Ulrich Speck

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi Drug delivery by angiographic contrast media: inhibition of restenosis
    Ulrich Speck
    Dept. of Radiology, , Berlin, Germany
    Acad Radiol 12:S14-7. 2005
  2. ncbi Neointima inhibition: comparison of effectiveness of non-stent-based local drug delivery and a drug-eluting stent in porcine coronary arteries
    Ulrich Speck
    Department of Radiology, Charite Humboldt University Berlin, Schumannstr 20 21, D 10117 Berlin, Germany
    Radiology 240:411-8. 2006
  3. ncbi Inhibition of restenosis in stented porcine coronary arteries: uptake of Paclitaxel from angiographic contrast media
    Ulrich Speck
    Department of Radiology, Charite, Humboldt University, Berlin, Germany
    Invest Radiol 39:182-6. 2004
  4. ncbi Local drug delivery - the early Berlin experience: single drug administration versus sustained release
    Ulrich Speck
    Department of Radiology, Experimental Radiology, Charite, University Hospital, Berlin, Germany
    EuroIntervention 7:K17-22. 2011
  5. ncbi Pilot study on basophil activation induced by contrast medium
    Ingrid Böhm
    Center for Molecular Imaging Research MBMB, Department of Radiology, Philipps University of Marburg, Germany
    Fundam Clin Pharmacol 25:267-76. 2011
  6. ncbi A possible role for cysteinyl-leukotrienes in non-ionic contrast media induced adverse reactions
    Ingrid Böhm
    Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Eur J Radiol 55:431-6. 2005
  7. ncbi Inhibition of restenosis in femoropopliteal arteries: paclitaxel-coated versus uncoated balloon: femoral paclitaxel randomized pilot trial
    Michael Werk
    Charite, Universitatsmedizin Berlin, Martin Luther Krankenhaus, Department of Radiology, Berlin, Germany
    Circulation 118:1358-65. 2008
  8. ncbi Reduction of stenosis due to intimal hyperplasia after stent supported angioplasty of peripheral arteries by local administration of paclitaxel in swine
    Thomas Albrecht
    Department of Radiology and Nuclear Medicine, Campus Benjamin Franklin, Charite, Free University und Humboldt University Berlin, Berlin, Germany
    Invest Radiol 42:579-85. 2007
  9. ncbi Adverse events after unenhanced and monomeric and dimeric contrast-enhanced CT: a prospective randomized controlled trial
    Hans H Schild
    Department of Radiology, University of Bonn, Hospital and Medical School, Sigmund Freud Str 25, 53105 Bonn, Germany
    Radiology 240:56-64. 2006
  10. ncbi Dose response to Paclitaxel-coated balloon catheters in the porcine coronary overstretch and stent implantation model
    Bettina Kelsch
    Department of Radiology, Charite, Humboldt University Berlin, Berlin, Germany
    Invest Radiol 46:255-63. 2011

Detail Information

Publications23

  1. ncbi Drug delivery by angiographic contrast media: inhibition of restenosis
    Ulrich Speck
    Dept. of Radiology, , Berlin, Germany
    Acad Radiol 12:S14-7. 2005
  2. ncbi Neointima inhibition: comparison of effectiveness of non-stent-based local drug delivery and a drug-eluting stent in porcine coronary arteries
    Ulrich Speck
    Department of Radiology, Charite Humboldt University Berlin, Schumannstr 20 21, D 10117 Berlin, Germany
    Radiology 240:411-8. 2006
    ..To compare the inhibition of neointimal proliferation by using non-stent-based local drug delivery and a drug-eluting stent in porcine coronary arteries...
  3. ncbi Inhibition of restenosis in stented porcine coronary arteries: uptake of Paclitaxel from angiographic contrast media
    Ulrich Speck
    Department of Radiology, Charite, Humboldt University, Berlin, Germany
    Invest Radiol 39:182-6. 2004
    ..This study determined early local tissue concentrations after the administration of different paclitaxel doses and preparations...
