d, and 40 mg/d, compared with placebo control, in the treatment of chronic hand dermatitis... - Pathogenesis of Adamantiades-Behçet's diseaseChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Berlin, Germany
Adv Exp Med Biol 528:161-71. 2003 - Association of Mycoplasma fermentans with Adamantiades-Behçet's diseaseChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Berlin, Germany
Adv Exp Med Biol 528:191-4. 2003 - Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoinEleni Papakonstantinou
Department of Pharmacology, School of Medicine, Aristotle University, Thessaloniki, Greece
J Invest Dermatol 125:673-84. 2005..These data indicate that MMP and TIMP of epithelial origin may be involved in acne pathogenesis, and that isotretinoin-induced reduction in MMP-9 and -13 may contribute to the therapeutic effects of the agent in acne... - Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytesEdward Pelle
Estee Lauder Research Laboratories, Melville, New York 11747, USA
J Invest Dermatol 128:1280-5. 2008.... - Increased in situ expression of melanocortin-1 receptor in sebaceous glands of lesional skin of patients with acne vulgarisRuta Ganceviciene
Centre of Dermatovenereology, Vilnius University Hospital, Santariskiu Klinikos, Vilnius, Lithuania
Exp Dermatol 16:547-52. 2007..These data suggest that melanocortin-1 receptor is involved in the pathogenesis of acne... - A new concept for acne therapy: a pilot study with zileuton, an oral 5-lipoxygenase inhibitorChristos C Zouboulis
Arch Dermatol 139:668-70. 2003 - Vitrectomy and trabeculectomy combined with interferon alpha treatment in Adamantiades-Behçet's disease: a case reportLothar Krause
Department of Ophthalmology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
Graefes Arch Clin Exp Ophthalmol 241:871-4. 2003..Left untreated, it leads to blindness and often to loss of the eye through secondary complications such as phthisis or painful glaucoma... - Modification of a device and its application for intralesional cryosurgery of old recalcitrant keloidsChristos C Zouboulis
Arch Dermatol 140:1293-4. 2004 - Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-cateninCristina Lo Celso
Massachusetts General Hospital, Center for Regenerative Medicine, Boston, Massachusetts, USA
Stem Cells 26:1241-52. 2008..Our studies provide evidence for a bipotential epidermal stem cell population in an in vitro model of human epidermal lineage selection and highlight the importance of Myc as a regulator of sebocyte differentiation... - Cutaneous androgen metabolism: basic research and clinical perspectivesWenChieh Chen
Department of Dermatology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
J Invest Dermatol 119:992-1007. 2002..Pharmacologic development of more potent specific isoenzyme antagonists may lead to better clinical treatment or even prevention of androgen-dependent dermatoses... - HLA-independent antibacterial host response toward Th1 immunity mediated by IL-12: a new concept for the pathogenesis of Adamantiades-Behçet's diseaseChristos C Zouboulis
Department of Dermatology and Immunology, Dessau Medical Center, Dessau, Germany
J Invest Dermatol 126:1444-7. 2006..The authors provide evidence for an antibacterial host response toward T-helper type 1 immunity mediated by IL-12 in patients with ABD, which is HLA independent... - Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signalingNóra Dobrosi
Department of Physiology, University of Debrecen, Medical and Health Science Center, 4032 Debrecen, Nagyerdei krt 98 PO Box 22, Hungary
FASEB J 22:3685-95. 2008..CB2 antagonists or agonists therefore deserve to be explored in the management of skin disorders characterized by sebaceous gland dysfunctions (e.g., acne vulgaris, seborrhea, dry skin)... - The truth behind this undeniable efficacy--recurrence rates and relapse risk factors of acne treatment with oral isotretinoinChristos C Zouboulis
Dermatology 212:99-100. 2006 - Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiationAnja Thielitz
Department of Dermatology and Venereology, Otto von Guericke University Magdeburg, Magdeburg, Germany
J Invest Dermatol 127:1042-51. 2007.... - Possible role of DP IV inhibitors in acne therapyAnja Thielitz
Department of Dermatology and Venereology, Otto-von-Guericke University, Leipziger Str. 44, D-39120 Magdeburg, Germany
Adv Exp Med Biol 575:163-7. 2006 - Current developments and uses of cryosurgery in the treatment of keloids and hypertrophic scarsChristos C Zouboulis
Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Berlin, Germany
Wound Repair Regen 10:98-102. 2002 - Targeting of sebocytes by aminolevulinic acid-dependent photosensitizationSachiko Kosaka
Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Photochem Photobiol 82:453-7. 2006..In addition to weak mitochondrial and strong membrane fluorescence, distinctive spots with strong fluorescence were observed. These did not colocalize with fluorescent probes for mitochondria, lysosomes or the Golgi apparati... - Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytesWenChieh Chen
Department of Dermatology, College of Medicine, National Cheng Kung University, Sheng Li Road 138, 704 Tainan, Taiwan
J Invest Dermatol 121:441-7. 2003..Treatment with linoleic acid for 48 h induced further differentiation of sebocytes leading to abundant lipid synthesis... - Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situMarkus Bohm
Department of Dermatology and Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Munster, Munster, Germany
J Invest Dermatol 118:533-9. 2002..By modulating interleukin-8 secretion, alpha-melanocyte-stimulating hormone may act as a modulator of inflammatory responses in the pilosebaceous unit... - Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytesIstvan Nagy
Department of Dermatology and Allergology, University of Szeged, Koranyi fasor 6, 6720 Szeged, Hungary
Microbes Infect 8:2195-205. 2006..acnes vary in their capacity to stimulate an inflammatory response within the pilosebaceous follicle... - High seroprevalence of anti-Mycoplasma fermentans antibodies in patients with malignant aphthosisChristos C Zouboulis
J Invest Dermatol 121:211-2. 2003 - Potent corticosteroids inhibit lipogenesis in sebaceous glandsWenChieh Chen
Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung, Chang Gung University, Taoyuon, Taiwan
Dermatology 213:264-5. 2006 - Follicular drug eruption induced by gefitinib (ZD 1839, iressa): clinical picture correlates with in vitro data of focal epidermal necrosis after epidermal growth factor inhibition in skin culturesRegina Treudler
Dermatology 211:375-6. 2005 - Psoriasin and follicular hyperkeratinization in acne comedonesRuta Ganceviciene
Department of Dermatology, Vilnius University Hospital, Santariskiu Klinikos, Vilnius, Lithuania
Dermatology 213:270-2. 2006 - Expression of lipogenic factors galectin-12, resistin, SREBP-1, and SCD in human sebaceous glands and cultured sebocytesWesley J Harrison
Centre for Cutaneous Research, Barts and The London, Queen Mary s School of Medicine and Dentistry, London, UK
J Invest Dermatol 127:1309-17. 2007.... - Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgarisMonica Ottaviani
San Gallicano Dermatological Institute IRCCS, Rome, Italy
J Invest Dermatol 126:2430-7. 2006.... - Expression of sex-determining genes in the scalp of men with androgenetic alopeciaWenChieh Chen
Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC
Dermatology 214:199-204. 2007..The regulation of the cutaneous steroidogenesis in patients with androgenetic alopecia remains largely unclear... - Activation of platelet-activating factor receptor in SZ95 sebocytes results in inflammatory cytokine and prostaglandin E2 productionQiwei Zhang
Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Exp Dermatol 15:769-74. 2006..These studies suggest that SZ95 sebocytes express functional PAF-Rs and PAF-Rs are involved in regulating the expression of inflammatory mediators, including COX-2, PGE(2) and IL-8... - Involvement of PPARgamma in oxidative stress-mediated prostaglandin E(2) production in SZ95 human sebaceous gland cellsQiwei Zhang
Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Invest Dermatol 126:42-8. 2006..This study illustrates the importance of the PPARgamma system in regulating cellular responses to oxidative stress... - Characterization of liver X receptor expression and function in human skin and the pilosebaceous unitLouise E Russell
Centre for Cutaneous Research and Centre for Endocrinology, Bart s and the London Queen Mary s School of Medicine and Dentistry, Queen Mary College, University of London, London, UK
Exp Dermatol 16:844-52. 2007..In addition, we showed that the synthetic agonist TO901317 significantly reduced hair growth, in vitro... - Receptors of eccrine, apocrine, and holocrine skin glandsUwe Wollina
Department of Dermatology and Allergology, Academic Teaching Hospital Dresden Friedrichstadt, Friedrichstrasse 41, 01067 Dresden, Germany
Dermatol Clin 25:577-88, ix. 2007..The knowledge of ligand receptor interactions in these specialized skin structures might offer not only a better understanding of their pathology, but also new therapeutic options... - LXRalpha enhances lipid synthesis in SZ95 sebocytesIl Hong
College of Pharmacy and Bio MAX Institute, Seoul National University, Seoul, Korea
J Invest Dermatol 128:1266-72. 2008..Thus, we suggest that LXR ligands could provide a new class of therapeutic agents for sebaceous gland-associated disorders such as seborrhea and acne... - Sebocytes express functional cathelicidin antimicrobial peptides and can act to kill propionibacterium acnesDong-Youn Lee
J Invest Dermatol 128:1863-6. 2008