Research Topics
| Zofia Von MarschallSummaryAffiliation: Humboldt University Country: Germany Publications
| Collaborators
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Detail Information
Publications
Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancerZofia Von Marschall
Department of Hepatology, Gastroenterology, Endocrinology and Metabolism, Charite University Medicine Berlin, CVK, D 13353 Berlin, Germany
Int J Oncol 27:669-79. 2005..Our results suggest that VEGF-D plays a pivotal role in stimulating lymphangiogenesis and lymphatic metastasis in human ductal pancreatic cancer, and therefore represents a novel therapeutic target for this devastating disease...
Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesisZofia Von Marschall
Department of Hepatology, Gastroenterology, Endocrinology and Metabolism, Charit, Campus Virchow-Klinikum, Humboldt-University, Berlin, Germany
J Natl Cancer Inst 95:437-48. 2003..CONCLUSION: IFN-alpha confers its antitumor activity, at least in part, by its antiangiogenic activity, which results from Sp1- and/or Sp3-mediated inhibition of VEGF gene transcription...
VEGF-D promotes tumor growth and lymphatic spread in a mouse model of hepatocellular carcinomaArmin Thelen
Department of General, Visceral and Transplantation Surgery, Campus Virchow Klinikum, Charite Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Int J Cancer 122:2471-81. 2008..In conclusion, our study suggests that expression of VEGF-D is involved in growth and lymphatic spread of HCC. Therefore, VEGF-D might represent a therapeutic target in HCC...
Angiopoietin-2 drives lymphatic metastasis of pancreatic cancerPetra Schulz
Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, D 13353 Berlin, Germany
FASEB J 25:3325-35. 2011..0005). These findings indicate that Ang-2 participates in the control of lymphatic metastasis, constitutes a noninvasive prognostic biomarker, and may provide an accessible therapeutic target in PDAC...
Overexpression of pRB in human pancreatic carcinoma cells: function in chemotherapy-induced apoptosisThomas Plath
T. Plath, M. Peters, K. Detjen, M. Welzel, Z. von Marschall, B. Wiedenmann, S. Rosewicz (Department of Hepatology and Gastroenterology, C. Radke (Department of Pathology, Charit, Campus Virchow-Klinikum, Humboldt-University, Berlin, Germany
J Natl Cancer Inst 94:129-42. 2002..CONCLUSIONS: Overexpression of pRB is associated with human pancreatic duct-cell cancer and may allow pancreatic cancer cells to evade chemotherapy-induced apoptosis...
Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cellsChristoph Benckert
Department of General Visceral and Transplantation Surgery, Charit, Humboldt-University, 13353 Berlin, Germany
Cancer Res 63:1083-92. 2003..These data suggest that overexpression and functional interaction of TGF-beta 1 and VEGF might contribute to the "angiogenic switch" and the malignant phenotype in human CCC...