  4. ncbi Local drug delivery - the early Berlin experience: single drug administration versus sustained release
    Ulrich Speck
    Department of Radiology, Experimental Radiology, Charite, University Hospital, Berlin, Germany
    EuroIntervention 7:K17-22. 2011
    ....
  5. ncbi Pilot study on basophil activation induced by contrast medium
    Ingrid Böhm
    Center for Molecular Imaging Research MBMB, Department of Radiology, Philipps University of Marburg, Germany
    Fundam Clin Pharmacol 25:267-76. 2011
    ..Analysis of CD63 expression by using fluorescence activated cell sorter-analysis is an interesting new tool to elucidate the complex conditions leading to CM-mediated hypersensitivity reactions...
  6. ncbi A possible role for cysteinyl-leukotrienes in non-ionic contrast media induced adverse reactions
    Ingrid Böhm
    Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Eur J Radiol 55:431-6. 2005
    ..To test whether mono- or dimeric X-ray contrast media (CM) may induce the de novo production of cysteinyl-leukotriens (cys-LT), that could contribute to allergic/allergy-like side effects...
  7. ncbi Inhibition of restenosis in femoropopliteal arteries: paclitaxel-coated versus uncoated balloon: femoral paclitaxel randomized pilot trial
    Michael Werk
    Charite, Universitatsmedizin Berlin, Martin Luther Krankenhaus, Department of Radiology, Berlin, Germany
    Circulation 118:1358-65. 2008
    ..The success of percutaneous intervention in peripheral arterial disease is limited by restenosis. The aim of the present pilot study was to evaluate a novel method of local drug delivery...
  8. ncbi Reduction of stenosis due to intimal hyperplasia after stent supported angioplasty of peripheral arteries by local administration of paclitaxel in swine
    Thomas Albrecht
    Department of Radiology and Nuclear Medicine, Campus Benjamin Franklin, Charite, Free University und Humboldt University Berlin, Berlin, Germany
    Invest Radiol 42:579-85. 2007
    ....
  9. ncbi Adverse events after unenhanced and monomeric and dimeric contrast-enhanced CT: a prospective randomized controlled trial
    Hans H Schild
    Department of Radiology, University of Bonn, Hospital and Medical School, Sigmund Freud Str 25, 53105 Bonn, Germany
    Radiology 240:56-64. 2006
    ..To prospectively evaluate adverse events (AEs) in patients who underwent nonionic monomeric or dimeric contrast media-enhanced computed tomography (CT) and to compare these effects with AEs in patients who underwent unenhanced CT...
  10. ncbi Dose response to Paclitaxel-coated balloon catheters in the porcine coronary overstretch and stent implantation model
    Bettina Kelsch
    Department of Radiology, Charite, Humboldt University Berlin, Berlin, Germany
    Invest Radiol 46:255-63. 2011
    ....
  11. ncbi No difference among modern contrast media's effect on neointimal proliferation and restenosis after coronary stenting in pigs
    Wolfram Clauss
    Schering AG, Berlin, Germany
    Invest Radiol 38:743-9. 2003
    ..CONCLUSIONS: Under the experimental conditions iopromide, ioxaglate, and iosimenol had no or very similar direct or otherwise mediated effect on cell proliferation and restenosis...
  12. ncbi Contrast-to-noise ratios of different elements in digital mammography: evaluation of their potential as new contrast agents
    Felix Diekmann
    Department of Radiology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Invest Radiol 42:319-25. 2007
    ..The elements investigated included not only elements already used in conventional contrast agents such as gadolinium and iodine but also other elements to investigate their potential as mammographic contrast agents...
  13. ncbi Laser-induced thermotherapy (LITT) of liver metastases: MR-guided percutaneous insertion of an MRI-compatible irrigated microcatheter system using a closed high-field unit
    Ralf Puls
    Radiology Departments, Charite, Humboldt University of Berlin, Germany
    J Magn Reson Imaging 17:663-70. 2003
    ..To evaluate the efficacy and safety of a new MRI-compatible irrigated laser microcatheter system for thermal ablation of liver metastases...
  14. ncbi Cytokine profiles after nonionic dimeric contrast medium injection
    Ingrid Böhm
    Department of Radiology, University of Bonn, 53105 Bonn, Germany
    Invest Radiol 38:776-83. 2003
    ..We evaluated the possibility of cytokines released as surrogate markers for allergic/pseudoallergic responses in patients who tolerated CM injection well...
  15. ncbi Paradigms and perspectives in contrast media research
    Ulrich Speck
    Department of Radiology, Charit, Humboldt University, Berlin, Germany
    Acad Radiol 9:S392-7. 2002
  16. ncbi Paclitaxel balloon coating, a novel method for prevention and therapy of restenosis
    Bruno Scheller
    Department of Internal Medicine III Cardiology Angiology, University of Saarland, Homburg Saar, Germany
    Circulation 110:810-4. 2004
    ..The aim of the present study was to evaluate a novel method of local drug delivery based on angioplasty balloons...
  17. ncbi Contrast media as carriers for local drug delivery. Successful inhibition of neointimal proliferation in the porcine coronary stent model
    Bruno Scheller
    Internal Medicine III, University of Saarland, D 66421 Homburg Saar, Germany
    Eur Heart J 24:1462-7. 2003
    ..The aim of this study was to test a novel taxane-contrast agent formulation for this new approach in the setting of coronary stenting...
  18. ncbi Addition of paclitaxel to contrast media prevents restenosis after coronary stent implantation
    Bruno Scheller
    Internal Medicine III Cardiology Angiology, University of Saarland, Homburg Saar, Germany
    J Am Coll Cardiol 42:1415-20. 2003
    ..The present study was designed to test the efficacy of paclitaxel added to the contrast agent iopromide in the prevention of restenosis...
  19. ncbi Three-dimensional gradient-echo imaging for percutaneous MR-guided laser therapy of liver metastasis
    Ralf Puls
    Radiology Department, University Hospital, Ernst Moritz Arndt University of Greifswald, Fr Löfflerstrasse 23, 17475 Greifswald, Germany
    J Magn Reson Imaging 25:1174-8. 2007
    ..To evaluate the use of three-dimensional (3D) gradient-echo (GRE) magnetic resonance imaging (MRI) for percutaneous MR-guided catheter placement for laser therapy of liver metastases...
  20. ncbi Treatment of coronary in-stent restenosis with a paclitaxel-coated balloon catheter
    Bruno Scheller
    Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    N Engl J Med 355:2113-24. 2006
    ..Treatment of coronary in-stent restenosis is hampered by a high incidence of recurrent in-stent restenosis. We assessed the efficacy and safety of a paclitaxel-coated balloon in this setting...
  21. ncbi Acute cardiac tolerance of current contrast media and the new taxane protaxel using iopromide as carrier during porcine coronary angiography and stenting
    Bruno Scheller
    Internal Medicine III Cardiology, University of Saarland, Homburg Saar, Germany
    Invest Radiol 37:29-34. 2002
    ..The aim of this study was to comparatively evaluate the cardiovascular tolerability of iopromide, ioxaglate, and iosmin, and of a novel taxane protaxel, dissolved in iopromide, as a carrier, by coronary angiography and stenting...
  22. ncbi Local delivery of paclitaxel to inhibit restenosis during angioplasty of the leg
    Gunnar Tepe
    Radiologische Klinik, Diagnostische und Interventionelle Radiologie, Eberhard Karls Universitat, Tubingen, Germany
    N Engl J Med 358:689-99. 2008
    ..We investigated the use of paclitaxel-coated angioplasty balloons and paclitaxel dissolved in the angiographic contrast medium during angioplasty of the leg...
  23. ncbi Prevention of restenosis: is angioplasty the answer?
    Bruno Scheller
    Heart 93:539-41. 2007
    ..quot;The drug-coated balloon has the potential to improve the limited results of drug-eluting stents"..